Case-only design to measure gene-gene interaction

Epidemiology

Volumn 10, Issue 2, 1999, Pages 167-170

  Yang, Quanhe ^a   Khoury, Muin J ^b   Sun, Fengzhu ^c   Flanders, W Dana ^d  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d EMORY UNIVERSITY   (United States)

Author keywords

Case only design; Epidemiologic methods; Gene gene interaction; Genes; Study design

Indexed keywords

ARTICLE; DISEASE PREDISPOSITION; GENE; GENE FREQUENCY; GENE MUTATION; GENOTYPE; HUMAN; PRIORITY JOURNAL;

EID: 0032915780     PISSN: 10443983     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001648-199903000-00014     Document Type: Article

References (29)

1. Khoury MJ. Genetic epidemiology. In: Rothman KJ, Greenland S, eds. Modern Epidemiology. Philadelphia: Lippincott-Raven, 1998;609-622.
2. Whitehead AS, Gallagher P, Mills JL, Kirke PN, Burke H, Molloy AM, Weir DG, Shields DC, Scott JM. A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects. QJM 1995;88:763-766.
3. Van der Put NM, Steegers-Theunissen RP, Frosst P, Trijbels FJ, Eskes TK, van den Heuvel LP, Mariman EC, den Heyer M, Rozen R, Blom HJ. Mutated methylenetetrahydrofolate reductase as a risk factor for spinal bifida. Lancet 1995;346:1070-1071.
4. Ou CY, Stevenson RE, Brown VK, Schwartz CE, Allen WP, Khoury MJ, Rozen R, Oakley GP Jr, Adams MJ Jr. 5,10 methylenetetrahydrofolate reductase genetic polymorphism as a risk factor for neural tube defects. Am J Med Genet 1996;63:610-614.
5. Ramsbottom D, Scott JM, Molloy A, Weir DG, Kirke PN, Mills JL, Gallapher PM, Whitehead AS. Are common mutations of cystathionine beta-synthase involved in the aetiology of neural tube defects? Clin Genet 1997;51:39-42.
6. Galinsky D, Tysoe C, Brayne CE, Easton DF, Huppert FA, Dening TR, Paykel ES, Rubinsztein DC. Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity. Atherosclerosis 1997;129:177-183.
7. Grandone E, Margaglione M, Colaizzo D, Cappucci G, Paladini D, Martinelli P, Monranaro S, Pavone G, Di Minno G. Factor V Leiden, C>T MTHFR polymorphism and genetic susceptibility to preeclampsia. Thromb Haemost. 1997;77:1052-1054.
8. Jarvik G, Larson EB, Goddard K, Schellenberg GD, Wijsman EM. Influence of apolipoprotein E genotype on the transmission of Alzheimer disease in a community-based sample. Am J Hum Genet 1996;58:191-200.
9. MacLeod S, Sinha R, Kadlubar FF, Lang NP. Polymorphism of CTP1A1 and GSTM1 influence the in vivo function of CYP1A2. Mutat Res 1997;376: 135-142.
10. Beales PL, Kopelman PG. Obesity genes. Clin Endocrinol 1996;45:373-378.
11. Williams RR, Hunt SC, Hopkins PN, Wu LL, Hasstedt SJ, Berry TD, Barlow GK, Stults BM, Schumacher MC, Ludwig EH. Genetic basis of familial dyslipidemia and hypertension: 15-year results from Utah. Am J Hypertens 1993:6(11 pt 2):319S-27S.
12. Davignon J, Roy M. Familial hypercholesterolemia in French-Canadians: taking advantage of the presence of a "founder effect." Am J Cardiol 1993;72:6D-10D.
13. Piegorsch WW, Weinberg CR, Taylor JA. Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies. Stat Med 1994;13:153-162.
14. Begg CB, Zhang ZF. Statistical analysis of molecular epidemiology studies employing case-series. Cancer Epidemiol Biomarkers Prev 1994;3:173-175.
15. Botto LD, Mastroiacovo P. Exploring gene-gene interactions in the etiology of neural tube defects. Clin Genet 1998;53:456-459.
16. Yang QH, Khoury MJ, Flanders WD. Sample size requirements in case-only designs to detect gene-environment interaction. Am J Epidemiol 1997;146: 713-720.
17. Koopman JS. Causal models and sources of interaction. Am J Epidemiol 1977;106:439-444.
18. Rothman KJ, Greenland S, Walker AM. Concepts of interaction. Am J Epidemiol 1980;112:467-470.
19. Siemiatycki J, Thomas DC. Biological models and statistical interactions. Int J Epidemiol 1981;10:383-387.
20. Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic Research. New York: Van Nostrand Reinhold, 1982.
21. Miettinen OS. Causal and preventive interdependence: elementary principles. Scand J Work Environ Health 1982;18:159-168.
22. Greenland S. Tests for interaction in epidemiologic studies: a review and a study of power. Stat Med 1983;2:243-251.
23. Greenland S, Poole C. Invariants and noninvariants in the concept of interdependent effects. Scand J Work Environ Health 1988;14:125-129.
24. Pearce N. Analytical implications of epidemiological concepts of interaction. Int J Epidemiol 1989;18:976-980.
25. Thompson WD. Effect modification and the limits of biological inference from epidemiologic data. J Clin Epidemiol 1991;44:221-232.
26. Greenland S. Basic problems in interaction assessment. Environ Health Perspect 1993;101(suppl 4):59-66.
27. Rothman KJ, Greenland S. Modern Epidemiology. Philadelphia: Lippincott-Raven, 1998.
28. Khoury MJ, Flanders WD. Non-traditional epidemiologic approaches in the analysis of gene-environment interaction: case-control studies with no controls! Am J Epidemiol 1996;144:207-213.
29. Yang QH, Khoury MJ. Evolving methods in genetic epidemiology, III: gene-environment interaction in epidemiologic research. Epidemiol Rev 1997;19:33-43.