Heat shock protein 90 positively regulates Chikungunya virus replication by stabilizing viral non-structural protein nsP2 during infection

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Das, Indrani ^a   Basantray, Itishree ^a   Mamidi, Prabhudutta ^a   Nayak, Tapas K ^b   Pratheek, B M ^b   Chattopadhyay, Subhasis ^b   Chattopadhyay, Soma ^a  

^a INSTITUTE OF LIFE SCIENCES   (India)

^b NATIONAL INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; NONSTRUCTURAL PROTEIN 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN S6K; UNCLASSIFIED DRUG; VIRUS RNA; ANTIVIRUS AGENT; BENZOQUINONE DERIVATIVE; MACROCYCLIC LACTAM; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CHIKUNGUNYA; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; IMMUNOPRECIPITATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION; VIRUS RELEASE; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TITRATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; VERO CELL LINE;

ANIMALS; ANTIVIRAL AGENTS; BENZOQUINONES; CERCOPITHECUS AETHIOPS; CHIKUNGUNYA VIRUS; HSP90 HEAT-SHOCK PROTEINS; LACTAMS, MACROCYCLIC; PROTEIN BIOSYNTHESIS; PROTEIN STABILITY; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS RELEASE; VIRUS REPLICATION;

EID: 84903527306     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100531     Document Type: Article

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