Palmitate has proapoptotic and proinflammatory effects on articular cartilage and synergizes with interleukin-1

Arthritis and Rheumatology

Volumn 66, Issue 7, 2014, Pages 1779-1788

  Alvarez Garcia, Oscar ^a   Rogers, Nicole H ^b   Smith, Roy G ^c   Lotz, Martin K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b California Institute for Biomedical Research   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; INTERLEUKIN 6; OLEIC ACID; PALMITIC ACID; PROTEINASE; TOLL LIKE RECEPTOR 4;

ADULT; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL DEATH; CELL VIABILITY; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNOVIOCYTE; TOTAL KNEE REPLACEMENT; UPREGULATION;

ADULT; AGED; ANIMALS; APOPTOSIS; CARTILAGE, ARTICULAR; CATTLE; CELLS, CULTURED; CHONDROCYTES; CYCLOOXYGENASE 2; DRUG SYNERGISM; EXTRACELLULAR MATRIX; FATTY ACIDS, NONESTERIFIED; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MIDDLE AGED; OLEIC ACID; OSTEOARTHRITIS, KNEE; PALMITATES; SYNOVIAL MEMBRANE; TOLL-LIKE RECEPTOR 4; YOUNG ADULT;

EID: 84903487105     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38399     Document Type: Article

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