Acylation in trypanosomatids: An essential process and potential drug target

Trends in Parasitology

Volumn 30, Issue 7, 2014, Pages 350-360

  Goldston, Amanda M ^a   Sharma, Aabha I ^a   Paul, Kimberly S ^b   Engman, David M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b CLEMSON UNIVERSITY   (United States)

Author keywords

Myristoylation; Palmitoylation; Trafficking; Virulence

Indexed keywords

ANTITRYPANOSOMAL AGENT; FATTY ACID; MYRISTIC ACID; PALMITIC ACID; PROTEIN N MYRISTOYLTRANSFERASE;

ACYLATION; AFRICAN TRYPANOSOMIASIS; CELL DEATH; DRUG TARGETING; KINETOPLASTIDA; LEISHMANIA; MYRISTYLATION; NONHUMAN; PALMITOYLATION; PARASITE LOCALIZATION; PARASITE SURVIVAL; PARASITE VIRULENCE; PARASITOSIS; PROTEIN FUNCTION; REVIEW; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

RODENTIA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; TRYPANOSOMATIDAE;

MYRISTOYLATION; PALMITOYLATION; TRAFFICKING; VIRULENCE;

ACYLATION; ACYLTRANSFERASES; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; ENZYME INHIBITORS; TRYPANOSOMATINA;

EID: 84903483348     PISSN: 14714922     EISSN: 14715007     Source Type: Journal    
DOI: 10.1016/j.pt.2014.05.003     Document Type: Review

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