Discovery and characterization of inhibitors of human palmitoyl acyltransferases

Molecular Cancer Therapeutics

Volumn 5, Issue 7, 2006, Pages 1647-1659

  Ducker, Charles E ^a   Griffel, Lindsay K ^b   Smith, Ryan A ^b   Keller, Staci N ^a   Zhuang, Yan ^a   Xia, Zuping ^c   Diller, John D ^d   Smith, Charles D ^a,b,c  

^a APOGEE BIOTECHNOLOGY CORPORATION   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZYL 4 (5 CHLORO 2 NITROBENZYL)PIPERAZINE; 11 METHYL 4 (4 NITROBENZYL) 1,2,3,3A,4,5,6,7 OCTAHYDRO[1,4]DIAZEPINO[3,2,1 JK]CARBAZOLE; 2 (2 FLUOROBENZYL) 1 PHENYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRAZINE; 2 (2 HYDROXY 5 NITROBENZYLIDENE)BENZO[B]THIOPEN 3 ONE; [2 [2 (4 CHLOROPHENYL) 1,3A,8 TRIAZACYCLOPENTA[A]INDEN 1 YL]ETHYL]DIETHYLAMINE; ACYLTRANSFERASE; ACYLTRANSFERASE INHIBITOR; ANTINEOPLASTIC AGENT; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; PALMITOYL ACYLTRANSFERASE; PALMITOYL ACYLTRANSFERASE INHIBITOR; PROTEIN HIP14; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL MEMBRANE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETERMINATION; DRUG RESEARCH; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; FEMALE; GENETIC CODE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN TARGETING; UPREGULATION;

ACYLTRANSFERASES; ANTINEOPLASTIC AGENTS; CARRIER PROTEINS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; NEOPLASMS; NERVE TISSUE PROTEINS; RAS PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 33748299575     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0114     Document Type: Article

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