메뉴 건너뛰기




Volumn 436, Issue , 2014, Pages 243-248

The expression of VEGF and Dll4/Notch pathway molecules in ovarian cancer

Author keywords

Angiogenesis; Dll4 Notch; Ovarian cancer; VEGF

Indexed keywords

CD34 ANTIGEN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR; PROTEIN DLL4; TUMOR PROMOTER; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; DELTA PROTEIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; RECEPTORS, NOTCH; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84903434928     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2014.06.005     Document Type: Article
Times cited : (37)

References (47)
  • 3
    • 12944315020 scopus 로고    scopus 로고
    • Epithelial ovarian cancer: prevention, diagnosis, and treatment
    • Partridge E.E., Barnes M.N. Epithelial ovarian cancer: prevention, diagnosis, and treatment. CA Cancer J Clin 1999, 49:297-320.
    • (1999) CA Cancer J Clin , vol.49 , pp. 297-320
    • Partridge, E.E.1    Barnes, M.N.2
  • 5
    • 41849092178 scopus 로고    scopus 로고
    • Angiogenesis as a strategic target for ovarian cancer therapy
    • Spannuth W.A., Sood A.K., Coleman R.L. Angiogenesis as a strategic target for ovarian cancer therapy. Nat Clin Pract Oncol 2008, 5:194-204.
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 194-204
    • Spannuth, W.A.1    Sood, A.K.2    Coleman, R.L.3
  • 6
    • 33947545030 scopus 로고    scopus 로고
    • Tumor vascular proteins as biomarkers in ovarian cancer
    • Buckanovich R.J., Sasaroli D., O'Brien-Jenkins A., et al. Tumor vascular proteins as biomarkers in ovarian cancer. J Clin Oncol 2007, 25:852-861.
    • (2007) J Clin Oncol , vol.25 , pp. 852-861
    • Buckanovich, R.J.1    Sasaroli, D.2    O'Brien-Jenkins, A.3
  • 7
    • 84862127138 scopus 로고    scopus 로고
    • Current knowledge and open issues regarding Bevacizumab in gynaecological neoplasms
    • Bellati F., Napoletano C., Gasparri M.L., et al. Current knowledge and open issues regarding Bevacizumab in gynaecological neoplasms. Crit Rev Oncol Hematol Jul 2012, 83:35-46.
    • (2012) Crit Rev Oncol Hematol , vol.83 , pp. 35-46
    • Bellati, F.1    Napoletano, C.2    Gasparri, M.L.3
  • 8
    • 70350566692 scopus 로고    scopus 로고
    • Sustained progression-free survival with weekly paclitaxel and bevacizumab in recurrent ovarian cancer
    • Hurt J.D., Richardson D.L., Seamon L.G., et al. Sustained progression-free survival with weekly paclitaxel and bevacizumab in recurrent ovarian cancer. Gynecol Oncol 2009, 115:396-400.
    • (2009) Gynecol Oncol , vol.115 , pp. 396-400
    • Hurt, J.D.1    Richardson, D.L.2    Seamon, L.G.3
  • 9
    • 77649213706 scopus 로고    scopus 로고
    • Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2
    • Spratlin J.L., Cohen R.B., Eadens M., et al. Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2. J Clin Oncol 2010, 28:780-787.
    • (2010) J Clin Oncol , vol.28 , pp. 780-787
    • Spratlin, J.L.1    Cohen, R.B.2    Eadens, M.3
  • 10
    • 33745092023 scopus 로고    scopus 로고
    • Notch signaling in the regulation of tumor angiogenesis
    • Rehman A.O., Wang C.Y. Notch signaling in the regulation of tumor angiogenesis. Trends Cell Biol 2006, 16:293-300.
    • (2006) Trends Cell Biol , vol.16 , pp. 293-300
    • Rehman, A.O.1    Wang, C.Y.2
  • 11
    • 0037216703 scopus 로고    scopus 로고
    • Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis
    • Liu Z.J., Shirakawa T., Li Y., et al. Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol 2003, 23:14-25.
    • (2003) Mol Cell Biol , vol.23 , pp. 14-25
    • Liu, Z.J.1    Shirakawa, T.2    Li, Y.3
  • 12
    • 80052816881 scopus 로고    scopus 로고
    • Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer
    • Hu W., Lu C., Dong H.H., et al. Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer. Cancer Res 2011, 71:6030-6039.
    • (2011) Cancer Res , vol.71 , pp. 6030-6039
    • Hu, W.1    Lu, C.2    Dong, H.H.3
  • 13
    • 60449117723 scopus 로고    scopus 로고
    • Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: a Gynecologic Oncology Group study
    • Rubatt J.M., Darcy K.M., Hutson A., et al. Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: a Gynecologic Oncology Group study. Gynecol Oncol 2009, 112:469-474.
    • (2009) Gynecol Oncol , vol.112 , pp. 469-474
    • Rubatt, J.M.1    Darcy, K.M.2    Hutson, A.3
  • 14
    • 0029127219 scopus 로고
    • Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors
    • Weidner N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat 1995, 36:169-180.
    • (1995) Breast Cancer Res Treat , vol.36 , pp. 169-180
    • Weidner, N.1
  • 15
    • 0034648793 scopus 로고    scopus 로고
    • Vascular-specific growth factors and blood vessel formation
    • Yancopoulos G.D., Davis S., Gale N.W., et al. Vascular-specific growth factors and blood vessel formation. Nature 2000, 407:242-248.
    • (2000) Nature , vol.407 , pp. 242-248
    • Yancopoulos, G.D.1    Davis, S.2    Gale, N.W.3
  • 16
    • 33947414473 scopus 로고    scopus 로고
    • VEGF-A and the induction of pathological angiogenesis
    • Nagy J.A., Dvorak A.M., Dvorak H.F. VEGF-A and the induction of pathological angiogenesis. Annu Rev Pathol 2007, 2:251-275.
    • (2007) Annu Rev Pathol , vol.2 , pp. 251-275
    • Nagy, J.A.1    Dvorak, A.M.2    Dvorak, H.F.3
  • 17
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N., Gerber H.P., Lecouter J., et al. The biology of VEGF and its receptors. Nat Med 2003, 9:669-676.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 18
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • Carmeliet P. Angiogenesis in health and disease. Nat Med 2003, 9:653-660.
    • (2003) Nat Med , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 19
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain R.K. Molecular regulation of vessel maturation. Nat Med 2003, 9:685-693.
    • (2003) Nat Med , vol.9 , pp. 685-693
    • Jain, R.K.1
  • 20
    • 0029929716 scopus 로고    scopus 로고
    • The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis
    • Clauss M., Weich H., Breier G., et al. The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem 1996, 271:17629-17634.
    • (1996) J Biol Chem , vol.271 , pp. 17629-17634
    • Clauss, M.1    Weich, H.2    Breier, G.3
  • 21
    • 0030923795 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in early stage ovarian carcinoma
    • Paley P.J., Staskus K.A., Gebhard K., et al. Vascular endothelial growth factor expression in early stage ovarian carcinoma. Cancer 1997, 80:98-106.
    • (1997) Cancer , vol.80 , pp. 98-106
    • Paley, P.J.1    Staskus, K.A.2    Gebhard, K.3
  • 22
    • 1842850792 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and interleukin-8 are associated with poor prognosis in epithelial ovarian cancer patients
    • Kassim S.K., El-Salahy E.M., Fayed S.T., et al. Vascular endothelial growth factor and interleukin-8 are associated with poor prognosis in epithelial ovarian cancer patients. Clin Biochem 2004, 37:363-369.
    • (2004) Clin Biochem , vol.37 , pp. 363-369
    • Kassim, S.K.1    El-Salahy, E.M.2    Fayed, S.T.3
  • 23
    • 0036793818 scopus 로고    scopus 로고
    • Preoperative serum vascular endothelial growth factor levels: significance in ovarian cancer
    • Cooper B.C., Ritchie J.M., Broghammer C.L., et al. Preoperative serum vascular endothelial growth factor levels: significance in ovarian cancer. Clin Cancer Res 2002, 8:3193-3197.
    • (2002) Clin Cancer Res , vol.8 , pp. 3193-3197
    • Cooper, B.C.1    Ritchie, J.M.2    Broghammer, C.L.3
  • 24
    • 3242658330 scopus 로고    scopus 로고
    • Correlation of serum VEGF levels with clinical stage, therapy efficacy, tumor metastasis and patient survival in ovarian cancer
    • Li L., Wang L., Zhang W., et al. Correlation of serum VEGF levels with clinical stage, therapy efficacy, tumor metastasis and patient survival in ovarian cancer. Anticancer Res 2004, 24:1973-1979.
    • (2004) Anticancer Res , vol.24 , pp. 1973-1979
    • Li, L.1    Wang, L.2    Zhang, W.3
  • 25
    • 33751006991 scopus 로고    scopus 로고
    • Preoperative serum vascular endothelial growth factor as a prognostic parameter in ovarian cancer
    • Hefler L.A., Zeillinger R., Grimm C., et al. Preoperative serum vascular endothelial growth factor as a prognostic parameter in ovarian cancer. Gynecol Oncol 2006, 103:512-517.
    • (2006) Gynecol Oncol , vol.103 , pp. 512-517
    • Hefler, L.A.1    Zeillinger, R.2    Grimm, C.3
  • 26
    • 61449097778 scopus 로고    scopus 로고
    • Circulating vascular endothelial growth factors and their soluble receptors in pre-invasive, invasive and recurrent cervical cancer
    • Kuemmel S., Thomas A., Landt S., et al. Circulating vascular endothelial growth factors and their soluble receptors in pre-invasive, invasive and recurrent cervical cancer. Anticancer Res 2009, 29:641-645.
    • (2009) Anticancer Res , vol.29 , pp. 641-645
    • Kuemmel, S.1    Thomas, A.2    Landt, S.3
  • 27
    • 60449083456 scopus 로고    scopus 로고
    • Markers of angiogenesis in high-risk, early-stage cervical cancer: a Gynecologic Oncology Group study
    • Randall L.M., Monk B.J., Darcy K.M., et al. Markers of angiogenesis in high-risk, early-stage cervical cancer: a Gynecologic Oncology Group study. Gynecol Oncol 2009, 112:583-589.
    • (2009) Gynecol Oncol , vol.112 , pp. 583-589
    • Randall, L.M.1    Monk, B.J.2    Darcy, K.M.3
  • 28
    • 4444324696 scopus 로고    scopus 로고
    • VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma
    • Chen H., Ye D., Xie X., Chen B., Lu W. VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma. Gynecol Oncol 2004, 94:630-635.
    • (2004) Gynecol Oncol , vol.94 , pp. 630-635
    • Chen, H.1    Ye, D.2    Xie, X.3    Chen, B.4    Lu, W.5
  • 29
    • 33846933952 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) pathway as a therapeutic target in gynecologic malignancies
    • Frumovitz M., Sood A.K. Vascular endothelial growth factor (VEGF) pathway as a therapeutic target in gynecologic malignancies. Gynecol Oncol 2007, 104:768-778.
    • (2007) Gynecol Oncol , vol.104 , pp. 768-778
    • Frumovitz, M.1    Sood, A.K.2
  • 30
    • 33746439031 scopus 로고    scopus 로고
    • Enhanced in vitro invasiveness of ovarian cancer cells through up-regulation of VEGF and induction of MMP-2
    • Zhang A., Meng L., Wang Q., et al. Enhanced in vitro invasiveness of ovarian cancer cells through up-regulation of VEGF and induction of MMP-2. Oncol Rep 2006, 15:831-836.
    • (2006) Oncol Rep , vol.15 , pp. 831-836
    • Zhang, A.1    Meng, L.2    Wang, Q.3
  • 31
    • 63849310246 scopus 로고    scopus 로고
    • Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implications
    • Li J.L., Harris A.L. Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implications. Front Biosci (Landmark Ed) 2009, 14:3094-3110.
    • (2009) Front Biosci (Landmark Ed) , vol.14 , pp. 3094-3110
    • Li, J.L.1    Harris, A.L.2
  • 32
    • 53849106782 scopus 로고    scopus 로고
    • VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis
    • Thurston G., Kitajewski J. VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis. Br J Cancer 2008, 99:1204-1209.
    • (2008) Br J Cancer , vol.99 , pp. 1204-1209
    • Thurston, G.1    Kitajewski, J.2
  • 33
    • 80255135606 scopus 로고    scopus 로고
    • Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo
    • Stenzel D., Franco C.A., Estrach S., et al. Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo. EMBO Rep 2011, 12:1135-1143.
    • (2011) EMBO Rep , vol.12 , pp. 1135-1143
    • Stenzel, D.1    Franco, C.A.2    Estrach, S.3
  • 34
    • 33846040204 scopus 로고    scopus 로고
    • Critical role of endothelial Notch1 signaling in postnatal angiogenesis
    • Takeshita K., Satoh M., Ii M., et al. Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circ Res 2007, 100:70-78.
    • (2007) Circ Res , vol.100 , pp. 70-78
    • Takeshita, K.1    Satoh, M.2    Ii, M.3
  • 36
    • 50849103301 scopus 로고    scopus 로고
    • Notch signaling regulates tumor angiogenesis by diverse mechanisms
    • Dufraine J., Funahashi Y., Kitajewski J. Notch signaling regulates tumor angiogenesis by diverse mechanisms. Oncogene 2008, 27:5132-5137.
    • (2008) Oncogene , vol.27 , pp. 5132-5137
    • Dufraine, J.1    Funahashi, Y.2    Kitajewski, J.3
  • 37
    • 30744477450 scopus 로고    scopus 로고
    • Lymphangiogenesis in development and human disease
    • Alitalo K., Tammela T., Petrova T.V. Lymphangiogenesis in development and human disease. Nature 2005, 438:946-953.
    • (2005) Nature , vol.438 , pp. 946-953
    • Alitalo, K.1    Tammela, T.2    Petrova, T.V.3
  • 38
    • 0037370310 scopus 로고    scopus 로고
    • Notch1 functions as a tumor suppressor in mouse skin
    • Nicolas M., Wolfer A., Raj K., et al. Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 2003, 33:416-421.
    • (2003) Nat Genet , vol.33 , pp. 416-421
    • Nicolas, M.1    Wolfer, A.2    Raj, K.3
  • 39
    • 27144504699 scopus 로고    scopus 로고
    • The Notch pathway in ovarian carcinomas and adenomas
    • Hopfer O., Zwahlen D., Fey M.F., et al. The Notch pathway in ovarian carcinomas and adenomas. Br J Cancer 2005, 93:709-718.
    • (2005) Br J Cancer , vol.93 , pp. 709-718
    • Hopfer, O.1    Zwahlen, D.2    Fey, M.F.3
  • 40
    • 25444506836 scopus 로고    scopus 로고
    • Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
    • Patel N.S., Li J.L., Generali D., et al. Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res 2005, 65:8690-8697.
    • (2005) Cancer Res , vol.65 , pp. 8690-8697
    • Patel, N.S.1    Li, J.L.2    Generali, D.3
  • 41
    • 33749012860 scopus 로고    scopus 로고
    • The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions
    • Hainaud P., Contreres J.O., Villemain A., et al. The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions. Cancer Res 2006, 66:8501-8510.
    • (2006) Cancer Res , vol.66 , pp. 8501-8510
    • Hainaud, P.1    Contreres, J.O.2    Villemain, A.3
  • 42
    • 33845907380 scopus 로고    scopus 로고
    • Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
    • Ridgway J., Zhang G., Wu Y., et al. Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature 2006, 444:1083-1087.
    • (2006) Nature , vol.444 , pp. 1083-1087
    • Ridgway, J.1    Zhang, G.2    Wu, Y.3
  • 43
    • 33847046849 scopus 로고    scopus 로고
    • Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
    • Hellstrom M., Phng L.K., Hofmann J.J., et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 2007, 445:776-7780.
    • (2007) Nature , vol.445 , pp. 776-7780
    • Hellstrom, M.1    Phng, L.K.2    Hofmann, J.J.3
  • 44
    • 33847635620 scopus 로고    scopus 로고
    • Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting
    • Lobov I.B., Renard R.A., Papadopoulos N., et al. Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc Natl Acad Sci U S A 2007, 104:3219-3224.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3219-3224
    • Lobov, I.B.1    Renard, R.A.2    Papadopoulos, N.3
  • 45
    • 33847607880 scopus 로고    scopus 로고
    • The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching
    • Suchting S., Freitas C., le Noble F., et al. The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. Proc Natl Acad Sci U S A 2007, 104:3225-3230.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3225-3230
    • Suchting, S.1    Freitas, C.2    le Noble, F.3
  • 46
    • 0036433637 scopus 로고    scopus 로고
    • Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression
    • Taylor K.L., Henderson A.M., Hughes C.C. Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression. Microvasc Res 2002, 64:372-383.
    • (2002) Microvasc Res , vol.64 , pp. 372-383
    • Taylor, K.L.1    Henderson, A.M.2    Hughes, C.C.3
  • 47
    • 39149123515 scopus 로고    scopus 로고
    • Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells
    • Harrington L.S., Sainson R.C., Williams C.K., et al. Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells. Microvasc Res 2008, 75:144-154.
    • (2008) Microvasc Res , vol.75 , pp. 144-154
    • Harrington, L.S.1    Sainson, R.C.2    Williams, C.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.