Epigenetic genes and emotional reactivity to daily life events: A multi-step gene-environment interaction study

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Pishva, Ehsan ^a   Drukker, Marjan ^a   Viechtbauer, Wolfgang ^a   Decoster, Jeroen ^a   Collip, Dina ^a   Van Winkel, Ruud ^a   Wichers, Marieke ^a   Jacobs, Nele ^a,b   Thiery, Evert ^c   Derom, Catherine ^d   Geschwind, Nicole ^e   Van Den Hove, Daniel ^a,f   Lataster, Tineke ^a   Myin Germeys, Inez ^a   Van Os, Jim ^a,g   Rutten, Bart P F ^a   Kenis, Gunter ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b OPEN UNIVERSITY OF THE NETHERLANDS   (Netherlands)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f UNIVERSITY OF WÜRZBURG   (Germany)

^g KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); DNA METHYLTRANSFERASE;

ADULT; ANAMNESIS; ARTICLE; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DISEASE ASSOCIATION; DNMT1 GENE; DNMT3A GENE; DNMT3B GENE; EMOTIONAL STRESS; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC CORRELATION; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MTHFR GENE; POPULATION RESEARCH; PSYCHOSIS; REGULATOR GENE; SIBLING RELATION; SINGLE NUCLEOTIDE POLYMORPHISM; EMOTION; GENETIC EPIGENESIS; MENTAL STRESS; MIDDLE AGED; PLEASURE; YOUNG ADULT;

ADULT; EMOTIONS; EPIGENESIS, GENETIC; FEMALE; GENE-ENVIRONMENT INTERACTION; HUMANS; MALE; MIDDLE AGED; PLEASURE; POLYMORPHISM, SINGLE NUCLEOTIDE; STRESS, PSYCHOLOGICAL; YOUNG ADULT;

EID: 84903388645     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100935     Document Type: Article

References (49)

1. Myin-Germeys I, van Os J, Schwartz JE, Stone AA, Delespaul PA (2001) Emotional reactivity to daily life stress in psychosis. Archives of general psychiatry 58: 1137-1144. (Pubitemid 33121505)
2. Myin-Germeys I, Peeters F, Havermans R, Nicolson NA, DeVries MW, et al. (2003) Emotional reactivity to daily life stress in psychosis and affective disorder: an experience sampling study. Acta psychiatrica Scandinavica 107: 124-131. (Pubitemid 36164480)
3. Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, et al. (2004) Epigenetic programming by maternal behavior. Nature neuroscience 7: 847-854. (Pubitemid 38989508)
4. Pishva E, Kenis G, Lesch KP, Prickaerts J, Steinbusch HMW, et al. (2012) Epigenetic epidemiology in psychiatry: A translational neuroscience perspective. Translational Neuroscience 3: 196-212.
5. Tsumura A, Hayakawa T, Kumaki Y, Takebayashi S, Sakaue M, et al. (2006) Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes to Cells 11: 805-814. (Pubitemid 43923351)
6. Okano M, Bell DW, Haber DA, Li E (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99: 247-257. (Pubitemid 29519904)
7. Friso S, Choi SW, Girelli D, Mason JB, Dolnikowski GG, et al. (2002) A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proceedings of the National Academy of Sciences of the United States of America 99: 5606-5611. (Pubitemid 34411596)
8. Yang X, Ewald ER, Huo Y, Tamashiro KL, Salvatori R, et al. (2012) Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5. Biochemical and biophysical research communications 420: 570-575.
9. Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, et al. (2008) Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics: official journal of the DNA Methylation Society 3: 97-106.
10. Murgatroyd C, Patchev AV, Wu Y, Micale V, Bockmuhl Y, et al. (2009) Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nature neuroscience 12: 1559-1566.
11. Kember RL, Dempster EL, Lee TH, Schalkwyk LC, Mill J, et al. (2012) Maternal separation is associated with strain-specific responses to stress and epigenetic alterations to Nr3c1, Avp, and Nr4a1 in mouse. Brain and behavior 2: 455-467.
12. Melas PA, Wei Y, Wong CC, Sjoholm LK, Aberg E, et al. (2013) Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities. The international journal of neuropsychopharmacology/official scientific journal of the Collegium Internationale Neuropsychopharmacologicum: 1-16.
13. McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonte B, et al. (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nature neuroscience 12: 342-348.
14. Mill J, Dempster E, Caspi A, Williams B, Moffitt T, et al. (2006) Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene. American journal of medical genetics Part B, Neuropsychiatric genetics: the official publication of the International Society of Psychiatric Genetics 141B: 421-425.
15. Ouellet-Morin I, Wong CC, Danese A, Pariante CM, Papadopoulos AS, et al. (2012) Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins. Psychological medicine: 1-11.
16. Souren NY, Lutsik P, Gasparoni G, Tierling S, Gries J, et al. (2013) Adult monozygotic twins discordant for intra-uterine growth have indistinguishable genome-wide DNA methylation profiles. Genome biology 14: R44.
17. Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, et al. (2010) Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nature neuroscience 13: 1338-1344.
18. Unternaehrer E, Luers P, Mill J, Dempster E, Meyer AH, et al. (2012) Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF) after acute psychosocial stress. Translational psychiatry 2: e150.
19. Myin-Germeys I, Oorschot M, Collip D, Lataster J, Delespaul P, et al. (2009) Experience sampling research in psychopathology: opening the black box of daily life. Psychological medicine 39: 1533-1547.
20. Johns LC, van Os J (2001) The continuity of psychotic experiences in the general population. Clinical psychology review 21: 1125-1141. (Pubitemid 33033121)
21. Frissen A, Lieverse R, Drukker M, Delespaul P, Lataster T, et al. (2014) Evidence that childhood urban environment is associated with blunted stress reactivity across groups of patients with psychosis, relatives of patients and controls. Social psychiatry and psychiatric epidemiology.
22. Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, et al. (2013) Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature genetics 45: 984-994.
23. Duncan LE, Keller MC (2011) A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry. The American journal of psychiatry 168: 1041-1049.
24. Derom CA, Vlietinck RF, Thiery EW, Leroy FO, Fryns JP, et al. (2006) The East Flanders Prospective Twin Survey (EFPTS). Twin research and human genetics: the official journal of the International Society for Twin Studies 9: 733-738.
25. Jacobs N, Nicolson NA, Derom C, Delespaul P, van Os J, et al. (2005) Electronic monitoring of salivary cortisol sampling compliance in daily life. Life sciences 76: 2431-2443. (Pubitemid 40341960)
26. Kay SR, Fiszbein A, Opler LA (1987) The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin 13: 261-276. (Pubitemid 18039085)
27. McGuffin P, Farmer A, Harvey I (1991) A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system. Archives of general psychiatry 48: 764-770.
28. Geschwind N, Peeters F, Drukker M, van Os J, Wichers M (2011) Mindfulness training increases momentary positive emotions and reward experience in adults vulnerable to depression: a randomized controlled trial. Journal of consulting and clinical psychology 79: 618-628.
29. Collip D, Nicolson NA, Lardinois M, Lataster T, van Os J, et al. (2011) Daily cortisol, stress reactivity and psychotic experiences in individuals at above average genetic risk for psychosis. Psychological medicine 41: 2305-2315.
30. Thewissen V, Bentall RP, Lecomte T, van Os J, Myin-Germeys I (2008) Fluctuations in self-esteem and paranoia in the context of daily life. Journal of Abnormal Psychology 117: 143-153. (Pubitemid 351274095)
31. Delespaul P, deVries M, van Os J (2002) Determinants of occurrence and recovery from hallucinations in daily life. Social psychiatry and psychiatric epidemiology 37: 97-104. (Pubitemid 36097264)
32. Peerbooms O, Rutten BPF, Collip D, Lardinois M, Lataster T, et al. (2012) Evidence that interactive effects of COMT and MTHFR moderate psychotic response to environmental stress. Acta psychiatrica Scandinavica 125: 247-256.
33. van Os J, Delespaul P, Wigman J, Myin-Germeys I, Wichers M (2013) Beyond DSM and ICD: introducing "precision diagnosis" for psychiatry using momentary assessment technology. World psychiatry: official journal of the World Psychiatric Association 12: 113-117.
34. Myin-Germeys I, Krabbendam L, Jolles J, Delespaul PA, van Os J (2002) Are cognitive impairments associated with sensitivity to stress in schizophrenia? An experience sampling study. The American journal of psychiatry 159: 443-449. (Pubitemid 34184740)
35. Peerbooms OL, van Os J, Drukker M, Kenis G, Hoogveld L, et al. (2011) Meta-analysis of MTHFR gene variants in schizophrenia, bipolar disorder and unipolar depressive disorder: evidence for a common genetic vulnerability? Brain, behavior, and immunity 25: 1530-1543.
36. Edlund CK, Lee WH, Li D, Van Den Berg DJ, Conti DV (2008) Snagger: a user-friendly program for incorporating additional information for tagSNP selection. BMC bioinformatics 9: 174.
37. Li J, Ji L (2005) Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity 95: 221-227. (Pubitemid 43093236)
38. Ober C, Vercelli D (2011) Gene-environment interactions in human disease: nuisance or opportunity? Trends in genetics: TIG 27: 107-115.
39. LaPlant Q, Vialou V, Covington HE III, Dumitriu D, Feng J, et al. (2010) Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nature neuroscience 13: 1137-1143.
40. Chen T, Ueda Y, Xie S, Li E (2002) A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation. The Journal of biological chemistry 277: 38746-38754. (Pubitemid 35154737)
41. Weisenberger DJ, Velicescu M, Preciado-Lopez MA, Gonzales FA, Tsai YC, et al. (2002) Identification and characterization of alternatively spliced variants of DNA methyltransferase 3a in mammalian cells. Gene 298: 91-99. (Pubitemid 35284266)
42. Flicek P, Amode MR, Barrell D, Beal K, Billis K, et al. (2014) Ensembl 2014. Nucleic Acids Research 42: D749-D755.
43. Lister R, Mukamel EA, Nery JR, Urich M, Puddifoot CA, et al. (2013) Global epigenomic reconfiguration during mammalian brain development. Science 341: 1237905.
44. Gross JJ (1998) Antecedent- and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. Journal of personality and social psychology 74: 224-237.
45. Smith ZD, Meissner A (2013) DNA methylation: roles in mammalian development. Nature reviews Genetics 14: 204-220.
46. Hunter DJ (2005) Gene-environment interactions in human diseases. Nature reviews Genetics 6: 287-298.
47. Moffitt TE, Caspi A, Rutter M (2005) Strategy for investigating interactions between measured genes and measured environments. Archives of general psychiatry 62: 473-481. (Pubitemid 40637222)
48. Lin PI, Vance JM, Pericak-Vance MA, Martin ER (2007) No gene is an island: The flip-flop phenomenon. American journal of human genetics 80: 531-538.
49. Lin PI (2007) No gene is an island: The flip-flop phenomenon (vol 80, pg 531, 2007). American journal of human genetics 80: 1002-1002.