메뉴 건너뛰기




Volumn 239, Issue 6, 2014, Pages 697-706

Decreased glutathione and elevated hair mercury levels are associated with nutritional deficiency-based autism in Oman

Author keywords

Cobalamin; epigenetic; folic acid; homocysteine thiolactone; methionine synthase; neurodevelopment

Indexed keywords

CYANOCOBALAMIN; CYSTATHIONINE; CYSTEINE; CYSTINE; FOLIC ACID; GLUTATHIONE; GLUTATHIONE DISULFIDE; HOMOCYSTEINE; HOMOCYSTINE; MERCURY; METHIONINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; THIOL; 5 METHYLTETRAHYDROFOLATE HOMOCYSTEINE METHYLTRANSFERASE;

EID: 84903388489     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370214527900     Document Type: Article
Times cited : (42)

References (84)
  • 1
    • 84859394070 scopus 로고    scopus 로고
    • Prevalence of autism spectrum disorders--Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008
    • Prevalence of autism spectrum disorders--Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008.MMWR Surveill Summ. 2012;61:1-19.
    • (2012) MMWR Surveill Summ , vol.61 , pp. 1-19
  • 2
    • 84903396742 scopus 로고
    • Autistic disorder, PDD-NOS, Asperger's disorder, Rett's disorder, and childhood disintegrative disorder
    • American Psychiatric Association In: Frances A, First M (eds) 4th ed. (DSM-IV). Washington, DC: American Psychiatric Publishing
    • American Psychiatric Association. Autistic disorder, PDD-NOS, Asperger's disorder, Rett's disorder, and childhood disintegrative disorder. In: Frances A, First M (eds) Diagnostic and statistical manual of mental disorders. 4th ed. (DSM-IV). Washington, DC: American Psychiatric Publishing; 1994.
    • (1994) Diagnostic and statistical manual of mental disorders
  • 3
    • 21644437362 scopus 로고    scopus 로고
    • Spontaneous mucosal lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms: mucosal immune activation and reduced counter regulatory interleukin-10
    • Ashwood P,Anthony A,Torrente F,Wakefield AJ.Spontaneous mucosal lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms: mucosal immune activation and reduced counter regulatory interleukin-10.J Clin Immunol. 2004;24:664-73.
    • (2004) J Clin Immunol , vol.24 , pp. 664-673
    • Ashwood, P.1    Anthony, A.2    Torrente, F.3    Wakefield, A.J.4
  • 6
    • 77949343048 scopus 로고    scopus 로고
    • The immune system's role in the biology of autism
    • Goines P,Van de Water J.The immune system's role in the biology of autism.Curr Opin Neurol. 2010;23:111-7.
    • (2010) Curr Opin Neurol , vol.23 , pp. 111-117
    • Goines, P.1    van de Water, J.2
  • 7
    • 77649263615 scopus 로고    scopus 로고
    • Frequency of CD4+CD25 high regulatory T cells in the peripheral blood of Egyptian children with autism
    • Mostafa GA,Al Shehab A,Fouad NR.Frequency of CD4+CD25 high regulatory T cells in the peripheral blood of Egyptian children with autism.J Child Neurol. 2010;25:328-35.
    • (2010) J Child Neurol , vol.25 , pp. 328-335
    • Mostafa, G.A.1    Al Shehab, A.2    Fouad, N.R.3
  • 8
    • 80052864423 scopus 로고    scopus 로고
    • Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes
    • Jyonouchi H,Geng L,Streck DL,Toruner GA.Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes.J Neuroimmunol. 2011;238:73-80.
    • (2011) J Neuroimmunol , vol.238 , pp. 73-80
    • Jyonouchi, H.1    Geng, L.2    Streck, D.L.3    Toruner, G.A.4
  • 9
    • 84857190395 scopus 로고    scopus 로고
    • The role of immune dysfunction in the pathophysiology of autism
    • Onore C,Careaga M,Ashwood P.The role of immune dysfunction in the pathophysiology of autism.Brain Behav Immun. 2012;26:383-92.
    • (2012) Brain Behav Immun , vol.26 , pp. 383-392
    • Onore, C.1    Careaga, M.2    Ashwood, P.3
  • 10
    • 84859005372 scopus 로고    scopus 로고
    • A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures
    • Rossignol DA,Frye RE.A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures.Mol Psychiatry. 2012;17:389-401.
    • (2012) Mol Psychiatry , vol.17 , pp. 389-401
    • Rossignol, D.A.1    Frye, R.E.2
  • 16
    • 77953545864 scopus 로고    scopus 로고
    • The role of MeCP2 in brain development and neurodevelopmental disorders
    • Gonzales ML,LaSalle JM.The role of MeCP2 in brain development and neurodevelopmental disorders.Curr Psychiatry Rep. 2010;12:127-34.
    • (2010) Curr Psychiatry Rep , vol.12 , pp. 127-134
    • Gonzales, M.L.1    LaSalle, J.M.2
  • 18
    • 77958500315 scopus 로고    scopus 로고
    • Genomic copy number variation in disorders of cognitive development
    • Morrow EM.Genomic copy number variation in disorders of cognitive development.J Am Acad Child Adolesc Psychiatry. 2010;49:1091-104.
    • (2010) J Am Acad Child Adolesc Psychiatry , vol.49 , pp. 1091-1104
    • Morrow, E.M.1
  • 19
    • 84877695008 scopus 로고    scopus 로고
    • Environmental factors in autism
    • Grabrucker AM.Environmental factors in autism.Front Psychiatry. 2012;3:118-118.
    • (2012) Front Psychiatry , vol.3 , pp. 118
    • Grabrucker, A.M.1
  • 20
    • 84864149353 scopus 로고    scopus 로고
    • A research strategy to discover the environmental causes of autism and neurodevelopmental disabilities
    • Landrigan PJ,Lambertini L,Birnbaum LS.A research strategy to discover the environmental causes of autism and neurodevelopmental disabilities.Environ Health Perspect. 2012;120:a258-60.
    • (2012) Environ Health Perspect , vol.120
    • Landrigan, P.J.1    Lambertini, L.2    Birnbaum, L.S.3
  • 21
    • 84864120951 scopus 로고    scopus 로고
    • Tipping the balance of autism risk: potential mechanisms linking pesticides and autism
    • Shelton JF,Hertz-Picciotto I,Pessah IN.Tipping the balance of autism risk: potential mechanisms linking pesticides and autism.Environ Health Perspect. 2012;120:944-51.
    • (2012) Environ Health Perspect , vol.120 , pp. 944-951
    • Shelton, J.F.1    Hertz-Picciotto, I.2    Pessah, I.N.3
  • 22
    • 37849037738 scopus 로고    scopus 로고
    • How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
    • Deth R,Muratore C,Benzecry J,Power-Charnitsky V-A,Waly M.How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis.Neurotoxicology. 2008;29:190-201.
    • (2008) Neurotoxicology , vol.29 , pp. 190-201
    • Deth, R.1    Muratore, C.2    Benzecry, J.3    Power-Charnitsky, V.-A.4    Waly, M.5
  • 24
    • 79960118297 scopus 로고    scopus 로고
    • A genomic point-of-view on environmental factors influencing the human brain methylome
    • LaSalle JM.A genomic point-of-view on environmental factors influencing the human brain methylome.Epigenetics. 2011;6:862-9.
    • (2011) Epigenetics , vol.6 , pp. 862-869
    • LaSalle, J.M.1
  • 26
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir RE,Van den Veyver IB,Wan M,Tran CQ,Francke U,Zoghbi HY.Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2.Nat Genet. 1999;23:185-8.
    • (1999) Nat Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 27
    • 15544382113 scopus 로고    scopus 로고
    • Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples
    • Thatcher KN,Peddada S,Yasui DH,Lasalle JM.Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples.Hum Mol Genet. 2005;14:785-97.
    • (2005) Hum Mol Genet , vol.14 , pp. 785-797
    • Thatcher, K.N.1    Peddada, S.2    Yasui, D.H.3    Lasalle, J.M.4
  • 30
  • 31
    • 56349142882 scopus 로고    scopus 로고
    • Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism
    • James SJ,Melnyk S,Jernigan S,Hubanks A,Rose S,Gaylor DW.Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism.J Autism Dev Disord. 2008;38:1966-75.
    • (2008) J Autism Dev Disord , vol.38 , pp. 1966-1975
    • James, S.J.1    Melnyk, S.2    Jernigan, S.3    Hubanks, A.4    Rose, S.5    Gaylor, D.W.6
  • 33
    • 67349230153 scopus 로고    scopus 로고
    • Metabolic biomarkers related to oxidative stress and antioxidant status in Saudi autistic children
    • Al-Gadani Y,El-Ansary A,Attas O,Al-Ayadhi L.Metabolic biomarkers related to oxidative stress and antioxidant status in Saudi autistic children.Clin Biochem. 2009;42:1032-40.
    • (2009) Clin Biochem , vol.42 , pp. 1032-1040
    • Al-Gadani, Y.1    El-Ansary, A.2    Attas, O.3    Al-Ayadhi, L.4
  • 38
    • 84863011800 scopus 로고    scopus 로고
    • Nutritional influences on epigenetics and age-related disease
    • Park LK,Friso S,Choi SW.Nutritional influences on epigenetics and age-related disease.Proc Nutr Soc. 2012;71:75-83.
    • (2012) Proc Nutr Soc , vol.71 , pp. 75-83
    • Park, L.K.1    Friso, S.2    Choi, S.W.3
  • 39
    • 84864010293 scopus 로고    scopus 로고
    • Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation
    • Anderson OS,Sant KE,Dolinoy DC.Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation.J Nutr Biochem. 2012;23:853-9.
    • (2012) J Nutr Biochem , vol.23 , pp. 853-859
    • Anderson, O.S.1    Sant, K.E.2    Dolinoy, D.C.3
  • 40
    • 83755220033 scopus 로고    scopus 로고
    • Maternal micronutrients (folic acid and vitamin B(12)) and omega 3 fatty acids: implications for neurodevelopmental risk in the rat offspring
    • Roy S,Kale A,Dangat K,Sable P,Kulkarni A,Joshi S.Maternal micronutrients (folic acid and vitamin B(12)) and omega 3 fatty acids: implications for neurodevelopmental risk in the rat offspring.Brain Dev. 2012;34:64-71.
    • (2012) Brain Dev , vol.34 , pp. 64-71
    • Roy, S.1    Kale, A.2    Dangat, K.3    Sable, P.4    Kulkarni, A.5    Joshi, S.6
  • 44
    • 80052665221 scopus 로고    scopus 로고
    • Chemical biology of homocysteine thiolactone and related metabolites
    • Jakubowski H,Głowacki R.Chemical biology of homocysteine thiolactone and related metabolites.Adv Clin Chem. 2011;55:81-103.
    • (2011) Adv Clin Chem , vol.55 , pp. 81-103
    • Jakubowski, H.1    Głowacki, R.2
  • 46
    • 84875691670 scopus 로고    scopus 로고
    • Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury
    • Farina M,Avila DS,da Rocha JB,Aschner M.Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury.Neurochem Int. 2013;62:575-94.
    • (2013) Neurochem Int , vol.62 , pp. 575-594
    • Farina, M.1    Avila, D.S.2    da Rocha, J.B.3    Aschner, M.4
  • 47
    • 45549099735 scopus 로고    scopus 로고
    • Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity
    • Carvalho CM,Chew EH,Hashemy SI,Lu J,Holmgren A.Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity.J Biol Chem. 2008;283:11913-23.
    • (2008) J Biol Chem , vol.283 , pp. 11913-11923
    • Carvalho, C.M.1    Chew, E.H.2    Hashemy, S.I.3    Lu, J.4    Holmgren, A.5
  • 49
    • 79960670867 scopus 로고    scopus 로고
    • The plausibility of a role for mercury in the etiology of autism: a cellular perspective
    • Garrecht M,Austin DW.The plausibility of a role for mercury in the etiology of autism: a cellular perspective.Toxicol Environ Chem. 2011;93:1251-1273.
    • (2011) Toxicol Environ Chem , vol.93 , pp. 1251-1273
    • Garrecht, M.1    Austin, D.W.2
  • 50
    • 70350645116 scopus 로고    scopus 로고
    • Chemical methods for the detection of protein N-homocysteinylation via selective reactions with aldehydes
    • Zang T,Dai S,Chen D,Lee BW,Liu S,Karger BL,Zhou ZS.Chemical methods for the detection of protein N-homocysteinylation via selective reactions with aldehydes.Anal Chem. 2009;81:9065-71.
    • (2009) Anal Chem , vol.81 , pp. 9065-9071
    • Zang, T.1    Dai, S.2    Chen, D.3    Lee, B.W.4    Liu, S.5    Karger, B.L.6    Zhou, Z.S.7
  • 51
    • 21744453472 scopus 로고    scopus 로고
    • Toxic trace elements in the hair of children with autism
    • Fido A,Al-Saad S.Toxic trace elements in the hair of children with autism.Autism. 2005;9:290-8.
    • (2005) Autism , vol.9 , pp. 290-298
    • Fido, A.1    Al-Saad, S.2
  • 52
    • 0030885191 scopus 로고    scopus 로고
    • Aminoacyl thioester chemistry of class II aminoacyl-tRNA synthetases
    • Jakubowski H.Aminoacyl thioester chemistry of class II aminoacyl-tRNA synthetases.Biochemistry. 1997;36:11077-85.
    • (1997) Biochemistry , vol.36 , pp. 11077-11085
    • Jakubowski, H.1
  • 53
    • 33645238117 scopus 로고    scopus 로고
    • High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism
    • Paşca SP,Nemeş B,Vlase L,Gagyi CE,Dronca E,Miu AC,Dronca M.High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism.Life Sci. 2006;78:2244-8.
    • (2006) Life Sci , vol.78 , pp. 2244-2248
    • Paşca, S.P.1    Nemeş, B.2    Vlase, L.3    Gagyi, C.E.4    Dronca, E.5    Miu, A.C.6    Dronca, M.7
  • 55
    • 0035371184 scopus 로고    scopus 로고
    • Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
    • Schafer FQ,Buettner GR.Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple.Free Radic Biol Med. 2001;30:1191-212.
    • (2001) Free Radic Biol Med , vol.30 , pp. 1191-1212
    • Schafer, F.Q.1    Buettner, G.R.2
  • 57
    • 84864360468 scopus 로고    scopus 로고
    • Brain region-specific glutathione redox imbalance in autism
    • Chauhan A,Audhya T,Chauhan V.Brain region-specific glutathione redox imbalance in autism.Neurochem Res. 2012;37:1681-9.
    • (2012) Neurochem Res , vol.37 , pp. 1681-1689
    • Chauhan, A.1    Audhya, T.2    Chauhan, V.3
  • 58
    • 84863736932 scopus 로고    scopus 로고
    • Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain
    • Rose S,Melnyk S,Pavliv O,Bai S,Nick TG,Frye RE,James SJ.Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain.Transl Psychiatry. 2012;2:e134-e134.
    • (2012) Transl Psychiatry , vol.2
    • Rose, S.1    Melnyk, S.2    Pavliv, O.3    Bai, S.4    Nick, T.G.5    Frye, R.E.6    James, S.J.7
  • 59
    • 84881514848 scopus 로고    scopus 로고
    • Impaired synthesis and antioxidant defense of glutathione in the cerebellum of autistic subjects: Alterations in the activities and protein expression of glutathione-related enzymes
    • Gu F,Chauhan V,Chauhan A.Impaired synthesis and antioxidant defense of glutathione in the cerebellum of autistic subjects: Alterations in the activities and protein expression of glutathione-related enzymes.Free Radic Biol Med. 2013;65C:488-96.
    • (2013) Free Radic Biol Med , vol.65 C , pp. 488-496
    • Gu, F.1    Chauhan, V.2    Chauhan, A.3
  • 60
    • 0030990682 scopus 로고    scopus 로고
    • Structure-based perspectives on B12-dependent enzymes
    • Ludwig ML,Matthews RG.Structure-based perspectives on B12-dependent enzymes.Annu Rev Biochem. 1997;66:269-313.
    • (1997) Annu Rev Biochem , vol.66 , pp. 269-313
    • Ludwig, M.L.1    Matthews, R.G.2
  • 61
    • 75049083298 scopus 로고    scopus 로고
    • Genome-scale approaches to the epigenetics of common human disease
    • Feinberg AP.Genome-scale approaches to the epigenetics of common human disease.Virchows Arch. 2010;456:13-21.
    • (2010) Virchows Arch , vol.456 , pp. 13-21
    • Feinberg, A.P.1
  • 62
    • 84880642710 scopus 로고    scopus 로고
    • The epigenetic switches for neural development and psychiatric disorders
    • Lv J,Xin Y,Zhou W,Qiu Z.The epigenetic switches for neural development and psychiatric disorders.J Genet Genomics. 2013;40:339-46.
    • (2013) J Genet Genomics , vol.40 , pp. 339-346
    • Lv, J.1    Xin, Y.2    Zhou, W.3    Qiu, Z.4
  • 64
    • 84871563384 scopus 로고    scopus 로고
    • MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
    • Mellén M,Ayata P,Dewell S,Kriaucionis S,Heintz N.MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.Cell. 2012;151:1417-30.
    • (2012) Cell , vol.151 , pp. 1417-1430
    • Mellén, M.1    Ayata, P.2    Dewell, S.3    Kriaucionis, S.4    Heintz, N.5
  • 67
    • 84897111264 scopus 로고    scopus 로고
    • Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits
    • DOI: 10.1038/mp.2013.41. [Epub ahead of print]
    • Wong CC, Meaburn EL, Ronald A, Price TS, Jeffries AR, Schalkwyk LC, Plomin R, Mill J. Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits. Mol Psychiatry 2013. DOI: 10.1038/mp.2013.41. [Epub ahead of print].
    • (2013) Mol Psychiatry
    • Wong, C.C.1    Meaburn, E.L.2    Ronald, A.3    Price, T.S.4    Jeffries, A.R.5    Schalkwyk, L.C.6    Plomin, R.7    Mill, J.8
  • 69
    • 2442641844 scopus 로고    scopus 로고
    • Cross-talk between Cys34 and lysine residues in human serum albumin revealed by N-homocysteinylation
    • Glowacki R,Jakubowski H.Cross-talk between Cys34 and lysine residues in human serum albumin revealed by N-homocysteinylation.J Biol Chem. 2004;279:10864-71.
    • (2004) J Biol Chem , vol.279 , pp. 10864-10871
    • Glowacki, R.1    Jakubowski, H.2
  • 70
    • 33747038067 scopus 로고    scopus 로고
    • Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus
    • Lakshman MR,Gottipati CS,Narasimhan SJ,Munoz J,Marmillot P,Nylen ES.Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus.Metabolism. 2006;55:1201-6.
    • (2006) Metabolism , vol.55 , pp. 1201-1206
    • Lakshman, M.R.1    Gottipati, C.S.2    Narasimhan, S.J.3    Munoz, J.4    Marmillot, P.5    Nylen, E.S.6
  • 71
    • 36848998882 scopus 로고    scopus 로고
    • The molecular basis of homocysteine thiolactone-mediated vascular disease
    • Jakubowski H.The molecular basis of homocysteine thiolactone-mediated vascular disease.Clin Chem Lab Med. 2007;45:1704-16.
    • (2007) Clin Chem Lab Med , vol.45 , pp. 1704-1716
    • Jakubowski, H.1
  • 73
    • 45549099735 scopus 로고    scopus 로고
    • Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity
    • Carvalho CM,Chew EH,Hashemy SI,Lu J,Holmgren A.Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity.J Biol Chem. 2008;283:11913-23.
    • (2008) J Biol Chem , vol.283 , pp. 11913-11923
    • Carvalho, C.M.1    Chew, E.H.2    Hashemy, S.I.3    Lu, J.4    Holmgren, A.5
  • 75
    • 84884736042 scopus 로고    scopus 로고
    • Selenium homeostasis and antioxidant selenoproteins in brain: Implications for disorders in the central nervous system
    • Steinbrenner H,Sies H.Selenium homeostasis and antioxidant selenoproteins in brain: Implications for disorders in the central nervous system.Arch Biochem Biophys. 2013;536:152-7.
    • (2013) Arch Biochem Biophys , vol.536 , pp. 152-157
    • Steinbrenner, H.1    Sies, H.2
  • 76
    • 84873921635 scopus 로고    scopus 로고
    • Human exposure and health effects of inorganic and elemental mercury
    • Park JD,Zheng W.Human exposure and health effects of inorganic and elemental mercury.J Prev Med Public Health. 2012;45:344-52.
    • (2012) J Prev Med Public Health , vol.45 , pp. 344-352
    • Park, J.D.1    Zheng, W.2
  • 78
    • 84875037540 scopus 로고    scopus 로고
    • Mercury biomarkers and DNA methylation among Michigan dental professionals
    • Goodrich JM,Basu N,Franzblau A,Dolinoy DC.Mercury biomarkers and DNA methylation among Michigan dental professionals.Environ Mol Mutagen. 2013;54:195-203.
    • (2013) Environ Mol Mutagen , vol.54 , pp. 195-203
    • Goodrich, J.M.1    Basu, N.2    Franzblau, A.3    Dolinoy, D.C.4
  • 80
    • 0041694381 scopus 로고    scopus 로고
    • Reduced levels of mercury in first baby haircuts of autistic children
    • Holmes AS,Blaxill MF,Haley BE.Reduced levels of mercury in first baby haircuts of autistic children.Int J Toxicol. 2003;22:277-85.
    • (2003) Int J Toxicol , vol.22 , pp. 277-285
    • Holmes, A.S.1    Blaxill, M.F.2    Haley, B.E.3
  • 82
    • 23044461460 scopus 로고    scopus 로고
    • Heavy metals and trace elements in hair samples of autistic children in central Saudi Arabia
    • Al-Ayadhi LY.Heavy metals and trace elements in hair samples of autistic children in central Saudi Arabia.Neurosciences (Riyadh). 2005;10:213-18.
    • (2005) Neurosciences (Riyadh) , vol.10 , pp. 213-218
    • Al-Ayadhi, L.Y.1
  • 83
    • 84871641182 scopus 로고    scopus 로고
    • Toxic metals and essential elements in hair and severity of symptoms among children with autism
    • Blaurock-Busch E,Amin OR,Dessoki HH,Rabah T.Toxic metals and essential elements in hair and severity of symptoms among children with autism.Maedica (Buchar). 2012;7:38-48.
    • (2012) Maedica (Buchar) , vol.7 , pp. 38-48
    • Blaurock-Busch, E.1    Amin, O.R.2    Dessoki, H.H.3    Rabah, T.4
  • 84
    • 84873693741 scopus 로고    scopus 로고
    • Estimation of autistic children by metallomics analysis
    • Yasuda H,Yasuda Y,Tsutsui T.Estimation of autistic children by metallomics analysis.Sci Rep. 2013;3:1199-1199.
    • (2013) Sci Rep , vol.3 , pp. 1199
    • Yasuda, H.1    Yasuda, Y.2    Tsutsui, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.