The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status

Molecular Microbiology

Volumn 93, Issue 1, 2014, Pages 80-97

  Yau, Wai Lok ^a,c,h   Pescher, Pascale ^a,h   Macdonald, Andrea ^a,c   Hem, Sonia ^a,d   Zander, Dorothea ^a,c   Retzlaff, Silke ^a,c,f   Blisnick, Thierry ^a,b   Rotureau, Brice ^a,b   Rosenqvist, Heidi ^a,e,g   Wiese, Martin ^a,e   Bastin, Philippe ^a,b   Clos, Joachim ^a,c   Späth, Gerald F ^a,h  

^a CNRS   (France)

^b Unité de Biologie Cellulaire des Trypanosomes   (France)

^c BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^d INRA   (France)

^e UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^f Altona Diagnostics   (Germany)

^g NOVO NORDISK A S   (Denmark)

^h Unité de Parasitologie Moléculaire et Signalisation   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; CYCLOPHILIN; LEISHMANIA DONOVANI CHAPERONE CYCLOPHILIN 40; MESSENGER RNA; PROTEIN A2; TUBULIN; UNCLASSIFIED DRUG; PROTOZOAL PROTEIN;

3' UNTRANSLATED REGION; AMASTIGOTE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; AXENIC AMASTIGOTE; CELL MOTILITY; CELL SHAPE; CELL ULTRASTRUCTURE; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; ENVIRONMENTAL STRESS; GENETIC COMPLEMENTATION; GENETIC CONSERVATION; HUMAN; IN VITRO STUDY; INTRACELLULAR INFECTION; LEISHMANIASIS; LOSS OF FUNCTION MUTATION; MACROPHAGE; MOLECULAR CLONING; MORPHOGENESIS; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PARASITE SURVIVAL; PARASITE VIABILITY; PHENOTYPE; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION; ANIMAL; C57BL MOUSE; CYTOSKELETON; GENETICS; LEISHMANIA DONOVANI; METABOLISM; PARASITOLOGY; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; ULTRASTRUCTURE; VISCERAL LEISHMANIASIS;

ANIMALS; CYCLOPHILINS; CYTOSKELETON; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MACROPHAGES; MICE; MICE, INBRED C57BL; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTOZOAN PROTEINS; STRESS, PHYSIOLOGICAL;

EID: 84903388345     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12639     Document Type: Article

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