Oral intake of chicoric acid reduces acute alcohol-induced hepatic steatosis in mice

Nutrition

Volumn 30, Issue 7-8, 2014, Pages 882-889

  Landmann, Marianne ^a   Kanuri, Giridhar ^a   Spruss, Astrid ^b   Stahl, Carolin ^b   Bergheim, Ina ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Alcohol; Chicoric acid; Endotoxin; Steatosis

Indexed keywords

4 HYDROXYNONENAL; CICHORIC ACID; GLYCOPROTEIN P 15095; I KAPPA B; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; OCCLUDIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE B; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ALCOHOL; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CAFFEIC ACID DERIVATIVE; PLANT EXTRACT; SUCCINIC ACID DERIVATIVE;

ADH1 GENE; ALCOHOLIC FATTY LIVER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYP2 E1 GENE; DISEASE ASSOCIATION; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FEMALE; GENE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; KUPFFER CELL; LIPID STORAGE; LIVER PROTECTION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CHEMISTRY; CHICORY; DRUG EFFECTS; ECHINACEA; FATTY LIVER, ALCOHOLIC; GENETICS; LIVER; METABOLISM; ORAL DRUG ADMINISTRATION; PHYTOTHERAPY;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CAFFEIC ACIDS; CHICORY; ECHINACEA; ETHANOL; FATTY LIVER, ALCOHOLIC; FEMALE; IN VITRO TECHNIQUES; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LIVER; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; PHYTOTHERAPY; PLANT EXTRACTS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RNA, MESSENGER; SUCCINATES; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84903383373     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2013.11.015     Document Type: Article

References (27)

1. Harrison S.A., Diehl A.M. Fat and the liver-a molecular overview. Semin Gastrointest Dis 2002, 13:3-16.
2. Bergheim I., Guo L., Davis M.A., Lambert J.C., Beier J.I., Duveau I., et al. Metformin prevents alcohol-induced liver injury in the mouse: critical role of plasminogen activator inhibitor-1. Gastroenterology 2006, 130:2099-2112.
3. Adachi Y., Moore L.E., Bradford B.U., Gao W., Thurman R.G. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995, 108:218-224.
4. Bode C., Kugler V., Bode J.C. Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess. J Hepatol 1987, 4:8-14.
5. Thurman R.G., Bradford B.U., Iimuro Y., Knecht K.T., Arteel G.E., Yin M., et al. The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury. J Gastroenterol Hepatol 1998, 13(Suppl):S39-S50.
6. McKim S.E., Gabele E., Isayama F., Lambert J.C., Tucker L.M., Wheeler M.D., et al. Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice. Gastroenterology 2003, 125:1834-1844.
7. Venkatraman A., Shiva S., Wigley A., Ulasova E., Chhieng D., Bailey S.M., et al. The role of iNOS in alcohol-dependent hepatotoxicity and mitochondrial dysfunction in mice. Hepatology 2004, 40:565-573.
8. Louvet A., Teixeira-Clerc F., Chobert M.N., Deveaux V., Pavoine C., Zimmer A., et al. Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice. Hepatology 2011, 54:1217-1226.
9. Facino R.M., Carini M., Aldini G., Saibene L., Pietta P., Mauri P. Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: a potential use of Echinacea extracts in the prevention of skin photodamage. Planta Med 1995, 61:510-514.
10. Juskiewicz J., Zdunczyk Z., Zary-Sikorska E., Krol B., Milala J., Jurgonski A. Effect of the dietary polyphenolic fraction of chicory root, peel, seed and leaf extracts on caecal fermentation and blood parameters in rats fed diets containing prebiotic fructans. Br J Nutr 2011, 105:710-720.
11. Dalby-Brown L., Barsett H., Landbo A.K., Meyer A.S., Molgaard P. Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on invitro oxidation of human low-density lipoproteins. J Agric Food Chem 2005, 53:9413-9423.
12. Kour K., Bani S. Chicoric acid regulates behavioral and biochemical alterations induced by chronic stress in experimental Swiss albino mice. Pharmacol Biochem Behav 2011, 99:342-348.
13. Reinke R.A., Lee D.J., McDougall B.R., King P.J., Victoria J., Mao Y., et al. L-chicoric acid inhibits human immunodeficiency virus type 1 integration invivo and is a noncompetitive but reversible inhibitor of HIV-1 integrase invitro. Virology 2004, 326:203-219.
14. Park C.M., Jin K.S., Lee Y.W., Song Y.S. Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3 K-Akt pathway and impairment of NF-kappaB translocation in LPS stimulated RAW 264.7 cells. Eur J Pharmacol 2011, 660:454-459.
15. Wagnerberger S., Fiederlein L., Kanuri G., Stahl C., Millonig G., Mueller S., et al. Sex-specific differences in the development of acute alcohol-induced liver steatosis in mice. Alcohol Alcohol 2013, 48:648-656.
16. Kanuri G., Weber S., Volynets V., Spruss A., Bischoff S.C., Bergheim I. Cinnamon extract protects against acute alcohol-induced liver steatosis in mice. J Nutr 2009, 139:482-487.
17. Bonnichsen R., Lundgren G. Comparison of the ADH and the Widmark procedures in forensic chemistry for determinating alcohol. Acta Pharmacol Toxicol (Copenh) 1957, 13:256-266.
18. Kanuri G., Spruss A., Wagnerberger S., Bischoff S.C., Bergheim I. Fructose-induced steatosis in mice: role of plasminogen activator inhibitor-1, microsomal triglyceride transfer protein and NKT cells. Lab Invest 2011, 91:885-895.
19. Bergheim I., Weber S., Vos M., Kramer S., Volynets V., Kaserouni S., et al. Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin. J Hepatol 2008, 48:983-992.
20. Arteel G.E. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterology 2003, 124:778-790.
21. Rivera C.A., Bradford B.U., Seabra V., Thurman R.G. Role of endotoxin in the hypermetabolic state after acute ethanol exposure. Am J Physiol 1998, 275(6 Pt 1):G1252-G1258.
22. Nagy L.E. Molecular aspects of alcohol metabolism: transcription factors involved in early ethanol-induced liver injury. Annu Rev Nutr 2004, 24:55-78.
23. Arteel G.E. New role of plasminogen activator inhibitor-1 in alcohol-induced liver injury. J Gastroenterol Hepatol 2008, 23(Suppl 1):S54-S59.
24. Spruss A., Kanuri G., Stahl C., Bischoff S.C., Bergheim I. Metformin protects against the development of fructose-induced steatosis in mice: role of the intestinal barrier function. Lab Invest 2012, 92:1020-1032.
25. Odegaard J.I., Ricardo-Gonzalez R.R., Goforth M.H., Morel C.R., Subramanian V., Mukundan L., et al. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 2007, 447:1116-1120.
26. Wagnerberger S., Spruss A., Kanuri G., Stahl C., Schroder M., Vetter W., et al. Lactobaccilus casei Shirota protects from fructose-induced liver steatosis: a mouse model. J Nutr Biochem 2013, 24:531-538.
27. Bel-Rhlid R., Page-Zoerkler N., Fumeaux R., Ho-Dac T., Chuat J.Y., Sauvageat J.L., et al. Hydrolysis of chicoric and caftaric acids with esterases and Lactobacillus johnsonii inVitro and in a gastrointestinal model. J Agric Food Chem 2012, 60:9236-9241.