Increased protein kinase C gamma activity induces Purkinje cell pathology in a mouse model of spinocerebellar ataxia 14

Neurobiology of Disease

Volumn 70, Issue , 2014, Pages 1-11

  Ji, Jingmin ^a   Hassler, Melanie L ^a   Shimobayashi, Etsuko ^a   Paka, Nagendher ^a   Streit, Raphael ^a   Kapfhammer, Josef P ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Protein kinase C gamma; Purkinje cell dendritic development; Spinocerebellar ataxia type 14; Transgenic mouse model

Indexed keywords

PROTEIN KINASE C GAMMA; PROTEIN KINASE C;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CELLULAR DISTRIBUTION; CEREBELLAR ATAXIA; CEREBELLUM ATROPHY; IN VIVO STUDY; JUVENILE ANIMAL; MOUSE; MUTATIONAL ANALYSIS; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PURKINJE CELL; ROTAROD TEST; SPINOCEREBELLAR ATAXIA 14; SPINOCEREBELLAR DEGENERATION; TRANSGENIC MOUSE; WALKING; ANIMAL; CEREBELLUM; DENDRITE; DISEASE MODEL; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; MOTOR ACTIVITY; MUTATION; PATHOLOGY; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE; WESTERN BLOTTING; CELL STRUCTURE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME ACTIVITY; EXPERIMENTAL LOCOMOTOR ACTIVITY TEST; GENE EXPRESSION; SPINOCEREBELLAR DEGENERATION TYPE 14; WALKING BEAM TEST;

ANIMALS; BLOTTING, WESTERN; CEREBELLUM; DENDRITES; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOHISTOCHEMISTRY; MICE, TRANSGENIC; MOTOR ACTIVITY; MUTATION; PROTEIN KINASE C; PURKINJE CELLS; ROTAROD PERFORMANCE TEST; SPINOCEREBELLAR DEGENERATIONS; TISSUE CULTURE TECHNIQUES;

EID: 84903375433     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.06.002     Document Type: Article

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