Aging induced endoplasmic reticulum stress alters sleep and sleep homeostasis

Neurobiology of Aging

Volumn 35, Issue 6, 2014, Pages 1431-1441

  Brown, Marishka K ^a   Chan, May T ^a   Zimmerman, John E ^a   Pack, Allan I ^a,b   Jackson, Nicholas E ^a   Naidoo, Nirinjini ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

4 phenylbutyrate; Aging; Chaperone; Sleep; Sleep loss deprivation; Unfolded protein response

Indexed keywords

4 PHENYLBUTYRIC ACID; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; PROTEIN IRE1; PROTEIN KINASE RNA LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN SERINE THREONINE KINASE; TUNICAMYCIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; 4-PHENYLBUTYRIC ACID; ARYLBUTYRIC ACID DERIVATIVE; CHAPERONE; DNA BINDING PROTEIN; INITIATION FACTOR;

ACUTE DRUG ADMINISTRATION; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DROSOPHILA MELANOGASTER; ENDOPLASMIC RETICULUM STRESS; FEMALE; HOMEOSTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; SLEEP; SLEEP DEPRIVATION; SLEEP HOMEOSTASIS; SLEEP PATTERN; SLEEP QUALITY; SLEEP TIME; UNFOLDED PROTEIN RESPONSE; UPREGULATION; WAKEFULNESS; ANIMAL; ANIMAL BEHAVIOR; DRUG EFFECTS; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN UNFOLDING;

AGING; ANIMALS; BEHAVIOR, ANIMAL; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; MOLECULAR CHAPERONES; PEPTIDE INITIATION FACTORS; PHENYLBUTYRATES; PROTEIN UNFOLDING; SIGNAL TRANSDUCTION; SLEEP; SLEEP DEPRIVATION; UP-REGULATION;

EID: 84903363772     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.12.005     Document Type: Article

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