Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathway

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Yoshida, Yohko ^a   Hayashi, Yuka ^a   Suda, Masayoshi ^a   Tateno, Kaoru ^b   Okada, Sho ^b   Moriya, Junji ^b   Yokoyama, Masataka ^b   Nojima, Aika ^b   Yamashita, Masakatsu ^c   Kobayashi, Yoshio ^b   Shimizu, Ippei ^a   Minamino, Tohru ^a,d  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KAZUSA DNA RESEARCH INSTITUTE   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITOR OF DIFFERENTIATION 1; JAGGED1; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; NOTCH RECEPTOR; PROTEIN P16; CALCIUM BINDING PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; ID1 PROTEIN, HUMAN; MEMBRANE PROTEIN; NOTCH1 RECEPTOR; PROTEIN KINASE INHIBITOR; SERRATE PROTEINS; SIGNAL PEPTIDE;

ANIMAL TISSUE; ARTICLE; CELL AGING; CELL DIVISION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIFESPAN; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SENESCENCE; UPREGULATION; VASCULAR ENDOTHELIUM; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; PHENOTYPE; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; CALCIUM-BINDING PROTEINS; CELL AGING; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DUAL SPECIFICITY PHOSPHATASE 1; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PROTEIN KINASE INHIBITORS; PROTEOLYSIS; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84903289514     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100359     Document Type: Article

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