Notch activation induces endothelial cell senescence and pro-inflammatory response: Implication of Notch signaling in atherosclerosis

Atherosclerosis

Volumn 225, Issue 2, 2012, Pages 296-303

  Liu, Zhao Jun ^a,b   Tan, Yurong ^a   Beecham, Gary W ^a   Seo, David M ^a   Tian, Runxia ^a   Li, Yan ^a   Vazquez Padron, Roberto I ^a   Pericak Vance, Margaret ^a   Vance, Jeffery M ^a   Goldschmidt Clermont, Pascal J ^a   Livingstone, Alan S ^a   Velazquez, Omaida C ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

Author keywords

Atherosclerosis; EC senescence; Endothelial cells (EC); Notch; Vascular inflammation

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; NOTCH RECEPTOR; RANTES;

ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD SAMPLING; CELL MIGRATION; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CYTOKINE RELEASE; ENDOTHELIUM CELL; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; LEUKOCYTE; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION;

AGE FACTORS; ANIMALS; AORTA; AORTIC DISEASES; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOTTING, WESTERN; CELL AGING; CORONARY ARTERY DISEASE; CORONARY VESSELS; CYTOKINES; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; HEK293 CELLS; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; LEUKOCYTES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NIH 3T3 CELLS; PLAQUE, ATHEROSCLEROTIC; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ARRAY ANALYSIS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TRANSFECTION; UP-REGULATION;

EID: 84869500556     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.04.010     Document Type: Article

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