Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability1

Canadian Journal of Physiology and Pharmacology

Volumn 92, Issue 7, 2014, Pages 605-612

  Bharath, Leena P ^a,b   Mueller, Robert ^a   Li, Youyou ^a   Ruan, Ting ^a   Kunz, David ^a   Goodrich, Rebekah ^a   Mills, Tyler ^a   Deeter, Lance ^a   Sargsyan, Ashot ^a,b   Babu, Pon Velayutham Anandh ^a   Graham, Timothy E ^a,b   Symons, J David ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Blood flow; Exercise; Mitochondrial turnover; Mitophagy; Nutrient deprivation; Oxidant stress; Vascular

Indexed keywords

ATG3 PROTEIN, HUMAN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; UBIQUITIN CONJUGATING ENZYME;

ANIMAL; AUTOPHAGY; BOVINE; C57BL MOUSE; CALORIC RESTRICTION; CYTOLOGY; ENDOTHELIUM CELL; FEMALE; MALE; MECHANICAL STRESS; METABOLISM; PHOSPHORYLATION; VASCULAR ENDOTHELIUM;

ANIMALS; AUTOPHAGY; CALORIC RESTRICTION; CATTLE; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; MALE; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; STRESS, MECHANICAL; UBIQUITIN-CONJUGATING ENZYMES;

EID: 84903287431     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2014-0017     Document Type: Article

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