-
3
-
-
84903229101
-
Disruptions: Innovation isn't easy, especially midstream
-
April 15
-
N. Bilton, "Disruptions: Innovation isn't easy, especially midstream," New York Times, April 15, 2012.
-
(2012)
New York Times
-
-
Bilton, N.1
-
4
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
S. B. Prusiner, "Novel proteinaceous infectious particles cause scrapie," Science 216: 136-44 (1982).
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
5
-
-
84862620376
-
A unifying role for prions in neurodegenerative diseases
-
S. B. Prusiner, "A unifying role for prions in neurodegenerative diseases," Science 336: 1511-13 (2012).
-
(2012)
Science
, vol.336
, pp. 1511-1513
-
-
Prusiner, S.B.1
-
6
-
-
72849160194
-
A neurological syndrome associated with orthostatic hypotension: A clinical-pathologic study
-
G. M. Shy and G. A. Drager, "A neurological syndrome associated with orthostatic hypotension: A clinical-pathologic study," Arch. Neurol. 2: 511-27 (1960).
-
(1960)
Arch. Neurol.
, vol.2
, pp. 511-527
-
-
Shy, G.M.1
Drager, G.A.2
-
7
-
-
0031568530
-
A further fond farewell to Shy and Drager
-
W. K. Engel, "A further fond farewell to Shy and Drager," Ann. Intern. Med. 126: 334 (1997);
-
(1997)
Ann. Intern. Med.
, vol.126
, pp. 334
-
-
Engel, W.K.1
-
8
-
-
0030318655
-
Farewell to the 'Shy-Drager syndrome'
-
I. J. Schatz, "Farewell to the 'Shy-Drager syndrome,' " Ann. Intern. Med. 125: 74-75 (1996).
-
(1996)
Ann. Intern. Med.
, vol.125
, pp. 74-75
-
-
Schatz, I.J.1
-
9
-
-
1542332334
-
The method of multiple working hypotheses
-
T. C. Chamberlin, "The method of multiple working hypotheses," Science [Old Series] 15: 92-97 (1890).
-
(1890)
Science [Old Series]
, vol.15
, pp. 92-97
-
-
Chamberlin, T.C.1
-
10
-
-
0014378550
-
Hypothermic protection against ce re bral edema of ischemia
-
S. Prusiner and S. K. Wolfson, Jr., "Hypothermic protection against ce re bral edema of ischemia," Arch. Neurol. 19: 623-27 (1968).
-
(1968)
Arch. Neurol.
, vol.19
, pp. 623-627
-
-
Prusiner, S.1
Wolfson, S.K.2
-
11
-
-
84893447249
-
Tolerance of the vestibular apparatus of the hypothermic hamster to 840G acceleration
-
B. Black-Schaff er, S. Prusiner, and H. Esparza, "Tolerance of the vestibular apparatus of the hypothermic hamster to 840G acceleration," Aerospace Med. 36: 123-26 (1965).
-
(1965)
Aerospace Med.
, vol.36
, pp. 123-126
-
-
Black-Schaffer, B.1
Prusiner, S.2
Esparza, H.3
-
12
-
-
0014248141
-
Pyridine nucleotide changes during thermogenesis in brown fat tissue in vivo
-
S. Prusiner, J. R. Williamson, B. Chance, and B. M. Paddle, "Pyridine nucleotide changes during thermogenesis in brown fat tissue in vivo," Arch. Biochem. Biophys. 123: 368-77 (1968).
-
(1968)
Arch. Biochem. Biophys.
, vol.123
, pp. 368-377
-
-
Prusiner, S.1
Williamson, J.R.2
Chance, B.3
Paddle, B.M.4
-
13
-
-
0014430962
-
Creutzfeldt-Jakob disease (spongiform encephalopathy): Transmission to the chimpanzee
-
C. J. Gibbs, Jr., D. C. Gajdusek, D. M. Asher, M. P. Alpers, E. Beck, P. M. Daniel, and W. B. Matthews, "Creutzfeldt-Jakob disease (spongiform encephalopathy): Transmission to the chimpanzee," Science 161: 388-89 (1968).
-
(1968)
Science
, vol.161
, pp. 388-389
-
-
Gibbs, C.J.1
Gajdusek, D.C.2
Asher, D.M.3
Alpers, M.P.4
Beck, E.5
Daniel, P.M.6
Matthews, W.B.7
-
14
-
-
0014021742
-
Experimental transmission of a kuru-like syndrome to chimpanzees
-
D. C. Gajdusek, C. J. Gibbs, Jr., and M. Alpers, "Experimental transmission of a kuru-like syndrome to chimpanzees," Nature 209: 794-96 (1966).
-
(1966)
Nature
, vol.209
, pp. 794-796
-
-
Gajdusek, D.C.1
Gibbs, C.J.2
Alpers, M.3
-
15
-
-
0014211846
-
Does the agent of scrapie replicate without nucleic acid
-
T. Alper, W. A. Cramp, D. A. Haig, and M. C. Clarke, "Does the agent of scrapie replicate without nucleic acid" Nature 214: 764-66 (1967).
-
(1967)
Nature
, vol.214
, pp. 764-766
-
-
Alper, T.1
Cramp, W.A.2
Haig, D.A.3
Clarke, M.C.4
-
16
-
-
84903229102
-
Interviews with Robert A. Fishman, M.D. Building Neurology, Teaching, Research, and Patient Care
-
Regents of the University of California, San Francisco,University of California, San Francisco
-
University of California, San Francisco, "Interviews with Robert A. Fishman, M.D.: Building Neurology, Teaching, Research, and Patient Care," in the UCSF Oral History Program, Department of the History of Health Sciences (Regents of the University of California, San Francisco, 1998).
-
(1998)
In the UCSF Oral History Program, Department of the History of Health Sciences
-
-
-
17
-
-
49749206702
-
Encephalopathy in mice produced by inoculation with scrapie brain material
-
R. L. Chandler, "Encephalopathy in mice produced by inoculation with scrapie brain material," Lancet 1, no. 719: 1378-79 (1961).
-
(1961)
Lancet 1
, Issue.719
, pp. 1378-1379
-
-
Chandler, R.L.1
-
19
-
-
0014963710
-
Inactivation of the scrapie agent by near monochromatic ultraviolet light
-
R. Latarjet, B. Muel, D. A. Haig, M. C. Clarke, and T. Alper, "Inactivation of the scrapie agent by near monochromatic ultraviolet light," Nature 227: 1341-43 (1970).
-
(1970)
Nature
, vol.227
, pp. 1341-1343
-
-
Latarjet, R.1
Muel, B.2
Haig, D.A.3
Clarke, M.C.4
Alper, T.5
-
20
-
-
0014190760
-
Nature of the scrapie agent: Self-replication and scrapie
-
J. S. Griffi th, "Nature of the scrapie agent: Self-replication and scrapie," Nature 215: 1043-44 (1967).
-
(1967)
Nature
, vol.215
, pp. 1043-1044
-
-
Griffith, J.S.1
-
21
-
-
0017643758
-
Unconventional viruses and the origin and disappearance of kuru
-
D. C. Gajdusek, "Unconventional viruses and the origin and disappearance of kuru," Science: 197: 943-60 (1977).
-
(1977)
Science:
, vol.197
, pp. 943-960
-
-
Gajdusek, D.C.1
-
22
-
-
0024296125
-
Fift y years with scrapie: A personal reminiscence
-
I. H. Pattison, "Fift y years with scrapie: A personal reminiscence," Vet. Rec. 123: 661-66 (1988).
-
(1988)
Vet. Rec.
, vol.123
, pp. 661-666
-
-
Pattison, I.H.1
-
23
-
-
49749220574
-
Scrapie and kuru
-
W. J. Hadlow, "Scrapie and kuru," Lancet 2, no. 289-90 (1959).
-
(1959)
Lancet
, vol.2
, pp. 289-290
-
-
Hadlow, W.J.1
-
24
-
-
0017820150
-
An approach to the isolation of biological particles using sedimentation analysis
-
S. B. Prusiner, "An approach to the isolation of biological particles using sedimentation analysis," J. Biol. Chem. 253: 916-21 (1978).
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 916-921
-
-
Prusiner, S.B.1
-
25
-
-
0348169164
-
Sedimentation properties of the scrapie agent
-
S. B. Prusiner, W. J. Hadlow, C. M. Eklund, and R. E. Race, "Sedimentation properties of the scrapie agent," Proc. Natl. Acad. Sci. USA 74: 4656-60 (1977).
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 4656-4660
-
-
Prusiner, S.B.1
Hadlow, W.J.2
Eklund, C.M.3
Race, R.E.4
-
26
-
-
0018711812
-
Evaluation of a class III biological safety cabinet for enclosure of an ultracentrifuge
-
M. A. Chatigny, K. Ishimaru, S. Dunn, J. A. Ea gleson, and S. B. Prusiner, "Evaluation of a class III biological safety cabinet for enclosure of an ultracentrifuge," Appl. Environ. Microbiol. 38: 934-39 (1979).
-
(1979)
Appl. Environ. Microbiol.
, vol.38
, pp. 934-939
-
-
Chatigny, M.A.1
Ishimaru, K.2
Dunn, S.3
Eagleson, J.A.4
Prusiner, S.B.5
-
28
-
-
84903245545
-
The enigma of the scrapie agent: Biochemical approaches and the involvement of membranes and nucleic acids
-
Academic Press, New York
-
G. D. Hunter, "The enigma of the scrapie agent: Biochemical approaches and the involvement of membranes and nucleic acids," in Slow Transmissible Diseases of the Ner vous System, vol. 2, ed. S. B. Prusiner and W. J. Hadlow (Academic Press, New York, 1979), 365-85.
-
(1979)
In Slow Transmissible Diseases of the Ner vous System, vol. 2, ed. S. B. Prusiner and W. J. Hadlow
, pp. 365-385
-
-
Hunter, G.D.1
-
29
-
-
0014998495
-
An experimental examination of the scrapie agent in cell membrane mixtures.I. Stability and physicochemical properties of the scrapie agent
-
G. D. Hunter, R. H. Kimberlin, G. C. Millson, and R. A. Gibbons, "An experimental examination of the scrapie agent in cell membrane mixtures. I. Stability and physicochemical properties of the scrapie agent," J. Comp. Pathol. 81: 23-32 (1971);
-
(1971)
J. Comp. Pathol.
, vol.81
, pp. 23-32
-
-
Hunter, G.D.1
Kimberlin, R.H.2
Millson, G.C.3
Gibbons, R.A.4
-
30
-
-
0015051426
-
An experimental examination of the scrapie agent in cell membrane mixtures. II. The association of scrapie infectivity with membrane fractions
-
G. C. Millson, G. D. Hunter, and R. H. Kimberlin, "An experimental examination of the scrapie agent in cell membrane mixtures. II. The association of scrapie infectivity with membrane fractions," J. Comp. Pathol. 81: 255-65 (1971);
-
(1971)
J. Comp. Pathol.
, vol.81
, pp. 255-265
-
-
Millson, G.C.1
Hunter, G.D.2
Kimberlin, R.H.3
-
31
-
-
0015092902
-
An experimental examination of the scrapie agent in cell membrane mixtures. III. Studies of the operational size
-
R. H. Kimberlin, G. C. Millson, and G. D. Hunter, "An experimental examination of the scrapie agent in cell membrane mixtures. III. Studies of the operational size," J. Comp. Pathol. 81: 383-91 (1971).
-
(1971)
J. Comp. Pathol.
, vol.81
, pp. 383-391
-
-
Kimberlin, R.H.1
Millson, G.C.2
Hunter, G.D.3
-
32
-
-
0037476130
-
Scrapie-virus or viroid: The case for a virus
-
Verlag Chemie, Weinheim, ed. A. Boese
-
R. G. Rohwer and D. C. Gajdusek, "Scrapie-virus or viroid: The case for a virus," in Search for the Cause of Multiple Sclerosis and Other Chronic Diseases of the Central Ner vous System, ed. A. Boese (Verlag Chemie, Weinheim, 1980), 333-55.
-
(1980)
In Search for the Cause of Multiple Sclerosis and Other Chronic Diseases of the Central Ner vous System
, pp. 333-355
-
-
Rohwer, R.G.1
Gajdusek, D.C.2
-
33
-
-
0017375264
-
Virus-like particles from both control and scrapie-aff ected mouse brain
-
H. J. Cho, A. S. Grieg, C. R. Corp, R. H. Kimberlin, R. L. Chandler, and G. C. Millson, "Virus-like particles from both control and scrapie-aff ected mouse brain," Nature 267: 459-60 (1977).
-
(1977)
Nature
, vol.267
, pp. 459-460
-
-
Cho, H.J.1
Grieg, A.S.2
Corp, C.R.3
Kimberlin, R.H.4
Chandler, R.L.5
Millson, G.C.6
-
34
-
-
0014234258
-
Scrapie in mice: Ultrastructural observations in the ce re bral cortex
-
J. F. David-Ferreira, K. L. David-Ferreira, C. J. Gibbs, Jr., and J. A. Morris, "Scrapie in mice: Ultrastructural observations in the ce re bral cortex," Proc. Soc. Exp. Biol. Med. 127: 313-20 (1968).
-
(1968)
Proc. Soc. Exp. Biol. Med.
, vol.127
, pp. 313-320
-
-
David-Ferreira, J.F.1
David-Ferreira, K.L.2
Gibbs, C.J.3
Morris, J.A.4
-
35
-
-
0017822942
-
Experimental scrapie in mice: Ultrastructural observations
-
J. R. Baringer and S. B. Prusiner, "Experimental scrapie in mice: Ultrastructural observations," Ann. Neurol. 4: 205-11 (1978).
-
(1978)
Ann. Neurol.
, vol.4
, pp. 205-211
-
-
Baringer, J.R.1
Prusiner, S.B.2
-
36
-
-
0000087268
-
An assessment of the ge ne tics of scrapie in sheep and mice
-
Academic Press, New York
-
A. G. Dickinson and G. W. Outram, "An assessment of the ge ne tics of scrapie in sheep and mice," in Slow Transmissible Diseases of the Ner vous System, ed. S. B. Prusiner and W. J. Hadlow (Academic Press, New York, 1979), 1: 367-86.
-
(1979)
In Slow Transmissible Diseases of the Ner vous System, ed. S. B. Prusiner and W. J. Hadlow
, vol.1
, pp. 367-386
-
-
Dickinson, A.G.1
Outram, G.W.2
-
37
-
-
0020481648
-
Scrapie agent: Prions or virinos
-
R. H. Kimberlin, "Scrapie agent: Prions or virinos" Nature 297: 107-8 (1982).
-
(1982)
Nature
, vol.297
, pp. 107-108
-
-
Kimberlin, R.H.1
-
38
-
-
0018091723
-
Evidence for an essential DNA component in the scrapie agent
-
R. F. Marsh, T. G. Malone, J. S. Semancik, W. D. Lancaster, and R. P. Hanson, "Evidence for an essential DNA component in the scrapie agent," Nature 275: 146-47 (1978).
-
(1978)
Nature
, vol.275
, pp. 146-147
-
-
Marsh, R.F.1
Malone, T.G.2
Semancik, J.S.3
Lancaster, W.D.4
Hanson, R.P.5
-
39
-
-
2442490085
-
Scrapie agent contains a hydrophobic protein
-
S. B. Prusiner, M. P. McKinley, D. F. Groth, K. A. Bowman, N. I. Mock, S. P. Cochran, and F. R. Masiarz, "Scrapie agent contains a hydrophobic protein," Proc. Natl. Acad. Sci. USA 78: 6675-79 (1981).
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 6675-6679
-
-
Prusiner, S.B.1
McKinley, M.P.2
Groth, D.F.3
Bowman, K.A.4
Mock, N.I.5
Cochran, S.P.6
Masiarz, F.R.7
-
40
-
-
78651031919
-
Kuru: Clinical study of a new syndrome resembling paralysis agitans in natives of the Eastern Highlands of Australian New Guinea
-
V. Zigas and D. C. Gajdusek, "Kuru: Clinical study of a new syndrome resembling paralysis agitans in natives of the Eastern Highlands of Australian New Guinea," Med. J. Australia 44: 745-54 (1957).
-
(1957)
Med. J. Australia
, vol.44
, pp. 745-754
-
-
Zigas, V.1
Gajdusek, D.C.2
-
42
-
-
84903229104
-
-
(Williams and Wilkins, Baltimore)
-
O. T. Bailey and D. E. Smith (Williams and Wilkins, Baltimore, 1968), 234-51.
-
(1968)
, pp. 234-251
-
-
Bailey, O.T.1
Smith, D.E.2
-
43
-
-
0014080385
-
Cannibalism in the kuru region of New Guinea
-
R. Glasse, "Cannibalism in the kuru region of New Guinea," Trans. N.Y. Acad. Sci. [Series 2] 29: 748-54 (1967).
-
(1967)
Trans. N.Y. Acad. Sci. [Series 2]
, vol.29
, pp. 748-754
-
-
Glasse, R.1
-
44
-
-
68849099453
-
Cannibalism, kuru, and anthropology
-
S. Lindenbaum, "Cannibalism, kuru, and anthropology," Folia Neuropathol. 47: 138-44 (2009).
-
(2009)
Folia Neuropathol.
, vol.47
, pp. 138-144
-
-
Lindenbaum, S.1
-
45
-
-
0018936053
-
Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates
-
C. J. Gibbs, Jr., H. L. Amyx, A. Bacote, C. L. Masters, and D. C. Gajdusek, "Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates," J. Infect. Dis. 142: 205-8 (1980).
-
(1980)
J. Infect. Dis.
, vol.142
, pp. 205-208
-
-
Gibbs, C.J.1
Amyx, H.L.2
Bacote, A.3
Masters, C.L.4
Gajdusek, D.C.5
-
46
-
-
51849177198
-
Über eigenartige Erkrankungen des Zentralnervensystems mit bemerkenswertem anatomischem Befunde (Spastische Pseudosklerose-Encephalomyelopathie mit disseminierten Degenerationsherden)
-
A. Jakob, "Über eigenartige Erkrankungen des Zentralnervensystems mit bemerkenswertem anatomischem Befunde (Spastische Pseudosklerose-Encephalomyelopathie mit disseminierten Degenerationsherden)," Z. Gesamte Neurol. Psychiatr. 64: 147-228 (1921).
-
(1921)
Z. Gesamte Neurol. Psychiatr.
, vol.64
, pp. 147-228
-
-
Jakob, A.1
-
47
-
-
33746127253
-
Über eine eigenartige herdförmige Erkrankung des Zentralnervensystems
-
H. G. Creutzfeldt, "Über eine eigenartige herdförmige Erkrankung des Zentralnervensystems," Z. Gesamte Neurol. Psychiatr. 57: 1-18 (1920).
-
(1920)
Z. Gesamte Neurol. Psychiatr.
, vol.57
, pp. 1-18
-
-
Creutzfeldt, H.G.1
-
48
-
-
57349181644
-
Spongiform encephalopathies-slow, latent, and temperate virus infections-in retrospect
-
ed. S. B. Prusiner, J. Collinge, J. Powell, and B. Anderton (Ellis Horwood, London)
-
C. J. Gibbs, Jr., "Spongiform encephalopathies-slow, latent, and temperate virus infections-in retrospect," in Prion Diseases of Humans and Animals, ed. S. B. Prusiner, J. Collinge, J. Powell, and B. Anderton (Ellis Horwood, London, 1992), 53-62.
-
(1992)
In Prion Diseases of Humans and Animals
, pp. 53-62
-
-
Gibbs, C.J.1
-
49
-
-
0014258955
-
Kuru-a subacute cerebellar degeneration: The natural history and clinical features
-
R. W. Hornabrook, "Kuru-a subacute cerebellar degeneration: The natural history and clinical features," Brain 91: 53-74 (1968).
-
(1968)
Brain
, vol.91
, pp. 53-74
-
-
Hornabrook, R.W.1
-
51
-
-
0016468829
-
Comparison of scrapie and transmissible mink encephalopathy in hamsters. I. Biochemical studies of brain during development of disease
-
R. H. Kimberlin and R. F. Marsh, "Comparison of scrapie and transmissible mink encephalopathy in hamsters. I. Biochemical studies of brain during development of disease," J. Infect. Dis. 131: 97-103 (1975);
-
(1975)
J. Infect. Dis.
, vol.131
, pp. 97-103
-
-
Kimberlin, R.H.1
Marsh, R.F.2
-
52
-
-
0016469066
-
Comparison of scrapie and transmissible mink encephalopathy in hamsters. II. Clinical signs, pathology, and pathogenesis
-
R. F. Marsh and R. H. Kimberlin, "Comparison of scrapie and transmissible mink encephalopathy in hamsters. II. Clinical signs, pathology, and pathogenesis," J. Infect. Dis. 131: 104-10 (1975).
-
(1975)
J. Infect. Dis.
, vol.131
, pp. 104-110
-
-
Marsh, R.F.1
Kimberlin, R.H.2
-
53
-
-
84903229102
-
Interviews with Robert A. Fishman, M.D.: Building Neurology, Teaching, Research, and Patient Care
-
University of California, San Francisco,(Regents of the University of California, San Francisco)
-
University of California, San Francisco, "Interviews with Robert A. Fishman, M.D.: Building Neurology, Teaching, Research, and Patient Care," in the UCSF Oral History Program, Department of the History of Health Sciences (Regents of the University of California, San Francisco, 1998).
-
(1998)
In the UCSF Oral History Program, Department of the History of Health Sciences
-
-
-
54
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
S. B. Prusiner, "Novel proteinaceous infectious particles cause scrapie," Science 216: 136-44 (1982).
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
55
-
-
0020481648
-
Scrapie agent: Prions or virinos
-
R. H. Kimberlin, "Scrapie agent: Prions or virinos" Nature 297: 107-8 (1982).
-
(1982)
Nature
, vol.297
, pp. 107-108
-
-
Kimberlin, R.H.1
-
56
-
-
0018215610
-
Unusual re sis tance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie
-
C. J. Gibbs, Jr., D. C. Gajdusek, and R. Latarjet, "Unusual re sis tance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie," Proc. Nat. Acad. Sci. USA 75: 6268-70 (1978).
-
(1978)
Proc. Nat. Acad. Sci. USA
, vol.75
, pp. 6268-6270
-
-
Gibbs, C.J.1
Gajdusek, D.C.2
Latarjet, R.3
-
57
-
-
49049130230
-
The novel nature of scrapie
-
R. T. Johnson, "The novel nature of scrapie." Trends Neurosci. 5: 413-15 (1982).
-
(1982)
Trends Neurosci.
, vol.5
, pp. 413-415
-
-
Johnson, R.T.1
-
59
-
-
84983711696
-
Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a deoxyribonucleic acid fraction isolated from pneumococcus type III
-
O. T. Avery, C. M. MacLeod, and M. McCarty, "Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a deoxyribonucleic acid fraction isolated from pneumococcus type III," J. Exp. Med. 79: 137-57 (1944).
-
(1944)
J. Exp. Med.
, vol.79
, pp. 137-157
-
-
Avery, O.T.1
MacLeod, C.M.2
McCarty, M.3
-
60
-
-
0020490156
-
Identifi cation of a protein that purifi es with the scrapie prion
-
D. C. Bolton, M. P. McKinley, and S. B. Prusiner, "Identifi cation of a protein that purifi es with the scrapie prion," Science 218: 1309-11 (1982).
-
(1982)
Science
, vol.218
, pp. 1309-1311
-
-
Bolton, D.C.1
McKinley, M.P.2
Prusiner, S.B.3
-
61
-
-
0020285570
-
Further purifi cation and characterization of scrapie prions
-
S. B. Prusiner, D. C. Bolton, D. F. Groth, K. A. Bowman, S. P. Cochran, and M. P. McKinley, "Further purifi cation and characterization of scrapie prions," Biochemistry 21: 6942-50 (1982).
-
(1982)
Biochemistry
, vol.21
, pp. 6942-6950
-
-
Prusiner, S.B.1
Bolton, D.C.2
Groth, D.F.3
Bowman, K.A.4
Cochran, S.P.5
McKinley, M.P.6
-
62
-
-
0021023167
-
A proteaseresistant protein is a structural component of the scrapie prion
-
M. P. McKinley, D. C. Bolton, and S. B. Prusiner, "A proteaseresistant protein is a structural component of the scrapie prion," Cell 35: 57-62 (1983).
-
(1983)
Cell
, vol.35
, pp. 57-62
-
-
McKinley, M.P.1
Bolton, D.C.2
Prusiner, S.B.3
-
63
-
-
0014409646
-
Failure to demonstrate a relationship between scrapie and production of interferon in mice
-
M. Katz and H. Koprowski, "Failure to demonstrate a relationship between scrapie and production of interferon in mice," Nature 219: 639-40 (1968).
-
(1968)
Nature
, vol.219
, pp. 639-640
-
-
Katz, M.1
Koprowski, H.2
-
64
-
-
84903229059
-
The doctor's world: The mystery of Balanchine's death is solved
-
May 8
-
L. K. Altman, "The doctor's world: The mystery of Balanchine's death is solved," New York Times, May 8, 1984.
-
(1984)
New York Times
-
-
Altman, L.K.1
-
65
-
-
0020285570
-
Further purifi cation and characterization of scrapie prions
-
S. B. Prusiner, D. C. Bolton, D. F. Groth, K. A. Bowman, S. P. Cochran, and M. P. McKinley, "Further purifi cation and characterization of scrapie prions," Biochemistry 21: 6942-50 (1982).
-
(1982)
Biochemistry
, vol.21
, pp. 6942-6950
-
-
Prusiner, S.B.1
Bolton, D.C.2
Groth, D.F.3
Bowman, K.A.4
Cochran, S.P.5
McKinley, M.P.6
-
66
-
-
0000844417
-
Electron microscopy of amyloid
-
ed. J. R. Harris (Academic Press, New York)
-
A. S. Cohen, T. Shirahama, and M. Skinner, "Electron microscopy of amyloid," in the Electron Microscopy of Proteins, vol. 3, ed. J. R. Harris (Academic Press, New York, 1982), 165-206.
-
(1982)
In the Electron Microscopy of Proteins
, vol.3
, pp. 165-206
-
-
Cohen, A.S.1
Shirahama, T.2
Skinner, M.3
-
67
-
-
0000930795
-
Etude histochimique des plaques seniles
-
P. Divry, "Etude histochimique des plaques seniles," J. Belge Neurol. Psychiatrie 27: 643-54 (1927).
-
(1927)
J. Belge Neurol. Psychiatrie
, vol.27
, pp. 643-654
-
-
Divry, P.1
-
69
-
-
0021019026
-
Scrapie prions aggregate to form amyloid-like birefringent rods
-
S. B. Prusiner, M. P. McKinley, K. A. Bowman, D. C. Bolton, P. E. Bendheim, D. F. Groth, and G. G. Glenner, "Scrapie prions aggregate to form amyloid-like birefringent rods," Cell 35: 349-58 (1983).
-
(1983)
Cell
, vol.35
, pp. 349-358
-
-
Prusiner, S.B.1
McKinley, M.P.2
Bowman, K.A.3
Bolton, D.C.4
Bendheim, P.E.5
Groth, D.F.6
Glenner, G.G.7
-
70
-
-
84903229060
-
Substance tied to Alzheimer's in Coast study
-
December 7
-
L. K. Altman, "Substance tied to Alzheimer's in Coast study," New York Times, December 7, 1983.
-
(1983)
New York Times
-
-
Altman, L.K.1
-
71
-
-
0003054711
-
The name of the game is fame. But is it science
-
G. Taubes, "the name of the game is fame. But is it science" Discover 7: 28-52 (1986).
-
(1986)
Discover
, vol.7
, pp. 28-52
-
-
Taubes, G.1
-
72
-
-
0021256895
-
Alzheimer's disease: Initial report of the purifi cation and characterization of a novel cerebrovascular amyloid protein
-
G. G. Glenner and C. W. Wong, "Alzheimer's disease: Initial report of the purifi cation and characterization of a novel cerebrovascular amyloid protein," Biochem. Biophys. Res. Commun. 120: 885-90 (1984).
-
(1984)
Biochem. Biophys. Res. Commun
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
73
-
-
0021344124
-
Some speculations about prions, amyloid, and Alzheimer's disease
-
S. B. Prusiner, "Some speculations about prions, amyloid, and Alzheimer's disease," N. Engl. J. Med. 310: 661-63 (1984).
-
(1984)
N. Engl. J. Med
, vol.310
, pp. 661-663
-
-
Prusiner, S.B.1
-
74
-
-
0021193353
-
Antibodies to a scrapie prion protein
-
P. E. Bendheim, R. A. Barry, S. J. De Armond, D. P. Stites, and S. B. Prusiner, "Antibodies to a scrapie prion protein," Nature 310: 418-21 (1984).
-
(1984)
Nature
, vol.310
, pp. 418-421
-
-
Bendheim, P.E.1
Barry, R.A.2
De Armond, S.J.3
Stites, D.P.4
Prusiner, S.B.5
-
75
-
-
0021879270
-
Identifi cation of prion amyloid fi laments in scrapie-infected brain
-
S. J. DeArmond, M. P. McKinley, R. A. Barry, M. B. Braunfeld, J. R. McColloch, and S. B. Prusiner, "Identifi cation of prion amyloid fi laments in scrapie-infected brain," Cell 41: 221-35 (1985).
-
(1985)
Cell
, vol.41
, pp. 221-235
-
-
DeArmond, S.J.1
McKinley, M.P.2
Barry, R.A.3
Braunfeld, M.B.4
McColloch, J.R.5
Prusiner, S.B.6
-
76
-
-
0013539185
-
Molecular pathology of prion diseases
-
ed. S. B. Prusiner and M. P. McKinley (Academic Press, Orlando, Fla.)
-
S. J. DeArmond, H. A. Kretzschmar, M. P. McKinley, and S. B. Prusiner, "Molecular pathology of prion diseases," in Prions: Novel Infectious Pathogens Causing Scrapie and Creutzfeldt-Jakob Disease, ed. S. B. Prusiner and M. P. McKinley (Academic Press, Orlando, Fla., 1987) 387-414.
-
(1987)
In Prions: Novel Infectious Pathogens Causing Scrapie and Creutzfeldt-Jakob Disease
, pp. 387-414
-
-
DeArmond, S.J.1
Kretzschmar, H.A.2
McKinley, M.P.3
Prusiner, S.B.4
-
77
-
-
0020511509
-
Ultrastructural morphology of amyloid fi brils from neuritic and amyloid plaques
-
P. A. Merz, H. M. Wisniewski, R. A. Somerville, S. A. Bobin, C. L. Masters, and K. Iqbal, "Ultrastructural morphology of amyloid fi brils from neuritic and amyloid plaques," Acta Neuropathol. (Berl.) 60: 113-24 (1983).
-
(1983)
Acta Neuropathol. (Berl.)
, vol.60
, pp. 113-124
-
-
Merz, P.A.1
Wisniewski, H.M.2
Somerville, R.A.3
Bobin, S.A.4
Masters, C.L.5
Iqbal, K.6
-
78
-
-
0021036329
-
Scrapie infectivity, fi brils and low molecular weight protein
-
H. Diringer, H. Gelderblom, H. Hilmert, M. Ozel, C. Edelbluth, and R. H. Kimberlin, "Scrapie infectivity, fi brils and low molecular weight protein," Nature 306: 476-78 (1983).
-
(1983)
Nature
, vol.306
, pp. 476-478
-
-
Diringer, H.1
Gelderblom, H.2
Hilmert, H.3
Ozel, M.4
Edelbluth, C.5
Kimberlin, R.H.6
-
79
-
-
0021176718
-
Infection-specifi c particle from the unconventional slow virus diseases
-
P. A. Merz, R. G. Rohwer, R. Kascsak, H. M. Wisniewski, R. A. Somerville, C. J. Gibbs, Jr., and D. C. Gajdusek, "Infection-specifi c particle from the unconventional slow virus diseases," Science 225: 437-40 (1984).
-
(1984)
Science
, vol.225
, pp. 437-440
-
-
Merz, P.A.1
Rohwer, R.G.2
Kascsak, R.3
Wisniewski, H.M.4
Somerville, R.A.5
Gibbs, C.J.6
Gajdusek, D.C.7
-
80
-
-
0000857618
-
Subacute spongiform encephalopathies: Transmissible ce re bral amyloidoses caused by unconventional viruses
-
2nd ed. B. N. Fields, D. M. Knipe, R. M. Chanock, M. S. Hirsch, J. L. Melnick, T. P. Monath, and B. Roizman [Raven, New York]
-
D. C. Gajdusek, "Subacute spongiform encephalopathies: Transmissible ce re bral amyloidoses caused by unconventional viruses," in Virology, 2nd ed. B. N. Fields, D. M. Knipe, R. M. Chanock, M. S. Hirsch, J. L. Melnick, T. P. Monath, and B. Roizman [Raven, New York, 1990], 2289-324.
-
(1990)
In Virology
, pp. 2289-2324
-
-
Gajdusek, D.C.1
-
81
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
S. B. Prusiner, "Novel proteinaceous infectious particles cause scrapie," Science 216: 136-44 (1982).
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
82
-
-
68149132445
-
Structural insights into nonribosomal peptide enzymatic assembly lines
-
A. Koglin and C. T. Walsh, "Structural insights into nonribosomal peptide enzymatic assembly lines," Nat. Prod. Rep. 26: 987-1000 (2009).
-
(2009)
Nat. Prod. Rep
, vol.26
, pp. 987-1000
-
-
Koglin, A.1
Walsh, C.T.2
-
83
-
-
0021752457
-
Purifi cation and structural studies of a major scrapie prion protein
-
S. B. Prusiner, D. F. Groth, D. C. Bolton, S. B. Kent, and L. E. Hood, "Purifi cation and structural studies of a major scrapie prion protein," Cell 38: 127-34 (1984).
-
(1984)
Cell
, vol.38
, pp. 127-134
-
-
Prusiner, S.B.1
Groth, D.F.2
Bolton, D.C.3
Kent, S.B.4
Hood, L.E.5
-
84
-
-
0022005315
-
A cellular gene encodes scrapie PrP 27-30 protein
-
B. Oesch, D. Westaway, M. Wälchli, M. P. McKinley, S. B. H. Kent, R. Aebersold, R. A. Barry, P. Tempst, D. B. Teplow, L. E. Hood, S. B. Prusiner, and C. Weissmann, "A cellular gene encodes scrapie PrP 27-30 protein," Cell 40: 735-46 (1985).
-
(1985)
Cell
, vol.40
, pp. 735-746
-
-
Oesch, B.1
Westaway, D.2
Wälchli, M.3
McKinley, M.P.4
Kent, S.B.H.5
Aebersold, R.6
Barry, R.A.7
Tempst, P.8
Teplow, D.B.9
Hood, L.E.10
Prusiner, S.B.11
Weissmann, C.12
-
85
-
-
0021884354
-
Identifi cation of scrapie prion protein-specifi c mRNA in scrapie-infected and uninfected brain
-
B. Chesebro, R. Race, K. Wehrly, J. Nishio, M. Bloom, D. Lechner, S. Bergstrom, K. Robbins, L. Mayer, J. M. Keith, C. Garon, and A. Haase, "Identifi cation of scrapie prion protein-specifi c mRNA in scrapie-infected and uninfected brain," Nature 315: 331-33 (1985).
-
(1985)
Nature
, vol.315
, pp. 331-333
-
-
Chesebro, B.1
Race, R.2
Wehrly, K.3
Nishio, J.4
Bloom, M.5
Lechner, D.6
Bergstrom, S.7
Robbins, K.8
Mayer, L.9
Keith, J.M.10
Garon, C.11
Haase, A.12
-
86
-
-
0020521924
-
Ge ne tic control of scrapie and Creutzfeldt-Jakob disease in mice
-
D. T. Kingsbury, K. C. Kasper, D. P. Stites, J. D. Watson, R. N. Hogan, and S. B. Prusiner, "Ge ne tic control of scrapie and Creutzfeldt-Jakob disease in mice," J. Immunol. 131: 491-96 (1983).
-
(1983)
J. Immunol
, vol.131
, pp. 491-496
-
-
Kingsbury, D.T.1
Kasper, K.C.2
Stites, D.P.3
Watson, J.D.4
Hogan, R.N.5
Prusiner, S.B.6
-
87
-
-
0014305661
-
Identifi cation of a gene which controls the incubation period of some strains of scrapie agent in mice
-
A. G. Dickinson, V. M. H. Meikle, and H. Fraser, "Identifi cation of a gene which controls the incubation period of some strains of scrapie agent in mice," J. Comp. Pathol. 78: 293-99 (1968).
-
(1968)
J. Comp. Pathol
, vol.78
, pp. 293-299
-
-
Dickinson, A.G.1
Meikle, V.M.H.2
Fraser, H.3
-
88
-
-
84903251760
-
Prions and prejudice: From Sinc to systems with Stan
-
ed. G. Legname and D. Riesner (Düsseldorf University Press, Düsseldorf)
-
G. A. Carlson, "Prions and prejudice: From Sinc to systems with Stan," in Prion Research of Stan Prusiner and His Colleagues, ed. G. Legname and D. Riesner (Düsseldorf University Press, Düsseldorf, 2013), 47-61.
-
(2013)
In Prion Research of Stan Prusiner and His Colleagues
, pp. 47-61
-
-
Carlson, G.A.1
-
89
-
-
0022530549
-
Linkage of prion protein and scrapie incubation time genes
-
G. A. Carlson, D. T. Kingsbury, P. A. Goodman, S. Coleman, S. T. Marshall, S. DeArmond, D. Westaway, and S. B. Prusiner, "Linkage of prion protein and scrapie incubation time genes," Cell 46: 503-11 (1986).
-
(1986)
Cell
, vol.46
, pp. 503-511
-
-
Carlson, G.A.1
Kingsbury, D.T.2
Goodman, P.A.3
Coleman, S.4
Marshall, S.T.5
de Armond, S.6
Westaway, D.7
Prusiner, S.B.8
-
90
-
-
0023467393
-
Distinct prion proteins in short and long scrapie incubation period mice
-
D. Westaway, P. A. Goodman, C. A. Mirenda, M. P. McKinley, G. A. Carlson, and S. B. Prusiner, "Distinct prion proteins in short and long scrapie incubation period mice," Cell 51: 651-62 (1987).
-
(1987)
Cell
, vol.51
, pp. 651-662
-
-
Westaway, D.1
Goodman, P.A.2
Mirenda, C.A.3
McKinley, M.P.4
Carlson, G.A.5
Prusiner, S.B.6
-
91
-
-
0023430390
-
Linkage of the scrapie-associated fi bril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis
-
N. Hunter, J. Hope, I. McConnell, and A. G. Dickinson, "Linkage of the scrapie-associated fi bril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis," J. Gen. Virol. 68: 2711-16 (1987).
-
(1987)
J. Gen. Virol
, vol.68
, pp. 2711-2716
-
-
Hunter, N.1
Hope, J.2
McConnell, I.3
Dickinson, A.G.4
-
93
-
-
0003054711
-
The name of the game is fame. But is it science
-
G. Taubes, "the name of the game is fame. But is it science" Discover 7: 28-52 (1986).
-
(1986)
Discover
, vol.7
, pp. 28-52
-
-
Taubes, G.1
-
94
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
S. B. Prusiner, "Novel proteinaceous infectious particles cause scrapie," Science 216: 136-44 (1982).
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
95
-
-
84903245920
-
Prusiner and prions
-
C. Weissmann, "Prusiner and prions," Discover 8: 102 (1987).
-
(1987)
Discover
, vol.8
, pp. 102
-
-
Weissmann, C.1
-
96
-
-
0015549846
-
The clinical characteristics of transmissible Creutzfeldt-Jakob disease
-
R. Roos, D. C. Gajdusek, and C. J. Gibbs, Jr., "the clinical characteristics of transmissible Creutzfeldt-Jakob disease," Brain 96: 1-20 (1973).
-
(1973)
Brain
, vol.96
, pp. 1-20
-
-
Roos, R.1
Gajdusek, D.C.2
Gibbs, C.J.3
-
97
-
-
0019778656
-
Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Sträussler syndrome
-
C. L. Masters, D. C. Gajdusek, and C. J. Gibbs, Jr., "Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Sträussler syndrome," Brain 104: 559-88 (1981).
-
(1981)
Brain
, vol.104
, pp. 559-588
-
-
Masters, C.L.1
Gajdusek, D.C.2
Gibbs, C.J.3
-
98
-
-
51849178459
-
Über eine eigenartige hereditär-familiäre Erkrankung des Zentralnervensystems zugleich ein Beitrag zur frage des vorzeitigen lokalen Alterns
-
J. Gerstmann, E. Sträussler, and I. Scheinker, "Über eine eigenartige hereditär-familiäre Erkrankung des Zentralnervensystems zugleich ein Beitrag zur frage des vorzeitigen lokalen Alterns," Z. Neurol. 154: 736-62 (1936).
-
(1936)
Z. Neurol
, vol.154
, pp. 736-762
-
-
Gerstmann, J.1
Sträussler, E.2
Scheinker, I.3
-
99
-
-
0028990981
-
The original Gerstmann-Sträussler-Scheinker family of Austria: Divergent clinicopathological phenotypes but constant PrP genotype
-
J. A. Hainfellner, S. Brantner-Inthaler, L. Cervenáková, P. Brown, T. Kitamoto, J. Tateishi, H. Diringer, P. P. Liberski, H. Regele, M. Feucht, N. Mayr, P. Wessely, K. Summer, F. Seitelberger, and H. Budka, "the original Gerstmann-Sträussler-Scheinker family of Austria: divergent clinicopathological phenotypes but constant PrP genotype," Brain Pathol. 5: 201-11 (1995).
-
(1995)
Brain Pathol
, vol.5
, pp. 201-211
-
-
Hainfellner, J.A.1
Brantner-Inthaler, S.2
Cervenáková, L.3
Brown, P.4
Kitamoto, T.5
Tateishi, J.6
Diringer, H.7
Liberski, P.P.8
Regele, H.9
Feucht, M.10
Mayr, N.11
Wessely, P.12
Summer, K.13
Seitelberger, F.14
Budka, H.15
-
100
-
-
0024519771
-
Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome
-
K. Hsiao, H. F. Baker, T. J. Crow, M. Poulter, F. Owen, J. D. Terwilliger, D. Westaway, J. Ott, and S. B. Prusiner, "Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome," Nature 338: 342-45 (1989).
-
(1989)
Nature
, vol.338
, pp. 342-345
-
-
Hsiao, K.1
Baker, H.F.2
Crow, T.J.3
Poulter, M.4
Owen, F.5
Terwilliger, J.D.6
Westaway, D.7
Ott, J.8
Prusiner, S.B.9
-
101
-
-
0025237593
-
Subcellular distribution and physicochemical properties of scrapie-associated precursor protein and relationship with scrapie agent
-
J. Safar, M. Ceroni, P. Piccardo, P. P. Liberski, M. Miyazaki, D. C. Gajdusek, and C. J. Gibbs, Jr., "Subcellular distribution and physicochemical properties of scrapie-associated precursor protein and relationship with scrapie agent," Neurology 40: 503-8 (1990).
-
(1990)
Neurology
, vol.40
, pp. 503-508
-
-
Safar, J.1
Ceroni, M.2
Piccardo, P.3
Liberski, P.P.4
Miyazaki, M.5
Gajdusek, D.C.6
Gibbs, C.J.7
-
102
-
-
0025215432
-
Scrapie infectivity and prion protein are distributed in the same pH range in agarose isoelectric focusing
-
M. Ceroni, P. Piccardo, J. Safar, D. C. Gajdusek, and C. J. Gibbs, Jr., "Scrapie infectivity and prion protein are distributed in the same pH range in agarose isoelectric focusing," Neurology 40: 508-13 (1990).
-
(1990)
Neurology
, vol.40
, pp. 508-513
-
-
Ceroni, M.1
Piccardo, P.2
Safar, J.3
Gajdusek, D.C.4
Gibbs, C.J.5
-
103
-
-
0025237594
-
Crapie-associated precursor proteins: Antigenic relationship between species and immunocytochemical localization in normal, scrapie, and Creutzfeldt-Jakob disease brains
-
J. Safar, M. Ceroni, P. Piccardo, D. C. Gajdusek, and C. J. Gibbs, Jr., "Scrapie-associated precursor proteins: Antigenic relationship between species and immunocytochemical localization in normal, scrapie, and Creutzfeldt-Jakob disease brains," Neurology 40: 513-17 (1990).
-
(1990)
Neurology
, vol.40
, pp. 513-517
-
-
Safar, J.1
Ceroni, M.2
Piccardo, P.3
Gajdusek, D.C.4
Gibbs, C.J.5
-
104
-
-
0025219885
-
Immunohistochemical localization of prion protein in spongiform encephalopathies and normal brain tissue
-
P. Piccardo, J. Safar, M. Ceroni, D. C. Gajdusek, and C. J. Gibbs, Jr., "Immunohistochemical localization of prion protein in spongiform encephalopathies and normal brain tissue," Neurology 40: 518-22 (1990).
-
(1990)
Neurology
, vol.40
, pp. 518-522
-
-
Piccardo, P.1
Safar, J.2
Ceroni, M.3
Gajdusek, D.C.4
Gibbs, C.J.5
-
105
-
-
0024820814
-
Transgenic mice expressing hamster prion protein produce speciesspecifi c scrapie infectivity and amyloid plaques
-
M. Scott, D. Foster, C. Mirenda, D. Serban, F. Coufal, M. Wälchli, M. Torchia, D. Groth, G. Carlson, S. J. DeArmond, D. Westaway, and S. B. Prusiner, "Transgenic mice expressing hamster prion protein produce speciesspecifi c scrapie infectivity and amyloid plaques," Cell 59: 847-57 (1989).
-
(1989)
Cell
, vol.59
, pp. 847-857
-
-
Scott, M.1
Foster, D.2
Mirenda, C.3
Serban, D.4
Coufal, F.5
Wälchli, M.6
Torchia, M.7
Groth, D.8
Carlson, G.9
DeArmond, S.J.10
Westaway, D.11
Prusiner, S.B.12
-
106
-
-
0024820814
-
Transgenic mice expressing hamster prion protein produce speciesspecifi c scrapie infectivity and amyloid plaques
-
M. Scott, D. Foster, C. Mirenda, D. Serban, F. Coufal, M. Wälchli, M. Torchia, D. Groth, G. Carlson, S. J. DeArmond, D. Westaway, and S. B. Prusiner, "Transgenic mice expressing hamster prion protein produce speciesspecifi c scrapie infectivity and amyloid plaques," Cell 59: 847-57 (1989).
-
(1989)
Cell
, vol.59
, pp. 847-857
-
-
Scott, M.1
Foster, D.2
Mirenda, C.3
Serban, D.4
Coufal, F.5
Wälchli, M.6
Torchia, M.7
Groth, D.8
Carlson, G.9
DeArmond, S.J.10
Westaway, D.11
Prusiner, S.B.12
-
107
-
-
0025800143
-
A unifi ed theory of prion propagation
-
C. Weissmann, "A unifi ed theory of prion propagation," Nature 352: 679-83 (1991).
-
(1991)
Nature
, vol.352
, pp. 679-683
-
-
Weissmann, C.1
-
108
-
-
0026552043
-
Fatal familial insomnia, a prion disease with a mutation at codon 178 of the prion protein gene
-
R. Medori, H.-J. Tritschler, A. LeBlanc, F. Villare, V. Manetto, H. Y. Chen, R. Xue, S. Leal, P. Montagna, P. Cortelli, P. Tinuper, P. Avoni, M. Mochi, A. Baruzzi, J. J. Hauw, J. Ott, E. Lugaresi, L. Autilio-Gambetti, and P. Gambetti, "Fatal familial insomnia, a prion disease with a mutation at codon 178 of the prion protein gene," N. Engl. J. Med. 326: 444-49 (1992).
-
(1992)
N. Engl. J. Med
, vol.326
, pp. 444-449
-
-
Medori, R.1
Tritschler, H.-J.2
LeBlanc, A.3
Villare, F.4
Manetto, V.5
Chen, H.Y.6
Xue, R.7
Leal, S.8
Montagna, P.9
Cortelli, P.10
Tinuper, P.11
Avoni, P.12
Mochi, M.13
Baruzzi, A.14
Hauw, J.J.15
Ott, J.16
Lugaresi, E.17
Autilio-Gambetti, L.18
Gambetti, P.19
-
109
-
-
0025287947
-
Codon 129 changes in the prion protein gene in Caucasians
-
F. Owen, M. Poulter, J. Collinge, and T. J. Crow, "Codon 129 changes in the prion protein gene in Caucasians," Am. J. Hum. Genet. 46: 1215-16 (1990).
-
(1990)
Am. J. Hum. Genet
, vol.46
, pp. 1215-1216
-
-
Owen, F.1
Poulter, M.2
Collinge, J.3
Crow, T.J.4
-
110
-
-
0025944507
-
Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy
-
B. W. Caughey, A. Dong, K. S. Bhat, D. Ernst, S. F. Hayes, and W. S. Caughey, "Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy," Biochemistry 30: 7672-80 (1991).
-
(1991)
Biochemistry
, vol.30
, pp. 7672-7680
-
-
Caughey, B.W.1
Dong, A.2
Bhat, K.S.3
Ernst, D.4
Hayes, S.F.5
Caughey, W.S.6
-
111
-
-
0027074458
-
Purifi cation and properties of the cellular prion protein from Syrian hamster brain
-
K.-M. Pan, N. Stahl, and S. B. Prusiner, "Purifi cation and properties of the cellular prion protein from Syrian hamster brain," Protein Sci. 1: 1343-52 (1992).
-
(1992)
Protein Sci
, vol.1
, pp. 1343-1352
-
-
Pan, K.-M.1
Stahl, N.2
Prusiner, S.B.3
-
112
-
-
0027332116
-
Conversion of α-helices into β-sheets features in the formation of the scrapie prion proteins
-
K.-M. Pan, M. Baldwin, J. Nguyen, M. Gasset, A. Serban, D. Groth, I. Mehlhorn, Z. Huang, R. J. Fletterick, F. E. Cohen, and S. B. Prusiner, "Conversion of α-helices into β-sheets features in the formation of the scrapie prion proteins," Proc. Natl. Acad. Sci. USA 90: 10962-66 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10962-10966
-
-
Pan, K.-M.1
Baldwin, M.2
Nguyen, J.3
Gasset, M.4
Serban, A.5
Groth, D.6
Mehlhorn, I.7
Huang, Z.8
Fletterick, R.J.9
Cohen, F.E.10
Prusiner, S.B.11
-
113
-
-
84903229053
-
Transgenic animals lacking prion proteins
-
United States #5,698,763
-
C. Weissmann, H. Büeler, M. Aguet, M. Fischer, and A. Sailer. "Transgenic animals lacking prion proteins." United States #5,698,763; 1997.
-
-
-
Weissmann, C.1
Büeler, H.2
Aguet, M.3
Fischer, M.4
Sailer, A.5
-
114
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
H. Büeler, M. Fisher, Y. Lang, H. Bluethmann, H.-P. Lipp, S. J. DeArmond, S. B. Prusiner, M. Aguet, and C. Weissmann, "Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein," Nature 356: 577-82 (1992).
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Büeler, H.1
Fisher, M.2
Lang, Y.3
Bluethmann, H.4
Lipp, H.-P.5
DeArmond, S.J.6
Prusiner, S.B.7
Aguet, M.8
Weissmann, C.9
-
115
-
-
33845681207
-
Discovering DNA encodes heredity and prions are infectious proteins
-
S. B. Prusiner and M. McCarty, "Discovering DNA encodes heredity and prions are infectious proteins," Annu. Rev. Genet. 40: 25-45 (2006).
-
(2006)
Annu. Rev. Genet
, vol.40
, pp. 25-45
-
-
Prusiner, S.B.1
McCarty, M.2
-
116
-
-
84903237418
-
Viruses or prions: An old medical debate still rages
-
October 4
-
G. Kolata, "Viruses or prions: An old medical debate still rages," New York Times, October 4, 1994.
-
(1994)
New York Times
-
-
Kolata, G.1
-
117
-
-
0002694792
-
Unconventional viruses causing subacute spongiform encephalopathies
-
ed. B. N. Fields, D. M. Knipe, R. M. Chanock, J. L. Melnick, B. Roizman, and R. E. Shope (Raven, New York)
-
D. C. Gajdusek, "Unconventional viruses causing subacute spongiform encephalopathies," in Virology, ed. B. N. Fields, D. M. Knipe, R. M. Chanock, J. L. Melnick, B. Roizman, and R. E. Shope (Raven, New York, 1985) 1519-57.
-
(1985)
In Virology
, pp. 1519-1557
-
-
Gajdusek, D.C.1
-
118
-
-
0037476130
-
Scrapie-virus or viroid: The case for a virus
-
ed. A. Boese (Verlag Chemie, Weinheim)
-
R. G. Rohwer and D. C. Gajdusek, "Scrapie-virus or viroid: the case for a virus," in Search for the Cause of Multiple Sclerosis and Other Chronic Diseases of the Central Ner vous System, ed. A. Boese (Verlag Chemie, Weinheim, 1980), 333-55.
-
(1980)
In Search for the Cause of Multiple Sclerosis and Other Chronic Diseases of the Central Ner vous System
, pp. 333-355
-
-
Rohwer, R.G.1
Gajdusek, D.C.2
-
120
-
-
0342951746
-
A new variant of Creutzfeldt-Jakob disease in the UK
-
R. G. Will, J. W. Ironside, M. Zeidler, S. N. Cousens, K. Estibeiro, A. Alperovitch, S. Poser, M. Pocchiari, A. Hofman, and P. G. Smith, "A new variant of Creutzfeldt-Jakob disease in the UK," Lancet 347: 921-25 (1996).
-
(1996)
Lancet
, vol.347
, pp. 921-925
-
-
Will, R.G.1
Ironside, J.W.2
Zeidler, M.3
Cousens, S.N.4
Estibeiro, K.5
Alperovitch, A.6
Poser, S.7
Pocchiari, M.8
Hofman, A.9
Smith, P.G.10
-
121
-
-
9544238083
-
Transmission dynamics and epidemiology of BSE in British cattle
-
R. M. Anderson, C. A. Donnelly, N. M. Ferguson, M. E. J. Wool house, C. J. Watt, H. J. Udy, S. MaWhinney, S. P. Dunstan, T. R. E. Southwood, J. W. Wilesmith, J. B. M. Ryan, L. J. Hoinville, J. E. Hillerton, A. R. Austin, and G. A. H. Wells, "Transmission dynamics and epidemiology of BSE in British cattle," Nature 382: 779-88 (1996).
-
(1996)
Nature
, vol.382
, pp. 779-788
-
-
Anderson, R.M.1
Donnelly, C.A.2
Ferguson, N.M.3
Wool House, M.E.J.4
Watt, C.J.5
Udy, H.J.6
MaWhinney, S.7
Dunstan, S.P.8
Southwood, T.R.E.9
Wilesmith, J.W.10
Ryan, J.B.M.11
Hoinville, L.J.12
Hillerton, J.E.13
Austin, A.R.14
Wells, G.A.H.15
-
122
-
-
0023669586
-
A novel progressive spongiform encephalopathy in cattle
-
G. A. H. Wells, A. C. Scott, C. T. Johnson, R. F. Gunning, R. D. Hancock, M. Jeff rey, M. Dawson, and R. Bradley, "A novel progressive spongiform encephalopathy in cattle," Vet. Rec. 121: 419-20 (1987).
-
(1987)
Vet. Rec
, vol.121
, pp. 419-420
-
-
Wells, G.A.H.1
Scott, A.C.2
Johnson, C.T.3
Gunning, R.F.4
Hancock, R.D.5
Jeffrey, M.6
Dawson, M.7
Bradley, R.8
-
123
-
-
0024296039
-
Fibrils from brains of cows with new cattle disease contain scrapie-associated protein
-
J. Hope, L. J. D. Reekie, N. Hunter, G. Multhaup, K. Beyreuther, H. White, A. C. Scott, M. J. Stack, M. Dawson, and G. A. H. Wells, "Fibrils from brains of cows with new cattle disease contain scrapie-associated protein," Nature 336: 390-92 (1988).
-
(1988)
Nature
, vol.336
, pp. 390-392
-
-
Hope, J.1
Reekie, L.J.D.2
Hunter, N.3
Multhaup, G.4
Beyreuther, K.5
White, H.6
Scott, A.C.7
Stack, M.J.8
Dawson, M.9
Wells, G.A.H.10
-
124
-
-
0026412979
-
Bovine spongiform encephalopathy: Epidemiologic studies on the origin
-
J. W. Wilesmith, J. B. M. Ryan, and M. J. Atkinson, "Bovine spongiform encephalopathy: Epidemiologic studies on the origin," Vet. Rec. 128: 199-203 (1991).
-
(1991)
Vet. Rec
, vol.128
, pp. 199-203
-
-
Wilesmith, J.W.1
Ryan, J.B.M.2
Atkinson, M.J.3
-
125
-
-
0018215610
-
Unusual re sis tance to ionizing radiation of the viruses of kuru, Creutzfeld-Jakob disease, and scrapie
-
C. J. Gibbs, Jr., D. C. Gajdusek, and R. Latarjet, "Unusual re sis tance to ionizing radiation of the viruses of kuru, Creutzfeld-Jakob disease, and scrapie," Proc. Nat. Acad. Sci. 75: 6268-70 (1978).
-
(1978)
Proc. Nat. Acad. Sci
, vol.75
, pp. 6268-6270
-
-
Gibbs, C.J.1
Gajdusek, D.C.2
Latarjet, R.3
-
126
-
-
0021998646
-
Creutzfeldt-Jakob disease prion proteins in human brains
-
J. M. Bockman, D. T. Kingsbury, M. P. McKinley, P. E. Bendheim, and S. B. Prusiner, "Creutzfeldt-Jakob disease prion proteins in human brains," N. Engl. J. Med. 312: 73-78 (1985).
-
(1985)
N. Engl. J. Med
, vol.312
, pp. 73-78
-
-
Bockman, J.M.1
Kingsbury, D.T.2
McKinley, M.P.3
Bendheim, P.E.4
Prusiner, S.B.5
-
127
-
-
0022363507
-
Creutzfeldt-Jakob disease in a young adult with idiopathic hypopituitarism. Possible relation to the administration of cadaveric human growth hormone
-
T. K. Koch, B. O. Berg, S. J. DeArmond, and R. F. Gravina, "Creutzfeldt-Jakob disease in a young adult with idiopathic hypopituitarism. Possible relation to the administration of cadaveric human growth hormone," N. Engl. J. Med. 313: 731-33 (1985).
-
(1985)
N. Engl. J. Med
, vol.313
, pp. 731-733
-
-
Koch, T.K.1
Berg, B.O.2
DeArmond, S.J.3
Gravina, R.F.4
-
128
-
-
84961034678
-
Scrapie produced experimentally in goats with special reference to the clinical syndrome
-
I. H. Pattison and G. C. Millson, "Scrapie produced experimentally in goats with special reference to the clinical syndrome," J. Comp. Pathol. 71: 101-8 (1961).
-
(1961)
J. Comp. Pathol
, vol.71
, pp. 101-108
-
-
Pattison, I.H.1
Millson, G.C.2
-
129
-
-
0025910229
-
Molecular biology of prion diseases
-
S. B. Prusiner, "Molecular biology of prion diseases," Science, New Series 252: 1515-22 (1991).
-
(1991)
Science, New Series
, vol.252
, pp. 1515-1522
-
-
Prusiner, S.B.1
-
130
-
-
0026012059
-
Epidemiological and experimental studies on a new incident of transmissible mink encephalopathy
-
R. F. Marsh, R. A. Bessen, S. Lehmann, and G. R. Hartsough, "Epidemiological and experimental studies on a new incident of transmissible mink encephalopathy," J. Gen. Virol. 72: 589-94 (1991).
-
(1991)
J. Gen. Virol
, vol.72
, pp. 589-594
-
-
Marsh, R.F.1
Bessen, R.A.2
Lehmann, S.3
Hartsough, G.R.4
-
131
-
-
0026558780
-
Identifi cation of two biologically distinct strains of transmissible mink encephalopathy in hamsters
-
R. A. Bessen and R. F. Marsh, "Identifi cation of two biologically distinct strains of transmissible mink encephalopathy in hamsters," J. Gen. Virol. 73: 329-34 (1992).
-
(1992)
J. Gen. Virol
, vol.73
, pp. 329-334
-
-
Bessen, R.A.1
Marsh, R.F.2
-
132
-
-
12644272790
-
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity
-
G. C. Telling, P. Parchi, S. J. DeArmond, P. Cortelli, P. Montagna, R. Gabizon, J. Mastrianni, E. Lugaresi, P. Gambetti, and S. B. Prusiner, "Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity," Science 274: 2079-82 (1996).
-
(1996)
Science
, vol.274
, pp. 2079-2082
-
-
Telling, G.C.1
Parchi, P.2
DeArmond, S.J.3
Cortelli, P.4
Montagna, P.5
Gabizon, R.6
Mastrianni, J.7
Lugaresi, E.8
Gambetti, P.9
Prusiner, S.B.10
-
133
-
-
0033609313
-
Prion protein conformation in a patient with sporadic fatal insomnia
-
J. A. Mastrianni, R. Nixon, R. Layzer, G. C. Telling, D. Han, S. J. DeArmond, and S. B. Prusiner, "Prion protein conformation in a patient with sporadic fatal insomnia," N. Engl. J. Med. 340: 1630-38 (1999).
-
(1999)
N. Engl. J. Med
, vol.340
, pp. 1630-1638
-
-
Mastrianni, J.A.1
Nixon, R.2
Layzer, R.3
Telling, G.C.4
Han, D.5
DeArmond, S.J.6
Prusiner, S.B.7
-
134
-
-
26244461742
-
Prion clearance in bigenic mice
-
J. G. Safar, S. J. DeArmond, K. Kociuba, C. Deering, S. Didorenko, E. Bouzamondo-Bernstein, S. B. Prusiner, and P. Tremblay, "Prion clearance in bigenic mice," J. Gen. Virol. 86: 2913-23 (2005).
-
(2005)
J. Gen. Virol
, vol.86
, pp. 2913-2923
-
-
Safar, J.G.1
DeArmond, S.J.2
Kociuba, K.3
Deering, C.4
Didorenko, S.5
Bouzamondo-Bernstein, E.6
Prusiner, S.B.7
Tremblay, P.8
-
135
-
-
4243331887
-
the action of monochromatic ultraviolet light on proteins
-
R. Setlow and B. Doyle, "the action of monochromatic ultraviolet light on proteins," Biochim. Biophys. Acta 24: 27-41 (1957).
-
(1957)
Biochim. Biophys. Acta
, vol.24
, pp. 27-41
-
-
Setlow, R.1
Doyle, B.2
-
136
-
-
0036128896
-
Shedding light on proteins, nucleic acids, cells, humans, and fish
-
R. B. Setlow, "Shedding light on proteins, nucleic acids, cells, humans, and fi sh," Mutat. Res. 511: 1-14 (2002).
-
(2002)
Mutat. Res
, vol.511
, pp. 1-14
-
-
Setlow, R.B.1
-
138
-
-
0032514707
-
Doxycyline control of prion protein transgene expression modulates prion disease in mice
-
P. Tremblay, Z. Meiner, M. Galou, C. Heinrich, C. Petromilli, T. Lisse, J. Cayetano, M. Torchia, W. Mobley, H. Bujard, S. J. DeArmond, and S. B. Prusiner, "Doxycyline control of prion protein transgene expression modulates prion disease in mice," Proc. Natl. Acad. Sci. USA 95: 12580-85 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12580-12585
-
-
Tremblay, P.1
Meiner, Z.2
Galou, M.3
Heinrich, C.4
Petromilli, C.5
Lisse, T.6
Cayetano, J.7
Torchia, M.8
Mobley, W.9
Bujard, H.10
DeArmond, S.J.11
Prusiner, S.B.12
-
139
-
-
0014190760
-
Nature of the scrapie agent: Self-replication and scrapie
-
J. S. Griffith, "Nature of the scrapie agent: Self-replication and scrapie," Nature 215: 1043-44 (1967).
-
(1967)
Nature
, vol.215
, pp. 1043-1044
-
-
Griffith, J.S.1
-
140
-
-
52649167285
-
Pathological science
-
December 1
-
R. Rhodes, "Pathological science," New Yorker, December 1, 1997, pp. 54-59.
-
(1997)
New Yorker
, pp. 54-59
-
-
Rhodes, R.1
-
141
-
-
84903229054
-
Nobel gas
-
October 11
-
G. Taubes, "Nobel gas," Slate, October 11, 1997, http://www.slate.com/articles/news_and_politics/hey_wait_a_minute/1997/10/nobel_gas.single.html.
-
(1997)
Slate
-
-
Taubes, G.1
-
143
-
-
84903229055
-
Against jesters who defame and insult (Les Prix Nobel Lecture)
-
ed. T. Frängsmyr (Almqvist and Wiksell International, Stockholm)
-
D. Fo, "Against jesters who defame and insult (Les Prix Nobel Lecture)," in Les Prix Nobel, ed. T. Frängsmyr (Almqvist and Wiksell International, Stockholm, 1997), 381-406.
-
(1997)
In Les Prix Nobel
, pp. 381-406
-
-
Fo, D.1
-
146
-
-
84862620376
-
A unifying role for prions in neurodegenerative diseases
-
S. B. Prusiner, "A unifying role for prions in neurodegenerative diseases," Science 336: 1511-13 (2012).
-
(2012)
Science
, vol.336
, pp. 1511-1513
-
-
Prusiner, S.B.1
-
147
-
-
84888594143
-
Biology and ge ne tics of prions causing neurodegeneration
-
S. B. Prusiner, "Biology and ge ne tics of prions causing neurodegeneration," Annu. Rev. Genet. 47: 601-23 (2013).
-
(2013)
Annu. Rev. Genet
, vol.47
, pp. 601-623
-
-
Prusiner, S.B.1
-
148
-
-
0035902194
-
Shattuck Lecture-Neurodegenerative diseases and prions
-
S. B. Prusiner, "Shattuck Lecture-Neurodegenerative diseases and prions," N. Engl. J. Med. 344: 1516-26 (2001).
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 1516-1526
-
-
Prusiner, S.B.1
-
149
-
-
84903229051
-
Biology and ge ne tics of prions causing neurodegeneration
-
Prusiner, "Biology and ge ne tics of prions causing neurodegeneration."
-
-
-
Prusiner1
-
150
-
-
33645808672
-
Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease
-
R. W. Mahley, K. H. Weisgraber, and Y. Huang, "Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease," Proc. Natl. Acad. Sci. USA 103: 5644-51 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 5644-5651
-
-
Mahley, R.W.1
Weisgraber, K.H.2
Huang, Y.3
-
151
-
-
84858074593
-
CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion
-
J. M. Lee, E. M. Ramos, J. H. Lee, T. Gillis, J. S. Mysore, M. R. Hayden, S. C. Warby, P. Morrison, M. Nance, C. A. Ross, R. L. Margolis, F. Squitieri, S. Orobello, S. Di Donato, E. Gomez-Tortosa, C. Ayuso, O. Suchowersky, R. J. Trent, E. McCusker, A. Novelletto, M. Frontali, R. Jones, T. Ashizawa, S. Frank, M. H. Saint-Hilaire, S. M. Hersch, H. D. Rosas, D. Lucente, M. B. Harrison, A. Zanko, R. K. Abramson, K. Marder, J. Sequeiros, J. S. Paulsen, G. B. Landwehrmeyer, R. H. Myers, M. E. Macdonald, and J. F. Gusella, "CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion," Neurology 78: 690-95 (2012).
-
(2012)
Neurology
, vol.78
, pp. 690-695
-
-
Lee, J.M.1
Ramos, E.M.2
Lee, J.H.3
Gillis, T.4
Mysore, J.S.5
Hayden, M.R.6
Warby, S.C.7
Morrison, P.8
Nance, M.9
Ross, C.A.10
Margolis, R.L.11
Squitieri, F.12
Orobello, S.13
Di Donato, S.14
Gomez-Tortosa, E.15
Ayuso, C.16
Suchowersky, O.17
Trent, R.J.18
McCusker, E.19
Novelletto, A.20
Frontali, M.21
Jones, R.22
Ashizawa, T.23
Frank, S.24
Saint-Hilaire, M.H.25
Hersch, S.M.26
Rosas, H.D.27
Lucente, D.28
Harrison, M.B.29
Zanko, A.30
Abramson, R.K.31
Marder, K.32
Sequeiros, J.33
Paulsen, J.S.34
Landwehrmeyer, G.B.35
Myers, R.H.36
Macdonald, M.E.37
Gusella, J.F.38
more..
-
152
-
-
59649095699
-
Cytoplasmic penetration and per sis tent infection of mammalian cells by polyglutamine aggregates
-
P. H. Ren, J. E. Lauckner, I. Kachirskaia, J. E. Heuser, R. Melki, and R. R. Kopito, "Cytoplasmic penetration and per sis tent infection of mammalian cells by polyglutamine aggregates," Nat. Cell Biol. 11: 219-25 (2009).
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 219-225
-
-
Ren, P.H.1
Lauckner, J.E.2
Kachirskaia, I.3
Heuser, J.E.4
Melki, R.5
Kopito, R.R.6
-
153
-
-
0029940510
-
Pattern of brain destruction in Parkinson's and Alzheimer's diseases
-
H. Braak, E. Braak, D. Yilmazer, R. A. de Vos, E. N. Jansen, and J. Bohl, "Pattern of brain destruction in Parkinson's and Alzheimer's diseases," J. Neural Transm. 103: 455-90 (1996).
-
(1996)
J. Neural Transm
, vol.103
, pp. 455-490
-
-
Braak, H.1
Braak, E.2
Yilmazer, D.3
De Vos, R.A.4
Jansen, E.N.5
Bohl, J.6
-
154
-
-
64149093013
-
Neurodegenerative diseases target large-scale human brain networks
-
W. W. Seeley, R. K. Crawford, J. Zhou, B. L. Miller, and M. D. Greicius, "Neurodegenerative diseases target large-scale human brain networks," Neuron 62: 42-52 (2009).
-
(2009)
Neuron
, vol.62
, pp. 42-52
-
-
Seeley, W.W.1
Crawford, R.K.2
Zhou, J.3
Miller, B.L.4
Greicius, M.D.5
-
155
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
A. de Calignon, M. Polydoro, M. Suarez-Calvet, C. William, D. H. Adamowicz, K. J. Kopeikina, R. Pitstick, N. Sahara, K. H. Ashe, G. A. Carlson, T. L. Spires-Jones, and B. T. Hyman, "Propagation of tau pathology in a model of early Alzheimer's disease," Neuron 73: 685-97 (2012).
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
De Calignon, A.1
Polydoro, M.2
Suarez-Calvet, M.3
William, C.4
Adamowicz, D.H.5
Kopeikina, K.J.6
Pitstick, R.7
Sahara, N.8
Ashe, K.H.9
Carlson, G.A.10
Spires-Jones, T.L.11
Hyman, B.T.12
-
156
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
L. Liu, V. Drouet, J. W. Wu, M. P. Witter, S. A. Small, C. Clelland, and K. Duff, "Trans-synaptic spread of tau pathology in vivo," PLoS ONE 7: e31302 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
Duff, K.7
-
157
-
-
0028308104
-
[URE3] as an altered URE2 protein: Evidence for a prion analog in Saccharomyces cerevisiae
-
R. B. Wickner, "[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae," Science 264: 566-69 (1994).
-
(1994)
Science
, vol.264
, pp. 566-569
-
-
Wickner, R.B.1
-
158
-
-
33747878233
-
Very long term studies of the seeding of beta-amyloidosis in primates
-
R. M. Ridley, H. F. Baker, C. P. Windle, and R. M. Cummings, "Very long term studies of the seeding of beta-amyloidosis in primates," J. Neural Transm. 113: 1243-51 (2006).
-
(2006)
J. Neural Transm
, vol.113
, pp. 1243-1251
-
-
Ridley, R.M.1
Baker, H.F.2
Windle, C.P.3
Cummings, R.M.4
-
159
-
-
33749020837
-
Exogenous induction of ce re bral betaamyloidogenesis is governed by agent and host
-
M. Meyer-Luehmann, J. Coomaraswamy, T. Bolmont, S. Kaeser, C. Schaefer, E. Kilger, A. Neuenschwander, D. Abramowski, P. Frey, A. L. Jaton, J. M. Vigouret, P. Paganetti, D. M. Walsh, P. M. Mathews, J. Ghiso, M. Staufenbiel, L. C. Walker, and M. Jucker, "Exogenous induction of ce re bral betaamyloidogenesis is governed by agent and host," Science 313: 1781-84 (2006).
-
(2006)
Science
, vol.313
, pp. 1781-1784
-
-
Meyer-Luehmann, M.1
Coomaraswamy, J.2
Bolmont, T.3
Kaeser, S.4
Schaefer, C.5
Kilger, E.6
Neuenschwander, A.7
Abramowski, D.8
Frey, P.9
Jaton, A.L.10
Vigouret, J.M.11
Paganetti, P.12
Walsh, D.M.13
Mathews, P.M.14
Ghiso, J.15
Staufenbiel, M.16
Walker, L.C.17
Jucker, M.18
-
160
-
-
69149098707
-
Induction of ce re bral β-amyloidosis: Intrace re bral versus systemic Aβ inoculation
-
Y. S. Eisele, T. Bolmont, M. Heikenwalder, F. Langer, L. H. Jacobson, Z. X. Yan, K. Roth, A. Aguzzi, M. Staufenbiel, L. C. Walker, and M. Jucker, "Induction of ce re bral β-amyloidosis: Intrace re bral versus systemic Aβ inoculation," Proc. Natl. Acad. Sci. USA 106: 12926-31 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12926-12931
-
-
Eisele, Y.S.1
Bolmont, T.2
Heikenwalder, M.3
Langer, F.4
Jacobson, L.H.5
Yan, Z.X.6
Roth, K.7
Aguzzi, A.8
Staufenbiel, M.9
Walker, L.C.10
Jucker, M.11
-
161
-
-
84857145664
-
Exogenous seeding of ce re bral beta-amyloid deposition in betaAPP-transgenic rats
-
R. F. Rosen, J. J. Fritz, J. Dooyema, A. F. Cintron, T. Hamaguchi, J. J. Lah, H. Levine, 3rd, M. Jucker, and L. C. Walker, "Exogenous seeding of ce re bral beta-amyloid deposition in betaAPP-transgenic rats," J. Neurochem. 120: 660-66 (2012).
-
(2012)
J. Neurochem
, vol.120
, pp. 660-666
-
-
Rosen, R.F.1
Fritz, J.J.2
Dooyema, J.3
Cintron, A.F.4
Hamaguchi, T.5
Lah, J.J.6
Levine, H.7
Jucker, M.8
Walker, L.C.9
-
162
-
-
84870067233
-
De novo induction of amyloid-β deposition in vivo
-
R. Morales, C. Duran-Aniotz, J. Castilla, L. D. Estrada, and C. Soto, "De novo induction of amyloid-β deposition in vivo," Mol. Psychiatry 1347-53 (2012).
-
(2012)
Mol. Psychiatry
, pp. 1347-1353
-
-
Morales, R.1
Duran-Aniotz, C.2
Castilla, J.3
Estrada, L.D.4
Soto, C.5
-
163
-
-
70349298441
-
Mea sur ing prions by bioluminescence imaging
-
G. Tamgüney, K. P. Francis, K. Giles, A. Lemus, S. J. DeArmond, and S. B. Prusiner, "Mea sur ing prions by bioluminescence imaging," Proc. Natl. Acad. Sci. USA 106: 15002-6 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 15002-15006
-
-
Tamgüney, G.1
Francis, K.P.2
Giles, K.3
Lemus, A.4
DeArmond, S.J.5
Prusiner, S.B.6
-
164
-
-
79952294595
-
Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease
-
J. C. Watts, K. Giles, S. K. Grillo, A. Lemus, S. J. DeArmond, and S. B. Prusiner, "Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease," Proc. Natl. Acad. Sci. USA 108: 2528-33 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 2528-2533
-
-
Watts, J.C.1
Giles, K.2
Grillo, S.K.3
Lemus, A.4
DeArmond, S.J.5
Prusiner, S.B.6
-
165
-
-
73949160065
-
Design and construction of diverse mammalian prior strains
-
D. W. Colby, K. Giles, G. Legname, H. Wille, I. V. Baskakov, S. J. DeArmond, and S. B. Prusiner, "Design and construction of diverse mammalian prior strains," Proc. Natl. Acad. Sci. USA 106:20417-22 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20417-20422
-
-
Colby, D.W.1
Giles, K.2
Legname, G.3
Wille, H.4
Baskakov, I.V.5
DeArmond, S.J.6
Prusiner, S.B.7
-
166
-
-
84863595757
-
Purifi ed and synthetic Alzheimer's amyloid beta (Aβ) prions
-
J. Stöhr, J. C. Watts, Z. L. Mensinger, A. Oehler, S. K. Grillo, S. J. DeArmond, S. B. Prusiner, and K. Giles, "Purifi ed and synthetic Alzheimer's amyloid beta (Aβ) prions," Proc. Natl. Acad. Sci. USA 109: 11025-30 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 11025-11030
-
-
Stöhr, J.1
Watts, J.C.2
Mensinger, Z.L.3
Oehler, A.4
Grillo, S.K.5
DeArmond, S.J.6
Prusiner, S.B.7
Giles, K.8
-
167
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
F. Clavaguera, T. Bolmont, R. A. Crowther, D. Abramowski, S. Frank, A. Probst, G. Fraser, A. K. Stalder, M. Beibel, M. Staufenbiel, M. Jucker, M. Goedert, and M. Tolnay, "Transmission and spreading of tauopathy in transgenic mouse brain," Nat. Cell Biol. 11: 909-13 (2009).
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
Jucker, M.11
Goedert, M.12
Tolnay, M.13
-
168
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
B. Frost, R. L. Jacks, and M. I. Diamond, "Propagation of tau misfolding from the outside to the inside of a cell," J. Biol. Chem. 284: 12845-52 (2009)
-
(2009)
J. Biol. Chem
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
169
-
-
79955441814
-
Seeding of normal tau by pathological tau conformers drives pathogenesis of Alzheimer-like tangles
-
J. L. Guo and V. M.-Y. Lee, "Seeding of normal tau by pathological tau conformers drives pathogenesis of Alzheimer-like tangles," J. Biol. Chem. 286: 15317-31 (2011).
-
(2011)
J. Biol. Chem
, vol.286
, pp. 15317-15331
-
-
Guo, J.L.1
Lee, V.M.-Y.2
-
170
-
-
0032543684
-
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
-
M. Hutton, C. L. Lendon, P. Rizzu, M. Baker, S. Froelich, H. Houlden, S. Pickering-Brown, S. Chakraverty, A. Isaacs, A. Grover, J. Hackett, J. Adamson, S. Lincoln, D. Dickson, P. Davies, R. C. Petersen, M. Stevens, E. de Graaff, E. Wauters, J. van Baren, M. Hillebrand, M. Joosse, J. M. Kwon, P. Nowotny, L. K. Che, J. Norton, J. C. Morris, L. A. Reed, J. Trojanowski, H. Basun, L. Lannfelt, M. Neystat, S. Fahn, F. Dark, T. Tannenberg, P. R. Dodd, N. Hayward, J. B. J. Kwok, P. R. Schofi eld, A. Andreadis, J. Snowden, D. Craufurd, D. Neary, F. Owen, B. A. Oostra, J. Hardy, A. Goate, J. van Swieten, D. Mann, T. Lynch, and P. Heutink, "Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17," Nature 393: 702-5 (1998).
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Petersen, R.C.16
Stevens, M.17
de Graaff, E.18
Wauters, E.19
van Baren, J.20
Hillebrand, M.21
Joosse, M.22
Kwon, J.M.23
Nowotny, P.24
Che, L.K.25
Norton, J.26
Morris, J.C.27
Reed, L.A.28
Trojanowski, J.29
Basun, H.30
Lannfelt, L.31
Neystat, M.32
Fahn, S.33
Dark, F.34
Tannenberg, T.35
Dodd, P.R.36
Hayward, N.37
Kwok, J.B.J.38
Schofield, P.R.39
Andreadis, A.40
Snowden, J.41
Craufurd, D.42
Neary, D.43
Owen, F.44
Oostra, B.A.45
Hardy, J.46
Goate, A.47
van Swieten, J.48
Mann, D.49
Lynch, T.50
Heutink, P.51
more..
-
171
-
-
80052938441
-
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
-
K. Rascovsky, J. R. Hodges, D. Knopman, M. F. Mendez, J. H. Kramer, J. Neuhaus, J. C. van Swieten, H. Seelaar, E. G. Dopper, C. U. Onyike, A. E. Hillis, K. A. Josephs, B. F. Boeve, A. Kertesz, W. W. Seeley, K. P. Rankin, J. K. Johnson, M. L. Gorno-Tempini, H. Rosen, C. E. Prioleau-Latham, A. Lee, C. M. Kipps, P. Lillo, O. Piguet, J. D. Rohrer, M. N. Rossor, J. D. Warren, N. C. Fox, D. Galasko, D. P. Salmon, S. E. Black, M. Mesulam, S. Weintraub, B. C. Dickerson, J. Diehl-Schmid, F. Pasquier, V. Deramecourt, F. Lebert, Y. Pijnenburg, T. W. Chow, F. Manes, J. Grafman, S. F. Cappa, M. Freedman, M. Grossman, and B. L. Miller, "Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia," Brain 134: 2456-77 (2011).
-
(2011)
Brain
, vol.134
, pp. 2456-2477
-
-
Rascovsky, K.1
Hodges, J.R.2
Knopman, D.3
Mendez, M.F.4
Kramer, J.H.5
Neuhaus, J.6
van Swieten, J.C.7
Seelaar, H.8
Dopper, E.G.9
Onyike, C.U.10
Hillis, A.E.11
Josephs, K.A.12
Boeve, B.F.13
Kertesz, A.14
Seeley, W.W.15
Rankin, K.P.16
Johnson, J.K.17
Gorno-Tempini, M.L.18
Rosen, H.19
Prioleau-Latham, C.E.20
Lee, A.21
Kipps, C.M.22
Lillo, P.23
Piguet, O.24
Rohrer, J.D.25
Rossor, M.N.26
Warren, J.D.27
Fox, N.C.28
Galasko, D.29
Salmon, D.P.30
Black, S.E.31
Mesulam, M.32
Weintraub, S.33
Dickerson, B.C.34
Diehl-Schmid, J.35
Pasquier, F.36
Deramecourt, V.37
Lebert, F.38
Pijnenburg, Y.39
Chow, T.W.40
Manes, F.41
Grafman, J.42
Cappa, S.F.43
Freedman, M.44
Grossman, M.45
Miller, B.L.46
more..
-
172
-
-
21744449747
-
Chronic traumatic encephalopathy in a National Football League player
-
B. I. Omalu, S. T. DeKosky, R. L. Minster, M. I. Kamboh, R. L. Hamilton, and C. H. Wecht, "Chronic traumatic encephalopathy in a National Football League player," Neurosurgery 57: 128-34 (2005).
-
(2005)
Neurosurgery
, vol.57
, pp. 128-134
-
-
Omalu, B.I.1
DeKosky, S.T.2
Minster, R.L.3
Kamboh, M.I.4
Hamilton, R.L.5
Wecht, C.H.6
-
173
-
-
84890448682
-
Absence of chronic traumatic encephalopathy in retired football players with multiple concussions and neurological symptomatology
-
L. N. Hazrati, M. C. Tartaglia, P. Diamandis, K. D. Davis, R. E. Green, R. Wennberg, J. C. Wong, L. Ezerins, and C. H. Tator, "Absence of chronic traumatic encephalopathy in retired football players with multiple concussions and neurological symptomatology," Front. Hum. Neurosci. 7: 222 (2013).
-
(2013)
Front. Hum. Neurosci
, vol.7
, pp. 222
-
-
Hazrati, L.N.1
Tartaglia, M.C.2
Diamandis, P.3
Davis, K.D.4
Green, R.E.5
Wennberg, R.6
Wong, J.C.7
Ezerins, L.8
Tator, C.H.9
-
174
-
-
68249157080
-
Chronic traumatic encephalopathy in athletes: Progressive tauopathy aft er repetitive head injury
-
A. C. McKee, R. C. Cantu, C. J. Nowinski, E. T. Hedley-Whyte, B. E. Gavett, A. E. Budson, V. E. Santini, H. S. Lee, C. A. Kubilus, and R. A. Stern, "Chronic traumatic encephalopathy in athletes: Progressive tauopathy aft er repetitive head injury," J. Neuropathol. Exp. Neurol. 68: 709-35 (2009).
-
(2009)
J. Neuropathol. Exp. Neurol
, vol.68
, pp. 709-735
-
-
McKee, A.C.1
Cantu, R.C.2
Nowinski, C.J.3
Hedley-Whyte, E.T.4
Gavett, B.E.5
Budson, A.E.6
Santini, V.E.7
Lee, H.S.8
Kubilus, C.A.9
Stern, R.A.10
-
175
-
-
82655180378
-
Chronic traumatic encephalopathy in an Iraqi war veteran with posttraumatic stress disorder who committed suicide
-
B. Omalu, J. L. Hammers, J. Bailes, R. L. Hamilton, M. I. Kamboh, G. Webster, and R. P. Fitzsimmons, "Chronic traumatic encephalopathy in an Iraqi war veteran with posttraumatic stress disorder who committed suicide," Neurosurg. Focus 31: E3 (2011).
-
(2011)
Neurosurg. Focus
, vol.31
-
-
Omalu, B.1
Hammers, J.L.2
Bailes, J.3
Hamilton, R.L.4
Kamboh, M.I.5
Webster, G.6
Fitzsimmons, R.P.7
-
176
-
-
84873352895
-
The spectrum of disease in chronic traumatic encephalopathy
-
A. C. McKee, T. D. Stein, C. J. Nowinski, R. A. Stern, D. H. Daneshvar, V. E. Alvarez, H. S. Lee, G. Hall, S. M. Wojtowicz, C. M. Baugh, D. O. Riley, C. A. Kubilus, K. A. Cormier, M. A. Jacobs, B. R. Martin, C. R. Abraham, T. Ikezu, R. R. Reichard, B. L. Wolozin, A. E. Budson, L. E. Goldstein, N. W. Kowall, and R. C. Cantu, "the spectrum of disease in chronic traumatic encephalopathy," Brain 136: 43-64 (2013).
-
(2013)
Brain
, vol.136
, pp. 43-64
-
-
McKee, A.C.1
Stein, T.D.2
Nowinski, C.J.3
Stern, R.A.4
Daneshvar, D.H.5
Alvarez, V.E.6
Lee, H.S.7
Hall, G.8
Wojtowicz, S.M.9
Baugh, C.M.10
Riley, D.O.11
Kubilus, C.A.12
Cormier, K.A.13
Jacobs, M.A.14
Martin, B.R.15
Abraham, C.R.16
Ikezu, T.17
Reichard, R.R.18
Wolozin, B.L.19
Budson, A.E.20
Goldstein, L.E.21
Kowall, N.W.22
Cantu, R.C.23
more..
-
177
-
-
38749111066
-
Mild traumatic brain injury in U.S. soldiers returning from Iraq
-
C. W. Hoge, D. McGurk, J. L. Th omas, A. L. Cox, C. C. Engel, and C. A. Castro, "Mild traumatic brain injury in U.S. soldiers returning from Iraq," N. Engl. J. Med. 358: 453-63 (2008).
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 453-463
-
-
Hoge, C.W.1
McGurk, D.2
Thomas, J.L.3
Cox, A.L.4
Engel, C.C.5
Castro, C.A.6
-
178
-
-
84903229057
-
Suicide rate among vets and active duty military jumps-now 22 a day
-
February 5
-
M. Haiken, "Suicide rate among vets and active duty military jumps-now 22 a day," Forbes, February 5, 2013.
-
(2013)
Forbes
-
-
Haiken, M.1
-
179
-
-
0029013727
-
Staging of Alzheimer's disease-related neurofi brillary changes
-
H. Braak and E. Braak, "Staging of Alzheimer's disease-related neurofi brillary changes," Neurobiol. Aging 16: 271-84 (1995).
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 271-284
-
-
Braak, H.1
Braak, E.2
-
180
-
-
11544279355
-
Diff usible, nonfi brillar ligands derived from A 1-42 are potent central ner vous system neurotoxins
-
M. P. Lambert, A. K. Barlow, B. A. Chromy, C. Edwards, R. Freed, M. Liosatos, T. E. Morgan, I. Rozovsky, B. Trommer, K. L. Viola, P. Wals, C. Zhang, C. E. Finch, G. A. Krafft, and W. L. Klein, "Diff usible, nonfi brillar ligands derived from A 1-42 are potent central ner vous system neurotoxins," Proc. Natl. Acad. Sci. USA 95: 6448-53 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
181
-
-
0037197836
-
Tau is essential to beta-amyloid-induced neurotoxicity
-
M. Rapoport, H. N. Dawson, L. I. Binder, M. P. Vitek, and A. Ferreira, "Tau is essential to beta-amyloid-induced neurotoxicity," Proc. Natl. Acad. Sci. USA 99: 6364-69 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
182
-
-
0026849947
-
Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofi brillary tangles
-
K. Hsiao, S. Dlouhy, M. R. Farlow, C. Cass, M. Da Costa, M. Conneally, M. E. Hodes, B. Ghetti, and S. B. Prusiner, "Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofi brillary tangles," Nat. Genet. 1: 68-71 (1992).
-
(1992)
Nat. Genet
, vol.1
, pp. 68-71
-
-
Hsiao, K.1
Dlouhy, S.2
Farlow, M.R.3
Cass, C.4
Da Costa, M.5
Conneally, M.6
Hodes, M.E.7
Ghetti, B.8
Prusiner, S.B.9
-
183
-
-
84887463054
-
A novel prion disease associated with diarrhea and autonomic neuropathy
-
S. Mead, S. Gandhi, J. Beck, D. Caine, D. Gallujipali, C. Carswell, H. Hyare, S. Joiner, H. Ayling, T. Lashley, J. M. Linehan, H. Al-Doujaily, B. Sharps, T. Revesz, M. K. Sandberg, M. M. Reilly, M. Koltzenburg, A. Forbes, P. Rudge, S. Brandner, J. D. Warren, J. D. Wadsworth, N. W. Wood, J. L. Holton, and J. Collinge, "A novel prion disease associated with diarrhea and autonomic neuropathy," N. Engl. J. Med. 369: 1904-14 (2013).
-
(2013)
N. Engl. J. Med
, vol.369
, pp. 1904-1914
-
-
Mead, S.1
Gandhi, S.2
Beck, J.3
Caine, D.4
Gallujipali, D.5
Carswell, C.6
Hyare, H.7
Joiner, S.8
Ayling, H.9
Lashley, T.10
Linehan, J.M.11
Al-Doujaily, H.12
Sharps, B.13
Revesz, T.14
Sandberg, M.K.15
Reilly, M.M.16
Koltzenburg, M.17
Forbes, A.18
Rudge, P.19
Brandner, S.20
Warren, J.D.21
Wadsworth, J.D.22
Wood, N.W.23
Holton, J.L.24
Collinge, J.25
more..
-
184
-
-
0036511037
-
Friedrich Heinrich Lewy (1885-1950) and his work
-
B. Holdorff, "Friedrich Heinrich Lewy (1885-1950) and his work," J. Hist. Neurosci. 11: 19-28 (2002).
-
(2002)
J. Hist. Neurosci
, vol.11
, pp. 19-28
-
-
Holdorff, B.1
-
185
-
-
43249110200
-
Lewy bodies in graft ed neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
-
J. Y. Li, E. Englund, J. L. Holton, D. Soulet, P. Hagell, A. J. Lees, T. Lashley, N. P. Quinn, S. Rehncrona, A. Bjorklund, H. Widner, T. Revesz, O. Lindvall, and P. Brundin, "Lewy bodies in graft ed neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation," Nat. Med. 14: 501-3 (2008).
-
(2008)
Nat. Med
, vol.14
, pp. 501-503
-
-
Li, J.Y.1
Englund, E.2
Holton, J.L.3
Soulet, D.4
Hagell, P.5
Lees, A.J.6
Lashley, T.7
Quinn, N.P.8
Rehncrona, S.9
Bjorklund, A.10
Widner, H.11
Revesz, T.12
Lindvall, O.13
Brundin, P.14
-
186
-
-
43249114934
-
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
-
J. H. Kordower, Y. Chu, R. A. Hauser, T. B. Freeman, and C. W. Olanow, "Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease," Nat. Med. 14: 504-6 (2008).
-
(2008)
Nat. Med
, vol.14
, pp. 504-506
-
-
Kordower, J.H.1
Chu, Y.2
Hauser, R.A.3
Freeman, T.B.4
Olanow, C.W.5
-
187
-
-
0030744876
-
Mutation in the α-synuclein gene identifi ed in families with Parkinson's disease
-
M. H. Polymeropoulos, C. Lavedan, E. Leroy, S. E. Ide, A. Dehejia, A. Dutra, B. Pike, H. Root, J. Rubenstein, R. Boyer, E. S. Stenroos, S. Chandrasekharappa, A. Athanassiadou, T. Papapetropoulos, W. G. Johnson, A. M. Lazzarini, R. C. Duvoisin, G. Di Iorio, L. I. Golbe, and R. L. Nussbaum, "Mutation in the α-synuclein gene identifi ed in families with Parkinson's disease," Science 276: 2045-47 (1997).
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
188
-
-
0030882856
-
α-Synuclein in Lewy bodies
-
M. G. Spillantini, M. L. Schmidt, V. M.-Y. Lee, J. Q. Trojanowski, R. Jakes, and M. Goedert, "α-Synuclein in Lewy bodies," Nature 388: 839-40 (1997).
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.-Y.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
190
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
H. Braak, K. Del Tredici, U. Rub, R. A. de Vos, E. N. Jansen Steur, and E. Braak, "Staging of brain pathology related to sporadic Parkinson's disease," Neurobiol. Aging 24: 197-211 (2003).
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
191
-
-
84863433677
-
Prion-like acceleration of a synucleinopathy in a transgenic mouse model
-
A.-L. Mougenot, S. Nicot, A. Bencsik, E. Morignat, J. Verchère, L. Lakhdar, S. Legastelois, and T. Baron, "Prion-like acceleration of a synucleinopathy in a transgenic mouse model," Neurobiol. Aging 33: 2225-28 (2012).
-
(2012)
Neurobiol. Aging
, vol.33
, pp. 2225-2228
-
-
Mougenot, A.-L.1
Nicot, S.2
Bencsik, A.3
Morignat, E.4
Verchère, J.5
Lakhdar, L.6
Legastelois, S.7
Baron, T.8
-
192
-
-
80053613574
-
Exogenous alpha-synuclein fi brils induce Lewy body pathology leading to synaptic dysfunction and neuron death
-
L. A. Volpicelli-Daley, K. C. Luk, T. P. Patel, S. A. Tanik, D. M. Riddle, A. Stieber, D. F. Meaney, J. Q. Trojanowski, and V. M. Lee, "Exogenous alpha-synuclein fi brils induce Lewy body pathology leading to synaptic dysfunction and neuron death," Neuron 72: 57-71 (2011).
-
(2011)
Neuron
, vol.72
, pp. 57-71
-
-
Volpicelli-Daley, L.A.1
Luk, K.C.2
Patel, T.P.3
Tanik, S.A.4
Riddle, D.M.5
Stieber, A.6
Meaney, D.F.7
Trojanowski, J.Q.8
Lee, V.M.9
-
193
-
-
84862609075
-
Intrace re bral inoculation of pathological a-synuclein initiates a rapidly progressive neurodegenerative a-synucleinopathy in mice
-
K. C. Luk, V. M. Kehm, B. Zhang, P. O'Brien, J. Q. Trojanowski, and V. M. Y. Lee, "Intrace re bral inoculation of pathological a-synuclein initiates a rapidly progressive neurodegenerative a-synucleinopathy in mice," J. Exp. Med. 209: 975-86 (2012).
-
(2012)
J. Exp. Med
, vol.209
, pp. 975-986
-
-
Luk, K.C.1
Kehm, V.M.2
Zhang, B.3
O'Brien, P.4
Trojanowski, J.Q.5
Lee, V.M.Y.6
-
194
-
-
84869109864
-
Pathological alpha-synuclein transmission initiates Parkinsonlike neurodegeneration in nontransgenic mice
-
K. C. Luk, V. Kehm, J. Carroll, B. Zhang, P. O'Brien, J. Q. Trojanowski, and V. M. Lee, "Pathological alpha-synuclein transmission initiates Parkinsonlike neurodegeneration in nontransgenic mice," Science 338: 949-53 (2012).
-
(2012)
Science
, vol.338
, pp. 949-953
-
-
Luk, K.C.1
Kehm, V.2
Carroll, J.3
Zhang, B.4
O'Brien, P.5
Trojanowski, J.Q.6
Lee, V.M.7
-
195
-
-
84876057762
-
Prion-like spreading of pathological alphasynuclein in brain
-
M. Masuda-Suzukake, T. Nonaka, M. Hosokawa, T. Oikawa, T. Arai, H. Akiyama, D. M. Mann, and M. Hasegawa, "Prion-like spreading of pathological alphasynuclein in brain," Brain 136: 1128-38 (2013).
-
(2013)
Brain
, vol.136
, pp. 1128-1138
-
-
Masuda-Suzukake, M.1
Nonaka, T.2
Hosokawa, M.3
Oikawa, T.4
Arai, T.5
Akiyama, H.6
Mann, D.M.7
Hasegawa, M.8
-
196
-
-
84888349390
-
Transmission of multiple system atrophy prions to transgenic mice
-
J. C. Watts, K. Giles, A. Oehler, L. T. Middleton, D. T. Dexter, S. M. Gentleman, S. J. DeArmond, and S. B. Prusiner, "Transmission of multiple system atrophy prions to transgenic mice," Proc. Natl. Acad. Sci. USA. 110: 19555-60 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 19555-19560
-
-
Watts, J.C.1
Giles, K.2
Oehler, A.3
Middleton, L.T.4
Dexter, D.T.5
Gentleman, S.M.6
DeArmond, S.J.7
Prusiner, S.B.8
-
197
-
-
79952743365
-
Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells
-
C. Münch, J. O'Brien, and A. Bertolotti, "Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells," Proc. Natl. Acad. Sci. USA 108: 3548-53 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 3548-3553
-
-
Münch, C.1
O'Brien, J.2
Bertolotti, A.3
-
198
-
-
80053652133
-
Intermolecular transmission of superoxide dismutase 1 misfolding in living cells
-
L. I. Grad, W. C. Guest, A. Yanai, E. Pokrishevsky, M. A. O'Neill, E. Gibbs, V. Semenchenko, M. Yousefi, D. S. Wishart, S. S. Plotkin, and N. R. Cashman, "Intermolecular transmission of superoxide dismutase 1 misfolding in living cells," Proc. Natl. Acad. Sci. USA 108: 16398-403 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 16398-16403
-
-
Grad, L.I.1
Guest, W.C.2
Yanai, A.3
Pokrishevsky, E.4
O'Neill, M.A.5
Gibbs, E.6
Semenchenko, V.7
Yousefi, M.8
Wishart, D.S.9
Plotkin, S.S.10
Cashman, N.R.11
-
199
-
-
75749134925
-
Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation
-
K. Si, Y. B. Choi, E. White-Grindley, A. Majumdar, and E. R. Kandel, "Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation," Cell 140: 421-35 (2010).
-
(2010)
Cell
, vol.140
, pp. 421-435
-
-
Si, K.1
Choi, Y.B.2
White-Grindley, E.3
Majumdar, A.4
Kandel, E.R.5
-
200
-
-
9444279617
-
Stress granule assembly is mediated by prion-like aggregation of TIA-1
-
N. Gilks, N. Kedersha, M. Ayodele, L. Shen, G. Stoecklin, L. M. Dember, and P. Anderson, "Stress granule assembly is mediated by prion-like aggregation of TIA-1," Mol. Biol. Cell. 15: 5383-98 (2004).
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 5383-5398
-
-
Gilks, N.1
Kedersha, N.2
Ayodele, M.3
Shen, L.4
Stoecklin, G.5
Dember, L.M.6
Anderson, P.7
-
201
-
-
79961133270
-
MAVS forms functional prionlike aggregates to activate and propagate antiviral innate immune response
-
F. Hou, L. Sun, H. Zheng, B. Skaug, Q. X. Jiang, and Z. J. Chen, "MAVS forms functional prionlike aggregates to activate and propagate antiviral innate immune response," Cell 146: 448-61 (2011).
-
(2011)
Cell
, vol.146
, pp. 448-461
-
-
Hou, F.1
Sun, L.2
Zheng, H.3
Skaug, B.4
Jiang, Q.X.5
Chen, Z.J.6
-
202
-
-
84883688262
-
Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
-
M. Jucker and L. C. Walker, "Self-propagation of pathogenic protein aggregates in neurodegenerative diseases," Nature 501: 45-51 (2013).
-
(2013)
Nature
, vol.501
, pp. 45-51
-
-
Jucker, M.1
Walker, L.C.2
-
203
-
-
84903229051
-
Biology and ge ne tics of prions causing neurodegeneration
-
Prusiner, "Biology and ge ne tics of prions causing neurodegeneration."
-
-
-
Prusiner1
-
204
-
-
0025244011
-
Transge ne tic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
-
S. B. Prusiner, M. Scott, D. Foster, K.-M. Pan, D. Groth, C. Mirenda, M. Torchia, S.-L. Yang, D. Serban, G. A. Carlson, P. C. Hoppe, D. Westaway, and S. J. DeArmond, "Transge ne tic studies implicate interactions between homologous PrP isoforms in scrapie prion replication," Cell 63: 673-86 (1990).
-
(1990)
Cell
, vol.63
, pp. 673-686
-
-
Prusiner, S.B.1
Scott, M.2
Foster, D.3
Pan, K.-M.4
Groth, D.5
Mirenda, C.6
Torchia, M.7
Yang, S.-L.8
Serban, D.9
Carlson, G.A.10
Hoppe, P.C.11
Westaway, D.12
DeArmond, S.J.13
-
205
-
-
0032888131
-
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
-
L. F. Lue, Y. M. Kuo, A. E. Roher, L. Brachova, Y. Shen, L. Sue, T. Beach, J. H. Kurth, R. E. Rydel, and J. Rogers, "Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease," Am. J. Pathol. 155: 853-62 (1999).
-
(1999)
Am. J. Pathol
, vol.155
, pp. 853-862
-
-
Lue, L.F.1
Kuo, Y.M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
Beach, T.7
Kurth, J.H.8
Rydel, R.E.9
Rogers, J.10
-
206
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in A lzheimer's disease
-
C. A. McLean, R. A. Cherny, F. W. Fraser, S. J. Fuller, M. J. Smith, K. Beyreuther, A. I. Bush, and C. L. Masters, "Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in A lzheimer's disease," Ann. Neurol. 46: 860-66 (1999).
-
(1999)
Ann. Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
207
-
-
79955955891
-
Soluble Abeta levels correlate with cognitive defi cits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease
-
W. Zhang, J. Hao, R. Liu, Z. Zhang, G. Lei, C. Su, J. Miao, and Z. Li, "Soluble Abeta levels correlate with cognitive defi cits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease," Behav. Brain Res. 222: 342-50 (2011).
-
(2011)
Behav. Brain Res
, vol.222
, pp. 342-350
-
-
Zhang, W.1
Hao, J.2
Liu, R.3
Zhang, Z.4
Lei, G.5
Su, C.6
Miao, J.7
Li, Z.8
-
208
-
-
84903006732
-
Purifi ed and synthetic Alzheimer's amyloid beta (Aβ) prions
-
Stöhr et al. "Purifi ed and synthetic Alzheimer's amyloid beta (Aβ) prions."
-
-
-
Stöhr1
-
209
-
-
84862868531
-
Spreading of neurodegenerative pathology via neuron-toneuron transmission of beta-amyloid
-
S. Nath, L. Agholme, F. R. Kurudenkandy, B. Granseth, J. Marcusson, and M. Hallbeck, "Spreading of neurodegenerative pathology via neuron-toneuron transmission of beta-amyloid," J. Neurosci. 32: 8767-77 (2012).
-
(2012)
J. Neurosci
, vol.32
, pp. 8767-8777
-
-
Nath, S.1
Agholme, L.2
Kurudenkandy, F.R.3
Granseth, B.4
Marcusson, J.5
Hallbeck, M.6
-
210
-
-
36348929457
-
Orally administered amyloidophilic compound is eff ective in prolonging the incubation periods of animals ce re brally infected with prion diseases in a prion strain-dependent manner
-
Y. Kawasaki, K. Kawagoe, C. J. Chen, K. Teruya, Y. Sakasegawa, and K. Doh-ura, "Orally administered amyloidophilic compound is eff ective in prolonging the incubation periods of animals ce re brally infected with prion diseases in a prion strain-dependent manner," J. Virol. 81: 12889-98 (2007).
-
(2007)
J. Virol
, vol.81
, pp. 12889-12898
-
-
Kawasaki, Y.1
Kawagoe, K.2
Chen, C.J.3
Teruya, K.4
Sakasegawa, Y.5
Doh-ura, K.6
-
211
-
-
84886032445
-
Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice
-
D. Lu, K. Giles, Z. Li, S. Rao, E. Dolghih, J. R. Gever, M. Geva, M. Elepano, A. Oehler, C. Bryant, A. R. Renslo, M. P. Jacobson, S. J. DeArmond, B. M. Silber, and S. B. Prusiner, "Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice," J. Pharmcol. Exp. therap. 347: 325-38 (2013).
-
(2013)
J. Pharmcol. Exp. therap
, vol.347
, pp. 325-338
-
-
Lu, D.1
Giles, K.2
Li, Z.3
Rao, S.4
Dolghih, E.5
Gever, J.R.6
Geva, M.7
Elepano, M.8
Oehler, A.9
Bryant, C.10
Renslo, A.R.11
Jacobson, M.P.12
DeArmond, S.J.13
Silber, B.M.14
Prusiner, S.B.15
-
212
-
-
84887099321
-
Drug re sis tance confounding prion therapeutics
-
D. B. Berry, D. Lu, M. Geva, J. C. Watts, S. Bhardwaj, A. Oehler, A. R. Renslo, S. J. DeArmond, S. B. Prusiner, and K. Giles, "Drug re sis tance confounding prion therapeutics," Proc. Natl. Acad. Sci. USA. 110: E4160-69 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
-
-
Berry, D.B.1
Lu, D.2
Geva, M.3
Watts, J.C.4
Bhardwaj, S.5
Oehler, A.6
Renslo, A.R.7
DeArmond, S.J.8
Prusiner, S.B.9
Giles, K.10
-
213
-
-
0021019026
-
Scrapie prions aggregate to form amyloid-like birefringent rods
-
S. B. Prusiner, M. P. McKinley, K. A. Bowman, D. C. Bolton, P. E. Bendheim, D. F. Groth, and G. G. Glenner, "Scrapie prions aggregate to form amyloid-like birefringent rods," Cell 35: 349-58 (1983).
-
(1983)
Cell
, vol.35
, pp. 349-358
-
-
Prusiner, S.B.1
McKinley, M.P.2
Bowman, K.A.3
Bolton, D.C.4
Bendheim, P.E.5
Groth, D.F.6
Glenner, G.G.7
-
214
-
-
0021344124
-
Some speculations about prions, amyloid, and Alzheimer's disease
-
S. B. Prusiner, "Some speculations about prions, amyloid, and Alzheimer's disease," N. Engl. J. Med. 310: 661-63 (1984).
-
(1984)
N. Engl. J. Med
, vol.310
, pp. 661-663
-
-
Prusiner, S.B.1
-
215
-
-
84903229058
-
Shattuck Lecture-Neurodegenerative diseases and prions
-
Prusiner, "Shattuck Lecture-Neurodegenerative diseases and prions".
-
-
-
Prusiner1
-
216
-
-
84862620376
-
A unifying role for prions in neurodegenerative diseases
-
S. B. Prusiner, "A unifying role for prions in neurodegenerative diseases," Science 336: 1511-13 (2012).
-
(2012)
Science
, vol.336
, pp. 1511-1513
-
-
Prusiner, S.B.1
-
217
-
-
84903229051
-
Biology and ge ne tics of prions causing neurodegeneration
-
Prusiner, "Biology and ge ne tics of prions causing neurodegeneration."
-
-
-
Prusiner1
-
219
-
-
1542332334
-
The method of multiple working hypotheses
-
T. C. Chamberlin, "The method of multiple working hypotheses," Science [Old Series] 15: 92-97 (1890).
-
(1890)
Science [Old Series]
, vol.15
, pp. 92-97
-
-
Chamberlin, T.C.1
-
220
-
-
84875789823
-
Monetary costs of dementia in the United States
-
M. D. Hurd, P. Martorell, A. Delavande, K. J. Mullen, and K. M. Langa, "Monetary costs of dementia in the United States," N. Engl. J. Med. 368: 1326-34 (2013).
-
(2013)
N. Engl. J. Med
, vol.368
, pp. 1326-1334
-
-
Hurd, M.D.1
Martorell, P.2
Delavande, A.3
Mullen, K.J.4
Langa, K.M.5
-
221
-
-
57449113401
-
Reporting dementia on the death certifi cates of nursing home residents dying withend-stage dementia
-
M. Wachterman, D. K. Kiely, and S. L. Mitchell, "Reporting dementia on the death certifi cates of nursing home residents dying withend-stage dementia," JAMA 300: 2608-10 (2008).
-
(2008)
JAMA
, vol.300
, pp. 2608-2610
-
-
Wachterman, M.1
Kiely, D.K.2
Mitchell, S.L.3
-
222
-
-
84897507292
-
The contribution of Alzheimer's disease to mortality in the United States
-
(in press)
-
B. D. James, S. E. Leurgans, L. E. Hebert, P. A. Scherr, K. Yaffe, and D. A. Bennett, "the contribution of Alzheimer's disease to mortality in the United States," Neurology (in press).
-
Neurology
-
-
James, B.D.1
Leurgans, S.E.2
Hebert, L.E.3
Scherr, P.A.4
Yaffe, K.5
Bennett, D.A.6
-
224
-
-
0017229879
-
Dementia
-
R. D. Terry, "Dementia," Arch. Neurol. 33: 1-4 (1976).
-
(1976)
Arch. Neurol
, vol.33
, pp. 1-4
-
-
Terry, R.D.1
-
225
-
-
0016942101
-
Editorial: The prevalence and malignancy of Alzheimer disease. A major killer
-
R. Katzman, "Editorial: The prevalence and malignancy of Alzheimer disease. A major killer," Arch. Neurol. 33: 217-28 (1976).
-
(1976)
Arch. Neurol
, vol.33
, pp. 217-228
-
-
Katzman, R.1
-
226
-
-
0022616654
-
Medical progress: Alzheimer's disease
-
R. Katzman, "Medical progress: Alzheimer's disease," N. Engl. J. Med. 314: 964-73 (1986).
-
(1986)
N. Engl. J. Med
, vol.314
, pp. 964-973
-
-
Katzman, R.1
-
227
-
-
0000174463
-
Ueber eine eigenartige Erkrankung der Hirnrinde
-
A. Alzheimer, "Ueber eine eigenartige Erkrankung der Hirnrinde," Cent. Nervenheilk. Psychiat. 30: 177-79 (1907).
-
(1907)
Cent. Nervenheilk. Psychiat
, vol.30
, pp. 177-179
-
-
Alzheimer, A.1
-
228
-
-
0021256895
-
Alzheimer's disease: Initial report of the purifi cation and characterization of a novel cerebrovascular amyloid protein
-
G. G. Glenner and C. W. Wong, "Alzheimer's disease: Initial report of the purifi cation and characterization of a novel cerebrovascular amyloid protein," Biochem. Biophys. Res. Commun. 120: 885-90 (1984).
-
(1984)
Biochem. Biophys. Res. Commun
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
229
-
-
0022257253
-
Mise en évidence immunologique de la protéine tau au niveau des lésions de dégénérescence neurofi brillaire de la maladie d'Alzheimer
-
J.-P. Brion, H. Passareiro, J. Nunez, and J. Flament-Durand, "Mise en évidence immunologique de la protéine tau au niveau des lésions de dégénérescence neurofi brillaire de la maladie d'Alzheimer," Arch. Biol. 95: 229-35 (1985).
-
(1985)
Arch. Biol
, vol.95
, pp. 229-235
-
-
Brion, J.-P.1
Passareiro, H.2
Nunez, J.3
Flament-Durand, J.4
-
230
-
-
0009364134
-
Microtubule-associated protein tau is a major antigenic component of paired helical fi laments in Alzheimer disease
-
K. S. Kosik, C. L. Joachim, and D. J. Selkoe, "Microtubule-associated protein tau is a major antigenic component of paired helical fi laments in Alzheimer disease," Proc. Natl. Acad. Sci. USA 83: 4044-48 (1986).
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4044-4048
-
-
Kosik, K.S.1
Joachim, C.L.2
Selkoe, D.J.3
-
231
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein (tau) in Alzheimer cytoskeletal pathology
-
I. Grundke-Iqbal, K. Iqbal, Y.-C. Tung, M. Quinlan, H. M. Wisniewski, and L. I. Binder, "Abnormal phosphorylation of the microtubule-associated protein (tau) in Alzheimer cytoskeletal pathology," Proc. Natl. Acad. Sci. USA 83: 4913-17 (1986).
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.-C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
232
-
-
1842685948
-
Neurofi brillary tangles of Alzheimer's disease share antigenic determinants with the axonal microtubuleassociated protein tau
-
J. G. Wood, S. S. Mirra, N. J. Pollock, and I. I. Binder, "Neurofi brillary tangles of Alzheimer's disease share antigenic determinants with the axonal microtubuleassociated protein tau," Proc. Natl. Acad. Sci. USA 83: 4040-43 (1986).
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4040-4043
-
-
Wood, J.G.1
Mirra, S.S.2
Pollock, N.J.3
Binder, I.I.4
-
235
-
-
0024317904
-
Prevalence of Alzheimer's disease in a community population of older persons-Higher than previously reported
-
D. A. Evans, H. H. Funkenstein, M. S. Albert, P. A. Scherr, N. R. Cook, M. J. Chown, L. E. Hebert, C. H. Hennekens, and J. O. Taylor, "Prevalence of Alzheimer's disease in a community population of older persons-Higher than previously reported," JAMA 10: 2551-56 (1989).
-
(1989)
JAMA
, vol.10
, pp. 2551-2556
-
-
Evans, D.A.1
Funkenstein, H.H.2
Albert, M.S.3
Scherr, P.A.4
Cook, N.R.5
Chown, M.J.6
Hebert, L.E.7
Hennekens, C.H.8
Taylor, J.O.9
-
236
-
-
38749111066
-
Mild traumatic brain injury in U.S. soldiers returning from Iraq
-
C. W. Hoge, D. McGurk, J. L. Thomas, A. L. Cox, C. C. Engel, and C. A. Castro, "Mild traumatic brain injury in U.S. soldiers returning from Iraq," N. Engl. J. Med. 358: 453-63 (2008).
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 453-463
-
-
Hoge, C.W.1
McGurk, D.2
Thomas, J.L.3
Cox, A.L.4
Engel, C.C.5
Castro, C.A.6
-
237
-
-
84883688262
-
Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
-
M. Jucker and L. C. Walker, "Self-propagation of pathogenic protein aggregates in neurodegenerative diseases," Nature 501: 45-51 (2013).
-
(2013)
Nature
, vol.501
, pp. 45-51
-
-
Jucker, M.1
Walker, L.C.2
-
238
-
-
84888594143
-
Biology and ge ne tics of prions causing neurodegeneration
-
S. B. Prusiner, "Biology and ge ne tics of prions causing neurodegeneration," Annu. Rev. Genet. 47: 601-23 (2013).
-
(2013)
Annu. Rev. Genet
, vol.47
, pp. 601-623
-
-
Prusiner, S.B.1
|