Inhibition of aminoglycoside 6′-N-acetyltransferase type Ib by zinc: Reversal of amikacin resistance in Acinetobacter baumannii and Escherichia coli by a zinc ionophore

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 7, 2014, Pages 4238-4241

  Lin, David L ^a   Tran, Tung ^a   Alam, Jamal Y ^a   Herron, Steven R ^a,c   Ramirez, Maria Soledad ^a,b   Tolmasky, Marcelo E ^a  

^a CALIFORNIA STATE UNIVERSITY   (United States)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c Structure ase Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6' N ACETYLTRANSFERASE TYPE IB; AMIKACIN; AMINOGLYCOSIDE; PYRITHIONE ZINC; UNCLASSIFIED DRUG; ZINC CHLORIDE; ACYLTRANSFERASE; AMINOGLYCOSIDE N(6')-ACETYLTRANSFERASE; ANTIINFECTIVE AGENT; CHLORIDE; IONOPHORE; PYRIDINE DERIVATIVE; PYRITHIONE; THIOKETONE; ZINC DERIVATIVE;

ACINETOBACTER BAUMANNII; ARTICLE; BACTERIAL GROWTH; DRUG INHIBITION; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; ANTIBIOTIC RESISTANCE; DRUG EFFECTS; ENZYMOLOGY; MICROBIAL SENSITIVITY TEST;

ACETYLTRANSFERASES; ACINETOBACTER BAUMANNII; AMIKACIN; ANTI-BACTERIAL AGENTS; CHLORIDES; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; IONOPHORES; MICROBIAL SENSITIVITY TESTS; PYRIDINES; THIONES; ZINC COMPOUNDS;

EID: 84903218709     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00129-14     Document Type: Article

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