The role of substrate binding pocket residues phenylalanine 176 and phenylalanine 196 on Pseudomonas sp. OX1 toluene o-xylene monooxygenase activity and regiospecificity

Biotechnology and Bioengineering

Volumn 111, Issue 8, 2014, Pages 1506-1512

  Sönmez, Burcu ^a   Yanik Yildirim, K Cansu ^a   Wood, Thomas K ^b   Vardar Schara, Gönül ^a  

^a FATIH UNIVERSITY   (Turkey)

^b The Pennsylvania State University   (United States)

Author keywords

Regiospecific oxidation; Saturation mutagenesis; Toluene o xylene monooxygenase

Indexed keywords

AMINO ACIDS; HYDROXYLATION; MUTAGENESIS; NAPHTHALENE; NAPHTHOL; OXIDATION; SUBSTRATES; TOLUENE; XYLENE;

MONOOXYGENASE ACTIVITIES; NAPHTHALENE OXIDATION; OXIDATION ACTIVITIES; PRODUCT DISTRIBUTIONS; REGIOSPECIFIC OXIDATION; SATURATION MUTAGENESIS; TOLUENE-O-XYLENE MONOOXYGENASE; WILD-TYPE ENZYMES;

PHENOLS;

1 NAPHTHOL; 2 NAPHTHOL; BACTERIAL ENZYME; CATECHOL; HYDROQUINONE; META CRESOL; MUTANT PROTEIN; NAPHTHALENE; ORTHO CRESOL; PARA CRESOL; PHENOL; PHENYLALANINE; TOLUENE; TOLUENE 2 XYLENE MONOOXYGENASE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; NAPHTHOL DERIVATIVE; OXYGENASE; TOLUENE 2-XYLENE MONOOXYGENASE;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HYDROXYLATION; NUCLEOTIDE SEQUENCE; OXIDATION; PSEUDOMONAS; SITE DIRECTED MUTAGENESIS; STEREOSPECIFICITY; TOUA GENE; WILD TYPE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; STEREOISOMERISM;

AMINO ACID SUBSTITUTION; BINDING SITES; MODELS, MOLECULAR; NAPHTHOLS; OXIDATION-REDUCTION; OXYGENASES; PHENOL; PSEUDOMONAS; STEREOISOMERISM; TOLUENE;

EID: 84903193267     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25212     Document Type: Article

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