The dineolignan from Saururus chinensis, manassantin B, inhibits tumor-induced angiogenesis via downregulation of matrix metalloproteinases 9 in human endothelial cells

Oncology Reports

Volumn 32, Issue 2, 2014, Pages 659-667

  Liu, Zhaojie ^a   Lu, Hong ^a   Liu, Rong ^b   Chen, Bin ^a   Wang, Shan ^a   Ma, Junchao ^a   Fu, Jianjiang ^a  

^a JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b NANCHANG UNIVERSITY   (China)

Author keywords

Angiogenesis; Manassantin B; Matrix metalloproteinases 9; RUNX2; Saururus chinensis

Indexed keywords

GELATINASE B; MANASSANTIN B; NEOLIGNAN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; ANGIOGENESIS INHIBITOR; FURAN DERIVATIVE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTISEPTIC ACTIVITY; ARTICLE; CELL ADHESION; CELL INVASION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SAURURACEAE; SAURURUS CHINENSIS; TRADITIONAL MEDICINE; TUMOR GROWTH; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; METABOLISM; SPRAGUE DAWLEY RAT;

ANGIOGENESIS INHIBITORS; ANIMALS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FURANS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MATRIX METALLOPROTEINASE 9; RATS; RATS, SPRAGUE-DAWLEY; SAURURACEAE;

EID: 84903185804     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3244     Document Type: Article

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