Saucernetin-7 isolated from Saururus chinensis inhibits proliferation of human promyelocytic HL-60 leukemia cells via G0/G1 phase arrest and induction of differentiation

Carcinogenesis

Volumn 25, Issue 8, 2004, Pages 1387-1394

  Seo, Bo Rim ^d   Lee, Kyung Won ^d   Ha, Joohun ^a   Park, Hee Jun ^b   Choi, Jong Won ^c   Lee, Kyung Tae ^d  

^a Kyung Hee University Hospital   (South Korea)

^b Sangji University   (South Korea)

^c Kyungsung University   (South Korea)

^d Kyung Hee University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILEUKEMIC AGENT; CD14 ANTIGEN; CD66B ANTIGEN; CELL CYCLE PROTEIN; CYCLIN D1; CYCLIN D2; CYCLIN D3; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; DACTINOMYCIN; ESTERASE; LYMPHOCYTE ANTIGEN; MESSENGER RNA; NITROBLUE TETRAZOLIUM; PLANT EXTRACT; PROTEIN P21; PROTEIN P27; RETINOBLASTOMA PROTEIN; SAUCERNEIN 8; SAUCERNETIN 7; SAURURUS CHINENSIS EXTRACT; UNCLASSIFIED DRUG; CDK2 PROTEIN, HUMAN; CDK2 PROTEIN, MOUSE; CDK6 PROTEIN, HUMAN; CDK6 PROTEIN, MOUSE; CDKN1A PROTEIN, HUMAN; CDKN1A PROTEIN, MOUSE; CEACAM8 PROTEIN, HUMAN; CELL ADHESION MOLECULE; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; DNA; FURAN DERIVATIVE; GLUTATHIONE TRANSFERASE; LEUKOCYTE ANTIGEN; LIGNAN; SAUCERNETIN-7; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; TUMOR ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CANCER INHIBITION; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL STRAIN HL 60; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MEDICINAL PLANT; MORPHOGENESIS; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SAURURUS CHINENSIS; STEADY STATE; TRANSCRIPTION INITIATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL CYCLE; CELL DIVISION; CHEMICAL MODEL; GENETIC TRANSCRIPTION; METABOLISM; MOUSE; PHAGOCYTOSIS; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAURURACEAE; SERODIAGNOSIS; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD14; ANTIGENS, NEOPLASM; BLOTTING, WESTERN; CDC2-CDC28 KINASES; CELL ADHESION MOLECULES; CELL CYCLE; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLOW CYTOMETRY; FURANS; G0 PHASE; G1 PHASE; GLUTATHIONE TRANSFERASE; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LIGNANS; MICE; MODELS, CHEMICAL; PHAGOCYTOSIS; PHOSPHORYLATION; PLANT EXTRACTS; PRECIPITIN TESTS; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SAURURACEAE; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 4344649447     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh143     Document Type: Article

References (27)

1. Sawyers,C.L., Denny,C.T. and Witte,O.N. (1991) Leukemia and the disruption of normal hematopoiesis. Cell, 64, 337-350.
2. Steinman,R.A. (2002) Cell cycle regulators and hematopoiesis. Oncogene, 21, 3403-3413.
3. Furstenthal,L., Swanson,C., Kaiser,B.K., Eldridge,A.G. and Jackson,P.K. (2001) Triggering ubiquitination of a CDK inhibitor at origins of DNA replication. Nat. Cell Biol., 3, 715-722.
4. Sherr,C.J. (1996) Cancer cell cycles. Science, 274, 1672-1677.
5. Sherr,C.J. and Roberts,J.M. (1999) CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev., 13, 1501-1512.
6. Morgan,D.D. (1997) Cyclin dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell Dev. Biol., 13, 261-291.
7. Yu,J.T., Foster,R.G. and Dean,D.C. (2001) Transcriptional repression by RB-E2F and regulation of anchorage-independent survival. Mol. Cell. Biol., 21, 3325-3335.
8. Adams,P.D. (2001) Regulation of the retinoblastoma tumor suppressor protein by cyclin/CDKs. Biochim. Biophys. Acta, 1471, 123-133.
9. Lundberg,A.S. and Weinberg,R.A. (1998) Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol. Cell. Biol., 18, 753-761.
10. 3, retinoic acid and DMSO. Leuk. Res., 19, 57-64.
11. Drexler,H.G., Quentmeier,H., MacLeod,R.A., Uphoff,C.C. and Hu,Z.B. (1995) Leukemia cell lines: in vitro models for the study of acute promyelocytic leukemia. Leuk. Res., 19, 681-691.
12. Yam,L.T., Li,C.Y. and Crosby,W.H. (1971) Cytochemical identification of monocytes and granulocytes. Am. J. Clin. Pathol., 55, 283-290.
13. Chung,B.S. and Shin,M.G. (1990) Dictionary of Korean Folk Medicine. Young Lim Sa, Seoul.
14. 2 production from murine macrophage RAW 264.7 cells. Biol. Pharm. Bull., 26, 481-486.
15. Rao,K.V. and Puri,V.N. (1988) Hypothermic response produced by saururuslignan A, a novel neuroleptic agent. Life Sci., 42, 2717-2720.
16. Min,M., Jinlan,R. and Rao,K.V. (2001) Studies on chemical constituents of Saururus chinensis (I). Zhongcaoyao, 32, 9-11.
17. 3. J. Biol. Chem., 274, 16392-16399.
18. Hoffman,B. and Liebermann,D.A. (1994) Molecular controls of apoptosis: differentiation/growth arrest primary response genes, proto-oncogenes, and tumor suppressor genes as positive and negative modulators. Oncogene, 9, 1807-1812.
19. Jeong,S.H., Koo,S.J., Choi,J.H., Park,J.H., Ha,J., Park,H.J. and Lee,K.T. (2002) Intermedeol isolated from the leaves of Ligularia fischeri var. spiciformis induces the differentiation of human acute promyeocytic leukemia HL-60 Cells. Planta Med., 68, 881-885.
20. Steinman,R.A., Hoffman,B., Iro,A., Guillouf,C., Liebermann,D.A. and el-Houseini,M.E. (1994) Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene, 9, 3389-3396.
21. Macleod,K.F., Sherry,N., Hannon,G., Beach,D., Tokino,T., Kinzler,K., Vogelstein,B. and Jacks,T. (1995) p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev., 9, 935-944.
22. Dulic,V., Kaufmann,W.K., Wilson,S.J., Tlsty,T.D., Lees,E., Harper,J.W., Elledge,S.J. and Reed,S.I. (1994) p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell, 76, 1013-1023.
23. Noda,A., Ning,Y., Venable,S.F., Pereira-Smith,O.M. and Smith,J.R. (1994) Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res., 211, 90-98.
24. Jiang,H., Lin,J., Su,Z.Z., Collart,F.R., Huberman,E. and Fisher,P.B. (1994) Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, CIP/WAF1/CIP1, expression in the absence of p53. Oncogene, 9, 3397-3406.
25. WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway. Cancer Res., 56, 31-35.
26. KIP1 in PMA-induced differentiation of HL60 cells. FEBS Lett., 472, 50-52.
27. Barboule,N., Lafon,C., Chadebech,P., Vidal,S. and Valette,A. (1999) Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition. FEBS Lett., 444, 32-37.