Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 mice

Drug Metabolism and Disposition

Volumn 42, Issue 7, 2014, Pages 1146-1152

  Kutsuno, Yuki ^a   Itoh, Tomoo ^a   Tukey, Robert H ^b   Fujiwara, Ryoichi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b University of California San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; DICLOFENAC; ETODOLAC; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1; IBUPROFEN; INDOMETACIN; KETOPROFEN; NAPROXEN; UNCLASSIFIED DRUG; GLUCURONIDE; NONSTEROID ANTIINFLAMMATORY AGENT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG GLUCURONIDATION; DRUG LIVER LEVEL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; LIVER TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; SPECIES DIFFERENCE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; MICE; MICE, INBRED C57BL; SPECIES SPECIFICITY;

EID: 84903159694     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.114.057083     Document Type: Article

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