Cigarettes, genetic background, and menopausal timing: The presence of single nucleotide polymorphisms in cytochrome P450 genes is associated with increased risk of natural menopause in European-American smokers

Menopause

Volumn 21, Issue 7, 2014, Pages 694-701

  Butts, Samantha F ^a   Sammel, Mary D ^a   Greer, Christine ^b   Rebbeck, Timothy R ^a,c   Boorman, David W ^d   Freeman, Ellen W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Early menopause; Gene environment interaction; Menopause; Polyaromatic hydrocarbons; Smoking

Indexed keywords

ASPARAGINE; CYTOCHROME P450; ENVIRONMENTAL CHEMICAL; LEUCINE; METHIONINE; SERINE; STEROID HORMONE; VALINE;

ADULT; AFRICAN AMERICAN; ARTICLE; COMT GENE; CONTROLLED STUDY; CYP1B1 GENE; CYP3A4 GENE; EUROPEAN AMERICAN; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HORMONE METABOLISM; HUMAN; MAJOR CLINICAL STUDY; MENOPAUSE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SURVIVAL; WILD TYPE; CAUCASIAN; COHORT ANALYSIS; GENETICS; HOT FLASHES; MIDDLE AGED; RISK FACTOR; STATISTICS AND NUMERICAL DATA;

ADULT; COHORT STUDIES; CYTOCHROME P-450 ENZYME SYSTEM; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC VARIATION; HOT FLASHES; HUMANS; MENOPAUSE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SMOKING;

EID: 84903149914     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/GME.0000000000000140     Document Type: Article

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