-
1
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
-
Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007). (Pubitemid 350138099)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
2
-
-
79961131135
-
Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons
-
Qiang, L. et al. Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons. Cell 146, 359-371 (2011).
-
(2011)
Cell
, vol.146
, pp. 359-371
-
-
Qiang, L.1
-
3
-
-
80051674431
-
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
-
Caiazzo, M. et al. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 476, 224-227 (2011).
-
(2011)
Nature
, vol.476
, pp. 224-227
-
-
Caiazzo, M.1
-
4
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen, T. et al. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035-1041 (2010).
-
(2010)
Nature
, vol.463
, pp. 1035-1041
-
-
Vierbuchen, T.1
-
5
-
-
79959951387
-
Direct conversion of human fibroblasts to dopaminergic neurons
-
Pfisterer, U. et al. Direct conversion of human fibroblasts to dopaminergic neurons. Proc. Natl Acad. Sci. USA 108, 10343-10348 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 10343-10348
-
-
Pfisterer, U.1
-
6
-
-
79960854285
-
Induction of human neuronal cells by defined transcription factors
-
Pang, Z. P. et al. Induction of human neuronal cells by defined transcription factors. Nature 476, 220-223 (2011).
-
(2011)
Nature
, vol.476
, pp. 220-223
-
-
Pang, Z.P.1
-
7
-
-
80051684096
-
MicroRNA-mediated conversion of human fibroblasts to neurons
-
Yoo, A. S. et al. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 476, 228-231 (2011).
-
(2011)
Nature
, vol.476
, pp. 228-231
-
-
Yoo, A.S.1
-
8
-
-
79961173182
-
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions
-
Ambasudhan, R. et al. Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell 9, 113-118 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 113-118
-
-
Ambasudhan, R.1
-
9
-
-
80052295767
-
Conversion of mouse and human fibroblasts into functional spinal motor neurons
-
Son, E. Y. et al. Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell 9, 205-218 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 205-218
-
-
Son, E.Y.1
-
10
-
-
84863625049
-
Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor
-
Ring, K. L. et al. Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor. Cell Stem Cell 11, 100-109 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 100-109
-
-
Ring, K.L.1
-
11
-
-
80755129026
-
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts
-
Kim, J. et al. Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell 9, 413-419 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 413-419
-
-
Kim, J.1
-
12
-
-
84876667526
-
Generation of induced neurons via direct conversion in vivo
-
Torper, O. et al. Generation of induced neurons via direct conversion in vivo. Proc. Natl Acad. Sci. USA 110, 7038-7043 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 7038-7043
-
-
Torper, O.1
-
13
-
-
84872601985
-
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated micro RNA circuits
-
Xue, Y. et al. Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell 152, 82-96 (2013).
-
(2013)
Cell
, vol.152
, pp. 82-96
-
-
Xue, Y.1
-
14
-
-
84897141348
-
Direct conversion of mouse fibroblasts into induced neural stem cells
-
Kim, S. M. et al. Direct conversion of mouse fibroblasts into induced neural stem cells. Nat. Protoc. 9, 871-881 (2014).
-
(2014)
Nat. Protoc.
, vol.9
, pp. 871-881
-
-
Kim, S.M.1
-
15
-
-
69349098273
-
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
-
Utikal, J. et al. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature 460, 1145-1148 (2009).
-
(2009)
Nature
, vol.460
, pp. 1145-1148
-
-
Utikal, J.1
-
16
-
-
69349103956
-
The Ink4/Arf locus is a barrier for iPS cell reprogramming
-
Li, H. et al. The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 460, 1136-1139 (2009).
-
(2009)
Nature
, vol.460
, pp. 1136-1139
-
-
Li, H.1
-
17
-
-
34447543913
-
Cellular senescence in cancer and aging
-
DOI 10.1016/j.cell.2007.07.003, PII S0092867407008902
-
Collado, M., Blasco, M. A. & Serrano, M. Cellular senescence in cancer and aging. Cell 130, 223-233 (2007). (Pubitemid 47081143)
-
(2007)
Cell
, vol.130
, Issue.2
, pp. 223-233
-
-
Collado, M.1
Blasco, M.A.2
Serrano, M.3
-
18
-
-
59649109187
-
Cellular senescence, telomere recombination and maintenance
-
Yang, Q. Cellular senescence, telomere recombination and maintenance. Cytogenet. Genome Res. 122, 211-218 (2008).
-
(2008)
Cytogenet. Genome Res.
, vol.122
, pp. 211-218
-
-
Yang, Q.1
-
19
-
-
37549003175
-
Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence
-
Yang, Q. et al. Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence. Cancer Res. 67, 11677-11686 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 11677-11686
-
-
Yang, Q.1
-
20
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
DOI 10.1093/emboj/cdg417
-
Beausejour, C. M. et al. Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J 22, 4212-4222 (2003). (Pubitemid 37021749)
-
(2003)
EMBO Journal
, vol.22
, Issue.16
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
Narita, M.4
Lowe, S.W.5
Yaswen, P.6
Campisi, J.7
-
21
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
DOI 10.1016/j.cell.2005.02.003
-
Campisi, J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120, 513-522 (2005). (Pubitemid 40269765)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 513-522
-
-
Campisi, J.1
-
22
-
-
84859555919
-
Direct conversion of fibroblasts into stably expandable neural stem cells
-
Thier, M. et al. Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell 10, 473-479 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 473-479
-
-
Thier, M.1
-
23
-
-
77951878056
-
Induced pluripotent stem cells and senescence: Learning the biology to improve the technology
-
Banito, A. & Gil, J. Induced pluripotent stem cells and senescence: learning the biology to improve the technology. EMBO Rep. 11, 353-359 (2010).
-
(2010)
EMBO Rep.
, vol.11
, pp. 353-359
-
-
Banito, A.1
Gil, J.2
-
24
-
-
70349093119
-
Senescence impairs successful reprogramming to pluripotent stem cells
-
Banito, A. et al. Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev. 23, 2134-2139 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 2134-2139
-
-
Banito, A.1
-
25
-
-
79952538234
-
Reprogramming to pluripotency: Stepwise resetting of the epigenetic landscape
-
Papp, B. & Plath, K. Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. Cell Res. 21, 486-501 (2011).
-
(2011)
Cell Res.
, vol.21
, pp. 486-501
-
-
Papp, B.1
Plath, K.2
-
26
-
-
79251518046
-
Mechanistic insights into reprogramming to induced pluripotency
-
Ho, R., Chronis, C. & Plath, K. Mechanistic insights into reprogramming to induced pluripotency. J. Cell Physiol. 226, 868-878 (2011).
-
(2011)
J. Cell Physiol.
, vol.226
, pp. 868-878
-
-
Ho, R.1
Chronis, C.2
Plath, K.3
-
27
-
-
79956212343
-
Constructing and deconstructing stem cell models of neurological disease
-
Han, S. S., Williams, L. A. & Eggan, K. C. Constructing and deconstructing stem cell models of neurological disease. Neuron 70, 626-644 (2011).
-
(2011)
Neuron
, vol.70
, pp. 626-644
-
-
Han, S.S.1
Williams, L.A.2
Eggan, K.C.3
-
28
-
-
84858390754
-
Reprogramming cellular identity for regenerative medicine
-
Cherry, A. B. & Daley, G. Q. Reprogramming cellular identity for regenerative medicine. Cell 148, 1110-1122 (2012).
-
(2012)
Cell
, vol.148
, pp. 1110-1122
-
-
Cherry, A.B.1
Daley, G.Q.2
-
29
-
-
84856007232
-
The promise of induced pluripotent stem cells in research and therapy
-
Robinton, D. A. & Daley, G. Q. The promise of induced pluripotent stem cells in research and therapy. Nature 481, 295-305 (2012).
-
(2012)
Nature
, vol.481
, pp. 295-305
-
-
Robinton, D.A.1
Daley, G.Q.2
-
30
-
-
84866780162
-
Molecular roadblocks for cellular reprogramming
-
Vierbuchen, T. & Wernig, M. Molecular roadblocks for cellular reprogramming. Mol. Cell 47, 827-838 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 827-838
-
-
Vierbuchen, T.1
Wernig, M.2
-
31
-
-
82755164294
-
Induced neuronal cells: How to make and define a neuron
-
Yang, N., Ng, Y. H., Pang, Z. P., Sudhof, T. C. & Wernig, M. Induced neuronal cells: how to make and define a neuron. Cell Stem Cell 9, 517-525 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 517-525
-
-
Yang, N.1
Ng, Y.H.2
Pang, Z.P.3
Sudhof, T.C.4
Wernig, M.5
-
32
-
-
84861990748
-
Small molecules enable highly efficient neuronal conversion of human fibroblasts
-
Ladewig, J. et al. Small molecules enable highly efficient neuronal conversion of human fibroblasts. Nat. Methods 9, 575-578 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 575-578
-
-
Ladewig, J.1
-
33
-
-
84880849098
-
Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons
-
Liu, M. L. et al. Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons. Nat. Commun. 4, 2183-3183 (2013).
-
(2013)
Nat. Commun.
, vol.4
, pp. 2183-3183
-
-
Liu, M.L.1
-
34
-
-
84879255268
-
Remodeling neurodegeneration: Somatic cell reprogramming-based models of adult neurological disorders
-
Qiang, L., Fujita, R. & Abeliovich, A. Remodeling neurodegeneration: somatic cell reprogramming-based models of adult neurological disorders. Neuron 19, 957-969 (2013).
-
(2013)
Neuron
, vol.19
, pp. 957-969
-
-
Qiang, L.1
Fujita, R.2
Abeliovich, A.3
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