Tumor archaeology: Tracking leukemic evolution to its origins

Science Translational Medicine

Volumn 6, Issue 238, 2014, Pages

  Dick, John E ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; VEMURAFENIB;

B LYMPHOCYTE; CELL RENEWAL; DRUG TARGETING; GENE MUTATION; HAIRY CELL LEUKEMIA; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL; HUMAN; LEUKEMOGENESIS; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; BIOLOGICAL MODEL; GENETICS; LEUKEMIA; MOLECULAR EVOLUTION; MUTATION; PATHOLOGY;

EVOLUTION, MOLECULAR; HUMANS; LEUKEMIA; MODELS, BIOLOGICAL; MUTATION;

EID: 84902793783     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3009168     Document Type: Short Survey

References (10)

1. M. S. Lawrence, P. Stojanov, C. H. Mermel, J. T. Robinson, L. A. Garraway, T. R. Golub, M. Meyerson, S. B. Gabriel, E. S. Lander, G. Getz, Discovery and saturation analysis of cancer genes across 21 tumour types. Nature 505, 495-501 (2014).
2. M. Greaves, C. C. Maley, Clonal evolution in cancer. Nature 481, 306-313 (2012).
3. S. S. Chung, E. Kim, J. H. Park, Y. R. Chung, P. Lito, J. Teruya-Feldstein, W. Hu, W. Beguelin, S. Monette, C. Duy, R. Rampal, L. Telis, M. Patel, M. K. Kim, K. Huberman, N. Bouvier, M. F. Berger, A. M. Melnick, N. Rosen, M. S. Tallman, C. Y. Park, O. Abdel-Wahab, Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia. Sci. Transl. Med. 6, 238ra71 (2014).
4. A. Pandolfi, L. Barreyro, U. Steidl, Concise review: Preleukemic stem cells: Molecular biology and clinical implications of the precursors to leukemia stem cells. Stem Cells Transl. Med. 2, 143-150 (2013).
5. S. Doulatov, F. Notta, E. Laurenti, J. E. Dick, Hematopoiesis: A human perspective. Cell Stem Cell 10, 120-136 (2012).
6. L. I. Shlush, S. Zandi, A. Mitchell, W. C. Chen, J. M. Brandwein, V. Gupta, J. A. Kennedy, A. D. Schimmer, A. C. Schuh, K. W. Yee, J. L. McLeod, M. Doedens, J. J. Medeiros, R. Marke, H. J. Kim, K. Lee, J. D. McPherson, T. J. Hudson, A. M. Brown, F. Yousif, Q. M. Trinh, L. D. Stein, M. D. Minden, J. C. Wang, J. E. Dick, HALT Pan-Leukemia Gene Panel Consortium, Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature 506, 328-333 (2014).
7. M. R. Corces-Zimmerman, W. J. Hong, I. L. Weissman, B. C. Medeiros, R. Majeti, Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc. Natl. Acad. Sci. U.S.A. 111, 2548-2553 (2014).
8. C. Leung-Hagesteijn, N. Erdmann, G. Cheung, J. J. Keats, A. K. Stewart, D. E. Reece, K. C. Chung, R. E. Tiedemann, Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma. Cancer Cell 24, 289-304 (2013).
9. J. Zhang, L. Ding, L. Holmfeldt, G. Wu, S. L. Heatley, D. Payne-Turner, J. Easton, X. Chen, J. Wang, M. Rusch, C. Lu, S. C. Chen, L. Wei, J. R. Collins-Underwood, J. Ma, K. G. Roberts, S. B. Pounds, A. Ulyanov, J. Becksfort, P. Gupta, R. Huether, R. W. Kriwacki, M. Parker, D. J. McGoldrick, D. Zhao, D. Alford, S. Espy, K. C. Bobba, G. Song, D. Pei, C. Cheng, S. Roberts, M. I. Barbato, D. Campana, E. Coustan-Smith, S. A. Shurtleff, S. C. Raimondi, M. Kleppe, J. Cools, K. A. Shimano, M. L. Hermiston, S. Doulatov, K. Eppert, E. Laurenti, F. Notta, J. E. Dick, G. Basso, S. P. Hunger, M. L. Loh, M. Devidas, B. Wood, S. Winter, K. P. Dunsmore, R. S. Fulton, L. L. Fulton, X. Hong, C. C. Harris, D. J. Dooling, K. Ochoa, K. J. Johnson, J. C. Obenauer, W. E. Evans, C. H. Pui, C. W. Naeve, T. J. Ley, E. R. Mardis, R. K. Wilson, J. R. Downing, C. G. Mullighan, The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 481, 157-163 (2012).
10. Y. Kikushige, F. Ishikawa, T. Miyamoto, T. Shima, S. Urata, G. Yoshimoto, Y. Mori, T. Iino, T. Yamauchi, T. Eto, H. Niiro, H. Iwasaki, K. Takenaka, K. Akashi, Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia. Cancer Cell 20, 246-259 (2011).