Generation of mastitis resistance in cows by targeting human lysozyme gene to β-casein locus using zinc-finger nucleases

Proceedings of the Royal Society B: Biological Sciences

Volumn 281, Issue 1780, 2014, Pages

  Liu, Xu ^a   Wang, Yongsheng ^a   Tian, Yuchen ^a   Yu, Yuan ^a   Gao, Mingqing ^a   Hu, Guangdong ^a   Su, Feng ^a   Pan, Shaohui ^a   Luo, Yan ^a   Guo, Zekun ^a   Quan, Fusheng ^a   Zhang, Yong ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Gene targeting; Mastitis; Nuclear transfer; Zinc finger nucleases; casein locus

Indexed keywords

CASEIN; LYSOZYME; ZINC FINGER PROTEIN;

ANIMAL WELFARE; ANTIMICROBIAL ACTIVITY; CATTLE; DISEASE CONTROL; DISEASE RESISTANCE; ENZYME ACTIVITY; GENE EXPRESSION; GENE TRANSFER; GENETIC ENGINEERING; GENETICALLY MODIFIED ORGANISM; MILK; PEPTIDE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BOVINE MASTITIS; CATTLE; CELL NUCLEUS TRANSPLANTATION; CLONING; DISEASE RESISTANCE; ENZYMOLOGY; FEMALE; FIBROBLAST; GENE TARGETING; GENETICS; GENOMICS; HUMAN; MASTITIS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PREVENTION; REPORTER GENE; SEQUENCE ALIGNMENT; TRANSGENIC ORGANISM; ZINC-FINGER NUCLEASES; Β-CASEIN LOCUS;

GENE TARGETING; MASTITIS; NUCLEAR TRANSFER; ZINC-FINGER NUCLEASES; Β-CASEIN LOCUS;

ANIMALS; BASE SEQUENCE; CASEINS; CATTLE; CLONING, ORGANISM; DISEASE RESISTANCE; ENZYMOLOGY; FEMALE; FIBROBLASTS; GENE TARGETING; GENES, REPORTER; GENETICS; GENOMICS; HUMANS; MASTITIS, BOVINE; MOLECULAR SEQUENCE DATA; MURAMIDASE; NUCLEAR TRANSFER TECHNIQUES; ORGANISMS, GENETICALLY MODIFIED; PREVENTION AND CONTROL; SEQUENCE ALIGNMENT; VETERINARY; ZINC FINGERS;

EID: 84902682953     PISSN: 09628452     EISSN: 14712954     Source Type: Journal    
DOI: 10.1098/rspb.2013.3368     Document Type: Article

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