Kaposi's sarcoma-associated herpesvirus ORF6 gene is essential in viral lytic replication

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Peng, Can ^a   Chen, Jungang ^a   Tang, Wei ^a   Liu, Chunlan ^a   Chen, Xulin ^a  

^a WUHAN INSTITUTE OF VIROLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; HYGROMYCIN; KANAMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; VIRUS DNA; VIRUS PROTEIN;

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CARCINOGENESIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA REPLICATION; DNA SYNTHESIS; EMBRYO; GENE CONSTRUCT; GENE DELETION; GENE EXPRESSION; GENE LOCUS; HERPES VIRUS; HUMAN; HUMAN CELL; KAPOSI SARCOMA; LIFE CYCLE STAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORF6 GENE; SUPERNATANT; VIRUS EXPRESSION; VIRUS GENE; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS LYTIC LIFE CYCLE STAGE; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS STRAIN; CELL LINE; GENETIC COMPLEMENTATION; GENETICS; HERPES VIRUS INFECTION; HUMAN HERPESVIRUS 8; MUTATION; OPEN READING FRAME; PHYSIOLOGY; VIROLOGY;

CELL LINE; GENE DELETION; GENE EXPRESSION; GENETIC COMPLEMENTATION TEST; GENOME, VIRAL; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HUMANS; MUTATION; OPEN READING FRAMES; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84902680006     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099542     Document Type: Article

References (48)

1. Russo JJ, Bohenzky RA, Chien MC, Chen J, Yan M, et al. (1996) Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc Natl Acad Sci U S A 93: 14862-14867. (Pubitemid 26419060)
2. Dourmishev LA, Dourmishev AL, Palmeri D, Schwartz RA, Lukac DM (2003) Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpes-virus-8) epidemiology and pathogenesis. Microbiol Mol Biol Rev 67: 175-212, table of contents. (Pubitemid 36693471)
3. Ganem D (2006) KSHV infection and the pathogenesis of Kaposi's sarcoma. Annu Rev Pathol 1: 273-296.
4. Renne R, Zhong W, Herndier B, McGrath M, Abbey N, et al. (1996) Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat Med 2: 342-346. (Pubitemid 26080656)
5. Parravicini C, Chandran B, Corbellino M, Berti E, Paulli M, et al. (2000) Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Am J Pathol 156: 743-749. (Pubitemid 30626930)
6. Miller G, Heston L, Grogan E, Gradoville L, Rigsby M, et al. (1997) Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells. Journal of Virology 71: 314-324. (Pubitemid 26412294)
7. Wang Y, Li H, Chan MY, Zhu FX, Lukac DM, et al. (2004) Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: cis-Acting Requirements for Replication and ori-Lyt-Associated RNA Transcription. Journal of Virology 78: 8615-8629. (Pubitemid 39025128)
8. Chen L, Lagunoff M (2005) Establishment and Maintenance of Kaposi's Sarcoma-Associated Herpesvirus Latency in B Cells. Journal of Virology 79: 14383-14391. (Pubitemid 41552735)
9. Zhong W, Wang H, Herndier B, Ganem D (1996) Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma. Proceedings of the National Academy of Sciences 93: 6641-6646. (Pubitemid 26230362)
10. AuCoin DP, Colletti KS, Cei SA, Papouskova I, Tarrant M, et al. (2004) Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (KRta) and K8 (K-bZIP). Virology 318: 542-555. (Pubitemid 38224298)
11. Wu FY, Ahn J-H, Alcendor DJ, Jang W-J, Xiao J, et al. (2001) Origin-Independent Assembly of Kaposi's Sarcoma-Associated Herpesvirus DNA Replication Compartments in Transient Cotransfection Assays and Association with the ORF-K8 Protein and Cellular PML. Journal of Virology 75: 1487-1506. (Pubitemid 32094706)
12. Lukac DM, Renne R, Kirshner JR, Ganem D (1998) Reactivation of Kaposi's Sarcoma-Associated Herpesvirus Infection from Latency by Expression of the ORF 50 Transactivator, a Homolog of the EBV R Protein. Virology 252: 304-312. (Pubitemid 29013411)
13. Lukac DM, Kirshner JR, Ganem D (1999) Transcriptional Activation by the Product of Open Reading Frame 50 of Kaposi's Sarcoma-Associated Herpesvirus Is Required for Lytic Viral Reactivation in B Cells. Journal of Virology 73: 9348-9361. (Pubitemid 29487090)
14. Liang Y, Chang J, Lynch SJ, Lukac DM, Ganem D (2002) The lytic switch protein of KSHV activates gene expression via functional interaction with RBPJk (CSL), the target of the Notch signaling pathway. Genes & Development 16: 1977-1989. (Pubitemid 34832925)
15. Nicholas J, Ruvolo V, Zong J, Ciufo D, Guo HG, et al. (1997) A single 13-kilobase divergent locus in the Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genome contains nine open reading frames that are homologous to or related to cellular proteins. Journal of Virology 71: 1963-1974. (Pubitemid 27078575)
16. Godowski PJ, Knipe DM (1986) Transcriptional control of herpesvirus gene expression: Gene function required for positive and negative regulation. Proceedings of the National Academy of Sciences of the United States of America 83: 256-260. (Pubitemid 16079992)
17. Gao M, Knipe DM (1991) Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expression. Journal of Virology 65: 2666-2675.
18. Bush M, Yager DR, Gao M, Weisshart K, Marcy AI, et al. (1991) Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein. Journal of Virology 65: 1082-1089.
19. McNamee EE, Taylor TJ, Knipe DM (2000) A dominant-negative herpesvirus protein inhibits intranuclear targeting of viral proteins: Effects on DNA replication and late gene expression. Journal of Virology 74: 10122-10131.
20. Hernandez TR, Lehman IR (1990) Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein. Journal of Biological Chemistry 265: 11227-11232.
21. He X, Lehman IR (2001) An initial ATP-independent step in the unwinding of a herpes simplex virus type I origin of replication by a complex of the viral originbinding protein and single-strand DNA-binding protein. Proc Natl Acad Sci U S A 98: 3024-3028. (Pubitemid 32220793)
22. Falkenberg M, Elias P, Lehman IR (1998) The Herpes Simplex Virus Type 1 Helicase-primase: ANALYSIS OF HELICASE ACTIVITY. Journal of Biological Chemistry 273: 32154-32157. (Pubitemid 29177160)
23. Taylor TJ, Knipe DM (2004) Proteomics of herpes simplex virus replication compartments: Association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8. Journal of Virology 78: 5856-5866. (Pubitemid 38661673)
24. Decaussin G, Leclerc V, Ooka T (1995) The Lytic Cycle of Epstein-Barr-Virus in the Nonproducer Raji Line Can Be Rescued by the Expression of a 135-Kilodalton Protein Encoded by the Balf2 Open Reading Frame. Journal of Virology 69: 7309-7314.
25. Tibbetts SA, Suarez F, Steed AL, Simmons JA, Virgin Iv HW (2006) A [gamma]-herpesvirus deficient in replication establishes chronic infection in vivo and is impervious to restriction by adaptive immune cells. Virology 353: 210-219. (Pubitemid 44308490)
26. Song MJ, Hwang SM, Wong WH, Wu TT, Lee SM, et al. (2005) Identification of viral genes essential for replication of murine gamma-herpesvirus 68 using signature-tagged mutagenesis. Proceedings of the National Academy of Sciences of the United States of America 102: 3805-3810. (Pubitemid 40354693)
27. Dunn W, Chou C, Li H, Hai R, Patterson D, et al. (2003) Functional profiling of a human cytomegalovirus genome. Proc Natl Acad Sci U S A 100: 14223-14228. (Pubitemid 37499218)
28. Zhou FC, Zhang YJ, Deng JH, Wang XP, Pan HY, et al. (2002) Efficient infection by a recombinant Kaposi's sarcoma-associated herpesvirus cloned in a bacterial artificial chromosome: Application for genetic analysis. Journal of Virology 76: 6185-6196.
29. Wang Y, Sathish N, Hollow C, Yuan Y (2011) Functional Characterization of Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame K8 by Bacterial Artificial Chromosome-Based Mutagenesis. Journal of Virology 85: 1943-1957.
30. Ye FC, Zhou FC, Yoo SM, Xie JP, Browning PJ, et al. (2004) Disruption of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistence. Journal of Virology 78: 11121-11129. (Pubitemid 39299652)
31. Lee EC, Yu D, Martinez de Velasco J, Tessarollo L, Swing DA, et al. (2001) A Highly Efficient Escherichia coli-Based Chromosome Engineering System Adapted for Recombinogenic Targeting and Subcloning of BAC DNA. Genomics 73: 56-65. (Pubitemid 32382387)
32. Krishnan HH, Naranatt PP, Smith MS, Zeng L, Bloomer C, et al. (2004) Concurrent Expression of Latent and a Limited Number of Lytic Genes with Immune Modulation and Antiapoptotic Function by Kaposi's Sarcoma-Associated Herpesvirus Early during Infection of Primary Endothelial and Fibroblast Cells and Subsequent Decline of Lytic Gene Expression. Journal of Virology 78: 3601-3620. (Pubitemid 38568301)
33. Bechtel JT, Liang Y, Hvidding J, Ganem D (2003) Host Range of Kaposi's Sarcoma-Associated Herpesvirus in Cultured Cells. Journal of Virology 77: 6474-6481. (Pubitemid 36588417)
34. Zhu FX, Chong JM,Wu L, Yuan Y (2005) Virion Proteins of Kaposi's Sarcoma-Associated Herpesvirus. Journal of Virology 79: 800-811. (Pubitemid 40053863)
35. Gao M, Knipe DM (1989) Genectic Evidence for Multiple Nuclear Functions of the Herpes Simplex Virus ICP8 DNA-Binding Protein. Journal of Virology 63: 5258-5267. (Pubitemid 19278765)
36. Kinchington PR, Inchauspe G, Subak-Sharpe JH, Robey F, Hay J, et al. (1988) Identification and characterization of a varicella-zoster virus DNA-binding protein by using antisera directed against a predicted synthetic oligopeptide. Journal of Virology 62: 802-809. (Pubitemid 18068636)
37. Lu M, Suen J, Frias C, Pfeiffer R, Tsai M-H, et al. (2004) Dissection of the Kaposi's Sarcoma-Associated Herpesvirus Gene Expression Program by Using the Viral DNA Replication Inhibitor Cidofovir. Journal of Virology 78: 13637-13652. (Pubitemid 39612763)
38. Sathish N, Yuan Y (2010) Functional characterization of Kaposi's sarcoma-associated herpesvirus small capsid protein by bacterial artificial chromosome-based mutagenesis. Virology In Press, Corrected Proof.
39. Majerciak V, Pripuzova N, McCoy JP, Gao SJ, Zheng ZM (2007) Targeted disruption of Kaposi's sarcoma-associated herpesvirus ORF57 in the viral genome is detrimental for the expression of ORF59, K8 alpha, and K8.1 and the production of infectious virus. Journal of Virology 81: 1062-1071. (Pubitemid 46167830)
40. Xu YY, Rodriguez-Huete A, Pari GS (2006) Evaluation of the lytic origins of replication of Kaposi's sarcoma-associated virus/human herpesvirus 8 in the context of the viral genome. Journal of Virology 80: 9905-9909. (Pubitemid 44435666)
41. Yakushko Y, Hackmann C, Günther T, Rückert J, Henke M, et al. (2011) Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Contains a Duplication of a Long Unique-Region Fragment within the Terminal Repeat Region. Journal of Virology 85: 4612-4617.
42. Brulois KF, Chang H, Lee AS-Y, Ensser A, Wong L-Y, et al. (2012) Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus Bacterial artificial chromosome clone. Journal of Virology.
43. Budt M, Hristozova T, Hille G, Berger K, Brune W (2011) Construction of a Lytically Replicating Kaposi's Sarcoma-Associated Herpesvirus. Journal of Virology 85: 10415-10420.
44. Godowski PJ, Knipe DM (1986) Transcriptional control of herpesvirus gene expression: gene functions required for positive and negative regulation. Proc Natl Acad Sci U S A 83: 256-260. (Pubitemid 16079992)
45. Cohen JI, Krogmann T, Pesnicak L, Ali MA (2007) Absence or Overexpression of the Varicella-Zoster Virus (VZV) ORF29 Latency-Associated Protein Impairs Late Gene Expression and Reduces VZV Latency in a Rodent Model. Journal of Virology 81: 1586-1591. (Pubitemid 46214433)
46. He H, Boucaud D, Hay J, Ruyechan WT (2001) Cis and trans elements regulating expression of the varicella zoster virus gI gene. Arch Virol Suppl: 57-70. (Pubitemid 33760018)
47. Wang Y, Li H, Tang Q, Maul GG, Yuan Y (2008) Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: Involvement of Host Cellular Factors. Journal of Virology 82: 2867-2882. (Pubitemid 351329177)
48. Uetz P, Dong Y-A, Zeretzke C, Atzler C, Baiker A, et al. (2006) Herpesviral Protein Networks and Their Interaction with the Human Proteome. Science 311: 239-242. (Pubitemid 43108191)