Ellagitannin geraniin supplementation ameliorates metabolic risks in high-fat diet-induced obese Sprague Dawley rats

Journal of Functional Foods

Volumn 9, Issue 1, 2014, Pages 173-182

  Chung, Alexis Panny Y S ^a   Ton, So Ha ^a   Gurtu, Sunil ^a   Palanisamy, Uma D ^a  

^a MONASH UNIVERSITY MALAYSIA   (Malaysia)

Author keywords

Beta cell dysfunction; Geraniin; High fat diet; Insulin sensitivity; Metabolic dysfunction; Nephelium lappaceum

Indexed keywords

EID: 84902661621     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2014.03.029     Document Type: Article

References (46)

1. Agabegi D.E., Steven S. Consumer reports health best buy drugs. The oral diabetes drugs: Treating type 2 diabetes. Best Buy Drugs (Consumer Reports), 20. Step-Up to Medicine (Step-Up Series) 2008, 185. Wolters Kluwer Health: Lippincott Williams & Wilkins, Philadelphia. D.E. Agabegi, M.D. Hagerstwon (Eds.).
2. Aggarwal N., Shishu A. A review of recent investigations on medicinal herbs processing anti-diabetic properties. Journal of Nutritional Disorders & Therapy 2011, 1(102):1-10.
3. Agrawal V., Shah A., Rice C., Franklin B.A., McCullough P.A. Impact of treating the metabolic syndrome on chronic kidney disease. Nature Reviews Nephrology 2009, 5:520-528.
4. Ambrose S.S., Solairaj P., Subramoniam A. Hepatoprotective activity of geraniin isolated from Thespesia lampas Dalz. and Gibson. International Research Journal of Pharmacy and Pharmacology 2012, 2(4):92-96.
5. American Diabetes Association Consensus development of the American Diabetes Association. Diabetes Care 2001, 24(1):S69-S72.
6. Andrikopoulos S., Massa M.C., Aston-Mourney K., Funkat A., Fam C.B., Hull L.R., Kahn E.S., Proietto J. Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high-fat diet. Journal of Endocrinology 2005, 187:45-53.
7. Baur J.A., Pearson K.J., Price N.L., Jamieson H.A., Lerin C., Kalra A., Prabhu V.V., Allard J.S., Lopez-Lluch G., Lewis K., Pistell P.J., Poosala S., Becker K.G., Boss O., Gwinn D., Wang M., Ramaswamy S., Fishbein K.W., Spencer R.G., Lakatta E.G., Le Couteur D., Shaw R.J., Navas P., Puigserver P., Ingram D.K., de Cabo R., Sinclair D.A. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006, 444:1-6.
8. Bonora E., Targher G., Alberiche M., Bonadonna R.C., Saggiani F., Zenere M.B., Monauni T., Muggeo M. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity. Diabetes Care 2000, 23:57-63.
9. Buettner R., Parhofer K.G., Woenckhaus M., Wrede C.E., Kunz-Schughart L.A., Scholmerich J., Bollheimer L.C. Defining high-fat-diet rat models: Metabolic and molecular effects of different fat types. Journal of Molecular Endocrinology 2006, 36:485-501.
10. Buettner R., Scholmerich J., Bollheimer L.C. High-fat diets: Modelling the metabolic disorders of human obesity in rodents. Obesity 2007, 15(4):798-808.
11. Campbell M.J., Machin D. Medical Statistics: A Common Sense Approach 1999, John Wiley, New York. 3rd edn.
12. Chang C.J., Tzeng T.F., Liou S.S., Chang Y.S., Liu I.M. Kaempferol regulates the lipid-profile in high-fat diet-fed rats through an increase in hepatic PPARα levels. Planta Medica 2011, 77:1876-1882.
13. Chen Y.K., Cheung C., Reuhl K.R., Liu A.B., Lee M.J., Lu Y.P., Chung S.Y. Effects of green tea polyphenol (-) epigallocatechin-3-gallate on newly developed high-fat/western-style diet-induced obesity and metabolic syndrome in mice. Journal of Agricultural and Food Chemistry 2011, 10.1021/jf2029016.
14. Christopher D.B., Sarah H.W. The Metabolic Syndrome 2005, John Wiley & Sons Ltd, England.
15. Doshi J.C., Vaidya A.B., Antarkar D.S., Deolalikar R., Antani D.H. A two-stage clinical trial of Phyllanthus amarus in hepatitis B carriers: Failure to eradicate the surface antigen. Indian Journal of Gastroenterology 1994, 13(1):7-8.
16. Gajda A.M., Pellizzon M.A., Ricci M.R., Ulman E.A. Diet-induced metabolic syndrome in rodent models. Animal Lab News 2007, 1-8.
17. Giannini E.G., Testa R., Savarino V. Liver enzyme alteration: A guide for clinicians. Canadian Medical Association Journal 2005, 172(3):367-379.
18. Guilherme A., Virbasius J.V., Puri V., Czech M.P. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nature Reviews. Molecular Cell Biology 2008, 9:9367-9377.
19. Hegsted D.M., Ausman L.M., Johnson J.A., Dallal G.E. Dietary fat and serum lipids: An evaluation of the experimental data. American Journal of Nutrition 1993, 57:875-883.
20. Hwang L.L., Wang C.H., Li T.L., Chang S.D., Lin L.C., Chen C.P., Chen C.T., Liang K.C., Ho I.K., Yang W.S., Chiou L.C. Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice. Obesity 2010, 18(3):463-469.
21. Ikarashi N., Toda T., Okaniwa T., Ito K., Ochiai W., Sugiyama K. Anti-obesity and anti-diabetic effects of Acacia polyphenol in obese diabetic KKAy mice fed high-fat diet. Evidence-based Complementary and Alternative Medicine 2011, 1-10.
22. Ito H. Metabolites of the ellagitannin geraniin and their antioxidant activities. Planta Medica 2011, 77:1110-1115.
23. Khanal R.C., Howard L.R., Wikes S.E., Rogers T.J., Prior R.L. Cranberry pomace partially ameliorates metabolic factors associated with high fructose feeding in growing Sprague-Dawley rats. Journal of Functional Foods 2010, 2:284-291.
24. Krishnaveni M., Mirunalini S. Therapeutic potential of Phyllanthus emblica (amla): The ayurvedic wonder. Journal of Basic and Clinical Physiology and Pharmacology 2010, 21(1):93-105.
25. Kumaran A., Karunakaran R.J. Nitride oxide radical scavenging active components from Phyllanthus emblica L. Plant Foods for Human Nutrition 2006, 61:1-5.
26. Li H.K., Xie Z.Q., Lin J.C., Song H.G., Wang Q., Wang K., Su M., Qiu Y., Zhao T., Song K., Wang X., Zhou M., Liu P., Zhao G., Zhang Q., Jia W. Transcriptomic and metabonomic profiling of obesity-prone and obesity-resistant rats under high-fat diet. Journal of Proteome Research 2008, 7:4775-4783.
27. Lin S.Y., Wang C.C., Lu Y.L., Wu W.C., Hou W.C. Antioxidant, anti-semicarbazide-sensitive amine oxidase and anti-hypertensive activities of geraniin isolated from Phyllanthus urinaria. Food and Chemical Toxicology 2008, 46(7):2485-2492.
28. McGarry J.D. Banting Lecture 2001. Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002, 51:8-18.
29. Moller D.E. New drug targets for type 2 diabetes and the metabolic syndrome. Nature 2001, 414:821-827.
30. National Heart, Lung and Blood Institute National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults: Executive summary of the third report. Journal of the American Medical Association 2001, 285:2486-2496.
31. Nelson J.E., Wilson L., Brunt E.M., Yeh M.M., Kleiner D.E., Unalp-Arida A., Kowdley K.V. The non-alcoholic steatohepatitis clinical research network relationship between the pattern of hepatic iron deposition and histological severity in non-alcoholic fatty liver disease. Hepatology (Baltimore, Md.) 2011, 53:448-457.
32. Ostenson C.G. The pathophysiology of type 2 diabetes mellitus: An overview. Acta Physiological Scandinavica 2001, 171:241-247.
33. Palanisamy U., Cheng H.M., Masilamani T., Subramaniam T., Ling L.T., Radhakrishnan A.K. Rind of the rambutan, Nephelium lappaceum, a potential source of natural antioxidant. Food Chemistry 2008, 109(1):54-63.
34. Palanisamy U., Ling L.T., Manaharan T., Appleton D. Rapid isolation of geraniin from Nephelium lappaceum rind waste and its anti-hyperglycaemic activity. Food Chemistry 2011, 127:21-27.
35. Perera A., Appleton D., Loh H.Y., Elendran S., Palanisamy U.D. Large scale purification of geraniin from Nephelium lappaceum rind waste using reverse-phase chromatography. Separation and Purification Technology 2012, 98:145-149.
36. Prior R.L. Alterations in the adiposity and dyslipidaemia of obesity by berries and berry phytochemicals. Phytochemicals. Health Promotion and Therapeutic Potential 2012, 153-164. eBOOK ISBN: 978-1-4665-5162-6. C. Carkeet, K. Grann, R. Keith Randolph, D. Salter Ver (Eds.).
37. Pritchett S. Abnormal LFTs. InnovAiT 2009, 2(3):140-147.
38. Sarafidis P.A., Ruilope L.M. Insulin resistance, hyperinsulinaemia and renal injury: Mechanisms and implications. American Journal of Nephrology 2006, 26:232-244.
39. Scalbert A., Williamson G. Dietary intake and bioavailability of polyphenols. Journal of Nutrition 2000, 130:2073S-2085S.
40. Sorensen T.I.A. Challenges in the study of causation of obesity. Proceedings of the Nutrition Society 2009, 68:43-54.
41. Stark A.H., Timar B., Madar Z. Adaptation of Sprague Dalwey rats to long-term feeding of high fat or high fructose diets. European Journal of Nutrition 2000, 39:229-234.
42. Storlien L.H., Baur L.A., Kriketos A.D., Pan D.A., Cooney G.J., Jenkins A.B., Calvert G.D., Campbell L.V. Dietary fats and insulin action. Diabetiology 1996, 39:621-631.
43. Thitilertdecha N., Teerawutgulrag A., Kilburn J.D., Rakariyatham N. Identification of major phenolic compounds from Nephelium lappaceum L and their antioxidant activities. Molecules 2010, 15(3):1453-1465.
44. Wang M., Cheng H., Li Y., Meng L., Zhao G., Mai K. Herbs of the genus Phyllanthus in the treatment of chronic hepatitis B: Observations with three preparations from different geographic sites. Journal of Laboratory and Clinical Medicine 1995, 126(4):350-352.
45. Yang Y.C., Li J., Zu Y.G., Fu Y.J., Luo M., Wu N., Liu X.L. Optimisation of microwave-assisted enzymatic extraction of corilagin and geraniin from Geranium sibiricum Linne and evaluation of antioxidant activity. Food Chemistry 2010, 122:373-380.
46. Zimmet P., Alberti K.G., Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001, 414:782-787.