메뉴 건너뛰기




Volumn 525, Issue 1, 2013, Pages 18-25

Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers

Author keywords

Bmi1; Cancer stem cells; Gastric adenocarcinoma; Immunohistochemistry; Lgr5

Indexed keywords

ALDEHYDE DEHYDROGENASE; BMI1 PROTEIN; CD133 ANTIGEN; DIPEPTIDYL PEPTIDASE IV; G PROTEIN COUPLED RECEPTOR; HERMES ANTIGEN; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 5; UNCLASSIFIED DRUG;

EID: 84878878740     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.04.067     Document Type: Article
Times cited : (50)

References (37)
  • 1
    • 0027525653 scopus 로고
    • Characterization and chromosomal localization of the human proto-oncogene BMI-1
    • Alkema M.J., Wiegant J., Raap A.K., Berns A., van L.M. Characterization and chromosomal localization of the human proto-oncogene BMI-1. Hum. Mol. Genet. 1993, 2(10):1597-1603.
    • (1993) Hum. Mol. Genet. , vol.2 , Issue.10 , pp. 1597-1603
    • Alkema, M.J.1    Wiegant, J.2    Raap, A.K.3    Berns, A.4    van, L.M.5
  • 2
    • 79953676315 scopus 로고    scopus 로고
    • The role of colorectal cancer stem cells in metastatic disease and therapeutic response
    • Anderson E.C., Hessman C., Levin T.G., Monroe M.M., Wong M.H. The role of colorectal cancer stem cells in metastatic disease and therapeutic response. Cancer (Basel) 2011, 3(1):319-339.
    • (2011) Cancer (Basel) , vol.3 , Issue.1 , pp. 319-339
    • Anderson, E.C.1    Hessman, C.2    Levin, T.G.3    Monroe, M.M.4    Wong, M.H.5
  • 8
    • 33646045010 scopus 로고    scopus 로고
    • Stem cells and cancer: two faces of eve
    • Clarke M.F., Fuller M. Stem cells and cancer: two faces of eve. Cell 2006, 124(6):1111-1115.
    • (2006) Cell , vol.124 , Issue.6 , pp. 1111-1115
    • Clarke, M.F.1    Fuller, M.2
  • 9
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: premises, promises and challenges
    • Clevers H. The cancer stem cell: premises, promises and challenges. Nat. Med. 2011, 17(3):313-319.
    • (2011) Nat. Med. , vol.17 , Issue.3 , pp. 313-319
    • Clevers, H.1
  • 10
    • 33644681327 scopus 로고    scopus 로고
    • Epidemiology of gastric cancer
    • Crew K.D., Neugut A.I. Epidemiology of gastric cancer. World J. Gastroenterol. 2006, 12(3):354-362.
    • (2006) World J. Gastroenterol. , vol.12 , Issue.3 , pp. 354-362
    • Crew, K.D.1    Neugut, A.I.2
  • 12
    • 77953152285 scopus 로고    scopus 로고
    • Epidemiology of gastrointestinal and liver tumors
    • Herszenyi L., Tulassay Z. Epidemiology of gastrointestinal and liver tumors. Eur. Rev. Med. Pharmacol. Sci. 2010, 14(4):249-258.
    • (2010) Eur. Rev. Med. Pharmacol. Sci. , vol.14 , Issue.4 , pp. 249-258
    • Herszenyi, L.1    Tulassay, Z.2
  • 16
    • 84867575420 scopus 로고    scopus 로고
    • Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-β
    • Katsuno Y., Ehata S., Yashiro M., Yanagihara K., Hirakawa K., Miyazono K. Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-β. J. Pathol. 2012, 228(3):391-404.
    • (2012) J. Pathol. , vol.228 , Issue.3 , pp. 391-404
    • Katsuno, Y.1    Ehata, S.2    Yashiro, M.3    Yanagihara, K.4    Hirakawa, K.5    Miyazono, K.6
  • 17
    • 80051603461 scopus 로고    scopus 로고
    • Expression of the adult intestinal stem cell marker Lgr5 in the metastatic cascade of colorectal cancer
    • Kleist B., Xu L., Li G., Kersten C. Expression of the adult intestinal stem cell marker Lgr5 in the metastatic cascade of colorectal cancer. Int. J. Clin. Exp. Pathol. 2011, 4(4):327-335.
    • (2011) Int. J. Clin. Exp. Pathol. , vol.4 , Issue.4 , pp. 327-335
    • Kleist, B.1    Xu, L.2    Li, G.3    Kersten, C.4
  • 18
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu S., Dontu G., Mantle I.D., Patel S., Ahn N.S., et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 2006, 66(12):6063-6071.
    • (2006) Cancer Res. , vol.66 , Issue.12 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3    Patel, S.4    Ahn, N.S.5
  • 20
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky A.V., Pardal R., Iwashita T., Park I.K., Clarke M.F., Morrison S.J. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003, 425(6961):962-967.
    • (2003) Nature , vol.425 , Issue.6961 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 21
    • 84870940522 scopus 로고    scopus 로고
    • LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells
    • Nakata S., Campos B., Becker N., Engel F., Acker T. LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells. Brain Pathol. 2013, 23(1):60-72.
    • (2013) Brain Pathol. , vol.23 , Issue.1 , pp. 60-72
    • Nakata, S.1    Campos, B.2    Becker, N.3    Engel, F.4    Acker, T.5
  • 24
    • 84874265490 scopus 로고    scopus 로고
    • Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma
    • Proctor E., Waghray M., Lee C.J., Heidt D.G., Yalamanchili M., et al. Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma. PLoS One 2013, 8(2):e55820. 10.1371/journal.pone.0055820.
    • (2013) PLoS One , vol.8 , Issue.2
    • Proctor, E.1    Waghray, M.2    Lee, C.J.3    Heidt, D.G.4    Yalamanchili, M.5
  • 26
    • 33750296433 scopus 로고    scopus 로고
    • BMI-1: a protein expressed in stem cells, specialized cells and tumors of the gastrointestinal tract
    • Reinisch C., Kandutsch S., Uthman A., Pammer J. BMI-1: a protein expressed in stem cells, specialized cells and tumors of the gastrointestinal tract. Histol. Histopathol. 2006, 21(1):1143-1149.
    • (2006) Histol. Histopathol. , vol.21 , Issue.1 , pp. 1143-1149
    • Reinisch, C.1    Kandutsch, S.2    Uthman, A.3    Pammer, J.4
  • 29
    • 46249128798 scopus 로고    scopus 로고
    • Bmi1 is expressed in vivo in intestinal stem cells
    • Sangiorgi E., Capecchi M.R. Bmi1 is expressed in vivo in intestinal stem cells. Nat. Genet. 2008, 40(7):915-920.
    • (2008) Nat. Genet. , vol.40 , Issue.7 , pp. 915-920
    • Sangiorgi, E.1    Capecchi, M.R.2
  • 31
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
    • Visvader J.E., Lindeman G.J. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 2008, 8(10):755-768.
    • (2008) Nat. Rev. Cancer , vol.8 , Issue.10 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 32
    • 79951850400 scopus 로고    scopus 로고
    • Lgr5 expression and cancer stem cell hypothesis: clue to define the true origin of esophageal adenocarcinomas with and without Barrett's esophagus?
    • von Rahden B.H., Kircher S., Lazariotou M., Reiber C., Stuermer L., Otto C., Germer C.T., Grimm M. Lgr5 expression and cancer stem cell hypothesis: clue to define the true origin of esophageal adenocarcinomas with and without Barrett's esophagus?. J. Exp. Clin. Cancer Res. 2011, 30(1):23-33.
    • (2011) J. Exp. Clin. Cancer Res. , vol.30 , Issue.1 , pp. 23-33
    • von Rahden, B.H.1    Kircher, S.2    Lazariotou, M.3    Reiber, C.4    Stuermer, L.5    Otto, C.6    Germer, C.T.7    Grimm, M.8
  • 33
    • 84855948607 scopus 로고    scopus 로고
    • Expression of cancer stem cell markers ALDH1, CD44 and CD133 in primary tumor and lymph node metastasis of gastric cancer
    • Wakamatsu Y., Sakamoto N., Oo H.Z., Naito Y., Uraoka N., Anami K., Sentani K., Oue N., Yasui W. Expression of cancer stem cell markers ALDH1, CD44 and CD133 in primary tumor and lymph node metastasis of gastric cancer. Pathol. Int. 2012, 62(2):112-119.
    • (2012) Pathol. Int. , vol.62 , Issue.2 , pp. 112-119
    • Wakamatsu, Y.1    Sakamoto, N.2    Oo, H.Z.3    Naito, Y.4    Uraoka, N.5    Anami, K.6    Sentani, K.7    Oue, N.8    Yasui, W.9
  • 34
    • 79960885004 scopus 로고    scopus 로고
    • LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines
    • Walker F., Zhang H.H., Odorizzi A., Burgess A.W. LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines. PLoS One 2011, 6(7):e22733.
    • (2011) PLoS One , vol.6 , Issue.7
    • Walker, F.1    Zhang, H.H.2    Odorizzi, A.3    Burgess, A.W.4
  • 36
    • 31144445320 scopus 로고    scopus 로고
    • Incidence and mortality of gastric cancer in China
    • Yang L. Incidence and mortality of gastric cancer in China. World J. Gastroenterol. 2006, 12(1):17-20.
    • (2006) World J. Gastroenterol. , vol.12 , Issue.1 , pp. 17-20
    • Yang, L.1
  • 37
    • 34547180739 scopus 로고    scopus 로고
    • The gastrointestinal tract stem cell niche
    • Yen T.H., Wright N.A. The gastrointestinal tract stem cell niche. Stem Cell Rev. 2006, 2(3):203-212.
    • (2006) Stem Cell Rev. , vol.2 , Issue.3 , pp. 203-212
    • Yen, T.H.1    Wright, N.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.