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Volumn 21, Issue 3, 2014, Pages 134-143

Cancer and venous thromboembolic disease: From molecular mechanisms to clinical management

Author keywords

Venous thromboembolism

Indexed keywords

ACETYLSALICYLIC ACID; ANTIANEMIC AGENT; ANTICOAGULANT AGENT; ANTITHROMBIN; ANTIVITAMIN K; APIXABAN; CYTOKINE; D DIMER; DABIGATRAN; DALTEPARIN; DEXAMETHASONE; ENOXAPARIN; FONDAPARINUX; LENALIDOMIDE; NADROPARIN; PADGEM PROTEIN; PLACEBO; PROTEIN P53; PROTEINASE; RIVAROXABAN; SEMULOPARIN; THALIDOMIDE; THROMBOPLASTIN; WARFARIN;

EID: 84902656922     PISSN: None     EISSN: 17187729     Source Type: Journal    
DOI: 10.3747/co.21.1864     Document Type: Review
Times cited : (61)

References (104)
  • 1
    • 1542545008 scopus 로고    scopus 로고
    • Malignancy, thrombosis and Trousseau: The case for an eponym
    • Khorana AA. Malignancy, thrombosis and Trousseau: the case for an eponym. J Thromb Haemost 2003;1:2463-2465.
    • (2003) J Thromb Haemost , vol.1 , pp. 2463-2465
    • Khorana, A.A.1
  • 2
    • 0035876016 scopus 로고    scopus 로고
    • Molecular basis for the relationship between thrombosis and cancer
    • Rickles FR, Falanga A. Molecular basis for the relationship between thrombosis and cancer. Thromb Res 2001;102:V215-24.
    • (2001) Thromb Res , vol.102
    • Rickles, F.R.1    Falanga, A.2
  • 3
    • 34548838824 scopus 로고    scopus 로고
    • Trousseau's syndrome: Multiple definitions and multiple mechanisms
    • Varki A. Trousseau's syndrome: multiple definitions and multiple mechanisms. Blood 2007;110:1723-1729.
    • (2007) Blood , vol.110 , pp. 1723-1729
    • Varki, A.1
  • 4
    • 0020961939 scopus 로고
    • Activation of blood coagulation in cancer: Trousseau's syndrome revisited
    • Rickles FR, Edwards RL. Activation of blood coagulation in cancer: Trousseau's syndrome revisited. Blood 1983; 62: 14-31.
    • (1983) Blood , vol.62 , pp. 14-31
    • Rickles, F.R.1    Edwards, R.L.2
  • 5
    • 0026760990 scopus 로고
    • Deep-vein thrombosis and the incidence of subsequent symptomatic cancer
    • Prandoni P, Lensing AW, Buller HR, et al. Deep-vein thrombosis and the incidence of subsequent symptomatic cancer. N Engl J Med 1992; 327:1128-1133.
    • (1992) N Engl J Med , vol.327 , pp. 1128-1133
    • Prandoni, P.1    Lensing, A.W.2    Buller, H.R.3
  • 6
    • 46049090201 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition)
    • Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of venous thromboembolism: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition). Chest 2008;133(suppl):381S-453S.
    • (2008) Chest , vol.133 , Issue.SUPPL.
    • Geerts, W.H.1    Bergqvist, D.2    Pineo, G.F.3
  • 7
    • 0347537148 scopus 로고
    • Thrombosis and bleeding in cancer patients
    • Peuscher FW. Thrombosis and bleeding in cancer patients. Neth J Med 1981;24:23-35.
    • (1981) Neth J Med , vol.24 , pp. 23-35
    • Peuscher, F.W.1
  • 8
    • 0000792486 scopus 로고
    • Analysis of the autopsy records of 157 cases of carcinoma of the pancreas with particular reference to the incidence of thromboembolism
    • Thompson CM, Rodgers LR. Analysis of the autopsy records of 157 cases of carcinoma of the pancreas with particular reference to the incidence of thromboembolism. Am J Med Sci 1952;223:469-478.
    • (1952) Am J Med Sci , vol.223 , pp. 469-478
    • Thompson, C.M.1    Rodgers, L.R.2
  • 9
    • 0027933890 scopus 로고
    • Cancer and thrombosis
    • Donati MB. Cancer and thrombosis. Haemostasis 1994;24:128-31.
    • (1994) Haemostasis , vol.24 , pp. 128-131
    • Donati, M.B.1
  • 10
    • 33644981137 scopus 로고    scopus 로고
    • Venous thromboembolism in patients with colorectal cancer: Incidence and effect on survival
    • Alcalay A, Wun T, Khatri V, et al. Venous thromboembolism in patients with colorectal cancer: incidence and effect on survival. J Clin Oncol 2006; 24: 1112-1118.
    • (2006) J Clin Oncol , vol.24 , pp. 1112-1118
    • Alcalay, A.1    Wun, T.2    Khatri, V.3
  • 11
    • 33746675044 scopus 로고    scopus 로고
    • Longitudinal evaluation of health plan cost per venous thromboembolism or bleed event in patients with a prior venous thromboembolism event during hospitalization
    • Bullano M F, Willey V, Hauch O, Wygant G, Spyropoulos AC, Hoffman L. Longitudinal evaluation of health plan cost per venous thromboembolism or bleed event in patients with a prior venous thromboembolism event during hospitalization. J Manag Care Pharm 2005;11:663-673.
    • (2005) J Manag Care Pharm , vol.11 , pp. 663-673
    • Bullano, M.F.1    Willey, V.2    Hauch, O.3    Wygant, G.4    Spyropoulos, A.C.5    Hoffman, L.6
  • 12
    • 3843106898 scopus 로고    scopus 로고
    • Outcomes and cost of deep venous thrombosis among patients with cancer
    • Elting LS, Escalante CP, Cooksley C, et al. Outcomes and cost of deep venous thrombosis among patients with cancer. Arch Intern Med 2004;164:1653-1661.
    • (2004) Arch Intern Med , vol.164 , pp. 1653-1661
    • Elting, L.S.1    Escalante, C.P.2    Cooksley, C.3
  • 14
    • 0032912142 scopus 로고    scopus 로고
    • Pathophysiology of the thrombo-philic state in the cancer patient
    • Falanga A, Rickles FR. Pathophysiology of the thrombo-philic state in the cancer patient. Semin Thromb Hemost 1999;25:173-182.
    • (1999) Semin Thromb Hemost , vol.25 , pp. 173-182
    • Falanga, A.1    Rickles, F.R.2
  • 15
    • 61449137068 scopus 로고    scopus 로고
    • Overview of the postulated mechanisms linking cancer and thrombosis
    • Ten Cate H, Falanga A. Overview of the postulated mechanisms linking cancer and thrombosis. Pathophysiol Haemost Thromb 2008;36:122-130.
    • (2008) Pathophysiol Haemost Thromb , vol.36 , pp. 122-130
    • Ten Cate, H.1    Falanga, A.2
  • 16
    • 33748454321 scopus 로고    scopus 로고
    • Mechanisms of cancer-induced thrombosis in cancer
    • Rickles FR. Mechanisms of cancer-induced thrombosis in cancer. Pathophysiol Haemost Thromb 2006;35:103-110.
    • (2006) Pathophysiol Haemost Thromb , vol.35 , pp. 103-110
    • Rickles, F.R.1
  • 19
    • 0035654918 scopus 로고    scopus 로고
    • The pleiotropic effects of tissue factor: A possible role for factor viia-induced intracellular signalling?
    • Versteeg HH, Peppelenbosch MP, Spek CA. The pleiotropic effects of tissue factor: a possible role for factor viia-induced intracellular signalling? Thromb Haemost 2001;86:1353-1359.
    • (2001) Thromb Haemost , vol.86 , pp. 1353-1359
    • Versteeg, H.H.1    Peppelenbosch, M.P.2    Spek, C.A.3
  • 20
    • 77949263041 scopus 로고    scopus 로고
    • Cellular sources of tissue factor in endotoxemia and sepsis
    • Pawlinski R, Mackman N. Cellular sources of tissue factor in endotoxemia and sepsis. Thromb Res 2010;125(suppl 1):S70-S73.
    • (2010) Thromb Res , vol.125 , Issue.SUPPL. 1
    • Pawlinski, R.1    Mackman, N.2
  • 21
    • 84856283500 scopus 로고    scopus 로고
    • The relationship between tissue factor and cancer progression: Insights from bench and bedside
    • van den Berg YW, Osanto S, Reitsma PH, Versteeg HH. The relationship between tissue factor and cancer progression: insights from bench and bedside. Blood 2012;119: 924-932.
    • (2012) Blood , vol.119 , pp. 924-932
    • van den Berg, Y.W.1    Osanto, S.2    Reitsma, P.H.3    Versteeg, H.H.4
  • 22
    • 4644312977 scopus 로고    scopus 로고
    • Cross-talk of integr in α3β1 and tissue factor in cell migration
    • Dorfeutner A, Hintermann E, Tarui T, Takada Y, Ruf W. Cross-talk of integr in α3β1 and tissue factor in cell migration. Mol Biol Cell 2004; 15: 4416-4425.
    • (2004) Mol Biol Cell , vol.15 , pp. 4416-4425
    • Dorfeutner, A.1    Hintermann, E.2    Tarui, T.3    Takada, Y.4    Ruf, W.5
  • 23
    • 78650634323 scopus 로고    scopus 로고
    • Cooperation of tissue factor cytoplasmic domain and par2 signaling in breast cancer development
    • Schaffner F, Versteeg HH, Schillert A, et al. Cooperation of tissue factor cytoplasmic domain and par2 signaling in breast cancer development. Blood 2010;116:6106-6113.
    • (2010) Blood , vol.116 , pp. 6106-6113
    • Schaffner, F.1    Versteeg, H.H.2    Schillert, A.3
  • 24
    • 84887361291 scopus 로고    scopus 로고
    • Tumor-derived tissue factor-positive microparticles and venous thrombosis in cancer patients
    • Geddings JE, Mackman N. Tumor-derived tissue factor-positive microparticles and venous thrombosis in cancer patients. Blood 2013;122:1873-1880.
    • (2013) Blood , vol.122 , pp. 1873-1880
    • Geddings, J.E.1    Mackman, N.2
  • 25
    • 0022339529 scopus 로고
    • Isolation and characterization of cancer procoagulant: A cysteine proteinase from malignant tissue
    • Falanga A, Gordon SG. Isolation and characterization of cancer procoagulant: a cysteine proteinase from malignant tissue. Biochemistry 1985;24:5558-5567.
    • (1985) Biochemistry , vol.24 , pp. 5558-5567
    • Falanga, A.1    Gordon, S.G.2
  • 26
    • 0026462546 scopus 로고
    • The plasminogen-plasmin system in malignancy
    • Kwaan HC. The plasminogen-plasmin system in malignancy. Cancer Metastasis Rev 1992;11: 291-311.
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 291-311
    • Kwaan, H.C.1
  • 27
    • 1542287347 scopus 로고    scopus 로고
    • Neutrophil extracellular traps kill bacteria
    • Brinkmann V, Reichard U, Goosmann C, et al. Neutrophil extracellular traps kill bacteria. Science 2004;303:1532-1535.
    • (2004) Science , vol.303 , pp. 1532-1535
    • Brinkmann, V.1    Reichard, U.2    Goosmann, C.3
  • 29
    • 84871505285 scopus 로고    scopus 로고
    • Thrombosis as an intravascular effector of innate immunity
    • Engelmann B, Massberg S. Thrombosis as an intravascular effector of innate immunity. Nat Rev Immunol 2013;13:34-45.
    • (2013) Nat Rev Immunol , vol.13 , pp. 34-45
    • Engelmann, B.1    Massberg, S.2
  • 30
    • 84864650304 scopus 로고    scopus 로고
    • Cancers predispose neutrophils to release extracellular dna traps that contribute to cancer-associated thrombosis
    • Demers M, Krause DS, Schatzberg D, et al. Cancers predispose neutrophils to release extracellular dna traps that contribute to cancer-associated thrombosis. Proc Natl Acad Sci U S A 2012;109:13076-130981.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 13076-130981
    • Demers, M.1    Krause, D.S.2    Schatzberg, D.3
  • 31
    • 84875164566 scopus 로고    scopus 로고
    • Mechanisms of thrombosis in cancer
    • Falanga A, Russo L, Verzeroli C. Mechanisms of thrombosis in cancer. Thromb Res 2013;131(suppl 1):S59-S62.
    • (2013) Thromb Res , vol.131 , Issue.SUPPL. 1
    • Falanga, A.1    Russo, L.2    Verzeroli, C.3
  • 32
    • 36049000503 scopus 로고    scopus 로고
    • Frequency, risk factors, and trends for venous throm-boembolism among hospitalized cancer patients
    • Khorana AA, Francis CW, Culakova E, Kuderer NM, Lyman GH. Frequency, risk factors, and trends for venous throm-boembolism among hospitalized cancer patients. Cancer 2007;110:2339-2346.
    • (2007) Cancer , vol.110 , pp. 2339-2346
    • Khorana, A.A.1    Francis, C.W.2    Culakova, E.3    Kuderer, N.M.4    Lyman, G.H.5
  • 33
    • 13444256137 scopus 로고    scopus 로고
    • Malig nancies, prothrombotic mutations, and the risk of venous thrombosis
    • Blom J W, Doggen CJ, Osanto S, Rosendaal FR. Malig nancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA 2005;293:715-722.
    • (2005) JAMA , vol.293 , pp. 715-722
    • Blom, J.W.1    Doggen, C.J.2    Osanto, S.3    Rosendaal, F.R.4
  • 34
    • 0036213529 scopus 로고    scopus 로고
    • Venous thrombosis in patients with solid tumors: Determination of frequency and characteristics
    • Sallah S, Wan JY, Nguyen N P. Venous thrombosis in patients with solid tumors: determination of frequency and characteristics. Thromb Haemost 2002;87:575-579.
    • (2002) Thromb Haemost , vol.87 , pp. 575-579
    • Sallah, S.1    Wan, J.Y.2    Nguyen, N.P.3
  • 35
    • 29144486069 scopus 로고    scopus 로고
    • Risk factors for chemotherapy-associated venous thromboembolism in a prospective observational study
    • Khorana AA, Francis CW, Culakova E, Lyman GH. Risk factors for chemotherapy-associated venous thromboembolism in a prospective observational study. Cancer 2005;104:2822-2829.
    • (2005) Cancer , vol.104 , pp. 2822-2829
    • Khorana, A.A.1    Francis, C.W.2    Culakova, E.3    Lyman, G.H.4
  • 36
    • 84865252869 scopus 로고    scopus 로고
    • Incidence, risk factors and clinical features of venous thromboembolism in newly diagnosed lymphoma patients: Results from a prospective cohort study with Asian population
    • Park LC, Woo SY, Kim S, et al. Incidence, risk factors and clinical features of venous thromboembolism in newly diagnosed lymphoma patients: results from a prospective cohort study with Asian population. Thromb Res 2012;130:e6-e12.
    • (2012) Thromb Res , vol.130
    • Park, L.C.1    Woo, S.Y.2    Kim, S.3
  • 37
    • 54149109726 scopus 로고    scopus 로고
    • Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer
    • Khorana AA, Francis CW, Menzies KE, et al. Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer. J Thromb Haemost 2008; 6: 1983-1985.
    • (2008) J Thromb Haemost , vol.6 , pp. 1983-1985
    • Khorana, A.A.1    Francis, C.W.2    Menzies, K.E.3
  • 38
    • 68949083519 scopus 로고    scopus 로고
    • Thromboembolism in patients with advanced gastroesophageal cancer treated with anthracycline, platinum, and fuoropyrimidine combination chemotherapy: A report from the UK National Cancer Research Institute Upper Gastrointestinal Clinical Studies Group
    • Starling N, Rao S, Cunningham D, et al. Thromboembolism in patients with advanced gastroesophageal cancer treated with anthracycline, platinum, and fuoropyrimidine combination chemotherapy: a report from the UK National Cancer Research Institute Upper Gastrointestinal Clinical Studies Group. J Clin Oncol 2009;27:3786-3793.
    • (2009) J Clin Oncol , vol.27 , pp. 3786-3793
    • Starling, N.1    Rao, S.2    Cunningham, D.3
  • 41
    • 0141973788 scopus 로고    scopus 로고
    • Venous thromboembolism associated with long-term use of central venous catheters in cancer patients
    • Verso M, Agnelli G. Venous thromboembolism associated with long-term use of central venous catheters in cancer patients. J Clin Oncol 2003;21:3665-3675.
    • (2003) J Clin Oncol , vol.21 , pp. 3665-3675
    • Verso, M.1    Agnelli, G.2
  • 42
    • 40349103260 scopus 로고    scopus 로고
    • Venous throm -boembolism and mortality associated with recombinant eryth-ropoietin and darbepoetin administration for the treatment of cancer-associated anemia
    • Bennett CL, Silver SM, Djulbegovic B, et al. Venous throm -boembolism and mortality associated with recombinant eryth-ropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA 2008; 299:914-924.
    • (2008) JAMA , vol.299 , pp. 914-924
    • Bennett, C.L.1    Silver, S.M.2    Djulbegovic, B.3
  • 44
    • 70249119693 scopus 로고    scopus 로고
    • D-Dimer and prothrom-bin fragment 1+2 predict venous thromboembolism in patients with cancer: Results from the Vienna Cancer and Thrombosis Study
    • Ay C, Vormittag R, Dunkler D, et al. D-Dimer and prothrom-bin fragment 1+2 predict venous thromboembolism in patients with cancer: results from the Vienna Cancer and Thrombosis Study. J Clin Oncol 2009; 27:4124-9.
    • (2009) J Clin Oncol , vol.27 , pp. 4124-4129
    • Ay, C.1    Vormittag, R.2    Dunkler, D.3
  • 45
    • 84883661937 scopus 로고    scopus 로고
    • Venous throm -boembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update
    • Lyman GH, Khorana AA, Kuderer NM, et al. Venous throm -boembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol 2013;31:2189-2204.
    • (2013) J Clin Oncol , vol.31 , pp. 2189-2204
    • Lyman, G.H.1    Khorana, A.A.2    Kuderer, N.M.3
  • 46
    • 43449115194 scopus 로고    scopus 로고
    • Development and validation of a predictive model for chemotherapy-associated thrombosis
    • Khorana AA, Kuderer NM, Culakova E, Lyman GH, Francis CW. Development and validation of a predictive model for chemotherapy-associated thrombosis. Blood 2008; 111: 4902-4907.
    • (2008) Blood , vol.111 , pp. 4902-4907
    • Khorana, A.A.1    Kuderer, N.M.2    Culakova, E.3    Lyman, G.H.4    Francis, C.W.5
  • 47
    • 0042709550 scopus 로고    scopus 로고
    • Venou s thrombosis in cancer patients: Insights from the frontline survey
    • Kakkar A K, Levine M, Pinedo H M, Wolf f R, Wong J. Venou s thrombosis in cancer patients: insights from the frontline survey. Oncologist 2003;8:381-388.
    • (2003) Oncologist , vol.8 , pp. 381-388
    • Kakkar, A.K.1    Levine, M.2    Pinedo, H.M.3    Wolff, R.4    Wong, J.5
  • 48
    • 84883661937 scopus 로고    scopus 로고
    • Venous throm -boembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update
    • Lyman GH, Khorana AA, Kuderer NM, et al. Venous throm -boembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol 2013;31:2189-2204.
    • (2013) J Clin Oncol , vol.31 , pp. 2189-2204
    • Lyman, G.H.1    Khorana, A.A.2    Kuderer, N.M.3
  • 49
    • 32844466981 scopus 로고    scopus 로고
    • Efficacy and safety of fondaparinux for the prevention of venous thromboem-bolism in older acute medical patients: Randomised placebo controlled trial
    • Cohen AT, Davidson BL, Gallus AS, et al. Efficacy and safety of fondaparinux for the prevention of venous thromboem-bolism in older acute medical patients: randomised placebo controlled trial. BMJ 2006;332:325-359.
    • (2006) BMJ , vol.332 , pp. 325-359
    • Cohen, A.T.1    Davidson, B.L.2    Gallus, A.S.3
  • 50
    • 4143085802 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients
    • Goldhaber SZ on behalf of the prevent Medical Thromboprophylaxis Study Group
    • Leizorovicz A, Cohen AT, Turpie AG, Olsson CG, Vait-kus PT, Goldhaber SZ on behalf of the prevent Medical Thromboprophylaxis Study Group. Randomized, placebo-controlled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients. Circulation 2004;110:874-879.
    • (2004) Circulation , vol.110 , pp. 874-879
    • Leizorovicz, A.1    Cohen, A.T.2    Turpie, A.G.3    Olsson, C.G.4    Vait-Kus, P.T.5
  • 51
    • 0033539025 scopus 로고    scopus 로고
    • A comparison of enoxaparin with placebo for the prevention of venous th romboembolism in acutely ill medical patients. Prophylaxis in Medical Patients with Enoxaparin Study Group
    • Samama MM, Cohen AT, Darmon JY, et al. A comparison of enoxaparin with placebo for the prevention of venous th romboembolism in acutely ill medical patients. Prophylaxis in Medical Patients with Enoxaparin Study Group. N Engl J Med 1999;341:793-800.
    • (1999) N Engl J Med , vol.341 , pp. 793-800
    • Samama, M.M.1    Cohen, A.T.2    Darmon, J.Y.3
  • 52
    • 36849085802 scopus 로고    scopus 로고
    • The nccn clinical practice guidelines on venous thromboembolic disease: Strategies for improving vte prophylaxis in hospitalized cancer patients
    • Khorana AA. The nccn clinical practice guidelines on venous thromboembolic disease: strategies for improving vte prophylaxis in hospitalized cancer patients. Oncologist 2007;12:1361-1370.
    • (2007) Oncologist , vol.12 , pp. 1361-1370
    • Khorana, A.A.1
  • 53
    • 34447634273 scopus 로고    scopus 로고
    • Thromboprophylaxis rates in US medical centers: Success or failure?
    • Amin A, Stemkowski S, Lin J, Yang G. Thromboprophylaxis rates in US medical centers: success or failure? J Thromb Haemost 2007; 5:1610-1616.
    • (2007) J Thromb Haemost , vol.5 , pp. 1610-1616
    • Amin, A.1    Stemkowski, S.2    Lin, J.3    Yang, G.4
  • 54
    • 33750539316 scopus 로고    scopus 로고
    • Thromboprophylaxis in medically ill patients at risk for venous thromboembolism
    • Burleigh E, Wang C, Foster D, et al. Thromboprophylaxis in medically ill patients at risk for venous thromboembolism. Am J Health Syst Pharm 2006;63(suppl 6):S23-S29.
    • (2006) Am J Health Syst Pharm , vol.63 , Issue.SUPPL. 6
    • Burleigh, E.1    Wang, C.2    Foster, D.3
  • 56
    • 34548674220 scopus 로고    scopus 로고
    • Venous thrombo-embolism in patients with active cancer
    • Seddighzadeh A, Shetty R, Goldhaber SZ. Venous thrombo-embolism in patients with active cancer. Thromb Haemost 2007;98:656-661.
    • (2007) Thromb Haemost , vol.98 , pp. 656-661
    • Seddighzadeh, A.1    Shetty, R.2    Goldhaber, S.Z.3
  • 57
    • 70350705004 scopus 로고    scopus 로고
    • Prevention of thrombosis in ambulatory patients with cancer
    • Rana P, Levine MN. Prevention of thrombosis in ambulatory patients with cancer. J Clin Oncol 2009;27:4885-4888.
    • (2009) J Clin Oncol , vol.27 , pp. 4885-4888
    • Rana, P.1    Levine, M.N.2
  • 58
    • 0028296769 scopus 로고
    • Double-blind randomised trial of a very-low-dose warfarin for prevention of thrombo-embolism in stage iv breast cancer
    • Levine M, Hirsh J, Gent M, et al. Double-blind randomised trial of a very-low-dose warfarin for prevention of thrombo-embolism in stage iv breast cancer. Lancet 1994;343:886-889.
    • (1994) Lancet , vol.343 , pp. 886-889
    • Levine, M.1    Hirsh, J.2    Gent, M.3
  • 60
    • 84857129296 scopus 로고    scopus 로고
    • Semuloparin for thromboprophylaxis in patients receiving chemotherapy for cancer
    • Agnelli G, George DJ, Kakkar AK, et al. Semuloparin for thromboprophylaxis in patients receiving chemotherapy for cancer. N Engl J Med 2012;366:601-609.
    • (2012) N Engl J Med , vol.366 , pp. 601-609
    • Agnelli, G.1    George, D.J.2    Kakkar, A.K.3
  • 61
    • 84861334022 scopus 로고    scopus 로고
    • Gemcitabine versus gemcitabine plus dalteparin thromboprophylaxis in pancreatic cancer
    • Maraveyas A, Waters J, Roy R, et al. Gemcitabine versus gemcitabine plus dalteparin thromboprophylaxis in pancreatic cancer. Eur J Cancer 2012;48:1283-92.
    • (2012) Eur J Cancer , vol.48 , pp. 1283-1292
    • Maraveyas, A.1    Waters, J.2    Roy, R.3
  • 62
    • 58149377600 scopus 로고    scopus 로고
    • Rationale and design of prospect-conko 004: A prospective, randomized trial of simultaneous pancreatic cancer treatment with enoxaparin and chemotherapy
    • Riess H, Pelzer U, Hilbig A, et al. Rationale and design of prospect-conko 004: a prospective, randomized trial of simultaneous pancreatic cancer treatment with enoxaparin and chemotherapy. BMC Cancer 2008;8: 361.
    • (2008) BMC Cancer , vol.8 , pp. 361
    • Riess, H.1    Pelzer, U.2    Hilbig, A.3
  • 63
    • 0141651863 scopus 로고    scopus 로고
    • Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures
    • White RH, Zhou H, Romano PS. Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures. Thromb Haemost 2003;90:446-455.
    • (2003) Thromb Haemost , vol.90 , pp. 446-455
    • White, R.H.1    Zhou, H.2    Romano, P.S.3
  • 64
    • 0026588954 scopus 로고
    • Postoperative pulmonary embolism after hospital discharge. An underestimated risk
    • Huber O, Bounameaux H, Borst F, Rohner A. Postoperative pulmonary embolism after hospital discharge. An underestimated risk. Arch Surg 1992;127:310-13.
    • (1992) Arch Surg , vol.127 , pp. 310-313
    • Huber, O.1    Bounameaux, H.2    Borst, F.3    Rohner, A.4
  • 65
    • 30144440519 scopus 로고    scopus 로고
    • A clinical outcome-based prospective study on venous thromboembolism after cancer surgery: The @ristos project
    • Agnelli G, Bolis G, Capussotti L, et al. A clinical outcome-based prospective study on venous thromboembolism after cancer surgery: the @ristos project. Ann Surg 2006;243:89-95.
    • (2006) Ann Surg , vol.243 , pp. 89-95
    • Agnelli, G.1    Bolis, G.2    Capussotti, L.3
  • 66
    • 0035668874 scopus 로고    scopus 로고
    • Meta-a nalysis of low molecular weight heparin in the pre -vention of venous thromboembolism in general surgery
    • Mismetti P, Laporte S, Darmon JY, Buchmuller A, Decousus H. Meta-a nalysis of low molecular weight heparin in the pre -vention of venous thromboembolism in general surgery. Br J Surg 2001;88:913-930.
    • (2001) Br J Surg , vol.88 , pp. 913-930
    • Mismetti, P.1    Laporte, S.2    Darmon, J.Y.3    Buchmuller, A.4    Decousus, H.5
  • 67
    • 31344453009 scopus 로고    scopus 로고
    • Towards evidence-based guidelines for the prevention of venous thrombo-embolism: Systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis
    • Roderick P, Ferris G, Wilson K, et al. Towards evidence-based guidelines for the prevention of venous thrombo-embolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis. Health Technol Assess 2005;9:iii-iv, ix-x,1-78.
    • (2005) Health Technol Assess , vol.9 , pp. 1-78
    • Roderick, P.1    Ferris, G.2    Wilson, K.3
  • 68
    • 33745909893 scopus 로고    scopus 로고
    • Cyprus Cardiovascular Disease Educational and Research Trust, European Venous Forum, International Surgical Thrombosis Forum, International Union of Angiology, and Union Internationale de Phlébologie
    • Cardiovascular Disease Educational and Research Trust
    • Cardiovascular Disease Educational and Research Trust, Cyprus Cardiovascular Disease Educational and Research Trust, European Venous Forum, International Surgical Thrombosis Forum, International Union of Angiology, and Union Internationale de Phlébologie. Prevention and treatment of venous thromboembolism. International consensus statement (guidelines according to scientifc evidence). Int Angiol 2006;25:101-161.
    • (2006) Prevention and Treatment of Venous Thromboembolism. International Consensus Statement (guidelines According to Scientifc Evidence) , vol.25 , pp. 101-161
  • 69
    • 0037187892 scopus 로고    scopus 로고
    • On behalf of the enoxacan ii investigators. Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer
    • Bergqvist D, Agnelli G, Cohen AT, et al. On behalf of the enoxacan ii investigators. Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer. N Engl J Med 2002;346:975-980.
    • (2002) N Engl J Med , vol.346 , pp. 975-980
    • Bergqvist, D.1    Agnelli, G.2    Cohen, A.T.3
  • 70
    • 33750051333 scopus 로고    scopus 로고
    • Prolonged prophylaxis with daltepar i n to prevent late thromboem-bolic complications in patients undergoing major abdominal surgery: A multicenter randomized open-label study
    • Rasmussen MS, Jorgensen LN, Wille-Jorgensen P, et al. Prolonged prophylaxis with daltepar i n to prevent late thromboem-bolic complications in patients undergoing major abdominal surgery: a multicenter randomized open-label study. J Thromb Haemost 2006;4:2384-2390.
    • (2006) J Thromb Haemost , vol.4 , pp. 2384-2390
    • Rasmussen, M.S.1    Jorgensen, L.N.2    Wille-Jorgensen, P.3
  • 71
    • 33746653728 scopus 로고    scopus 로고
    • On behalf of the FX140 study investigators. A randomized study comparing the efficacy and safety of nadroparin 2850 IU (0.3 mL) vs. enoxaparin 4000 IU (40 mg) in the prevention of venous thromboembolism after colorectal surgery for cancer
    • Simonneau G, Laporte S, Mismetti P, et al. On behalf of the FX140 study investigators. A randomized study comparing the efficacy and safety of nadroparin 2850 IU (0.3 mL) vs. enoxaparin 4000 IU (40 mg) in the prevention of venous thromboembolism after colorectal surgery for cancer. J Thromb Haemost 2006;4:1693-1700.
    • (2006) J Thromb Haemost , vol.4 , pp. 1693-1700
    • Simonneau, G.1    Laporte, S.2    Mismetti, P.3
  • 72
    • 0037775584 scopus 로고    scopus 로고
    • Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer
    • Lee AY, Levine MN, Baker RI, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med 2003;349:146-153.
    • (2003) N Engl J Med , vol.349 , pp. 146-153
    • Lee, A.Y.1    Levine, M.N.2    Baker, R.I.3
  • 73
    • 84883765106 scopus 로고    scopus 로고
    • Management of challenging cases of patients with cancer associated thrombosis including recurrent thrombosis and bleeding: Guidance from the ssc of the isth
    • Lee AY on behalf of the Subcommittee on Haemostasis and Malignancy for the ssc of the isth
    • Carrier M, Khorana AA, Zwicker J, Noble S, Lee AY on behalf of the Subcommittee on Haemostasis and Malignancy for the ssc of the isth. Management of challenging cases of patients with cancer associated thrombosis including recurrent thrombosis and bleeding: guidance from the ssc of the isth. J Thromb Haemost 2013; 11: 1760-1765.
    • (2013) J Thromb Haemost , vol.11 , pp. 1760-1765
    • Carrier, M.1    Khorana, A.A.2    Zwicker, J.3    Noble, S.4
  • 74
    • 0029925784 scopus 로고    scopus 로고
    • Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: Results of a meta-analysis
    • Siragusa S, Cosmi B, Piovella F, Hirsh J, Ginsberg JS. Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: results of a meta-analysis. Am J Med 1996;100:269-277.
    • (1996) Am J Med , vol.100 , pp. 269-277
    • Siragusa, S.1    Cosmi, B.2    Piovella, F.3    Hirsh, J.4    Ginsberg, J.S.5
  • 76
    • 10844249206 scopus 로고    scopus 로고
    • Low-molecular-weight heparin and cancer survival: Review of the literature and pooled analysis of 1,726 patients treated for at least three months
    • Conti S, Guercini F, Iorio A. Low-molecular-weight heparin and cancer survival: review of the literature and pooled analysis of 1,726 patients treated for at least three months. Pathophysiol Haemost Thromb 2004;33:197-201.
    • (2004) Pathophysiol Haemost Thromb , vol.33 , pp. 197-201
    • Conti, S.1    Guercini, F.2    Iorio, A.3
  • 77
    • 0037067889 scopus 로고    scopus 로고
    • Comparison of low-molecular-weight heparin and warfarin for the secondary prevention of venous thromboembolism in patients with cancer: A randomized controlled study
    • Meyer G, Marjanovic Z, Valcke J, et al. Comparison of low-molecular-weight heparin and warfarin for the secondary prevention of venous thromboembolism in patients with cancer: a randomized controlled study. Arch Intern Med 2002;162:1729-1735.
    • (2002) Arch Intern Med , vol.162 , pp. 1729-1735
    • Meyer, G.1    Marjanovic, Z.2    Valcke, J.3
  • 78
    • 79958133036 scopus 로고    scopus 로고
    • Long-term anticoagulation treatment for acute venous thromboembolism in patients with and without cancer. The Swiss Venous Thromboembolism Registry (swivter) ii
    • Spirk D, Ugi J, Korte W, et al. Long-term anticoagulation treatment for acute venous thromboembolism in patients with and without cancer. The Swiss Venous Thromboembolism Registry (swivter) ii. Thromb Haemost 2011;105: 962-967.
    • (2011) Thromb Haemost , vol.105 , pp. 962-967
    • Spirk, D.1    Ugi, J.2    Korte, W.3
  • 80
    • 70350726563 scopus 로고    scopus 로고
    • New antithrombotic drugs: Potential for use in oncology
    • Levine MN. New antithrombotic drugs: potential for use in oncology. J Clin Oncol 2009; 27: 4912-4918.
    • (2009) J Clin Oncol , vol.27 , pp. 4912-4918
    • Levine, M.N.1
  • 81
    • 84880327613 scopus 로고    scopus 로고
    • On behalf of the amplify investigators. Oral apixaban for the treatment of acute venous thromboembolism
    • Agnelli G, Buller HR, Cohen A, et al. On behalf of the amplify investigators. Oral apixaban for the treatment of acute venous thromboembolism N Engl J Med 2013;369:799-808.
    • (2013) N Engl J Med , vol.369 , pp. 799-808
    • Agnelli, G.1    Buller, H.R.2    Cohen, A.3
  • 82
    • 84873514413 scopus 로고    scopus 로고
    • On behalf of the magellan investigators. R ivaroxaban for th romboprophylaxis in acutely ill medical patients
    • Cohen AT, Spiro TE, Buller HR, et al. On behalf of the magellan investigators. R ivaroxaban for th romboprophylaxis in acutely ill medical patients. N Engl J Med 2013;368:513-523.
    • (2013) N Engl J Med , vol.368 , pp. 513-523
    • Cohen, A.T.1    Spiro, T.E.2    Buller, H.R.3
  • 83
    • 78650619315 scopus 로고    scopus 로고
    • On behalf of the einstein investigators. Oral rivaroxaban for symptomatic venous thromboembolism
    • Bauersachs R, Berkowitz SD, Brenner B, et al. On behalf of the einstein investigators. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med 2010;363:2499-2510.
    • (2010) N Engl J Med , vol.363 , pp. 2499-2510
    • Bauersachs, R.1    Berkowitz, S.D.2    Brenner, B.3
  • 84
    • 84859385808 scopus 로고    scopus 로고
    • On behalf of the einstein-peinvestigat or s. Oralrivaroxaba n for t he treatment of symptom-atic pulmonary embolism
    • Büller H R, Prins MH, Lensin AW, et al. On behalf of the einstein-peinvestigat or s. Oralrivaroxaba n for t he treatment of symptom-atic pulmonary embolism. N Engl J Med 2012;366:1287-1297.
    • (2012) N Engl J Med , vol.366 , pp. 1287-1297
    • Büller, H.R.1    Prins, M.H.2    Lensin, A.W.3
  • 85
    • 71849117615 scopus 로고    scopus 로고
    • On behalf of the re-cover study group. Dabigatran versus warfarin in the treatment of acute venous thromboembolism
    • Schulman S, Kearon C, Kakkar AK, et al. On behalf of the re-cover study group. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009;361:2342-2352.
    • (2009) N Engl J Med , vol.361 , pp. 2342-2352
    • Schulman, S.1    Kearon, C.2    Kakkar, A.K.3
  • 86
    • 79960638184 scopus 로고    scopus 로고
    • How to prevent, treat, and overcome current clinical challenges of vte
    • Van Es J, Eerenberg ES, Kamphuisen PW, Buller HR. How to prevent, treat, and overcome current clinical challenges of vte. J Thromb Haemost 2011;9(suppl 1):265-274.
    • (2011) J Thromb Haemost , vol.9 , Issue.SUPPL. 1 , pp. 265-274
    • van Es, J.1    Eerenberg, E.S.2    Kamphuisen, P.W.3    Buller, H.R.4
  • 87
    • 63649105562 scopus 로고    scopus 로고
    • Does antithrom-botic therapy improve survival in cancer patients?
    • Cunningham MS, Preston RJ, O'Donnell JS. Does antithrom-botic therapy improve survival in cancer patients? Blood Rev 2009; 23:129-135.
    • (2009) Blood Rev , vol.23 , pp. 129-135
    • Cunningham, M.S.1    Preston, R.J.2    O'Donnell, J.S.3
  • 89
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin SR. Thrombin signalling and protease-activated receptors. Nature 2000;407:258-264.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 90
    • 84892564980 scopus 로고    scopus 로고
    • Activated factor x signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells
    • Gleeson EM, O'Donnell JS, Hams E, et al. Activated factor x signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells. Haematologica 2014;99:185-193.
    • (2014) Haematologica , vol.99 , pp. 185-193
    • Gleeson, E.M.1    O'Donnell, J.S.2    Hams, E.3
  • 91
    • 33645108875 scopus 로고    scopus 로고
    • Thrombin/thrombin receptor (par-1)-mediated induction of IL-8 and vegf expression in prostate cancer cells
    • Liu J, Schuff-Werner P, Steiner M. Thrombin/thrombin receptor (par-1)-mediated induction of IL-8 and vegf expression in prostate cancer cells. Biochem Biophys Res Commun 2006;343:183-189.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 183-189
    • Liu, J.1    Schuff-Werner, P.2    Steiner, M.3
  • 92
    • 31544450986 scopus 로고    scopus 로고
    • Protease-activated receptor-2 is essential for factor viia and xa-induced signaling, migration, and invasion of breast cancer cells
    • Morris DR, Ding Y, Ricks TK, Gullapalli A, Wolfe BL, Trejo J. Protease-activated receptor-2 is essential for factor viia and xa-induced signaling, migration, and invasion of breast cancer cells. Cancer Res 2006;66:307-314.
    • (2006) Cancer Res , vol.66 , pp. 307-314
    • Morris, D.R.1    Ding, Y.2    Ricks, T.K.3    Gullapalli, A.4    Wolfe, B.L.5    Trejo, J.6
  • 93
    • 0034669975 scopus 로고    scopus 로고
    • Fibrinogen is an important determinant of the metastatic potential of circulating tumor cells
    • Palumbo JS, Kombrinck KW, Drew AF, et al. Fibrinogen is an important determinant of the metastatic potential of circulating tumor cells. Blood 2000;96:3302-3309.
    • (2000) Blood , vol.96 , pp. 3302-3309
    • Palumbo, J.S.1    Kombrinck, K.W.2    Drew, A.F.3
  • 94
    • 0035749852 scopus 로고    scopus 로고
    • Fibrinogen and tumor cell metastasis
    • Palumbo JS, Degen JL. Fibrinogen and tumor cell metastasis. Haemostasis 2001;31(suppl 1):11-15.
    • (2001) Haemostasis , vol.31 , Issue.SUPPL. 1 , pp. 11-15
    • Palumbo, J.S.1    Degen, J.L.2
  • 95
    • 70350433591 scopus 로고    scopus 로고
    • Anti-cancer properties of low-molecular-weight heparin: Preclinical evidence
    • Mousa SA, Petersen LJ. Anti-cancer properties of low-molecular-weight heparin: preclinical evidence. Thromb Haemost 2009;102:258-267.
    • (2009) Thromb Haemost , vol.102 , pp. 258-267
    • Mousa, S.A.1    Petersen, L.J.2
  • 96
    • 35948980396 scopus 로고    scopus 로고
    • P-selectin- and hepa-ranase-dependent antimet a static activity of non-anticoagulant heparins
    • Hostettler N, Naggi A, Torri G, et al. P-selectin- and hepa-ranase-dependent antimet a static activity of non-anticoagulant heparins. FAS EB J 2007;21:3562-3572.
    • (2007) FAS EB J , vol.21 , pp. 3562-3572
    • Hostettler, N.1    Naggi, A.2    Torri, G.3
  • 97
    • 0242469234 scopus 로고    scopus 로고
    • Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight
    • Khorana AA, Sahni A, Altland OD, Francis CW. Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight. Arterioscler Thromb Vasc Biol 2003; 23: 2110-2115.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 2110-2115
    • Khorana, A.A.1    Sahni, A.2    Altland, O.D.3    Francis, C.W.4
  • 99
    • 33846847643 scopus 로고    scopus 로고
    • In vitro study of low molecular weight heparin effect on cell growth and cell invasion in primary cell cultures of high-grade gliomas
    • Balzarotti M, Fontana F, Marras C, et al. In vitro study of low molecular weight heparin effect on cell growth and cell invasion in primary cell cultures of high-grade gliomas. Oncol Res 2006;16: 245-250.
    • (2006) Oncol Res , vol.16 , pp. 245-250
    • Balzarotti, M.1    Fontana, F.2    Marras, C.3
  • 100
    • 0035748982 scopus 로고    scopus 로고
    • Effect of heparin on apoptosis in human nasopharyngeal carcinoma CNE2 cells
    • Li HL, Ye KH, Zhang HW, et al. Effect of heparin on apoptosis in human nasopharyngeal carcinoma CNE2 cells. Cell Res 2001;11: 311-315.
    • (2001) Cell Res , vol.11 , pp. 311-315
    • Li, H.L.1    Ye, K.H.2    Zhang, H.W.3
  • 101
    • 3042704507 scopus 로고    scopus 로고
    • Low molecular weight heparin, therapy with dalteparin, and sur vival in adva nced cancer: The fragmin advanced malignancy outcome study (famous)
    • Kakkar AK, Levine MN, Kadziola Z, et al. Low molecular weight heparin, therapy with dalteparin, and sur vival in adva nced cancer: the fragmin advanced malignancy outcome study (famous). J Clin Oncol 2004;22:1944-1948.
    • (2004) J Clin Oncol , vol.22 , pp. 1944-1948
    • Kakkar, A.K.1    Levine, M.N.2    Kadziola, Z.3
  • 102
    • 20244376337 scopus 로고    scopus 로고
    • The effect of low molecular weight heparin on survival in patients with advanced malignancy
    • Klerk CP, Smorenburg SM, Otten HM, et al. The effect of low molecular weight heparin on survival in patients with advanced malignancy. J Clin Oncol 2005;23:2130-2135.
    • (2005) J Clin Oncol , vol.23 , pp. 2130-2135
    • Klerk, C.P.1    Smorenburg, S.M.2    Otten, H.M.3
  • 103
    • 34548169044 scopus 로고    scopus 로고
    • A met a-analysis and systematic review of the efficacy and safety of anticoagulants as cancer treatment: Impact on survival and bleeding complications
    • Kuderer N M, K horana A A, Lyman GH, Francis CW. A met a-analysis and systematic review of the efficacy and safety of anticoagulants as cancer treatment: impact on survival and bleeding complications. Cancer 2007; 110: 1149-1161.
    • (2007) Cancer , vol.110 , pp. 1149-1161
    • Kuderer, N.M.1    Khorana, A.A.2    Lyman, G.H.3    Francis, C.W.4
  • 104
    • 33744823500 scopus 로고    scopus 로고
    • Low-molecular-weight heparin in patients with advanced cancer: A phase 3 clinical trial
    • Sideras K, Schaefer PL, Okuno SH, et al. Low-molecular-weight heparin in patients with advanced cancer: a phase 3 clinical trial. Mayo Clin Proc 2006;81:758-767.
    • (2006) Mayo Clin Proc , vol.81 , pp. 758-767
    • Sideras, K.1    Schaefer, P.L.2    Okuno, S.H.3


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