Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate

Molecular Cell

Volumn 54, Issue 6, 2014, Pages 905-919

  Gelato, Kathy A ^a   Tauber, Maria ^a   Ong, Michelle S ^b   Winter, Stefan ^a   Hiragami Hamada, Kyoko ^a   Sindlinger, Julia ^c   Lemak, Alexander ^d   Bultsma, Yvette ^e   Houliston, Scott ^b,d   Schwarzer, Dirk ^c   Divecha, Nullin ^e   Arrowsmith, Cheryl H ^b,d   Fischle, Wolfgang ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d PRINCESS MARGARET HOSPITAL   (Canada)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; PHOSPHATIDYLINOSITOL; POLYPHOSPHOINOSITIDE; PROTEIN UHRF1; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ALLOSTERIC REGULATION; BINDING SITES; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE, TUMOR; DNA METHYLATION; HELA CELLS; HETEROCHROMATIN; HISTONES; HUMANS; MOLECULAR DOCKING SIMULATION; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84902652431     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.04.004     Document Type: Article

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