메뉴 건너뛰기




Volumn 8, Issue JUN, 2014, Pages

Structure,function,and plasticity of GABA transporters

Author keywords

GABA; GABA transporters; GAT1; GAT3; SLC6; Synaptic plasticity; Synaptic transmission; Uptake

Indexed keywords

1 (4, 4 DIPHENYL 3 BUTENYL) NIPECOTIC ACID; 4 AMINOBUTYRIC ACID CARRIER; ABC TRANSPORTER A1; ABC TRANSPORTER A12; ABC TRANSPORTER A13; ABC TRANSPORTER A6; ABC TRANSPORTER A8; AMINO ACID RECEPTOR AFFECTING AGENT; CALCINEURIN; CALCIUM ION; CREATINE; CREATINE TRANSPORTER; EZRIN; GABA TRANSPORTER 1; GABA TRANSPORTER 2; GABA TRANSPORTER 3; GAMMA AMINOBUTYRIC ACID TRANSPORTER; MEMBRANE ASSOCIATED GUANYLATE CYCLASE KINASE; MESSENGER RNA; MONOAMINE; PDZ PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; SODIUM ION; SOLUTE CARRIER 6; TAURINE TRANSPORTER; TIAGABINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84902594501     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2014.00161     Document Type: Article
Times cited : (180)

References (131)
  • 1
    • 69249136609 scopus 로고    scopus 로고
    • Structure and function of Na(+)-symporters with inverted repeats
    • doi: 10.1016/j.sbi.2009.06.002
    • Abramson, J., and Wright, E. M. (2009). Structure and function of Na(+)-symporters with inverted repeats. Curr. Opin. Struct. Biol. 19, 425-432. doi: 10.1016/j.sbi.2009.06.002
    • (2009) Curr. Opin. Struct. Biol , vol.19 , pp. 425-432
    • Abramson, J.1    Wright, E.M.2
  • 2
    • 77955508204 scopus 로고    scopus 로고
    • Oscillations and filtering networks support flexible routing of information
    • doi: 10.1016/j.neuron.2010.06.019
    • Akam, T., and Kullmann, D. M. (2010). Oscillations and filtering networks support flexible routing of information. Neuron 67, 308-320. doi: 10.1016/j.neuron.2010.06.019
    • (2010) Neuron , vol.67 , pp. 308-320
    • Akam, T.1    Kullmann, D.M.2
  • 3
    • 0020001034 scopus 로고
    • Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro
    • Alger, B. E., and Nicoll, R. A. (1982). Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro. J. Physiol. 328, 125-141.
    • (1982) J. Physiol , vol.328 , pp. 125-141
    • Alger, B.E.1    Nicoll, R.A.2
  • 4
    • 1942489741 scopus 로고    scopus 로고
    • Sequential release of GABA by exocytosis and reversed uptake leads to neuronal swelling in simulated ischemia of hippocampal slices
    • doi: 10.1523/JNEUROSCI.5539-03.2004
    • Allen, N. J., Rossi, D. J., and Attwell, D. (2004). Sequential release of GABA by exocytosis and reversed uptake leads to neuronal swelling in simulated ischemia of hippocampal slices. J. Neurosci. 24, 3837-3849. doi: 10.1523/JNEUROSCI.5539-03.2004
    • (2004) J. Neurosci , vol.24 , pp. 3837-3849
    • Allen, N.J.1    Rossi, D.J.2    Attwell, D.3
  • 5
    • 0038644891 scopus 로고    scopus 로고
    • Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters
    • doi: 10.1074/jbc.M206563200
    • Androutsellis-Theotokis, A., Goldberg, N. R., Ueda, K., Beppu, T., Beckman, M. L., Das, S., et al. (2003). Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters. J. Biol. Chem. 278, 12703-12709. doi: 10.1074/jbc.M206563200
    • (2003) J. Biol. Chem , vol.278 , pp. 12703-12709
    • Androutsellis-Theotokis, A.1    Goldberg, N.R.2    Ueda, K.3    Beppu, T.4    Beckman, M.L.5    Das, S.6
  • 6
    • 84862617680 scopus 로고    scopus 로고
    • Impact of synaptic neurotransmitter concentration time course on the kinetics and pharmacological modulation of inhibitory synaptic currents
    • doi: 10.3389/fncel.2011.00006
    • Barberis, A., Petrini, E. M., and Mozrzymas, J. W. (2011). Impact of synaptic neurotransmitter concentration time course on the kinetics and pharmacological modulation of inhibitory synaptic currents. Front. Cell. Neurosci. 5:6. doi: 10.3389/fncel.2011.00006
    • (2011) Front. Cell. Neurosci , vol.5 , Issue.6
    • Barberis, A.1    Petrini, E.M.2    Mozrzymas, J.W.3
  • 7
    • 0032529350 scopus 로고    scopus 로고
    • Protein kinase C regulates the interaction between a GABA transporter and syntaxin 1A
    • Beckman, M. L., Bernstein, E. M., and Quick, M. W. (1998). Protein kinase C regulates the interaction between a GABA transporter and syntaxin 1A. J. Neurosci. 18, 6103-6112.
    • (1998) J. Neurosci , vol.18 , pp. 6103-6112
    • Beckman, M.L.1    Bernstein, E.M.2    Quick, M.W.3
  • 8
    • 0033139923 scopus 로고    scopus 로고
    • Multiple G protein coupled receptors initiate protein kinase C redistribution of GABA transporters in hippocampal neurons
    • Beckman, M. L., Bernstein, E. M., and Quick, M. W. (1999). Multiple G protein coupled receptors initiate protein kinase C redistribution of GABA transporters in hippocampal neurons. J. Neurosci. 19, RC9.
    • (1999) J. Neurosci , vol.19
    • Beckman, M.L.1    Bernstein, E.M.2    Quick, M.W.3
  • 9
    • 78149482189 scopus 로고    scopus 로고
    • Astrocytes as gatekeepers of GABAB receptor function
    • doi: 10.1523/JNEUROSCI.3243-10.2010
    • Beenhakker, M. P., and Huguenard, J. R. (2010). Astrocytes as gatekeepers of GABAB receptor function. J. Neurosci. 30, 15262-15276. doi: 10.1523/JNEUROSCI.3243-10.2010
    • (2010) J. Neurosci , vol.30 , pp. 15262-15276
    • Beenhakker, M.P.1    Huguenard, J.R.2
  • 10
    • 0024430857 scopus 로고
    • Giant synaptic potentials in immature rat CA3 hippocampal neurones
    • Ben-Ari, Y., Cherubini, E., Corradetti, R., and Gaiarsa, J. L. (1989). Giant synaptic potentials in immature rat CA3 hippocampal neurones. J. Physiol. 416, 303-325.
    • (1989) J. Physiol , vol.416 , pp. 303-325
    • Ben-Ari, Y.1    Cherubini, E.2    Corradetti, R.3    Gaiarsa, J.L.4
  • 11
    • 0029056356 scopus 로고
    • GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro
    • Berninger, B., Marty, S., Zafra, F., Da Penha Berzaghi, M., Thoenen, H., and Lindholm, D. (1995). GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development 121, 2327-2335.
    • (1995) Development , vol.121 , pp. 2327-2335
    • Berninger, B.1    Marty, S.2    Zafra, F.3    Da Penha, B.M.4    Thoenen, H.5    Lindholm, D.6
  • 12
    • 23244455942 scopus 로고    scopus 로고
    • Rapid substrate-induced charge movements of the GABA transporter GAT1
    • doi: 10.1529/bio-, physj.105.061002
    • Bicho, A., and Grewer, C. (2005). Rapid substrate-induced charge movements of the GABA transporter GAT1. Biophys. J. 89, 211-231. doi: 10.1529/bio-physj.105.061002
    • (2005) Biophys. J , vol.89 , pp. 211-231
    • Bicho, A.1    Grewer, C.2
  • 13
    • 0030921440 scopus 로고    scopus 로고
    • Tyrosine 140 of the gamma-aminobutyric acid transporter GAT-1 plays a critical role in neurotransmitter recognition
    • doi: 10.1074/jbc.272.26.16096
    • Bismuth, Y., Kavanaugh, M. P., and Kanner, B. I. (1997). Tyrosine 140 of the gamma-aminobutyric acid transporter GAT-1 plays a critical role in neurotransmitter recognition. J. Biol. Chem. 272,16096-16102. doi: 10.1074/jbc.272.26.16096
    • (1997) J. Biol. Chem , vol.272 , pp. 16096-16102
    • Bismuth, Y.1    Kavanaugh, M.P.2    Kanner, B.I.3
  • 14
    • 0030272426 scopus 로고    scopus 로고
    • GABA transporter heterogeneity: Pharmacology and cellular localization
    • doi: 10.1016/0197-0186(95) 00158-1
    • Borden, L. A. (1996). GABA transporter heterogeneity: pharmacology and cellular localization. Neurochem. Int. 29, 335-356. doi: 10.1016/0197-0186(95) 00158-1
    • (1996) Neurochem. Int , vol.29 , pp. 335-356
    • Borden, L.A.1
  • 15
    • 0030476450 scopus 로고    scopus 로고
    • Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors
    • Brickley, S. G., Cull-Candy, S. G., and Farrant, M. (1996). Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors. J. Physiol. 497(Pt 3), 753-759.
    • (1996) J. Physiol , vol.497 , Issue.PART 3 , pp. 753-759
    • Brickley, S.G.1    Cull-Candy, S.G.2    Farrant, M.3
  • 16
    • 84865425436 scopus 로고    scopus 로고
    • The solute carrier 6 family of transporters
    • doi: 10.1111/j.1476-5381.2012.01975.x
    • Broer, S., and Gether, U. (2012). The solute carrier 6 family of transporters. Br. J. Pharmacol. 167, 256-278. doi: 10.1111/j.1476-5381.2012.01975.x
    • (2012) Br. J. Pharmacol , vol.167 , pp. 256-278
    • Broer, S.1    Gether, U.2
  • 17
    • 0018819662 scopus 로고
    • Influence of cellular transport on the interaction of amino acids with gamma-aminobutyric acid (GABA) receptors in the isolated olfactory cortex of the guinea-pig
    • doi: 10.1111/j.1476-5381.1980.tb10414.x
    • Brown, D. A., Collins, G. G., and Galvan, M. (1980). Influence of cellular transport on the interaction of amino acids with gamma-aminobutyric acid (GABA) receptors in the isolated olfactory cortex of the guinea-pig. Br. J. Pharmacol. 68, 251-262. doi: 10.1111/j.1476-5381.1980.tb10414.x
    • (1980) Br. J. Pharmacol , vol.68 , pp. 251-262
    • Brown, D.A.1    Collins, G.G.2    Galvan, M.3
  • 18
    • 0017363225 scopus 로고
    • Influence of neuroglial transport on the action of gamma-aminobutyric acid on mammalian ganglion cells
    • doi: 10.1111/j.1476-5381.1977.tb07502.x
    • Brown, D. A., and Galvan, M. (1977). Influence of neuroglial transport on the action of gamma-aminobutyric acid on mammalian ganglion cells. Br. J. Pharmacol. 59, 373-378. doi: 10.1111/j.1476-5381.1977.tb07502.x
    • (1977) Br. J. Pharmacol , vol.59 , pp. 373-378
    • Brown, D.A.1    Galvan, M.2
  • 19
    • 0029671435 scopus 로고    scopus 로고
    • Channel behavior in a gamma-aminobutyrate transporter
    • doi: 10.1073/pnas.93.2.723
    • Cammack, J. N., and Schwartz, E. A. (1996). Channel behavior in a gamma-aminobutyrate transporter. Proc. Natl. Acad. Sci. U.S.A. 93, 723-727. doi: 10.1073/pnas.93.2.723
    • (1996) Proc. Natl. Acad. Sci. U.S.A , vol.93 , pp. 723-727
    • Cammack, J.N.1    Schwartz, E.A.2
  • 20
    • 79551611534 scopus 로고    scopus 로고
    • GABA A,slow: Causes and consequences
    • doi: 10.1016/j.tins.2010.10.005
    • Capogna, M., and Pearce, R. A. (2011). GABA A,slow: causes and consequences. Trends Neurosci. 34, 101-112. doi: 10.1016/j.tins.2010.10.005
    • (2011) Trends Neurosci , vol.34 , pp. 101-112
    • Capogna, M.1    Pearce, R.A.2
  • 21
    • 12144288505 scopus 로고    scopus 로고
    • Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors
    • doi: 10.1073/pnas.0307231101
    • Caraiscos, V. B., Elliott, E. M., You-Ten, K. E., Cheng, V. Y., Belelli, D., Newell, J. G., et al. (2004). Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors. Proc. Natl. Acad. Sci. U.S.A. 101, 3662-3667. doi: 10.1073/pnas.0307231101
    • (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 3662-3667
    • Caraiscos, V.B.1    Elliott, E.M.2    You-Ten, K.E.3    Cheng, V.Y.4    Belelli, D.5    Newell, J.G.6
  • 22
    • 4744367001 scopus 로고    scopus 로고
    • Tonic excitation and inhibition of neurons: Ambient transmitter sources and computational consequences
    • doi: 10.1016/j.pbiomolbio.2004.06.001
    • Cavelier, P., Hamann, M., Rossi, D., Mobbs, P., and Attwell, D. (2005). Tonic excitation and inhibition of neurons: ambient transmitter sources and computational consequences. Prog. Biophys. Mol. Biol. 87, 3-16. doi: 10.1016/j.pbiomolbio.2004.06.001
    • (2005) Prog. Biophys. Mol. Biol , vol.87 , pp. 3-16
    • Cavelier, P.1    Hamann, M.2    Rossi, D.3    Mobbs, P.4    Attwell, D.5
  • 23
    • 1942435220 scopus 로고    scopus 로고
    • Integration of quanta in cerebellar granule cells during sensory processing
    • doi: 10.1038/nature02442
    • Chadderton, P., Margrie, T. W., and Hausser, M. (2004). Integration of quanta in cerebellar granule cells during sensory processing. Nature 428, 856-860. doi: 10.1038/nature02442
    • (2004) Nature , vol.428 , pp. 856-860
    • Chadderton, P.1    Margrie, T.W.2    Hausser, M.3
  • 24
    • 84871720372 scopus 로고    scopus 로고
    • Neurogliaform cells dynamically regulate somatosensory integration via synapse-specific modulation
    • doi: 10.1038/nn.3284
    • Chittajallu, R., Pelkey, K. A., and Mcbain, C. J. (2013). Neurogliaform cells dynamically regulate somatosensory integration via synapse-specific modulation. Nat. Neurosci. 16, 13-15. doi: 10.1038/nn.3284
    • (2013) Nat. Neurosci , vol.16 , pp. 13-15
    • Chittajallu, R.1    Pelkey, K.A.2    McBain, C.J.3
  • 25
    • 0036897386 scopus 로고    scopus 로고
    • Number, density, and surface/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions
    • Chiu, C. S., Jensen, K., Sokolova, I., Wang, D., Li, M., Deshpande, P., et al. (2002). Number, density, and surface/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions. J. Neurosci. 22, 10251-10266.
    • (2002) J. Neurosci , vol.22 , pp. 10251-10266
    • Chiu, C.S.1    Jensen, K.2    Sokolova, I.3    Wang, D.4    Li, M.5    Deshpande, P.6
  • 26
    • 84886954019 scopus 로고    scopus 로고
    • Single-molecule fluorescence probes dynamics of barrier crossing
    • doi: 10.1038/nature 12649
    • Chung, H. S., and Eaton, W. A. (2013). Single-molecule fluorescence probes dynamics of barrier crossing. Nature 502, 685-688. doi: 10.1038/nature 12649
    • (2013) Nature , vol.502 , pp. 685-688
    • Chung, H.S.1    Eaton, W.A.2
  • 27
    • 17844394176 scopus 로고    scopus 로고
    • Zinc inhibition of gamma-aminobutyric acid transporter 4 (GAT4) reveals a link between excitatory and inhibitory neurotransmission
    • doi: 10.1073/pnas.0501431102
    • Cohen-Kfir, E., Lee, W., Eskandari, S., and Nelson, N. (2005). Zinc inhibition of gamma-aminobutyric acid transporter 4 (GAT4) reveals a link between excitatory and inhibitory neurotransmission. Proc. Natl. Acad. Sci. U.S.A. 102, 6154-6159. doi: 10.1073/pnas.0501431102
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 6154-6159
    • Cohen-Kfir, E.1    Lee, W.2    Eskandari, S.3    Nelson, N.4
  • 28
    • 3042649213 scopus 로고    scopus 로고
    • GABA transporters in the mammalian cerebral cortex: Localization, development and pathological implications
    • doi: 10.1016/j.brainresrev.2004.03.003
    • Conti, F., Minelli, A., and Melone, M. (2004). GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications. Brain Res. Brain Res. Rev. 45, 196-212. doi: 10.1016/j.brainresrev.2004.03.003
    • (2004) Brain Res. Brain Res. Rev , vol.45 , pp. 196-212
    • Conti, F.1    Minelli, A.2    Melone, M.3
  • 29
    • 0028334675 scopus 로고
    • Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter
    • Corey, J. L., Davidson, N., Lester, H. A., Brecha, N., and Quick, M. W. (1994). Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter. J. Biol. Chem. 269, 14759-14767.
    • (1994) J. Biol. Chem , vol.269 , pp. 14759-14767
    • Corey, J.L.1    Davidson, N.2    Lester, H.A.3    Brecha, N.4    Quick, M.W.5
  • 30
    • 0017124981 scopus 로고
    • The in vivo inactivation of GABA and other inhibitory amino acids in the cat nervous system
    • doi: 10.1007/BF00241731
    • Curtis, D. R., Game, C. J., and Lodge, D. (1976). The in vivo inactivation of GABA and other inhibitory amino acids in the cat nervous system. Exp. Brain Res. 25, 413-428. doi: 10.1007/BF00241731
    • (1976) Exp. Brain Res , vol.25 , pp. 413-428
    • Curtis, D.R.1    Game, C.J.2    Lodge, D.3
  • 31
    • 0032484493 scopus 로고    scopus 로고
    • Immunoreactivity for the GABA transporter-1 and GABA transporter-3 is restricted to astrocytes in the rat thalamus. A light and electron-microscopic immunolocalization
    • doi: 10.1016/S0306-4522(97)00414-4
    • De Biasi, S., Vitellaro-Zuccarello, L., and Brecha, N. C. (1998). Immunoreactivity for the GABA transporter-1 and GABA transporter-3 is restricted to astrocytes in the rat thalamus. A light and electron-microscopic immunolocalization. Neuroscience 83, 815-828. doi: 10.1016/S0306-4522(97)00414-4
    • (1998) Neuroscience , vol.83 , pp. 815-828
    • de Biasi, S.1    Vitellaro-Zuccarello, L.2    Brecha, N.C.3
  • 32
    • 0022270903 scopus 로고
    • Gamma-aminobutyric acid uptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice
    • Dingledine, R., and Korn, S. J. (1985). Gamma-aminobutyric acid uptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice. J. Physiol. 366, 387-409.
    • (1985) J. Physiol , vol.366 , pp. 387-409
    • Dingledine, R.1    Korn, S.J.2
  • 33
    • 0030463015 scopus 로고    scopus 로고
    • Different mechanisms regulate IPSC kinetics in early postnatal and juvenile hippocampal granule cells
    • Draguhn, A., and Heinemann, U. (1996). Different mechanisms regulate IPSC kinetics in early postnatal and juvenile hippocampal granule cells. J. Neurophysiol. 76, 3983-3993.
    • (1996) J. Neurophysiol , vol.76 , pp. 3983-3993
    • Draguhn, A.1    Heinemann, U.2
  • 34
    • 84864832603 scopus 로고    scopus 로고
    • Tonic inhibition enhances fidelity of sensory information transmission in the cerebellar cortex
    • doi: 10.1523/JNEUROSCI.0460-12.2012
    • Duguid, I., Branco, T., London, M., Chadderton, P., and Hausser, M. (2012). Tonic inhibition enhances fidelity of sensory information transmission in the cerebellar cortex. J. Neurosci. 32, 11132-11143. doi: 10.1523/JNEUROSCI.0460-12.2012
    • (2012) J. Neurosci , vol.32 , pp. 11132-11143
    • Duguid, I.1    Branco, T.2    London, M.3    Chadderton, P.4    Hausser, M.5
  • 35
    • 0029150964 scopus 로고
    • Localization of messenger RNAs encoding three GABA transporters in rat brain: An in situ hybridization study. Brain Res
    • doi: 10.1016/0169-328X(95)00101-W
    • Durkin, M. M., Smith, K. E., Borden, L. A., Weinshank, R. L., Branchek, T. A., and Gustafson, E. L. (1995). Localization of messenger RNAs encoding three GABA transporters in rat brain: an in situ hybridization study. Brain Res. Mol. Brain Res. 33, 7-21. doi: 10.1016/0169-328X(95)00101-W
    • (1995) Mol. Brain Res , vol.33 , pp. 7-21
    • Durkin, M.M.1    Smith, K.E.2    Borden, L.A.3    Weinshank, R.L.4    Branchek, T.A.5    Gustafson, E.L.6
  • 36
    • 0032869610 scopus 로고    scopus 로고
    • Inhibition of uptake, steadystate currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs
    • doi: 10.1038/sj.bjp.0702794
    • Eckstein-Ludwig, U., Fei, J., and Schwarz, W. (1999). Inhibition of uptake, steadystate currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs. Br. J. Pharmacol. 128, 92-102. doi: 10.1038/sj.bjp.0702794
    • (1999) Br. J. Pharmacol , vol.128 , pp. 92-102
    • Eckstein-Ludwig, U.1    Fei, J.2    Schwarz, W.3
  • 37
    • 0032211438 scopus 로고    scopus 로고
    • Laminar difference in GABA uptake and GAT-1 expression in rat CA1
    • doi: 10.1111/j.1469-7793.1998.643bd.x
    • Engel, D., Schmitz, D., Gloveli, T., Frahm, C., Heinemann, U., and Draguhn, A. (1998). Laminar difference in GABA uptake and GAT-1 expression in rat CA1. J. Physiol. 512(Pt 3), 643-649. doi: 10.1111/j.1469-7793.1998.643bd.x
    • (1998) J. Physiol , vol.512 , Issue.PART 3 , pp. 643-649
    • Engel, D.1    Schmitz, D.2    Gloveli, T.3    Frahm, C.4    Heinemann, U.5    Draguhn, A.6
  • 38
    • 0025132860 scopus 로고
    • Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family
    • doi: 10.1016/0896-6273(90)90090-3
    • Ernfors, P., Wetmore, C., Olson, L., and Persson, H. (1990). Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron 5, 511-526. doi: 10.1016/0896-6273(90)90090-3
    • (1990) Neuron , vol.5 , pp. 511-526
    • Ernfors, P.1    Wetmore, C.2    Olson, L.3    Persson, H.4
  • 39
    • 34247350910 scopus 로고    scopus 로고
    • Oligomerization of neurotransmitter transporters: A ticket from the endoplasmic reticulum to the plasma membrane
    • doi: 10.1007/3-540-29784-7_12
    • Farhan, H., Freissmuth, M., and Sitte, H. H. (2006). Oligomerization of neurotransmitter transporters: a ticket from the endoplasmic reticulum to the plasma membrane. Handb. Exp. Pharmacol. 175, 233-249. doi: 10.1007/3-540-29784-7_12
    • (2006) Handb. Exp. Pharmacol , vol.175 , pp. 233-249
    • Farhan, H.1    Freissmuth, M.2    Sitte, H.H.3
  • 40
    • 14844323722 scopus 로고    scopus 로고
    • Variations on an inhibitory theme: Phasic and tonic activation of GABA(A) receptors
    • doi: 10.1038/nrn1625
    • Farrant, M., and Nusser, Z. (2005). Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors. Nat. Rev. Neurosci. 6, 215-229. doi: 10.1038/nrn1625
    • (2005) Nat. Rev. Neurosci , vol.6 , pp. 215-229
    • Farrant, M.1    Nusser, Z.2
  • 41
    • 0030337503 scopus 로고    scopus 로고
    • Interneurons of the hippocampus
    • Freund, T. F., and Buzsaki, G. (1996). Interneurons of the hippocampus. Hippocampus 6, 347-470.
    • (1996) Hippocampus , vol.6 , pp. 347-470
    • Freund, T.F.1    Buzsaki, G.2
  • 42
    • 33745555489 scopus 로고    scopus 로고
    • Neurotransmitter transporters: Molecular function of important drug targets. Trends Pharmacol
    • doi: 10.1016/j.tips.2006.05.003
    • Gether, U., Andersen, P. H., Larsson, O. M., and Schousboe, A. (2006). Neurotransmitter transporters: molecular function of important drug targets. Trends Pharmacol. Sci. 27, 375-383. doi: 10.1016/j.tips.2006.05.003
    • (2006) Sci , vol.27 , pp. 375-383
    • Gether, U.1    Andersen, P.H.2    Larsson, O.M.3    Schousboe, A.4
  • 43
    • 0025728459 scopus 로고
    • Inhibition of high-affinity gamma-aminobutyric acid uptake in primary astrocyte cultures by phorbol esters and phospholipase C
    • Gomeza, J., Casado, M., Gimenez, C., and Aragon, C. (1991). Inhibition of high-affinity gamma-aminobutyric acid uptake in primary astrocyte cultures by phorbol esters and phospholipase C. Biochem. J. 275(Pt 2), 435-439.
    • (1991) Biochem. J , vol.275 , Issue.PART 2 , pp. 435-439
    • Gomeza, J.1    Casado, M.2    Gimenez, C.3    Aragon, C.4
  • 44
    • 37449000179 scopus 로고    scopus 로고
    • Turnover rate of the gamma-aminobutyric acid transporter GAT1
    • doi: 10.1007/s00232-007-9073-5
    • Gonzales, A. L., Lee, W., Spencer, S. R., Oropeza, R. A., Chapman, J. V., Ku, J. Y., et al. (2007). Turnover rate of the gamma-aminobutyric acid transporter GAT1. J. Membr. Biol. 220, 33-51. doi: 10.1007/s00232-007-9073-5
    • (2007) J. Membr. Biol , vol.220 , pp. 33-51
    • Gonzales, A.L.1    Lee, W.2    Spencer, S.R.3    Oropeza, R.A.4    Chapman, J.V.5    Ku, J.Y.6
  • 45
    • 0025048435 scopus 로고
    • Cloning and expression of a rat brain GABA transporter
    • doi: 10.1126/science.1975955
    • Guastella, J., Nelson, N., Nelson, H., Czyzyk, L., Keynan, S., Miedel, M. C., et al. (1990). Cloning and expression of a rat brain GABA transporter. Science 249, 1303-1306. doi: 10.1126/science.1975955
    • (1990) Science , vol.249 , pp. 1303-1306
    • Guastella, J.1    Nelson, N.2    Nelson, H.3    Czyzyk, L.4    Keynan, S.5    Miedel, M.C.6
  • 46
    • 0029830262 scopus 로고    scopus 로고
    • Pyramidal cell dendrites are the primary targets of calbindin D28k-immunoreactive interneurons in the hippocampus
    • Gulyas, A. I., and Freund, T. F. (1996). Pyramidal cell dendrites are the primary targets of calbindin D28k-immunoreactive interneurons in the hippocampus. Hippocampus 6, 525-534.
    • (1996) Hippocampus , vol.6 , pp. 525-534
    • Gulyas, A.I.1    Freund, T.F.2
  • 47
    • 0242478977 scopus 로고    scopus 로고
    • Cell type and synapse-specific variability in synaptic GABAA receptor occupancy
    • doi: 10.1046/j.1460-9568.2000.00964.x
    • Hajos, N., Nusser, Z., Rancz, E. A., Freund, T. F., and Mody, I. (2000). Cell type and synapse-specific variability in synaptic GABAA receptor occupancy. Eur. J. Neurosci. 12, 810-818. doi: 10.1046/j.1460-9568.2000.00964.x
    • (2000) Eur. J. Neurosci , vol.12 , pp. 810-818
    • Hajos, N.1    Nusser, Z.2    Rancz, E.A.3    Freund, T.F.4    Mody, I.5
  • 48
    • 5644277512 scopus 로고    scopus 로고
    • Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro
    • doi: 10.1523/JNEUROSCI.2113-04.2004
    • Hajos, N., Palhalmi, J., Mann, E. O., Nemeth, B., Paulsen, O., and Freund, T. F. (2004). Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro. J. Neurosci. 24, 9127-9137. doi: 10.1523/JNEUROSCI.2113-04.2004
    • (2004) J. Neurosci , vol.24 , pp. 9127-9137
    • Hajos, N.1    Palhalmi, J.2    Mann, E.O.3    Nemeth, B.4    Paulsen, O.5    Freund, T.F.6
  • 49
    • 0037075234 scopus 로고    scopus 로고
    • Tonic and spillover inhibition of granule cells control information flow through cerebellar cortex
    • doi: 10.1016/S0896-6273(02)00593-7
    • Hamann, M., Rossi, D. J., and Attwell, D. (2002). Tonic and spillover inhibition of granule cells control information flow through cerebellar cortex. Neuron 33, 625-633. doi: 10.1016/S0896-6273(02)00593-7
    • (2002) Neuron , vol.33 , pp. 625-633
    • Hamann, M.1    Rossi, D.J.2    Attwell, D.3
  • 50
    • 84860426170 scopus 로고    scopus 로고
    • Astrocytes convert network excitation to tonic inhibition of neurons
    • doi: 10.1186/1741-7007-10-26
    • Heja, L., Nyitrai, G., Kekesi, O., Dobolyi, A., Szabo, P., Fiath, R., et al. (2012). Astrocytes convert network excitation to tonic inhibition of neurons. BMC Biol. 10:26. doi: 10.1186/1741-7007-10-26
    • (2012) BMC Biol , vol.10 , pp. 26
    • Heja, L.1    Nyitrai, G.2    Kekesi, O.3    Dobolyi, A.4    Szabo, P.5    Fiath, R.6
  • 51
    • 0032885746 scopus 로고    scopus 로고
    • GAT1 (GABA:Na+:Cl-) cotransport function. Database reconstruction with an alternating access model
    • doi: 10.1085/jgp.114.3.459
    • Hilgemann, D. W., and Lu, C. C. (1999). GAT1 (GABA:Na+:Cl-) cotransport function. Database reconstruction with an alternating access model. J. Gen. Physiol. 114, 459-475. doi: 10.1085/jgp.114.3.459
    • (1999) J. Gen. Physiol , vol.114 , pp. 459-475
    • Hilgemann, D.W.1    Lu, C.C.2
  • 52
    • 0028076933 scopus 로고
    • Production of specific antibodies against GABA transporter subtypes (GAT1, GAT2, GAT3) and their application to immunocytochemistry
    • doi: 10.1016/0169-328X(94)90072-8
    • Ikegaki, N., Saito, N., Hashima, M., and Tanaka, C. (1994). Production of specific antibodies against GABA transporter subtypes (GAT1, GAT2, GAT3) and their application to immunocytochemistry. Brain Res. Mol. Brain Res. 26, 47-54. doi: 10.1016/0169-328X(94)90072-8
    • (1994) Brain Res. Mol. Brain Res , vol.26 , pp. 47-54
    • Ikegaki, N.1    Saito, N.2    Hashima, M.3    Tanaka, C.4
  • 53
    • 66049154783 scopus 로고    scopus 로고
    • Ezrin mediates tethering of the gamma-aminobutyric acid transporter GAT1 to actin filaments via a C-terminal PDZ-interacting domain
    • doi: 10.1016/j.bpj.2008.11.070
    • Imoukhuede, P. I., Moss, F. J., Michael, D. J., Chow, R. H., and Lester, H. A. (2009). Ezrin mediates tethering of the gamma-aminobutyric acid transporter GAT1 to actin filaments via a C-terminal PDZ-interacting domain. Biophys. J. 96, 2949-2960. doi: 10.1016/j.bpj.2008.11.070
    • (2009) Biophys. J , vol.96 , pp. 2949-2960
    • Imoukhuede, P.I.1    Moss, F.J.2    Michael, D.J.3    Chow, R.H.4    Lester, H.A.5
  • 54
    • 0027401230 scopus 로고
    • Local and diffuse synaptic actions of GABA in the hippocampus
    • doi: 10.1016/0896-6273(93)90308-E
    • Isaacson, J. S., Solis, J. M., and Nicoll, R. A. (1993). Local and diffuse synaptic actions of GABA in the hippocampus. Neuron 10, 165-175. doi: 10.1016/0896-6273(93)90308-E
    • (1993) Neuron , vol.10 , pp. 165-175
    • Isaacson, J.S.1    Solis, J.M.2    Nicoll, R.A.3
  • 55
    • 0014340748 scopus 로고
    • The uptake of [3H]GABA by slices of rat cerebral cortex
    • doi: 10.1111/j.1471-4159.1968.tb06831.x
    • Iversen, L. L., and Neal, M. J. (1968). The uptake of [3H]GABA by slices of rat cerebral cortex. J. Neurochem. 15, 1141-1149. doi: 10.1111/j.1471-4159.1968.tb06831.x
    • (1968) J. Neurochem , vol.15 , pp. 1141-1149
    • Iversen, L.L.1    Neal, M.J.2
  • 56
    • 0014029736 scopus 로고
    • Simple allosteric model for membrane pumps
    • doi: 10.1038/211969a0
    • Jardetzky, O. (1966). Simple allosteric model for membrane pumps. Nature 211, 969-970. doi: 10.1038/211969a0
    • (1966) Nature , vol.211 , pp. 969-970
    • Jardetzky, O.1
  • 57
    • 0026691182 scopus 로고
    • The rapid generation of mutation data matrices from protein sequences
    • Jones, D. T., Taylor, W. R., and Thornton, J. M. (1992). The rapid generation of mutation data matrices from protein sequences. Comput. Appl. Biosci. 8, 275-282.
    • (1992) Comput. Appl. Biosci , vol.8 , pp. 275-282
    • Jones, D.T.1    Taylor, W.R.2    Thornton, J.M.3
  • 58
    • 0018138165 scopus 로고
    • Active transport of gamma-aminobutyric acid by membrane vesicles isolated from rat brain
    • doi: 10.1021/bi00600a011
    • Kanner, B. I. (1978). Active transport of gamma-aminobutyric acid by membrane vesicles isolated from rat brain. Biochemistry 17, 1207-1211. doi: 10.1021/bi00600a011
    • (1978) Biochemistry , vol.17 , pp. 1207-1211
    • Kanner, B.I.1
  • 59
    • 0026595365 scopus 로고
    • Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes
    • Kavanaugh, M. P., Arriza, J. L., North, R. A., and Amara, S. G. (1992). Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes. J. Biol. Chem. 267, 22007-22009.
    • (1992) J. Biol. Chem , vol.267 , pp. 22007-22009
    • Kavanaugh, M.P.1    Arriza, J.L.2    North, R.A.3    Amara, S.G.4
  • 60
    • 84877800385 scopus 로고    scopus 로고
    • A functional role for both aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus
    • doi: 10.1113/jphysiol.2012.246298
    • Kersante, F., Rowley, S. C., Pavlov, I., Gutierrez-Mecinas, M., Semyanov, A., Reul, J. M., et al. (2013). A functional role for both aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus. J. Physiol. 591, 2429-2441. doi: 10.1113/jphysiol.2012.246298
    • (2013) J. Physiol , vol.591 , pp. 2429-2441
    • Kersante, F.1    Rowley, S.C.2    Pavlov, I.3    Gutierrez-Mecinas, M.4    Semyanov, A.5    Reul, J.M.6
  • 61
    • 46849083268 scopus 로고    scopus 로고
    • Neuronal diversity and temporal dynamics: The unity of hippocampal circuit operations
    • doi: 10.1126/science.1149381
    • Klausberger, T., and Somogyi, P. (2008). Neuronal diversity and temporal dynamics: the unity of hippocampal circuit operations. Science 321, 53-57. doi: 10.1126/science.1149381
    • (2008) Science , vol.321 , pp. 53-57
    • Klausberger, T.1    Somogyi, P.2
  • 62
    • 27844506567 scopus 로고    scopus 로고
    • Identification and selective inhibition of the channel mode of the neuronal GABA transporter 1
    • Krause, S., and Schwarz, W. (2005). Identification and selective inhibition of the channel mode of the neuronal GABA transporter 1. Mol. Pharmacol. 68, 1728-1735.
    • (2005) Mol. Pharmacol , vol.68 , pp. 1728-1735
    • Krause, S.1    Schwarz, W.2
  • 63
    • 84856225222 scopus 로고    scopus 로고
    • X-ray structures of LeuT in substrate free outward-open and apo inward-open states
    • doi: 10.1038/nature10737
    • Krishnamurthy, H., and Gouaux, E. (2012). X-ray structures of LeuT in substrate free outward-open and apo inward-open states. Nature 481, 469-474. doi: 10.1038/nature10737
    • (2012) Nature , vol.481 , pp. 469-474
    • Krishnamurthy, H.1    Gouaux, E.2
  • 64
    • 79960673062 scopus 로고    scopus 로고
    • SLC6 neurotransmitter transporters: Structure, function, and regulation
    • doi: 10.1124/pr.108.000869
    • Kristensen, A. S., Andersen, J., Jorgensen, T. N., Sorensen, L., Eriksen, J., Loland, C. J., et al. (2011). SLC6 neurotransmitter transporters: structure, function, and regulation. Pharmacol. Rev. 63, 585-640. doi: 10.1124/pr.108.000869
    • (2011) Pharmacol. Rev , vol.63 , pp. 585-640
    • Kristensen, A.S.1    Andersen, J.2    Jorgensen, T.N.3    Sorensen, L.4    Eriksen, J.5    Loland, C.J.6
  • 65
    • 79955769299 scopus 로고    scopus 로고
    • Dopamine transport by the serotonin transporter: A mechanistically distinct mode of substrate translocation
    • doi: 10.1523/JNEUROSCI.0576-11.2011
    • Larsen, M. B., Sonders, M. S., Mortensen, O. V., Larson, G. A., Zahniser, N. R., and Amara, S. G. (2011). Dopamine transport by the serotonin transporter: a mechanistically distinct mode of substrate translocation. J. Neurosci. 31, 6605-6615. doi: 10.1523/JNEUROSCI.0576-11.2011
    • (2011) J. Neurosci , vol.31 , pp. 6605-6615
    • Larsen, M.B.1    Sonders, M.S.2    Mortensen, O.V.3    Larson, G.A.4    Zahniser, N.R.5    Amara, S.G.6
  • 66
    • 0019327170 scopus 로고
    • Fluctuations of barrier structure in ionic channels
    • doi: 10.1016/0005-, 2736(80)90299-0
    • Lauger, P., Stephan, W., and Frehland, E. (1980). Fluctuations of barrier structure in ionic channels. Biochim. Biophys. Acta 602, 167-180. doi: 10.1016/0005-2736(80)90299-0
    • (1980) Biochim. Biophys. Acta , vol.602 , pp. 167-180
    • Lauger, P.1    Stephan, W.2    Frehland, E.3
  • 67
    • 0034604649 scopus 로고    scopus 로고
    • Functional regulation of gamma aminobutyric acid transporters by direct tyrosine phosphorylation
    • doi: 10.1074/jbc.M910283199
    • Law, R. M., Stafford, A., and Quick, M. W. (2000). Functional regulation of gamma aminobutyric acid transporters by direct tyrosine phosphorylation. J. Biol. Chem. 275, 23986-23991. doi: 10.1074/jbc.M910283199
    • (2000) J. Biol. Chem , vol.275 , pp. 23986-23991
    • Law, R.M.1    Stafford, A.2    Quick, M.W.3
  • 68
    • 0032450498 scopus 로고    scopus 로고
    • Effect of mutation of glycosylation sites on the Na+ dependence of steady-state and transient currents generated by the neuronal GABA transporter
    • doi: 10.1016/S0005-2736(98)00200-4
    • Liu, Y., Eckstein-Ludwig, U., Fei, J., and Schwarz, W. (1998). Effect of mutation of glycosylation sites on the Na+ dependence of steady-state and transient currents generated by the neuronal GABA transporter. Biochim. Biophys. Acta 1415, 246-254. doi: 10.1016/S0005-2736(98)00200-4
    • (1998) Biochim. Biophys. Acta , vol.1415 , pp. 246-254
    • Liu, Y.1    Eckstein-Ludwig, U.2    Fei, J.3    Schwarz, W.4
  • 69
    • 0034535336 scopus 로고    scopus 로고
    • Role of Clin electrogenic Na+-coupled cotransporters GAT1 and SGLT1
    • doi: 10.1074/jbc.M007241200
    • Loo, D. D., Eskandari, S., Boorer, K. J., Sarkar, H. K., and Wright, E. M. (2000). Role of Clin electrogenic Na+-coupled cotransporters GAT1 and SGLT1. J. Biol. Chem. 275, 37414-37422. doi: 10.1074/jbc.M007241200
    • (2000) J. Biol. Chem , vol.275 , pp. 37414-37422
    • Loo, D.D.1    Eskandari, S.2    Boorer, K.J.3    Sarkar, H.K.4    Wright, E.M.5
  • 70
    • 0032886824 scopus 로고    scopus 로고
    • GAT1 (GABA:Na+:Cl) cotransport function. Kinetic studies in giant Xenopus oocyte membrane patches
    • doi: 10.1085/jgp.114.3.445
    • Lu, C. C., and Hilgemann, D. W. (1999a). GAT1 (GABA:Na+:Cl) cotransport function. Kinetic studies in giant Xenopus oocyte membrane patches. J. Gen. Physiol. 114, 445-457. doi: 10.1085/jgp.114.3.445
    • (1999) J. Gen. Physiol , vol.114 , pp. 445-457
    • Lu, C.C.1    Hilgemann, D.W.2
  • 71
    • 0032888516 scopus 로고    scopus 로고
    • GAT1 (GABA:Na+:Cl) cotransport function. Steady state studies in giant Xenopus oocyte membrane patches
    • doi: 10.1085/jgp.114.3.429
    • Lu, C. C., and Hilgemann, D. W. (1999b). GAT1 (GABA:Na+:Cl) cotransport function. Steady state studies in giant Xenopus oocyte membrane patches. J. Gen. Physiol. 114, 429-444. doi: 10.1085/jgp.114.3.429
    • (1999) J. Gen. Physiol , vol.114 , pp. 429-444
    • Lu, C.C.1    Hilgemann, D.W.2
  • 72
    • 0026801112 scopus 로고
    • Neither amino nor carboxyl termini are required for function of the sodium and chloride-coupled gamma-aminobutyric acid transporter from rat brain
    • Mabjeesh, N. J., and Kanner, B. I. (1992). Neither amino nor carboxyl termini are required for function of the sodium and chloride-coupled gamma-aminobutyric acid transporter from rat brain. J. Biol. Chem. 267, 2563-2568.
    • (1992) J. Biol. Chem , vol.267 , pp. 2563-2568
    • Mabjeesh, N.J.1    Kanner, B.I.2
  • 73
    • 0037107410 scopus 로고    scopus 로고
    • Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1
    • doi: 10.1113/jphysiol.2002.022897
    • Macaulay, N., Zeuthen, T., and Gether, U. (2002). Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1. J. Physiol. 544, 447-458. doi: 10.1113/jphysiol.2002.022897
    • (2002) J. Physiol , vol.544 , pp. 447-458
    • Macaulay, N.1    Zeuthen, T.2    Gether, U.3
  • 74
    • 0027537292 scopus 로고
    • Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes
    • doi: 10.1016/0896-6273(93)90309-F
    • Mager, S., Naeve, J., Quick, M., Labarca, C., Davidson, N., and Lester, H. A. (1993). Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes. Neuron 10, 177-188. doi: 10.1016/0896-6273(93)90309-F
    • (1993) Neuron , vol.10 , pp. 177-188
    • Mager, S.1    Naeve, J.2    Quick, M.3    Labarca, C.4    Davidson, N.5    Lester, H.A.6
  • 75
    • 75549090021 scopus 로고    scopus 로고
    • Control of hippocampal gamma oscillation frequency by tonic inhibition and excitation of interneurons
    • doi: 10.1038/nn.2464
    • Mann, E. O., and Mody, I. (2010). Control of hippocampal gamma oscillation frequency by tonic inhibition and excitation of interneurons. Nat. Neurosci. 13, 205-212. doi: 10.1038/nn.2464
    • (2010) Nat. Neurosci , vol.13 , pp. 205-212
    • Mann, E.O.1    Mody, I.2
  • 76
    • 0029937711 scopus 로고    scopus 로고
    • GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor
    • doi: 10.1016/S0896-6273(00)80075-6
    • Marty, S., Berninger, B., Carroll, P., and Thoenen, H. (1996a). GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron 16, 565-570. doi: 10.1016/S0896-6273(00)80075-6
    • (1996) Neuron , vol.16 , pp. 565-570
    • Marty, S.1    Berninger, B.2    Carroll, P.3    Thoenen, H.4
  • 77
    • 0030033442 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures
    • Marty, S., Carroll, P., Cellerino, A., Castren, E., Staiger, V., Thoenen, H., et al. (1996b). Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. J. Neurosci. 16, 675-687.
    • (1996) J. Neurosci , vol.16 , pp. 675-687
    • Marty, S.1    Carroll, P.2    Cellerino, A.3    Castren, E.4    Staiger, V.5    Thoenen, H.6
  • 78
    • 3242772137 scopus 로고    scopus 로고
    • The GABA transporter GAT1 and the MAGUK protein Pals1: Interaction, uptake modulation, and coexpression in the brain
    • doi: 10.1016/j.mcn.2004.03.006
    • Mchugh, E. M., Zhu, W., Milgram, S., and Mager, S. (2004). The GABA transporter GAT1 and the MAGUK protein Pals1: interaction, uptake modulation, and coexpression in the brain. Mol. Cell. Neurosci. 26, 406-417. doi: 10.1016/j.mcn.2004.03.006
    • (2004) Mol. Cell. Neurosci , vol.26 , pp. 406-417
    • McHugh, E.M.1    Zhu, W.2    Milgram, S.3    Mager, S.4
  • 79
    • 21744432838 scopus 로고    scopus 로고
    • Neuronal localization of the GABA transporter GAT-3 in human cerebral cortex: A procedural artifact
    • doi: 10.1016/j.jchemneu.2005.04.002
    • Melone, M., Barbaresi, P., Fattorini, G., and Conti, F. (2005). Neuronal localization of the GABA transporter GAT-3 in human cerebral cortex: a procedural artifact? J. Chem. Neuroanat. 30, 45-54. doi: 10.1016/j.jchemneu.2005.04.002
    • (2005) J. Chem. Neuroanat , vol.30 , pp. 45-54
    • Melone, M.1    Barbaresi, P.2    Fattorini, G.3    Conti, F.4
  • 80
    • 15844430479 scopus 로고    scopus 로고
    • Differences between somatic and dendritic inhibition in the hippocampus
    • doi: 10.1016/S0896-6273(00)80101-4
    • Miles, R., Toth, K., Gulyas, A. I., Hajos, N., and Freund, T. F. (1996). Differences between somatic and dendritic inhibition in the hippocampus. Neuron 16, 815-823. doi: 10.1016/S0896-6273(00)80101-4
    • (1996) Neuron , vol.16 , pp. 815-823
    • Miles, R.1    Toth, K.2    Gulyas, A.I.3    Hajos, N.4    Freund, T.F.5
  • 81
    • 0028849688 scopus 로고
    • GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex
    • Minelli, A., Brecha, N. C., Karschin, C., Debiasi, S., and Conti, F. (1995). GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex. J. Neurosci. 15, 7734-7746.
    • (1995) J. Neurosci , vol.15 , pp. 7734-7746
    • Minelli, A.1    Brecha, N.C.2    Karschin, C.3    Debiasi, S.4    Conti, F.5
  • 82
    • 0029789256 scopus 로고    scopus 로고
    • GAT-3, a high-affinity GABA plasma membrane transporter, is localized to astrocytic processes, and it is not confined to the vicinity of GABAergic synapses in the cerebral cortex
    • Minelli, A., Debiasi, S., Brecha, N. C., Zuccarello, L. V., and Conti, F. (1996). GAT-3, a high-affinity GABA plasma membrane transporter, is localized to astrocytic processes, and it is not confined to the vicinity of GABAergic synapses in the cerebral cortex. J. Neurosci. 16, 6255-6264.
    • (1996) J. Neurosci , vol.16 , pp. 6255-6264
    • Minelli, A.1    Debiasi, S.2    Brecha, N.C.3    Zuccarello, L.V.4    Conti, F.5
  • 83
    • 0037904662 scopus 로고    scopus 로고
    • Shunting inhibition modulates neuronal gain during synaptic excitation
    • doi: 10.1016/S0896-, 6273(03)00200-9
    • Mitchell, S. J., and Silver, R. A. (2003). Shunting inhibition modulates neuronal gain during synaptic excitation. Neuron 38, 433-445. doi: 10.1016/S0896-6273(03)00200-9
    • (2003) Neuron , vol.38 , pp. 433-445
    • Mitchell, S.J.1    Silver, R.A.2
  • 84
    • 73149090594 scopus 로고    scopus 로고
    • GABA transporter function, oligomerization state, and anchoring: Correlates with subcellularly resolved FRET
    • doi: 10.1085/jgp.200910314
    • Moss, F. J., Imoukhuede, P. I., Scott, K., Hu, J., Jankowsky, J. L., Quick, M. W., et al. (2009). GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET. J. Gen. Physiol. 134, 489-521. doi: 10.1085/jgp.200910314
    • (2009) J. Gen. Physiol , vol.134 , pp. 489-521
    • Moss, F.J.1    Imoukhuede, P.I.2    Scott, K.3    Hu, J.4    Jankowsky, J.L.5    Quick, M.W.6
  • 85
    • 0031753789 scopus 로고    scopus 로고
    • The family of Na+/Cl neurotransmitter transporters
    • doi: 10.1046/j.1471-4159.1998.71051785.x
    • Nelson, N. (1998). The family of Na+/Cl neurotransmitter transporters. J. Neurochem. 71, 1785-1803. doi: 10.1046/j.1471-4159.1998.71051785.x
    • (1998) J. Neurochem , vol.71 , pp. 1785-1803
    • Nelson, N.1
  • 86
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • doi: 10.1038/334661a0
    • Nishizuka, Y. (1988). The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334, 661-665. doi: 10.1038/334661a0
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 87
    • 0036097970 scopus 로고    scopus 로고
    • Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells
    • Nusser, Z., and Mody, I. (2002). Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells. J. Neurophysiol. 87, 2624-2628.
    • (2002) J. Neurophysiol , vol.87 , pp. 2624-2628
    • Nusser, Z.1    Mody, I.2
  • 88
    • 70350686715 scopus 로고    scopus 로고
    • Regulation of cortical microcircuits by unitary GABA-mediated volume transmission
    • doi: 10.1038/nature08503
    • Olah, S., Fule, M., Komlosi, G., Varga, C., Baldi, R., Barzo, P., et al. (2009). Regulation of cortical microcircuits by unitary GABA-mediated volume transmission. Nature 461, 1278-1281. doi: 10.1038/nature08503
    • (2009) Nature , vol.461 , pp. 1278-1281
    • Olah, S.1    Fule, M.2    Komlosi, G.3    Varga, C.4    Baldi, R.5    Barzo, P.6
  • 89
    • 0034331246 scopus 로고    scopus 로고
    • Slow desensitization regulates the availability of synaptic GABA(A) receptors
    • Overstreet, L. S., Jones, M. V., and Westbrook, G. L. (2000). Slow desensitization regulates the availability of synaptic GABA(A) receptors. J. Neurosci. 20, 7914-7921.
    • (2000) J. Neurosci , vol.20 , pp. 7914-7921
    • Overstreet, L.S.1    Jones, M.V.2    Westbrook, G.L.3
  • 90
    • 0037388630 scopus 로고    scopus 로고
    • Synapse density regulates independence at unitary inhibitory synapses
    • Overstreet, L. S., and Westbrook, G. L. (2003). Synapse density regulates independence at unitary inhibitory synapses. J. Neurosci. 23, 2618-2626.
    • (2003) J. Neurosci , vol.23 , pp. 2618-2626
    • Overstreet, L.S.1    Westbrook, G.L.2
  • 91
    • 8844286139 scopus 로고    scopus 로고
    • Measuring and modeling the spatiotemporal profile of GABA at the synapse
    • M. W. Quick (New York, NY: Wiley-Liss)
    • Overstreet, L. S., Westbrook, G. L., and Jones, M. V. (2003). "Measuring and modeling the spatiotemporal profile of GABA at the synapse," in Transmembrane Transporters, ed M. W. Quick (New York, NY: Wiley-Liss), 259-276.
    • (2003) Transmembrane Transporters , pp. 259-276
    • Overstreet, L.S.1    Westbrook, G.L.2    Jones, M.V.3
  • 92
    • 0027532379 scopus 로고
    • Only one of the charged amino acids located in the transmembrane alpha-helices of the gamma aminobutyric acid transporter (subtype A) is essential for its activity
    • Pantanowitz, S., Bendahan, A., and Kanner, B. I. (1993). Only one of the charged amino acids located in the transmembrane alpha-helices of the gamma aminobutyric acid transporter (subtype A) is essential for its activity. J. Biol. Chem. 268, 3222-3225.
    • (1993) J. Biol. Chem , vol.268 , pp. 3222-3225
    • Pantanowitz, S.1    Bendahan, A.2    Kanner, B.I.3
  • 93
    • 0020479205 scopus 로고
    • Energetics of gamma aminobutyrate transport in rat brain synaptosomes
    • Pastuszko, A., Wilson, D. F., and Erecinska, M. (1982). Energetics of gamma aminobutyrate transport in rat brain synaptosomes. J. Biol. Chem. 257, 7514-7519.
    • (1982) J. Biol. Chem , vol.257 , pp. 7514-7519
    • Pastuszko, A.1    Wilson, D.F.2    Erecinska, M.3
  • 94
    • 0035839003 scopus 로고    scopus 로고
    • Enforcement of temporal fidelity in pyramidal cells by somatic feed-forward inhibition
    • doi: 10.1126/science.1060342
    • Pouille, F., and Scanziani, M. (2001). Enforcement of temporal fidelity in pyramidal cells by somatic feed-forward inhibition. Science 293, 1159-1163. doi: 10.1126/science.1060342
    • (2001) Science , vol.293 , pp. 1159-1163
    • Pouille, F.1    Scanziani, M.2
  • 95
    • 21244465483 scopus 로고    scopus 로고
    • Differential expression of the GABA transporters GAT-1 and GAT-3 in brains of rats, cats, monkeys and humans
    • doi: 10.1007/s00441-004-0928-0
    • Pow, D. V., Sullivan, R. K., Williams, S. M., Scott, H. L., Dodd, P. R., and Finkelstein, D. (2005). Differential expression of the GABA transporters GAT-1 and GAT-3 in brains of rats, cats, monkeys and humans. Cell Tissue Res. 320, 379-392. doi: 10.1007/s00441-004-0928-0
    • (2005) Cell Tissue Res , vol.320 , pp. 379-392
    • Pow, D.V.1    Sullivan, R.K.2    Williams, S.M.3    Scott, H.L.4    Dodd, P.R.5    Finkelstein, D.6
  • 96
    • 0023002440 scopus 로고
    • Purification and identification of the functional sodium and chloride-coupled gamma-aminobutyric acid transport glycoprotein from rat brain
    • Radian, R., Bendahan, A., and Kanner, B. I. (1986). Purification and identification of the functional sodium and chloride-coupled gamma-aminobutyric acid transport glycoprotein from rat brain. J. Biol. Chem. 261, 15437-15441.
    • (1986) J. Biol. Chem , vol.261 , pp. 15437-15441
    • Radian, R.1    Bendahan, A.2    Kanner, B.I.3
  • 97
    • 0020575661 scopus 로고
    • Stoichiometry of sodium and chloride-coupled gamma-aminobutyric acid transport by synaptic plasma membrane vesicles isolated from rat brain
    • doi: 10.1021/bi00274a038
    • Radian, R., and Kanner, B. I. (1983). Stoichiometry of sodium and chloride-coupled gamma-aminobutyric acid transport by synaptic plasma membrane vesicles isolated from rat brain. Biochemistry 22, 1236-1241. doi: 10.1021/bi00274a038
    • (1983) Biochemistry , vol.22 , pp. 1236-1241
    • Radian, R.1    Kanner, B.I.2
  • 98
    • 0022178608 scopus 로고
    • Reconstitution and purification of the sodium and chloride-coupled gamma-aminobutyric acid transporter from rat brain
    • Radian, R., and Kanner, B. I. (1985). Reconstitution and purification of the sodium and chloride-coupled gamma-aminobutyric acid transporter from rat brain. J. Biol. Chem. 260, 11859-11865.
    • (1985) J. Biol. Chem , vol.260 , pp. 11859-11865
    • Radian, R.1    Kanner, B.I.2
  • 99
    • 0025060943 scopus 로고
    • The effect of two lipophilic gamma-aminobutyric acid uptake blockers in CA1 of the rat hippocampal slice
    • doi: 10.1111/j.1476-, 5381.1990.tb14661.x
    • Rekling, J. C., Jahnsen, H., and Mosfeldt Laursen, A. (1990). The effect of two lipophilic gamma-aminobutyric acid uptake blockers in CA1 of the rat hippocampal slice. Br. J. Pharmacol. 99, 103-106. doi: 10.1111/j.1476-5381.1990.tb14661.x
    • (1990) Br. J. Pharmacol , vol.99 , pp. 103-106
    • Rekling, J.C.1    Jahnsen, H.2    Mosfeldt, L.A.3
  • 100
    • 0029880132 scopus 로고    scopus 로고
    • GABA plasma membrane transporters, GAT-1 and GAT-3, display different distributions in the rat hippocampus
    • Ribak, C. E., Tong, W. M., and Brecha, N. C. (1996). GABA plasma membrane transporters, GAT-1 and GAT-3, display different distributions in the rat hippocampus. J. Comp. Neurol. 367, 595-606.
    • (1996) J. Comp. Neurol , vol.367 , pp. 595-606
    • Ribak, C.E.1    Tong, W.M.2    Brecha, N.C.3
  • 101
    • 0030040994 scopus 로고    scopus 로고
    • Sodium-dependent GABA-induced currents in GAT1-transfected HeLa cells
    • Risso, S., Defelice, L. J., and Blakely, R. D. (1996). Sodium-dependent GABA-induced currents in GAT1-transfected HeLa cells. J. Physiol. 490(Pt 3), 691-702.
    • (1996) J. Physiol , vol.490 , Issue.PART 3 , pp. 691-702
    • Risso, S.1    Defelice, L.J.2    Blakely, R.D.3
  • 102
    • 0026447816 scopus 로고
    • Comparison of the effect of the GABA uptake blockers, tiagabine and nipecotic acid, on inhibitory synaptic efficacy in hippocampal CA1 neurones
    • doi: 10.1016/0304-3940(92)90060-K
    • Roepstorff, A., and Lambert, J. D. (1992). Comparison of the effect of the GABA uptake blockers, tiagabine and nipecotic acid, on inhibitory synaptic efficacy in hippocampal CA1 neurones. Neurosci. Lett. 146, 131-134. doi: 10.1016/0304-3940(92)90060-K
    • (1992) Neurosci. Lett , vol.146 , pp. 131-134
    • Roepstorff, A.1    Lambert, J.D.2
  • 103
    • 0032055975 scopus 로고    scopus 로고
    • Spillover-mediated transmission at inhibitory synapses promoted by high affinity alpha6 subunit GABA(A) receptors and glomerular geometry
    • doi: 10.1016/S0896-6273(00) 81016-8
    • Rossi, D. J., and Hamann, M. (1998). Spillover-mediated transmission at inhibitory synapses promoted by high affinity alpha6 subunit GABA(A) receptors and glomerular geometry. Neuron 20, 783-795. doi: 10.1016/S0896-6273(00) 81016-8
    • (1998) Neuron , vol.20 , pp. 783-795
    • Rossi, D.J.1    Hamann, M.2
  • 104
    • 84900993073 scopus 로고    scopus 로고
    • Phasic, nonsynaptic GABA-a receptor-mediated inhibition entrains thalamocortical oscillations
    • doi: 10.1523/JNEUROSCI.4386-13.2014
    • Rovo, Z., Matyas, F., Bartho, P., Slezia, A., Lecci, S., Pellegrini, C., et al. (2014). Phasic, nonsynaptic GABA-a receptor-mediated inhibition entrains thalamocortical oscillations. J. Neurosci. 34, 7137-7147. doi: 10.1523/JNEUROSCI.4386-13.2014
    • (2014) J. Neurosci , vol.34 , pp. 7137-7147
    • Rovo, Z.1    Matyas, F.2    Bartho, P.3    Slezia, A.4    Lecci, S.5    Pellegrini, C.6
  • 105
    • 2442693929 scopus 로고    scopus 로고
    • The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway
    • doi: 10.1074/jbc.M304433200
    • Ryan, R. M., Mitrovic, A. D., and Vandenberg, R. J. (2004). The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway. J. Biol. Chem. 279, 20742-20751. doi: 10.1074/jbc.M304433200
    • (2004) J. Biol. Chem , vol.279 , pp. 20742-20751
    • Ryan, R.M.1    Mitrovic, A.D.2    Vandenberg, R.J.3
  • 106
    • 33645243793 scopus 로고    scopus 로고
    • Contributions of the GABAA receptor alpha6 subunit to phasic and tonic inhibition revealed by a naturally occurring polymorphism in the alpha6 gene
    • doi: 10.1523/JNEUROSCI.4799-05.2006
    • Santhakumar, V., Hanchar, H. J., Wallner, M., Olsen, R. W., and Otis, T. S. (2006). Contributions of the GABAA receptor alpha6 subunit to phasic and tonic inhibition revealed by a naturally occurring polymorphism in the alpha6 gene. J. Neurosci. 26, 3357-3364. doi: 10.1523/JNEUROSCI.4799-05.2006
    • (2006) J. Neurosci , vol.26 , pp. 3357-3364
    • Santhakumar, V.1    Hanchar, H.J.2    Wallner, M.3    Olsen, R.W.4    Otis, T.S.5
  • 108
    • 0035830829 scopus 로고    scopus 로고
    • Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells
    • doi: 10.1074/jbc.M007357200
    • Schmid, J. A., Scholze, P., Kudlacek, O., Freissmuth, M., Singer, E. A., and Sitte, H. H. (2001). Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells. J. Biol. Chem. 276, 3805-3810. doi: 10.1074/jbc.M007357200
    • (2001) J. Biol. Chem , vol.276 , pp. 3805-3810
    • Schmid, J.A.1    Scholze, P.2    Kudlacek, O.3    Freissmuth, M.4    Singer, E.A.5    Sitte, H.H.6
  • 109
    • 84886947977 scopus 로고    scopus 로고
    • Biophysics: Rough passage across a barrier
    • doi: 10.1038/nature12697
    • Schuler, B., and Clarke, J. (2013). Biophysics: rough passage across a barrier. Nature 502, 632-633. doi: 10.1038/nature12697
    • (2013) Nature , vol.502 , pp. 632-633
    • Schuler, B.1    Clarke, J.2
  • 110
    • 84901380376 scopus 로고    scopus 로고
    • Plasticity of GABA transporters: An unconventional route to shape inhibitory synaptic transmission
    • doi: 10.3389/fncel.2014.00128
    • Scimemi, A. (2014). Plasticity of GABA transporters: an unconventional route to shape inhibitory synaptic transmission. Front. Cell. Neurosci. 8:128. doi: 10.3389/fncel.2014.00128
    • (2014) Front. Cell. Neurosci , vol.8 , pp. 128
    • Scimemi, A.1
  • 111
    • 27344459317 scopus 로고    scopus 로고
    • Multiple and plastic receptors mediate tonic GABAA receptor currents in the hippocampus
    • doi: 10.1523/JNEUROSCI.2520-05.2005
    • Scimemi, A., Semyanov, A., Sperk, G., Kullmann, D. M., and Walker, M. C. (2005). Multiple and plastic receptors mediate tonic GABAA receptor currents in the hippocampus. J. Neurosci. 25, 10016-10024. doi: 10.1523/JNEUROSCI.2520-05.2005
    • (2005) J. Neurosci , vol.25 , pp. 10016-10024
    • Scimemi, A.1    Semyanov, A.2    Sperk, G.3    Kullmann, D.M.4    Walker, M.C.5
  • 112
    • 70949085269 scopus 로고    scopus 로고
    • Neuronal transporters regulate glutamate clearance, NMDA receptor activation, and synaptic plasticity in the hippocampus
    • doi: 10.1523/JNEUROSCI.4845-09.2009
    • Scimemi, A., Tian, H., and Diamond, J. S. (2009). Neuronal transporters regulate glutamate clearance, NMDA receptor activation, and synaptic plasticity in the hippocampus. J. Neurosci. 29, 14581-14595. doi: 10.1523/JNEUROSCI.4845-09.2009
    • (2009) J. Neurosci , vol.29 , pp. 14581-14595
    • Scimemi, A.1    Tian, H.2    Diamond, J.S.3
  • 113
    • 0037408550 scopus 로고    scopus 로고
    • GABA uptake regulates cortical excitability via cell type-specific tonic inhibition
    • doi: 10.1038/nn1043
    • Semyanov, A., Walker, M. C., and Kullmann, D. M. (2003). GABA uptake regulates cortical excitability via cell type-specific tonic inhibition. Nat. Neurosci. 6, 484-490. doi: 10.1038/nn1043
    • (2003) Nat. Neurosci , vol.6 , pp. 484-490
    • Semyanov, A.1    Walker, M.C.2    Kullmann, D.M.3
  • 114
    • 84874541649 scopus 로고    scopus 로고
    • Different transporter systems regulate extracellular GABA from vesicular and non-vesicular sources
    • doi: 10.3389/fncel.2013.00023
    • Song, I., Volynski, K., Brenner, T., Ushkaryov, Y., Walker, M., and Semyanov, A. (2013). Different transporter systems regulate extracellular GABA from vesicular and non-vesicular sources. Front. Cell. Neurosci. 7:23. doi: 10.3389/fncel.2013.00023
    • (2013) Front. Cell. Neurosci , vol.7 , pp. 23
    • Song, I.1    Volynski, K.2    Brenner, T.3    Ushkaryov, Y.4    Walker, M.5    Semyanov, A.6
  • 115
    • 28844434268 scopus 로고    scopus 로고
    • Functionally independent subunits in the oligomeric structure of the GABA cotransporter rGAT1
    • doi: 10.1007/s00018-005-5322-x
    • Soragna, A., Bossi, E., Giovannardi, S., Pisani, R., and Peres, A. (2005). Functionally independent subunits in the oligomeric structure of the GABA cotransporter rGAT1. Cell. Mol. Life Sci. 62, 2877-2885. doi: 10.1007/s00018-005-5322-x
    • (2005) Cell. Mol. Life Sci , vol.62 , pp. 2877-2885
    • Soragna, A.1    Bossi, E.2    Giovannardi, S.3    Pisani, R.4    Peres, A.5
  • 116
    • 84888875140 scopus 로고    scopus 로고
    • Inhibition-induced theta resonance in cortical circuits
    • doi: 10.1016/j.neuron.2013.09.033
    • Stark, E., Eichler, R., Roux, L., Fujisawa, S., Rotstein, H. G., and Buzsaki, G. (2013). Inhibition-induced theta resonance in cortical circuits. Neuron 80, 1263-1276. doi: 10.1016/j.neuron.2013.09.033
    • (2013) Neuron , vol.80 , pp. 1263-1276
    • Stark, E.1    Eichler, R.2    Roux, L.3    Fujisawa, S.4    Rotstein, H.G.5    Buzsaki, G.6
  • 117
    • 0344630208 scopus 로고    scopus 로고
    • Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors
    • doi: 10.1073/pnas.2435457100
    • Stell, B. M., Brickley, S. G., Tang, C. Y., Farrant, M., and Mody, I. (2003). Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors. Proc. Natl. Acad. Sci. U.S.A. 100, 14439-14444. doi: 10.1073/pnas.2435457100
    • (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 14439-14444
    • Stell, B.M.1    Brickley, S.G.2    Tang, C.Y.3    Farrant, M.4    Mody, I.5
  • 118
    • 35548944940 scopus 로고    scopus 로고
    • Different transmitter transients underlie presynaptic cell type specificity of GABAA,slow and GABAA,fast
    • doi: 10.1073/pnas.0707204104
    • Szabadics, J., Tamas, G., and Soltesz, I. (2007). Different transmitter transients underlie presynaptic cell type specificity of GABAA,slow and GABAA,fast. Proc. Natl. Acad. Sci. U.S.A. 104, 14831-14836. doi: 10.1073/pnas.0707204104
    • (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 14831-14836
    • Szabadics, J.1    Tamas, G.2    Soltesz, I.3
  • 119
    • 0017745032 scopus 로고
    • Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum
    • Takai, Y., Kishimoto, A., Inoue, M., and Nishizuka, Y. (1977). Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum. J. Biol. Chem. 252, 7603-7609.
    • (1977) J. Biol. Chem , vol.252 , pp. 7603-7609
    • Takai, Y.1    Kishimoto, A.2    Inoue, M.3    Nishizuka, Y.4
  • 120
    • 0037459320 scopus 로고    scopus 로고
    • Identified sources and targets of slow inhibition in the neocortex
    • doi: 10.1126/science.1082053
    • Tamas, G., Lorincz, A., Simon, A., and Szabadics, J. (2003). Identified sources and targets of slow inhibition in the neocortex. Science 299, 1902-1905. doi: 10.1126/science.1082053
    • (2003) Science , vol.299 , pp. 1902-1905
    • Tamas, G.1    Lorincz, A.2    Simon, A.3    Szabadics, J.4
  • 121
    • 79957613599 scopus 로고    scopus 로고
    • MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
    • doi: 10.1093/molbev/msr121
    • Tamura, K., Peterson, D., Peterson, N., Stecher, G., Nei, M., and Kumar, S. (2011). MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 28, 2731-2739. doi: 10.1093/molbev/msr121
    • (2011) Mol. Biol. Evol , vol.28 , pp. 2731-2739
    • Tamura, K.1    Peterson, D.2    Peterson, N.3    Stecher, G.4    Nei, M.5    Kumar, S.6
  • 122
    • 0026771403 scopus 로고
    • Effects of the GABA uptake inhibitor tiagabine on inhibitory synaptic potentials in rat hippocampal slice cultures
    • Thompson, S. M., and Gahwiler, B. H. (1992). Effects of the GABA uptake inhibitor tiagabine on inhibitory synaptic potentials in rat hippocampal slice cultures. J. Neurophysiol. 67, 1698-1701.
    • (1992) J. Neurophysiol , vol.67 , pp. 1698-1701
    • Thompson, S.M.1    Gahwiler, B.H.2
  • 123
    • 33750470835 scopus 로고    scopus 로고
    • Activation of a presynaptic glutamate transporter regulates synaptic transmission through electrical signaling
    • doi: 10.1038/nn1793
    • Veruki, M. L., Mørkve, S. H., and Hartveit, E. (2006). Activation of a presynaptic glutamate transporter regulates synaptic transmission through electrical signaling. Nat. Neurosci. 9, 1388-1396. doi: 10.1038/nn1793
    • (2006) Nat. Neurosci , vol.9 , pp. 1388-1396
    • Veruki, M.L.1    Mørkve, S.H.2    Hartveit, E.3
  • 124
    • 0141887415 scopus 로고    scopus 로고
    • Expression of GABA transporters, GAT-1 and GAT-3, in the cerebral cortex and thalamus of the rat during postnatal development
    • doi: 10.1007/s00441-003-0746-9
    • Vitellaro-Zuccarello, L., Calvaresi, N., and De Biasi, S. (2003). Expression of GABA transporters, GAT-1 and GAT-3, in the cerebral cortex and thalamus of the rat during postnatal development. Cell Tissue Res. 313, 245-257. doi: 10.1007/s00441-003-0746-9
    • (2003) Cell Tissue Res , vol.313 , pp. 245-257
    • Vitellaro-Zuccarello, L.1    Calvaresi, N.2    de Biasi, S.3
  • 125
    • 0029142729 scopus 로고
    • Ion fluxes associated with excitatory amino acid transport
    • doi: 10.1016/0896-6273(95)90159-0
    • Wadiche, J. I., Amara, S. G., and Kavanaugh, M. P. (1995). Ion fluxes associated with excitatory amino acid transport. Neuron 15, 721-728. doi: 10.1016/0896-6273(95)90159-0
    • (1995) Neuron , vol.15 , pp. 721-728
    • Wadiche, J.I.1    Amara, S.G.2    Kavanaugh, M.P.3
  • 126
    • 0035900674 scopus 로고    scopus 로고
    • Substrate-induced regulation of gamma-aminobutyric acid transporter trafficking requires tyrosine phosphorylation
    • doi: 10.1074/jbc.M10 7638200
    • Whitworth, T. L., and Quick, M. W. (2001). Substrate-induced regulation of gamma-aminobutyric acid transporter trafficking requires tyrosine phosphorylation. J. Biol. Chem. 276, 42932-42937. doi: 10.1074/jbc.M10 7638200
    • (2001) J. Biol. Chem , vol.276 , pp. 42932-42937
    • Whitworth, T.L.1    Quick, M.W.2
  • 127
    • 84888419468 scopus 로고    scopus 로고
    • Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3
    • doi: 10.3389/fncir.2013.00188
    • Wojtowicz, A. M., Dvorzhak, A., Semtner, M., and Grantyn, R. (2013). Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3. Front. Neural Circuits 7:188. doi: 10.3389/fncir.2013.00188
    • (2013) Front. Neural Circuits , vol.7 , pp. 188
    • Wojtowicz, A.M.1    Dvorzhak, A.2    Semtner, M.3    Grantyn, R.4
  • 128
    • 36549066615 scopus 로고    scopus 로고
    • Nonvesicular inhibitory neurotransmission via reversal of the GABA transporter GAT-1
    • doi: 10.1016/j.neuron.2007.10.021
    • Wu, Y., Wang, W., Diez-Sampedro, A., and Richerson, G. B. (2007). Nonvesicular inhibitory neurotransmission via reversal of the GABA transporter GAT-1. Neuron 56, 851-865. doi: 10.1016/j.neuron.2007.10.021
    • (2007) Neuron , vol.56 , pp. 851-865
    • Wu, Y.1    Wang, W.2    Diez-Sampedro, A.3    Richerson, G.B.4
  • 129
    • 24644470065 scopus 로고    scopus 로고
    • Crystal structure of a bacterial homologue of Na+/Cl-dependent neurotransmitter transporters
    • doi: 10.1038/nature03978
    • Yamashita, A., Singh, S. K., Kawate, T., Jin, Y., and Gouaux, E. (2005). Crystal structure of a bacterial homologue of Na+/Cl-dependent neurotransmitter transporters. Nature 437, 215-223. doi: 10.1038/nature03978
    • (2005) Nature , vol.437 , pp. 215-223
    • Yamashita, A.1    Singh, S.K.2    Kawate, T.3    Jin, Y.4    Gouaux, E.5
  • 130
    • 0031058314 scopus 로고    scopus 로고
    • Immunoreactivity for GABA plasma membrane transporter, GAT-1, in the developing rat cerebral cortex: Transient presence in the somata of neocortical and hippocampal neurons
    • doi: 10.1016/S0165-3806(96) 00192-7
    • Yan, X. X., Cariaga, W. A., and Ribak, C. E. (1997). Immunoreactivity for GABA plasma membrane transporter, GAT-1, in the developing rat cerebral cortex: transient presence in the somata of neocortical and hippocampal neurons. Brain Res. Dev. Brain Res. 99, 1-19. doi: 10.1016/S0165-3806(96) 00192-7
    • (1997) Brain Res. Dev. Brain Res , vol.99 , pp. 1-19
    • Yan, X.X.1    Cariaga, W.A.2    Ribak, C.E.3
  • 131
    • 20144378948 scopus 로고    scopus 로고
    • Transporter-associated currents in the gamma-aminobutyric acid transporter GAT-1 are conditionally impaired by mutations of a conserved glycine residue
    • doi: 10.1074/jbc.M412937200
    • Zhou, Y., and Kanner, B. I. (2005). Transporter-associated currents in the gamma-aminobutyric acid transporter GAT-1 are conditionally impaired by mutations of a conserved glycine residue. J. Biol. Chem. 280, 20316-20324. doi: 10.1074/jbc.M412937200
    • (2005) J. Biol. Chem , vol.280 , pp. 20316-20324
    • Zhou, Y.1    Kanner, B.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.