Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs

British Journal of Pharmacology

Volumn 128, Issue 1, 1999, Pages 92-102

  Eckstein Ludwig, Ursula ^a,b   Fei, Jian ^a,c   Schwarz, Wolfgang ^a  

^a MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Electrophysiology; Epilepsy; GABA transporter; Gabapentin; Tiagabine; Valproate; Vigabatrin; Xenopus oocyte

Indexed keywords

4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; CARRIER PROTEIN; GABAPENTIN; TIAGABINE; VALPROIC ACID; VIGABATRIN;

4 AMINOBUTYRIC ACID UPTAKE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; FEMALE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; STEADY STATE; SYNAPSE; XENOPUS;

ACETIC ACIDS; AMINES; ANIMALS; ANTICONVULSANTS; BINDING SITES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CYCLOHEXANECARBOXYLIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; FEMALE; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; KINETICS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; NIPECOTIC ACIDS; OOCYTES; ORGANIC ANION TRANSPORTERS; PATCH-CLAMP TECHNIQUES; VALPROIC ACID; VIGABATRIN; XENOPUS LAEVIS;

EID: 0032869610     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702794     Document Type: Article

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