Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

Blood

Volumn 123, Issue 24, 2014, Pages 3750-3759

  Xu, Yang ^a,b   Zhang, Ming ^a   Ramos, Carlos A ^a,b,c   Durett, April ^a   Liu, Enli ^a   Dakhova, Olga ^a   Liu, Hao ^b   Creighton, Chad J ^b   Gee, Adrian P ^a,b   Heslop, Helen E ^a,b,c,d   Rooney, Cliona M ^a,b,d   Savoldo, Barbara ^a,b,d   Dotti, Gianpietro ^a,b,d  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c HOUSTON METHODIST HOSPITAL   (United States)

^d TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CD19 SPECIFIC CHIMERIC ANTIGEN RECEPTOR; CD28 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR7; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 7; RETROVIRUS VECTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; B CELL LYMPHOMA; CD4 CD8 RATIO; CELL DEATH; CELL EXPANSION; CELL MIGRATION; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; CYTOTOXICITY; EX VIVO STUDY; GENE EXPRESSION; HUMAN; IN VIVO STUDY; MEMORY; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STEM CELL; T LYMPHOCYTE SUBPOPULATION;

ADOPTIVE TRANSFER; ADULT STEM CELLS; ANIMALS; ANTIGENS, CD19; CELL PROLIFERATION; CELLS, CULTURED; GENETIC THERAPY; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-15; INTERLEUKIN-7; LYMPHOCYTE ACTIVATION; LYMPHOMA; MICE; MICE, SCID; MICE, TRANSGENIC; RECEPTORS, ANTIGEN; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES;

EID: 84902590274     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-01-552174     Document Type: Article

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