Thermally triggered release of a pro-osteogenic peptide from a functionalized collagen-based scaffold using thermosensitive liposomes

Journal of Controlled Release

Volumn 187, Issue , 2014, Pages 158-166

  López Noriega, Adolfo ^a,b   Ruiz Hernández, Eduardo ^a,b,c   Quinlan, Elaine ^a,b   Storm, Gert ^c,d   Hennink, Wim E ^c   O'Brien, Fergal J ^a,b  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Collagen; Drug delivery; Scaffold; Thermally responsive material; Thermosensitive liposomes; Tissue engineering

Indexed keywords

BIOCOMPATIBILITY; COLLAGEN; DRUG DELIVERY; GENE EXPRESSION; LIPOSOMES; PHOSPHATASES; SCAFFOLDS; TISSUE ENGINEERING; TOXIC MATERIALS;

ALKALINE PHOSPHATASE ACTIVITY; COLLAGEN-BASED SCAFFOLDS; KINETICS OF RELEASE; ON-DEMAND RELEASE; THERMALLY RESPONSIVE MATERIAL; THERMO-RESPONSIVE; THERMOSENSITIVE LIPOSOMES; TRIGGERED RELEASE;

SCAFFOLDS (BIOLOGY);

ALKALINE PHOSPHATASE; BONE DENSITY CONSERVATION AGENT; COLLAGEN DERIVATIVE; HYDROXYAPATITE; LIPOSOME; OSTEOCALCIN; OSTEOPONTIN; PARATHYROID HORMONE RELATED PROTEIN; PTHRP 107 111; UNCLASSIFIED DRUG; COLLAGEN; PEPTIDE FRAGMENT;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; BONE REMODELING; CELL ADHESION; CELL PROLIFERATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; COVALENT BOND; EMBRYO; ENZYME ACTIVITY; HEAT SENSITIVITY; HYPERTHERMIA; IN VITRO STUDY; LIPOSOMAL DELIVERY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURFACE PROPERTY; THERMAL STIMULATION; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; HEAT; TISSUE SCAFFOLD;

ANIMALS; CELL LINE; COLLAGEN; DURAPATITE; HOT TEMPERATURE; LIPOSOMES; MICE; OSTEOGENESIS; PEPTIDE FRAGMENTS; TISSUE SCAFFOLDS;

EID: 84902581306     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.05.043     Document Type: Article

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