메뉴 건너뛰기




Volumn 161, Issue , 2012, Pages 515-534

Materials characterization of the low temperature sensitive liposome (LTSL): Effects of the lipid composition (lysolipid and DSPE-PEG2000) on the thermal transition and release of doxorubicin

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84880503720     PISSN: 13596640     EISSN: 13645498     Source Type: Journal    
DOI: 10.1039/c2fd20111a     Document Type: Article
Times cited : (114)

References (81)
  • 1
    • 84868256944 scopus 로고    scopus 로고
    • A new paradigm for drug delivery to tumors: The importance of triggered intravascular drug release from thermally-sensitive liposomes as a mechanism to enhance drug penetration distance
    • 10.1158/0008-5472.CAN-12-1683
    • A. A. Manzoor Lars H. Lindner Ji-Young Park Andrew J. Simnick Matthew R. Dreher Shiva Das Gabi Hanna Won Park Gerben Koning Timo ten Hagen David Needham Mark W. Dewhirst A new paradigm for drug delivery to tumors: the importance of triggered intravascular drug release from thermally-sensitive liposomes as a mechanism to enhance drug penetration distance J. Natl Cancer Inst 2012 10.1158/0008-5472.CAN-12-1683
    • (2012) J. Natl Cancer Inst
    • Manzoor, A.A.1    Lindner, L.H.2    Park, J.-Y.3    Simnick, A.J.4    Dreher, M.R.5    Das, S.6    Hanna, G.7    Park, W.8    Koning, G.9    Hagen, T.T.10    Needham, D.11    Dewhirst, M.W.12
  • 2
    • 0023788067 scopus 로고
    • Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules
    • H. F. Dvorak et al., Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules Am J Pathol 1988 133 1 95 109
    • (1988) Am J Pathol , vol.133 , Issue.1 , pp. 95-109
    • Dvorak, H.F.1
  • 3
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • H. Maeda The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting Adv. Enzyme Regul. 2001 41 189 207
    • (2001) Adv. Enzyme Regul. , vol.41 , pp. 189-207
    • Maeda, H.1
  • 4
    • 0024839642 scopus 로고
    • Tumoritropic and lymphotropic principles of macromolecular drugs
    • H. A. Y. M. Maeda Tumoritropic and lymphotropic principles of macromolecular drugs Crit. Rev. Ther. Drug Carrier Sys. 1989 6 193 210
    • (1989) Crit. Rev. Ther. Drug Carrier Sys. , vol.6 , pp. 193-210
    • Maeda, H.A.Y.M.1
  • 5
    • 0028304405 scopus 로고
    • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
    • F. Yuan M. Leunig S. K. Huang D. A. Berk D. Papahadjopoulos R. K. Jain Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft Cancer Res 1994 54 3352 6
    • (1994) Cancer Res , vol.54 , pp. 3352-3356
    • Yuan, F.1    Leunig, M.2    Huang, S.K.3    Berk, D.A.4    Papahadjopoulos, D.5    Jain, R.K.6
  • 6
    • 0027242138 scopus 로고
    • Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue
    • D. D. Wu NZ T. L. Rudoll D. Needham A. R. Whorton M. W. Dewhirst Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue Cancer Res 1993 53 3765 70
    • (1993) Cancer Res , vol.53 , pp. 3765-3770
    • Wu Nz, D.D.1    Rudoll, T.L.2    Needham, D.3    Whorton, A.R.4    Dewhirst, M.W.5
  • 7
    • 0030444874 scopus 로고    scopus 로고
    • Thermosensitive liposomes: Extravasation and release of contents in tumor microvascular networks
    • M. H. Gaber et al., Thermosensitive liposomes: Extravasation and release of contents in tumor microvascular networks Int. J. Radiat. Oncol., Biol., Phys. 1996 36 5 1177 1187
    • (1996) Int. J. Radiat. Oncol., Biol., Phys. , vol.36 , Issue.5 , pp. 1177-1187
    • Gaber, M.H.1
  • 8
    • 0034662609 scopus 로고    scopus 로고
    • Hyperthermia enables tumorspecific nanoparticle delivery: Effect of particle size
    • G. Kong R. D. Braun M. W. Dewhirst Hyperthermia enables tumorspecific nanoparticle delivery: effect of particle size Cancer Res 2000 60 4440 5
    • (2000) Cancer Res , vol.60 , pp. 4440-4445
    • Kong, G.1    Braun, R.D.2    Dewhirst, M.W.3
  • 9
    • 0035300546 scopus 로고    scopus 로고
    • Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature
    • G. Kong R. D. Braun M. W. Dewhirst Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature Cancer Res 2001 61 3027 32
    • (2001) Cancer Res , vol.61 , pp. 3027-3032
    • Kong, G.1    Braun, R.D.2    Dewhirst, M.W.3
  • 10
    • 54449095389 scopus 로고    scopus 로고
    • Tumor microvascular permeability is a key determinant for antivascular effects of doxorubicin encapsulated in a temperature sensitive liposome
    • Q. Chen et al., Tumor microvascular permeability is a key determinant for antivascular effects of doxorubicin encapsulated in a temperature sensitive liposome Int. J. Hyperthermia 2008 24 6 475 82
    • (2008) Int. J. Hyperthermia , vol.24 , Issue.6 , pp. 475-482
    • Chen, Q.1
  • 11
    • 85012373035 scopus 로고
    • Diffusion of univalent ions across the lamellae of swollen phospholipids
    • A. D. Bangham M. M. Standish J. C. Watkins Diffusion of univalent ions across the lamellae of swollen phospholipids J. Mol. Biol. 1965 13 1 238 52
    • (1965) J. Mol. Biol. , vol.13 , Issue.1 , pp. 238-252
    • Bangham, A.D.1    Standish, M.M.2    Watkins, J.C.3
  • 12
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: Entering the mainstream
    • T. Allen P. Cullis Drug delivery systems: entering the mainstream Science 2004 303 1818 22
    • (2004) Science , vol.303 , pp. 1818-1822
    • Allen, T.1    Cullis, P.2
  • 14
    • 0034161921 scopus 로고    scopus 로고
    • A New Temperature-Sensitive Liposome for Use with Mild Hyperthermia: Characterization and Testing in a Human Tumor Xenograft Model
    • D. Needham G. Anyarambhatla G. Kong M. W. Dewhirst A New Temperature-Sensitive Liposome for Use with Mild Hyperthermia: Characterization and Testing in a Human Tumor Xenograft Model Cancer Research 2000 60 5 1197 1201
    • (2000) Cancer Research , vol.60 , Issue.5 , pp. 1197-1201
    • Needham, D.1    Anyarambhatla, G.2    Kong, G.3    Dewhirst, M.W.4
  • 15
    • 85132526751 scopus 로고    scopus 로고
    • Nanoscale Drug Delivery Vehicles for Solid Tumors: A New Paradigm for Localized Drug Delivery Using Temperature Sensitive Liposomes
    • in, ed. M.M. Amiji, CRC Press, Boca Raton, FL
    • D. Needham and Ana Ponce, Nanoscale Drug Delivery Vehicles for Solid Tumors: A New Paradigm for Localized Drug Delivery Using Temperature Sensitive Liposomes, in Nanotechnology for Cancer Therapy, ed., M.M. Amiji, CRC Press, Boca Raton, FL, 2006, pp. 677-719
    • (2006) Nanotechnology for Cancer Therapy , pp. 677-719
    • Needham, D.1    Ponce, A.2
  • 16
    • 84883016073 scopus 로고    scopus 로고
    • ClinicalTrials.gov. Phase 1/2 Study of ThermoDox With Approved Hyperthermia in Treatment of Breast Cancer Recurrence at the Chest Wall (DIGNITY), 2010, available from
    • ClinicalTrials.gov. Phase 1/2 Study of ThermoDox With Approved Hyperthermia in Treatment of Breast Cancer Recurrence at the Chest Wall (DIGNITY), 2010, available from: http://www.clinicaltrials.gov/ct2/show/ NCT00826085?term=thermodox+rcw&rank=1
  • 17
    • 84882996814 scopus 로고    scopus 로고
    • ClinicalTrials.gov. A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the Liver, 2010, available from
    • ClinicalTrials.gov. A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the Liver, 2010, available from: http://www.clinicaltrials.gov/ct2/show/NCT00441376?term= thermodox+RFA+liver&rank=1
  • 18
    • 84882947114 scopus 로고    scopus 로고
    • ClinicalTrials.gov. Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC), 2010, available from
    • ClinicalTrials.gov. Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC), 2010, available from: http://www.clinicaltrials.gov/ct2/show/NCT00617981?term= NCT00617981&rank=1
  • 21
    • 27444434694 scopus 로고    scopus 로고
    • Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition
    • J. K. Mills D. Needham Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition Biochim. Biophys. Acta, Biomembr. 2005 1716 2 77 96
    • (2005) Biochim. Biophys. Acta, Biomembr. , vol.1716 , Issue.2 , pp. 77-96
    • Mills, J.K.1    Needham, D.2
  • 22
    • 0019460549 scopus 로고
    • Selective delivery of liposome-associated cis- dichlorodiammineplatinum(II) by heat and its influence on tumor drug uptake and growth
    • M. B. Yatvin et al., Selective delivery of liposome-associated cis-dichlorodiammineplatinum(II) by heat and its influence on tumor drug uptake and growth Cancer Res 1981 41 5 1602 7
    • (1981) Cancer Res , vol.41 , Issue.5 , pp. 1602-1607
    • Yatvin, M.B.1
  • 23
    • 0032881383 scopus 로고    scopus 로고
    • Hyperthermia and liposomes
    • G. Kong et al., Hyperthermia and liposomes Int. J. Hyperthermia 1999 15 5 345 70
    • (1999) Int. J. Hyperthermia , vol.15 , Issue.5 , pp. 345-370
    • Kong, G.1
  • 24
    • 84883020091 scopus 로고    scopus 로고
    • Celsion, 2010 [accessed August 8, 2010]. Available from
    • Celsion, 2010 [accessed August 8, 2010]. Available from: http://www.celsion.com
  • 25
    • 0032776319 scopus 로고    scopus 로고
    • Enhancement of the phase transition permeability of DPPC liposomes by incorporation of MPPC: A new temperature-sensitive liposome for use with mild hyperthermia
    • G. R. Anyarambhatla et al., Enhancement of the phase transition permeability of DPPC liposomes by incorporation of MPPC: A new temperature-sensitive liposome for use with mild hyperthermia J. Liposome Res. 1999 9 4 491 506
    • (1999) J. Liposome Res. , vol.9 , Issue.4 , pp. 491-506
    • Anyarambhatla, G.R.1
  • 26
    • 0034671219 scopus 로고    scopus 로고
    • Efficacy of liposomes and hyperthermia in a human tumor xenograft model: Importance of triggered drug release
    • G. Kong et al., Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release Cancer Res 2000 60 24 6950 7
    • (2000) Cancer Res , vol.60 , Issue.24 , pp. 6950-6957
    • Kong, G.1
  • 27
    • 3142667914 scopus 로고    scopus 로고
    • The materials engineering of temperature-sensitive liposomes
    • J. K. Mills et al., The materials engineering of temperature-sensitive liposomes Methods Enzymol. 2004 387 82 113
    • (2004) Methods Enzymol. , vol.387 , pp. 82-113
    • Mills, J.K.1
  • 28
    • 0034161921 scopus 로고    scopus 로고
    • A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in a human tumor xenograft model
    • D. Needham et al., A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model Cancer Res 2000 60 5 1197 201
    • (2000) Cancer Res , vol.60 , Issue.5 , pp. 1197-1201
    • Needham, D.1
  • 29
    • 0035981024 scopus 로고    scopus 로고
    • The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors
    • D. Needham et al., The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors Adv. Drug Delivery Rev. 2001 53 3 285 305
    • (2001) Adv. Drug Delivery Rev. , vol.53 , Issue.3 , pp. 285-305
    • Needham, D.1
  • 31
    • 27444434694 scopus 로고    scopus 로고
    • Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition
    • J. K. Mills et al., Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition Biochim. Biophys. Acta, Biomembr. 2005 1716 2 77 96
    • (2005) Biochim. Biophys. Acta, Biomembr. , vol.1716 , Issue.2 , pp. 77-96
    • Mills, J.K.1
  • 32
    • 0015795402 scopus 로고
    • Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol
    • D. Papahadjopoulos et al., Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol Biochim. Biophys. Acta, Biomembr. 1973 311 3 330 48
    • (1973) Biochim. Biophys. Acta, Biomembr. , vol.311 , Issue.3 , pp. 330-348
    • Papahadjopoulos, D.1
  • 33
    • 0032776319 scopus 로고    scopus 로고
    • Enhancement of the Phase Transition Permeability of DPPC Liposomes by Incorporation of MPPC: A New Temperature-Sensitive Liposome for use with Mild Hyperthermia
    • G. R. Anyarambhatla et al., Enhancement of the Phase Transition Permeability of DPPC Liposomes by Incorporation of MPPC: A New Temperature-Sensitive Liposome for use with Mild Hyperthermia J. Liposome Res. 1999 9 4 491 506
    • (1999) J. Liposome Res. , vol.9 , Issue.4 , pp. 491-506
    • Anyarambhatla, G.R.1
  • 34
    • 3142667914 scopus 로고    scopus 로고
    • The materials engineering of temperature sensitive liposomes
    • J. K. Mills D. Needham The materials engineering of temperature sensitive liposomes Methods Enzymol. 2004 387 82 113
    • (2004) Methods Enzymol. , vol.387 , pp. 82-113
    • Mills, J.K.1    Needham, D.2
  • 35
    • 84882953014 scopus 로고    scopus 로고
    • Drug loading and release from a thermally sensitive liposome
    • in, Duke University, Durham
    • A. Wright, Drug loading and release from a thermally sensitive liposome, in Mechanical Engineering and Materials Science, Duke University, Durham, 2006
    • (2006) Mechanical Engineering and Materials Science
    • Wright, A.1
  • 36
    • 84883030795 scopus 로고    scopus 로고
    • Chelsea Landon, Fatema Ahmad, Runjhun Srivistava, Mark W Dewhirst, David Needham, Formulatation of Cisplatin containing Lysolipid Temperature-Sensitive Liposomes and their Drug Release Kinetics
    • in preparation
    • J.-Y. Park Chelsea Landon, Fatema Ahmad, Runjhun Srivistava, Mark W Dewhirst, David Needham, Formulatation of Cisplatin containing Lysolipid Temperature-Sensitive Liposomes and their Drug Release Kinetics Journal of Liposome Research 2012
    • (2012) Journal of Liposome Research
    • Park, J.-Y.1
  • 37
    • 65649146495 scopus 로고    scopus 로고
    • Lyso-thermosensitive liposomal doxorubicin: A novel approach to enhance efficacy of thermal ablation of liver cancer
    • R. T. Poon N. Borys Lyso-thermosensitive liposomal doxorubicin: a novel approach to enhance efficacy of thermal ablation of liver cancer Expert Opin. Pharmacother. 2009 10 2 333 43
    • (2009) Expert Opin. Pharmacother. , vol.10 , Issue.2 , pp. 333-343
    • Poon, R.T.1    Borys, N.2
  • 38
    • 84957794434 scopus 로고
    • Filtration, Diffusion and molecular sieving through peripheral capillary membranes; A contribution to the pore theory of capillary permeability
    • J. R. Pappenheimer E. M. Renkin L. M. Borrero Filtration, Diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability Am J Physiol 1951 167 1 13 46
    • (1951) Am J Physiol , vol.167 , Issue.1 , pp. 13-46
    • Pappenheimer, J.R.1    Renkin, E.M.2    Borrero, L.M.3
  • 39
    • 84883006345 scopus 로고    scopus 로고
    • Chest Wall Recurrence of Breast Cancer Treated with Hyperthermia and Thermally Sensitive Liposomes (ThermoDox)
    • ClinicalTrials.gov., available from
    • ClinicalTrials.gov. Z. Vujaskovic, Chest Wall Recurrence of Breast Cancer Treated with Hyperthermia and Thermally Sensitive Liposomes (ThermoDox), Society for Thermal Medicine, 2007, available from http://www.clinicaltrials. gov/ct2/show/NCT00346229?term=NCT00346229&rank=1
    • (2007) Society for Thermal Medicine
    • Vujaskovic, Z.1
  • 40
    • 77954394371 scopus 로고    scopus 로고
    • A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer
    • Z. Vujaskovic et al., A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer Int. J. Hyperthermia 2010 26 5 514 21
    • (2010) Int. J. Hyperthermia , vol.26 , Issue.5 , pp. 514-521
    • Vujaskovic, Z.1
  • 42
    • 84882953014 scopus 로고    scopus 로고
    • Drug loading and release from a thermally sensitive liposome
    • in, Duke University, Durham
    • A. M. Wright, Drug loading and release from a thermally sensitive liposome, in Mechanical Engineering and Materials Science, Duke University, Durham, 2006, pp. 1-322
    • (2006) Mechanical Engineering and Materials Science , pp. 1-322
    • Wright, A.M.1
  • 44
    • 0022545773 scopus 로고
    • Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient
    • L. D. Mayer et al., Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient Biochim. Biophys. Acta, Biomembr. 1986 857 1 123 6
    • (1986) Biochim. Biophys. Acta, Biomembr. , vol.857 , Issue.1 , pp. 123-126
    • Mayer, L.D.1
  • 45
    • 84883010533 scopus 로고    scopus 로고
    • Session 05: Amphiphilic membranes and templates. Lipid membranes: Biological inspiration for micro and nano encapsulation technologies, especially drug delivery, in, Materials Research Society, San Francisco
    • D. Needham, Session 05: Amphiphilic membranes and templates. Lipid membranes: Biological inspiration for micro and nano encapsulation technologies, especially drug delivery, in Materials Research Society, Materials Research Society, San Francisco, 2003
    • (2003) Materials Research Society
    • Needham, D.1
  • 46
    • 3142667914 scopus 로고    scopus 로고
    • The materials engineering of temperature-sensitive liposomes
    • J. K. Mills D. Needham The materials engineering of temperature-sensitive liposomes Methods Enzymol 2004 387 82 113
    • (2004) Methods Enzymol , vol.387 , pp. 82-113
    • Mills, J.K.1    Needham, D.2
  • 47
    • 0021909644 scopus 로고
    • Production of Large Unilamellar Vesicles by a Rapid Extrusion Procedure - Characterization of Size Distribution, Trapped Volume and Ability to Maintain a Membrane-Potential
    • M. J. Hope et al., Production of Large Unilamellar Vesicles by a Rapid Extrusion Procedure-Characterization of Size Distribution, Trapped Volume and Ability to Maintain a Membrane-Potential Biochim. Biophys. Acta, Biomembr. 1985 812 1 55 65
    • (1985) Biochim. Biophys. Acta, Biomembr. , vol.812 , Issue.1 , pp. 55-65
    • Hope, M.J.1
  • 48
    • 0023047980 scopus 로고
    • Vesicles of variable sizes produced by a rapid extrusion procedure
    • L. D. Mayer et al., Vesicles of variable sizes produced by a rapid extrusion procedure Biochim. Biophys. Acta, Biomembr. 1986 858 1 161 168
    • (1986) Biochim. Biophys. Acta, Biomembr. , vol.858 , Issue.1 , pp. 161-168
    • Mayer, L.D.1
  • 49
    • 0018827529 scopus 로고
    • Water permeability of lipid membranes
    • R. Fettiplace et al., Water permeability of lipid membranes Physiol Rev 1980 60 2 510 550
    • (1980) Physiol Rev , vol.60 , Issue.2 , pp. 510-550
    • Fettiplace, R.1
  • 50
    • 0027433668 scopus 로고
    • Optimization of the retention properties of vincristine in liposomal systems
    • N. L. Boman et al., Optimization of the retention properties of vincristine in liposomal systems Biochim. Biophys. Acta, Biomembr. 1993 1152 2 253 258
    • (1993) Biochim. Biophys. Acta, Biomembr. , vol.1152 , Issue.2 , pp. 253-258
    • Boman, N.L.1
  • 52
    • 0025278891 scopus 로고
    • The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: A survey
    • T. D. Madden et al., The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey Chem. Phys. Lipids 1990 53 1 37 46
    • (1990) Chem. Phys. Lipids , vol.53 , Issue.1 , pp. 37-46
    • Madden, T.D.1
  • 53
    • 0028324117 scopus 로고
    • Ammonium sulfate gradients for efficient and stable remote loading of amphipathic weak bases into liposomes and ligandoliposomes
    • E. Bolotin et al., Ammonium sulfate gradients for efficient and stable remote loading of amphipathic weak bases into liposomes and ligandoliposomes J. Liposome Res. 1994 4 1 455 479
    • (1994) J. Liposome Res. , vol.4 , Issue.1 , pp. 455-479
    • Bolotin, E.1
  • 54
    • 0037144125 scopus 로고    scopus 로고
    • Triggered release of doxorubicin following mixing of cationic and anionic liposomes
    • I. V. Zhigaltsev et al., Triggered release of doxorubicin following mixing of cationic and anionic liposomes. Biochim. Biophys. Acta, Biomembr. 2002 1565 1 129 135
    • (2002) Biochim. Biophys. Acta, Biomembr. , vol.1565 , Issue.1 , pp. 129-135
    • Zhigaltsev, I.V.1
  • 55
    • 0034969095 scopus 로고    scopus 로고
    • Factors affecting leakage of trapped solutes from phospholipid vesicles during thermotropic phase transitions
    • L. M. Hays Factors affecting leakage of trapped solutes from phospholipid vesicles during thermotropic phase transitions Cryobiology 2001 42 2 88 102
    • (2001) Cryobiology , vol.42 , Issue.2 , pp. 88-102
    • Hays, L.M.1
  • 56
    • 0041508371 scopus 로고    scopus 로고
    • Lipid membranes with grafted polymers: Physicochemical aspects
    • D. Marsh et al., Lipid membranes with grafted polymers: physicochemical aspects Biochim. Biophys. Acta, Biomembr. 2003 1615 1-2 33 59
    • (2003) Biochim. Biophys. Acta, Biomembr. , vol.1615 , Issue.12 , pp. 33-59
    • Marsh, D.1
  • 57
    • 0032457921 scopus 로고    scopus 로고
    • Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient
    • X. Li et al., Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient Biochim. Biophys. Acta, Biomembr. 1998 1415 1 23 40
    • (1998) Biochim. Biophys. Acta, Biomembr. , vol.1415 , Issue.1 , pp. 23-40
    • Li, X.1
  • 58
    • 0028964069 scopus 로고
    • Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol)
    • A. K. Kenworthy et al., Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol) Biophys. J. 1995 68 5 1921 36
    • (1995) Biophys. J. , vol.68 , Issue.5 , pp. 1921-1936
    • Kenworthy, A.K.1
  • 59
    • 0018250922 scopus 로고
    • Design of liposomes for enhanced local release of drugs by hyperthermia
    • M. B. Yatvin et al., Design of liposomes for enhanced local release of drugs by hyperthermia Science 1978 202 4374 1290 3
    • (1978) Science , vol.202 , Issue.4374 , pp. 1290-1293
    • Yatvin, M.B.1
  • 60
    • 1642392535 scopus 로고    scopus 로고
    • Novel temperature-sensitive liposomes with prolonged circulation time
    • L. H. Lindner et al., Novel temperature-sensitive liposomes with prolonged circulation time Clin. Cancer Res. 2004 10 6 2168 78
    • (2004) Clin. Cancer Res. , vol.10 , Issue.6 , pp. 2168-2178
    • Lindner, L.H.1
  • 61
    • 37349024980 scopus 로고    scopus 로고
    • Dual role of hexadecylphosphocholine (miltefosine) in thermosensitive liposomes: Active ingredient and mediator of drug release
    • L. H. Lindner et al., Dual role of hexadecylphosphocholine (miltefosine) in thermosensitive liposomes: active ingredient and mediator of drug release J. Controlled Release 2008 125 2 112 20
    • (2008) J. Controlled Release , vol.125 , Issue.2 , pp. 112-120
    • Lindner, L.H.1
  • 62
    • 79958244584 scopus 로고    scopus 로고
    • Efficient tumor regression by a single and low dose treatment with a novel and enhanced formulation of thermosensitive liposomal doxorubicin
    • T. Tagami et al., Efficient tumor regression by a single and low dose treatment with a novel and enhanced formulation of thermosensitive liposomal doxorubicin J. Controlled Release 2011 152 2 303 309
    • (2011) J. Controlled Release , vol.152 , Issue.2 , pp. 303-309
    • Tagami, T.1
  • 63
    • 80052521281 scopus 로고    scopus 로고
    • Optimization of a novel and improved thermosensitive liposome formulated with DPPC and a Brij surfactant using a robust in vitro system
    • T. Tagami et al., Optimization of a novel and improved thermosensitive liposome formulated with DPPC and a Brij surfactant using a robust in vitro system J. Controlled Release 2011 154 3 290 297
    • (2011) J. Controlled Release , vol.154 , Issue.3 , pp. 290-297
    • Tagami, T.1
  • 65
    • 0032704360 scopus 로고    scopus 로고
    • Fluorescence Quenching and Size Selective Heterodimerization of a Porphyrin Adsorbed to Gold and Embedded in Rigid Membrane Gaps
    • W. Fudickar et al., Fluorescence Quenching and Size Selective Heterodimerization of a Porphyrin Adsorbed to Gold and Embedded in Rigid Membrane Gaps J. Am. Chem. Soc. 1999 121 41 9539 9545
    • (1999) J. Am. Chem. Soc. , vol.121 , Issue.41 , pp. 9539-9545
    • Fudickar, W.1
  • 66
    • 0037961563 scopus 로고    scopus 로고
    • MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain
    • K. J. Hallock D. K. Lee A. Ramamoorthy MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain Biophys. J. 2003 84 5 3052 3060
    • (2003) Biophys. J. , vol.84 , Issue.5 , pp. 3052-3060
    • Hallock, K.J.1    Lee, D.K.2    Ramamoorthy, A.3
  • 67
    • 0019093547 scopus 로고
    • Characterization of collagenous meshworks by volume exclusion of dextrans
    • J. L. Bert et al., Characterization of collagenous meshworks by volume exclusion of dextrans Biochem J 1980 191 3 761 768
    • (1980) Biochem J , vol.191 , Issue.3 , pp. 761-768
    • Bert, J.L.1
  • 68
    • 0021100162 scopus 로고
    • Nuclear envelope permeability measured by fluorescence microphotolysis of single liver cell nuclei
    • R. Peters Nuclear envelope permeability measured by fluorescence microphotolysis of single liver cell nuclei J Biol Chem 1983 258 19 11427 11429
    • (1983) J Biol Chem , vol.258 , Issue.19 , pp. 11427-11429
    • Peters, R.1
  • 69
    • 0027136083 scopus 로고
    • Hindered diffusion of high molecular weight compounds in brain extracellular microenvironment measured with integrative optical imaging
    • C. Nicholson L. Tao Hindered diffusion of high molecular weight compounds in brain extracellular microenvironment measured with integrative optical imaging Biophys. J. 1993 65 6 2277 2290
    • (1993) Biophys. J. , vol.65 , Issue.6 , pp. 2277-2290
    • Nicholson, C.1    Tao, L.2
  • 70
    • 29444460232 scopus 로고    scopus 로고
    • Diffusion and scaling during early embryonic pattern formation
    • T. E. A. Gregor et al., Diffusion and scaling during early embryonic pattern formation Proc. Natl. Acad. Sci. U. S. A. 2005 102 51 18403 18407
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , Issue.51 , pp. 18403-18407
    • Gregor, T.E.A.1
  • 71
    • 0000560829 scopus 로고
    • Filtration, diffusion, and molecular sieving through porous cellulose membranes
    • E. M. Renkin Filtration, diffusion, and molecular sieving through porous cellulose membranes J Gen Physiol. 1954 38 2 225 243
    • (1954) J Gen Physiol. , vol.38 , Issue.2 , pp. 225-243
    • Renkin, E.M.1
  • 72
    • 0028033733 scopus 로고
    • Transport studies of doxorubicin in model membranes indicate a difference in passive diffusion across and binding at the outer and inner leaflets of the plasma membrane
    • G. Speelmans Transport studies of doxorubicin in model membranes indicate a difference in passive diffusion across and binding at the outer and inner leaflets of the plasma membrane Biochemistry 1994 33 46 13761 13768
    • (1994) Biochemistry , vol.33 , Issue.46 , pp. 13761-13768
    • Speelmans, G.1
  • 73
    • 33748815230 scopus 로고
    • Influence of bilayer fluctuations on the steric interactions between polymer-grafted bilayers
    • K. A. D. N. Hristova Influence of bilayer fluctuations on the steric interactions between polymer-grafted bilayers Liq. Cryst. 1995 18 3 423 430
    • (1995) Liq. Cryst. , vol.18 , Issue.3 , pp. 423-430
    • Hristova, K.A.D.N.1
  • 75
    • 0007638245 scopus 로고
    • Model of interfacial melting
    • O. G. Mouritsen et al., Model of interfacial melting Phys. Rev. Lett. 1987 58 4 389 392
    • (1987) Phys. Rev. Lett. , vol.58 , Issue.4 , pp. 389-392
    • Mouritsen, O.G.1
  • 76
    • 0031863608 scopus 로고    scopus 로고
    • Material property characteristics for lipid bilayers containing lysolipid
    • D. V. Zhelev Material property characteristics for lipid bilayers containing lysolipid Biophys. J. 1998 75 321 330
    • (1998) Biophys. J. , vol.75 , pp. 321-330
    • Zhelev, D.V.1
  • 77
    • 0015521089 scopus 로고
    • Fragility of the permeability barrier of Escherichia coli
    • C. W. Haest et al., Fragility of the permeability barrier of Escherichia coli Biochim. Biophys. Acta, Biomembr. 1972 288 1 43 53
    • (1972) Biochim. Biophys. Acta, Biomembr. , vol.288 , Issue.1 , pp. 43-53
    • Haest, C.W.1
  • 78
    • 79955648510 scopus 로고    scopus 로고
    • Steric stabilisation of self-assembled cubic lyotropic liquid crystalline nanoparticles: High throughput evaluation of triblock polyethylene oxide-polypropylene oxide-polyethylene oxide copolymers
    • J. Y. T. Chong Xavier Mulet Lynne J. Waddington Ben J. Boyd Calum J. Drummond Steric stabilisation of self-assembled cubic lyotropic liquid crystalline nanoparticles: high throughput evaluation of triblock polyethylene oxide-polypropylene oxide-polyethylene oxide copolymers Soft Matter 2011 7 4768
    • (2011) Soft Matter , vol.7 , pp. 4768
    • Chong, J.Y.T.1    Mulet, X.2    Waddington, L.J.3    Boyd, B.J.4    Drummond, C.J.5
  • 79
    • 70349548901 scopus 로고    scopus 로고
    • Observing Self-Assembled Lipid Nanoparticles Building Order and Complexity through Low-Energy Transformation Processes
    • X. Mulet Xiaojuan Gong Lynne J. Waddington Calum J. Drummond Observing Self-Assembled Lipid Nanoparticles Building Order and Complexity through Low-Energy Transformation Processes ACS Nano 2009 3 9 2789 2797
    • (2009) ACS Nano , vol.3 , Issue.9 , pp. 2789-2797
    • Mulet, X.1    Gong, X.2    Waddington, L.J.3    Drummond, C.J.4
  • 80
    • 77950338359 scopus 로고    scopus 로고
    • Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia
    • L. Li et al., Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia J. Controlled Release 2010 143 2 274 9
    • (2010) J. Controlled Release , vol.143 , Issue.2 , pp. 274-279
    • Li, L.1
  • 81
    • 0043207598 scopus 로고    scopus 로고
    • Disc formation in cholesterol-free liposomes during phase transition
    • L. M. Ickenstein et al., Disc formation in cholesterol-free liposomes during phase transition Biochim. Biophys. Acta, Biomembr. 2003 1614 2 135 8
    • (2003) Biochim. Biophys. Acta, Biomembr. , vol.1614 , Issue.2 , pp. 135-138
    • Ickenstein, L.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.