Pharmacokinetics & tissue distribution of temperature-sensitive liposomal doxorubicin in tumor-bearing mice triggered with mild hyperthermia

Biomaterials

Volumn 33, Issue 18, 2012, Pages 4608-4617

  Al Jamal, Wafa' T ^a   Al Ahmady, Zahraa S ^a   Kostarelos, Kostas ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Animal model; Drug delivery; Drug release; In vivo test; Liposomes; Phospholipid

Indexed keywords

ANIMAL MODEL; BLOOD CIRCULATION; DRUG RELEASE; DRUG RELEASE PROPERTIES; IN-VIVO TESTS; INTRAVENOUS ADMINISTRATION; LIPOSOMAL DOXORUBICIN; NORMAL CONDITION; PHARMACOLOGICAL PROFILES; RELEASE KINETICS; SERUM STABILITY; TEMPERATURE SENSITIVITY; TEMPERATURE-SENSITIVE; TISSUE DISTRIBUTIONS; TUMOR ACCUMULATION; TUMOR LOCALIZATION; ULTRA-FAST;

CARDIOVASCULAR SYSTEM; DRUG DELIVERY; ETHERS; HYPERTHERMIA THERAPY; LIPOSOMES; TUMORS;

PHOSPHOLIPIDS;

DOXORUBICIN; DRUG CARRIER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CIRCULATION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG EXTRAVASATION; DRUG MECHANISM; DRUG RELEASE; DRUG STABILITY; FEMALE; HYPERTHERMIA; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; TEMPERATURE SENSITIVITY; TISSUE DISTRIBUTION; TUMOR LOCALIZATION;

ANIMALS; CALORIMETRY, DIFFERENTIAL SCANNING; CELL LINE, TUMOR; DOXORUBICIN; FEMALE; HYPERTHERMIA, INDUCED; MELANOMA; MICE; MICE, INBRED C57BL; TEMPERATURE;

ANIMALIA; MUS;

EID: 84859831666     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.03.018     Document Type: Article

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