Delayed fracture healing and increased callus adiposity in a C57BL/6J Murine model of obesity-associated type 2 diabetes mellitus

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Brown, Matthew L ^a,b   Yukata, Kiminori ^a   Farnsworth, Christopher W ^a   Chen, Ding Geng ^a   Awad, Hani ^a,c   Hilton, Matthew J ^a   O'Keefe, Regis J ^a   Xing, Lianping ^a   Mooney, Robert A ^a   Zuscik, Michael J ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; CALLUS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE ASSOCIATION; FRACTURE NONUNION; GLUCOSE INTOLERANCE; IMMUNOHISTOCHEMISTRY; IMPAIRED GLUCOSE TOLERANCE; LIPID DIET; MALE; MORPHOMETRICS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; TIBIA FRACTURE; ANGIOGENESIS; ANIMAL; C57BL MOUSE; COMPLICATION; DIABETES MELLITUS, TYPE 2; DISEASE MODEL; FRACTURE; FRACTURE HEALING; GENE EXPRESSION; GENETICS; METABOLISM; MICRO-COMPUTED TOMOGRAPHY; ORGAN SIZE; PATHOLOGY;

ADIPOSITY; ANIMALS; BIOMECHANICAL PHENOMENA; BONY CALLUS; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; FRACTURE HEALING; FRACTURES, BONE; GENE EXPRESSION; GLUCOSE INTOLERANCE; MALE; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; OBESITY; ORGAN SIZE; PPAR GAMMA; X-RAY MICROTOMOGRAPHY;

EID: 84902580956     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099656     Document Type: Article

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