Thiolated Eudragit-based nanoparticles for oral insulin delivery: Preparation, characterization, and evaluation using intestinal epithelial cells in vitro

Macromolecular Bioscience

Volumn 14, Issue 6, 2014, Pages 842-852

  Zhang, Yan ^a,b   Du, Xuli ^a   Zhang, Yu ^a   Li, Guofei ^a   Cai, Cuifang ^a   Xu, Jinghua ^a   Tang, Xing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHENYANG UNIVERSITY   (China)

Author keywords

Caco 2 HT 29 co culture; drug delivery; insulin; permeation enhancer, thiolated nanoparticles

Indexed keywords

CONTROLLED DRUG DELIVERY; DRUG DELIVERY; NANOPARTICLES;

AVERAGE PARTICLE SIZE; COCULTURE; INTESTINAL EPITHELIAL CELLS; INTESTINAL EPITHELIUM; ORAL INSULIN DELIVERY; PARACELLULAR TRANSPORT; PERMEATION ENHANCEMENT; PERMEATION ENHANCERS;

INSULIN;

EUDRAGIT; GLUTATHIONE; INSULIN; NANOCARRIER; NANOPARTICLE; ANTIDIABETIC AGENT; METHYLMETHACRYLATE-METHACRYLIC ACID COPOLYMER; POLYMETHACRYLIC ACID DERIVATIVE;

ARTICLE; CACO 2 CELL LINE; CELL CULTURE; CELL TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN RELEASE; INTESTINE EPITHELIUM CELL; MEMBRANE TRANSPORT; PARTICLE SIZE; CHEMISTRY; CYTOLOGY; DRUG DELIVERY SYSTEM; EPITHELIUM CELL; INTESTINE MUCOSA; METABOLISM; ORAL DRUG ADMINISTRATION; PROCEDURES; TRANSPORT AT THE CELLULAR LEVEL;

ADMINISTRATION, ORAL; BIOLOGICAL TRANSPORT; CACO-2 CELLS; DRUG DELIVERY SYSTEMS; EPITHELIAL CELLS; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INTESTINAL MUCOSA; NANOPARTICLES; POLYMETHACRYLIC ACIDS;

EID: 84902543187     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201300515     Document Type: Article

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