Circulating angiogenic and inflammatory cytokine responses to acute aerobic exercise in trained and sedentary young men

European Journal of Applied Physiology

Volumn 114, Issue 7, 2014, Pages 1377-1384

  Landers Ramos, Rian Q ^a,c   Jenkins, Nathan T ^a   Spangenburg, Espen E ^a   Hagberg, James M ^a   Prior, Steven J ^b,c  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

Author keywords

Endurance exercise; Exercise training; Growth factors; Inflammation; Interleukin

Indexed keywords

ANGIOGENIC PROTEIN; AUTACOID; BIOLOGICAL MARKER; CYTOKINE;

ADOLESCENT; ADULT; BLOOD; COMPARATIVE STUDY; ENDURANCE; EXERCISE; HUMAN; MALE; OXYGEN CONSUMPTION; RUNNING; SEDENTARY LIFESTYLE; TIME; YOUNG ADULT;

ADOLESCENT; ADULT; ANGIOGENIC PROTEINS; BIOLOGICAL MARKERS; CYTOKINES; EXERCISE; HUMANS; INFLAMMATION MEDIATORS; MALE; OXYGEN CONSUMPTION; PHYSICAL ENDURANCE; RUNNING; SEDENTARY LIFESTYLE; TIME FACTORS; YOUNG ADULT;

EID: 84902543109     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-014-2861-6     Document Type: Article

References (41)

1. Adams V (2004) Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Arterioscler Thromb Vasc Biol 24:684-690. doi: 10.1161/01.ATV.0000124104.23702. a0
2. Adams V, Linke A, Breuckmann F et al (2008) Circulating progenitor cells decrease immediately after marathon race in advanced-age marathon runners. Eur J Cardiovasc Prev Rehabil 15:602-607. doi: 10.1097/HJR.0b013e328309c756
3. Ambarish V, Chandrashekara S, Suresh KP (2012) Moderate regular exercises reduce inflammatory response for physical stress. Indian J Physiol Pharmacol 56:7-14
4. American College of Sports Medicine (2009) ACSM's guidelines for exercise testing and prescription, 8th edn. Lippincott Williams & Wilkins, Baltimore
5. American College of Sports Medicine (2012) ACSM's health/fitness facility standards and guidelines, 4th edn. Human Kinetics, Champaign
6. Bailey AP, Shparago M, Gu J-W (2006) Exercise increases soluble vascular endothelial growth factor receptor-1 (sFlt-1) in circulation of healthy volunteers. Med Sci Monit 12:CR45-CR50
7. Blann AD, Belgore FM, McCollum CN et al (2002) Vascular endothelial growth factor and its receptor, Flt-1, in the plasma of patients with coronary or peripheral atherosclerosis, or Type II diabetes. Clin Sci 102:187-194
8. Croft L, Bartlett JD, MacLaren DPM et al (2009) High-intensity interval training attenuates the exercise-induced increase in plasma IL-6 in response to acute exercise. Appl Physiol Nutr Metab 34:1098-1107. doi: 10.1139/H09-117
9. Dewerchin M, Carmeliet P (2012) PlGF: a multitasking cytokine with disease-restricted Activity. Cold Spring Harb Perspect Med 2:a011056. doi: 10.1101/cshperspect.a011056
10. Dill DB, Costill DL (1974) Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol 37:247-248
11. Febbraio MA, Pedersen BK (2002) Muscle-derived interleukin-6: mechanisms for activation and possible biological roles. FASEB J 16:1335-1347. doi: 10.1096/fj.01-0876rev
12. Fischer CP (2004) Endurance training reduces the contraction-induced interleukin-6 mRNA expression in human skeletal muscle. Am J Physiol Endocrinol Metab 287:1189-1194. doi: 10.1152/ajpendo.00206.2004
13. Gigante B, Tarsitano M, Cimini V et al (2004) Placenta growth factor is not required for exercise-induced angiogenesis. Angiogenesis 7:277-284. doi: 10.1007/s10456-004-4179-1
14. Gokhale R, Chandrashekara S, Vasanthakumar KC (2007) Cytokine response to strenuous exercise in athletes and non-athletes - an adaptive response. Cytokine 40:123-127. doi: 10.1016/j.cyto.2007.08.006
15. Gomes EC, Silva AN, de Oliveira MR (2012) Oxidants, antioxidants, and the beneficial roles of exercise-induced production of reactive species. Oxid Med Cell Longev 2012:1-12. doi: 10.1152/japplphysiol.01202.2006
16. Gu JW, Santiago D, Olowe Y, Weinberger J (1997) Basic fibroblast growth factor as a biochemical marker of exercise-induced ischemia. Circulation 95:1165-1168
17. Heidemann J (2002) Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. J Biol Chem 278:8508-8515. doi: 10.1074/jbc.M208231200
18. Hoier B, Passos M, Bangsbo J, Hellsten Y (2013) Intense intermittent exercise provides weak stimulus for vascular endothelial growth factor secretion and capillary growth in skeletal muscle. Exp Physiol 98:585-597. doi: 10.1113/expphysiol.2012.067967
19. Jackson AS, Pollock ML (2004) Generalized equations for predicting body density of men. 1978. Br J Nutr 91:161-168
20. Jenkins NT, Landers RQ, Prior SJ et al (2011) Effects of acute and chronic endurance exercise on intracellular nitric oxide and superoxide in circulating CD34+ and CD34- cells. J Appl Physiol 111:929-937. doi: 10.1152/japplphysiol.00541.2011
21. Jensen L (2004) Effect of high intensity training on capillarization and presence of angiogenic factors in human skeletal muscle. J Physiol (Lond) 557:571-582. doi: 10.1113/jphysiol.2003.057711
22. Keller C (2005) Effect of exercise, training, and glycogen availability on IL-6 receptor expression in human skeletal muscle. J Appl Physiol 99:2075-2079. doi: 10.1152/japplphysiol.00590.2005
23. Kraus RM (2004) Circulating plasma VEGF response to exercise in sedentary and endurance-trained men. J Appl Physiol 96:1445-1450. doi: 10.1152/japplphysiol.01031.2003
24. Lieb W, Safa R, Benjamin EJ et al (2009) Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function. Eur Heart J 30:1121-1127. doi: 10.1093/eurheartj/ehp007
25. Luttun A, Brusselmans K, Fukao H et al (2002) Loss of placental growth factor protects mice against vascular permeability in pathological conditions. Biochem Biophys Res Commun 295:428-434
26. Mobius-Winkler S, Hilberg T, Menzel K et al (2009) Time-dependent mobilization of circulating progenitor cells during strenuous exercise in healthy individuals. J Appl Physiol 107:1943-1950. doi: 10.1152/japplphysiol. 00532.2009
27. Nielsen AR, Pedersen BK (2007) The biological roles of exercise-induced cytokines: IL-6, IL-8, and IL-15. Appl Physiol Nutr Metab 32:833-839. doi: 10.1139/H07-054
28. Nieman DC, Henson DA, Davis JM et al (2006) Blood leukocyte mRNA expression for IL-10, IL-1Ra, and IL-8, but not IL-6, increases after exercise. J Interferon Cytokine Res 26:668-674. doi: 10.1089/jir.2006.26.668
29. Nieman DC, Konrad M, Henson DA et al (2012) Variance in the acute inflammatory response to prolonged cycling is linked to exercise intensity. J Interferon Cytokine Res 32:12-17. doi: 10.1089/jir2011.0038
30. Ostrowski K, Hermann C, Bangash A et al (1998) A trauma-like elevation of plasma cytokines in humans in response to treadmill running. J Physiol (Lond) 513(Pt 3):889-894
31. Pedersen BK, Fischer CP (2007) Physiological roles of muscle-derived interleukin-6 in response to exercise. Curr Opin Clin Nutr Metab Care 10:265-271. doi: 10.1097/MCO.0b013e3280ebb5b3
32. Popa C, Netea MG, van Riel PLCM et al (2007) The role of TNF- in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res 48:751-762. doi: 10.1194/jlr.R600021-JLR200
33. Ronsen O, Lea T, Bahr R, Pedersen BK (2002) Enhanced plasma IL-6 and IL-1ra responses to repeated vs. single bouts of prolonged cycling in elite athletes. J Appl Physiol 92:2547-2553. doi: 10.1152/japplphysiol.01263.2001
34. Scott JPR, Sale C, Greeves JP et al (2011) Effect of exercise intensity on the cytokine response to an acute bout of running. Med Sci Sports Exerc 43:2297-2306. doi: 10.1249/MSS.0b013e31822113a9
35. Scott JPR, Sale C, Greeves JP et al (2013) Cytokine response to acute running in recreationally-active and endurance-trained men. Eur J Appl Physiol. doi: 10.1007/s00421-013-2615-x
36. Tanaka T, Kanda T, McManus BM et al (2001) Overexpression of interleukin-6 aggravates viral myocarditis: impaired increase in tumor necrosis factor-alpha. J Mol Cell Cardiol 33:1627-1635. doi: 10.1006/jmcc2001.1428
37. Trøseid M (2004) Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J 25:349-355. doi: 10.1016/j.ehj.2003.12.006
38. Vassilakopoulos T, Karatza M-H, Katsaounou P et al (2002) Antioxidants attenuate the plasma cytokine response to exercise in humans. J Appl Physiol 94:1025-1032. doi: 10.1152/japplphysiol.00735.2002
39. Wahl P, Zinner C, Achtzehn S et al (2010) Effects of acid-base balance and high or low intensity exercise on VEGF and bFGF. Eur J Appl Physiol 111:1405-1413. doi: 10.1007/s00421-010-1767-1
40. Weissgerber TL, Davies GAL, Roberts JM (2010) Modification of angiogenic factors by regular and acute exercise during pregnancy. J Appl Physiol 108:1217-1223. doi: 10.1152/japplphysiol.00008.2010
41. Wellen KE, Hotamisligil GS (2005) Inflammation, stress, and diabetes. J Clin Invest 115:1111-1119. doi: 10.1172/JCI25102DS1