-
1
-
-
38149085156
-
Langerhans cells are required for efficient presentation of topically applied hapten to T cells
-
Bennett CL, Noordegraaf M, Martina CA et al. (2007) Langerhans cells are required for efficient presentation of topically applied hapten to T cells. J Immunol 179: 6830-5
-
(2007)
J Immunol
, vol.179
, pp. 6830-6835
-
-
Bennett, C.L.1
Noordegraaf, M.2
Martina, C.A.3
-
2
-
-
1542313881
-
Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha
-
Boyman O, Hefti HP, Conrad C et al. (2004) Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha. J Exp Med 199: 731-6
-
(2004)
J Exp Med
, vol.199
, pp. 731-736
-
-
Boyman, O.1
Hefti, H.P.2
Conrad, C.3
-
3
-
-
37549051226
-
Identification of a novel population of Langerin+ dendritic cells
-
Bursch LS, Wang L, Igyarto B et al. (2007) Identification of a novel population of Langerin+ dendritic cells. J Exp Med 204: 3147-56
-
(2007)
J Exp Med
, vol.204
, pp. 3147-3156
-
-
Bursch, L.S.1
Wang, L.2
Igyarto, B.3
-
4
-
-
80755180843
-
Pivotal role of dermal IL-17-producing gammadelta T cells in skin inflammation
-
Cai Y, Shen X, Ding C et al. (2011) Pivotal role of dermal IL-17-producing gammadelta T cells in skin inflammation. Immunity 596-610
-
(2011)
Immunity
, pp. 596-610
-
-
Cai, Y.1
Shen, X.2
Ding, C.3
-
5
-
-
34547774225
-
Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
-
Capon F, Di Meglio P et al. (2007) Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet 122: 201-6
-
(2007)
Hum Genet
, vol.122
, pp. 201-206
-
-
Capon, F.1
Di Meglio, P.2
-
6
-
-
33751546237
-
IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
-
Chan JR, Blumenschein W, Murphy E et al. (2006) IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med 203: 2577-87
-
(2006)
J Exp Med
, vol.203
, pp. 2577-2587
-
-
Chan, J.R.1
Blumenschein, W.2
Murphy, E.3
-
7
-
-
0037434789
-
Interleukin-23 rather than interleukin- 12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua DJ, Sherlock J, Chen Y et al. (2003) Interleukin-23 rather than interleukin- 12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421: 744-8
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
-
8
-
-
77954143695
-
Innate IL-17-producing cells: The sentinels of the immune system
-
Cua DJ, Tato CM (2010) Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol 10: 479-89
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 479-489
-
-
Cua, D.J.1
Tato, C.M.2
-
9
-
-
67349230808
-
The IL-23/Th17 axis in the immunopathogenesis of psoriasis
-
Di Cesare A, Di Meglio P, Nestle FO (2009) The IL-23/Th17 axis in the immunopathogenesis of psoriasis. J Invest Dermatol 129: 1339-50
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1339-1350
-
-
Di Cesare, A.1
Di Meglio, P.2
Nestle, F.O.3
-
11
-
-
80054737381
-
Skin as a peripheral lymphoid organ: Revisiting the concept of skin-associated lymphoid tissues
-
Egawa G, Kabashima K (2011) Skin as a peripheral lymphoid organ: revisiting the concept of skin-associated lymphoid tissues. J Invest Dermatol 131: 2178-2178
-
(2011)
J Invest Dermatol
, vol.131
, pp. 2178-2178
-
-
Egawa, G.1
Kabashima, K.2
-
12
-
-
33845296923
-
Generalized psoriasis induced by topical treatment of actinic keratosis with imiquimod
-
Fanti PA, Dika E, Vaccari S et al. (2006) Generalized psoriasis induced by topical treatment of actinic keratosis with imiquimod. Int J Dermatol 45: 1464-1464
-
(2006)
Int J Dermatol
, vol.45
, pp. 1464-1464
-
-
Fanti, P.A.1
Dika, E.2
Vaccari, S.3
-
13
-
-
0033953110
-
CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: Blood and skin comparisons by flow cytometry
-
Ferenczi K, Burack L, Pope M et al. (2000) CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry. J Autoimmun 14:q63-78
-
(2000)
J Autoimmun
, vol.14
-
-
Ferenczi, K.1
Burack, L.2
Pope, M.3
-
14
-
-
37549030450
-
Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state
-
Ginhoux F, Collin MP, Bogunovic M et al. (2007) Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state. J Exp Med 204: 3133-46
-
(2007)
J Exp Med
, vol.204
, pp. 3133-3146
-
-
Ginhoux, F.1
Collin, M.P.2
Bogunovic, M.3
-
15
-
-
84873543022
-
IL-23-independent induction of IL-17 from gammadeltaT cells and innate lymphoid cells promotes experimental intraocular neovascularization
-
Hasegawa E, Sonoda KH, Shichita T et al. (2013) IL-23-independent induction of IL-17 from gammadeltaT cells and innate lymphoid cells promotes experimental intraocular neovascularization. J Immunol 190: 1778-87
-
(2013)
J Immunol
, vol.190
, pp. 1778-1787
-
-
Hasegawa, E.1
Sonoda, K.H.2
Shichita, T.3
-
16
-
-
84872597221
-
Update of immune events in the murine contact hypersensitivity model: Toward the understanding of allergic contact dermatitis
-
Honda T, Egawa G, Grabbe S et al. (2012) Update of immune events in the murine contact hypersensitivity model: toward the understanding of allergic contact dermatitis. J Invest Dermatol 133: 303-15
-
(2012)
J Invest Dermatol
, vol.133
, pp. 303-315
-
-
Honda, T.1
Egawa, G.2
Grabbe, S.3
-
17
-
-
80051906942
-
Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses
-
Igyarto BZ, Haley K, Ortner D et al. (2011) Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses. Immunity 35: 260-72
-
(2011)
Immunity
, vol.35
, pp. 260-272
-
-
Igyarto, B.Z.1
Haley, K.2
Ortner, D.3
-
18
-
-
0027985574
-
Epidermal turnover time
-
Iizuka H (1994) Epidermal turnover time. J Dermatol Sci 8: 215-7
-
(1994)
J Dermatol Sci
, vol.8
, pp. 215-217
-
-
Iizuka, H.1
-
19
-
-
84856234422
-
Early immune events in the induction of allergic contact dermatitis
-
Kaplan DH, Igyarto BZ, Gaspari AA (2012) Early immune events in the induction of allergic contact dermatitis. Nat Rev Immunol 12: 114-24
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 114-124
-
-
Kaplan, D.H.1
Igyarto, B.Z.2
Gaspari, A.A.3
-
20
-
-
28844492624
-
Epidermal langerhans celldeficient mice develop enhanced contact hypersensitivity
-
Kaplan DH, Jenison MC, Saeland S et al. (2005) Epidermal langerhans celldeficient mice develop enhanced contact hypersensitivity. Immunity 23: 611-20
-
(2005)
Immunity
, vol.23
, pp. 611-620
-
-
Kaplan, D.H.1
Jenison, M.C.2
Saeland, S.3
-
21
-
-
21144444056
-
Dynamics and function of Langerhans cells in vivo: Dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells
-
Kissenpfennig A, Henri S, Dubois B et al. (2005) Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity 22: 643-54
-
(2005)
Immunity
, vol.22
, pp. 643-654
-
-
Kissenpfennig, A.1
Henri, S.2
Dubois, B.3
-
22
-
-
33846889522
-
A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
-
Krueger GG, Langley RG, Leonardi C et al. (2007) A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N Engl J Med 356: 580-92
-
(2007)
N Engl J Med
, vol.356
, pp. 580-592
-
-
Krueger, G.G.1
Langley, R.G.2
Leonardi, C.3
-
23
-
-
58149316658
-
Induction of IL-17+ T cell trafficking and development by IFN-gamma: Mechanism and pathological relevance in psoriasis
-
Kryczek I, Bruce AT, Gudjonsson JE et al. (2008) Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis. J Immunol 181: 4733-41
-
(2008)
J Immunol
, vol.181
, pp. 4733-4741
-
-
Kryczek, I.1
Bruce, A.T.2
Gudjonsson, J.E.3
-
24
-
-
0347285359
-
Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
-
Lee E, Trepicchio WL, Oestreicher JL et al. (2004) Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 199: 125-30
-
(2004)
J Exp Med
, vol.199
, pp. 125-130
-
-
Lee, E.1
Trepicchio, W.L.2
Oestreicher, J.L.3
-
25
-
-
42149087160
-
Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells
-
Lowes MA, Kikuchi T, Fuentes-Duculan J et al. (2008) Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. J Invest Dermatol 128: 1207-11
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1207-1211
-
-
Lowes, M.A.1
Kikuchi, T.2
Fuentes-Duculan, J.3
-
26
-
-
81455141962
-
Epidermal CCR6+ gammadelta T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitis
-
Mabuchi T, Takekoshi T, Hwang ST (2011) Epidermal CCR6+ gammadelta T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitis. J Immunol 187: 5026-31
-
(2011)
J Immunol
, vol.187
, pp. 5026-5031
-
-
Mabuchi, T.1
Takekoshi, T.2
Hwang, S.T.3
-
27
-
-
2442658900
-
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease
-
Merad M, Hoffmann P, Ranheim E et al. (2004) Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat Med 10: 510-7
-
(2004)
Nat Med
, vol.10
, pp. 510-517
-
-
Merad, M.1
Hoffmann, P.2
Ranheim, E.3
-
28
-
-
54249130813
-
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte- response pathways
-
Nograles KE, Zaba LC, Guttman-Yassky E et al. (2008) Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte- response pathways. Br J Dermatol 159: 1092-102
-
(2008)
Br J Dermatol
, vol.159
, pp. 1092-1102
-
-
Nograles, K.E.1
Zaba, L.C.2
Guttman-Yassky, E.3
-
29
-
-
84867907486
-
Blockade of phosphatidylinositol 3- kinase (PI3K)delta or PI3Kgamma reduces IL-17 and ameliorates imiquimod- induced psoriasis-like dermatitis
-
Roller A, Perino A, Dapavo P et al. (2012) Blockade of phosphatidylinositol 3- kinase (PI3K)delta or PI3Kgamma reduces IL-17 and ameliorates imiquimod- induced psoriasis-like dermatitis. J Immunol 189: 4612-20
-
(2012)
J Immunol
, vol.189
, pp. 4612-4620
-
-
Roller, A.1
Perino, A.2
Dapavo, P.3
-
30
-
-
77349112874
-
Langerhans cells and more: Langerin-expressing dendritic cell subsets in the skin
-
Romani N, Clausen BE, Stoitzner P (2010) Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin. Immunol Rev 234: 120-41
-
(2010)
Immunol Rev
, vol.234
, pp. 120-141
-
-
Romani, N.1
Clausen, B.E.2
Stoitzner, P.3
-
31
-
-
0034120295
-
Imiquimod, a topical immune response modifier, induces migration of Langerhans cells
-
Suzuki H, Wang B, Shivji GM et al. (2000) Imiquimod, a topical immune response modifier, induces migration of Langerhans cells. J Invest Dermatol 114: 135-41
-
(2000)
J Invest Dermatol
, vol.114
, pp. 135-141
-
-
Suzuki, H.1
Wang, B.2
Shivji, G.M.3
-
32
-
-
0028036391
-
Superantigenic staphylococcal exotoxins induce T-cell proliferation in the presence of Langerhans cells or class II-bearing keratinocytes and stimulate keratinocytes to produce T-cell-activating cytokines
-
Tokura Y, Yagi J, O'Malley M et al. (1994) Superantigenic staphylococcal exotoxins induce T-cell proliferation in the presence of Langerhans cells or class II-bearing keratinocytes and stimulate keratinocytes to produce T-cell-activating cytokines. J Invest Dermatol 102: 31-8
-
(1994)
J Invest Dermatol
, vol.102
, pp. 31-38
-
-
Tokura, Y.1
Yagi, J.2
O'Malley, M.3
-
33
-
-
66949162673
-
Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis
-
van der Fits L, Mourits S, Voerman JS et al. (2009) Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. J Immunol 182: 5836-45
-
(2009)
J Immunol
, vol.182
, pp. 5836-5845
-
-
Van Der Fits, L.1
Mourits, S.2
Voerman, J.S.3
-
34
-
-
84875878203
-
Aldara activates TLR7- independent immune defence
-
Walter A, Schafer M, Cecconi V et al. (2013) Aldara activates TLR7- independent immune defence. Nat Commun 4:1560
-
(2013)
Nat Commun
, vol.4
, pp. 1560
-
-
Walter, A.1
Schafer, M.2
Cecconi, V.3
-
35
-
-
84879547366
-
Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice
-
Wohn C, Ober-Blobaum JL, Haak S et al. (2013) Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice. Proc Natl Acad Sci USA 110: 10723-8
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 10723-10728
-
-
Wohn, C.1
Ober-Blobaum, J.L.2
Haak, S.3
-
36
-
-
37549011317
-
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
-
Zaba LC, Cardinale I, Gilleaudeau P et al. (2007) Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J Exp Med 204: 3183-94
-
(2007)
J Exp Med
, vol.204
, pp. 3183-3194
-
-
Zaba, L.C.1
Cardinale, I.2
Gilleaudeau, P.3
|