메뉴 건너뛰기




Volumn 64, Issue 1, 2014, Pages 125-133

Identification of bona fide alternative renin transcripts expressed along cortical tubules and potential roles in promoting insulin resistance in vivo without significant plasma renin activity elevation

Author keywords

alternative transcript; insulin resistance; renin

Indexed keywords

COMPLEMENTARY DNA; INSULIN; MESSENGER RNA; RENIN;

EID: 84902535694     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.03394     Document Type: Article
Times cited : (13)

References (46)
  • 1
    • 85026145168 scopus 로고    scopus 로고
    • A memorial to Robert Tiegerstedt: The centennial of renin discovery
    • Inagami T. A memorial to Robert Tiegerstedt: the centennial of renin discovery. Hypertension. 1998;32: 953-957.
    • (1998) Hypertension , vol.32 , pp. 953-957
    • Inagami, T.1
  • 2
    • 0037059508 scopus 로고    scopus 로고
    • It's renin in the brain: Transgenic animals elucidate the brain renin angiotensin system
    • Bader M, Ganten D. It's renin in the brain: transgenic animals elucidate the brain renin angiotensin system. Circ Res. 2002;90: 8-10.
    • (2002) Circ Res , vol.90 , pp. 8-10
    • Bader, M.1    Ganten, D.2
  • 3
    • 0028010788 scopus 로고
    • Tissue angiotensin system in cardiovascular medicine. A paradigm shift?
    • Dzau VJ, Re R. Tissue angiotensin system in cardiovascular medicine. A paradigm shift? Circulation. 1994;89: 493-498.
    • (1994) Circulation , vol.89 , pp. 493-498
    • Dzau, V.J.1    Re, R.2
  • 4
    • 0028012543 scopus 로고
    • Renin is not synthesized by cardiac and extrarenal vascular tissues. A review of experimental evidence
    • von Lutterotti N, Catanzaro DF, Sealey JE, Laragh JH. Renin is not synthesized by cardiac and extrarenal vascular tissues. A review of experimental evidence. Circulation. 1994;89: 458-470.
    • (1994) Circulation , vol.89 , pp. 458-470
    • Von Lutterotti, N.1    Catanzaro, D.F.2    Sealey, J.E.3    Laragh, J.H.4
  • 5
    • 0025005906 scopus 로고
    • Morphology, physiology, and molecular biology of renin secretion
    • Hackenthal E, Paul M, Ganten D, Taugner R. Morphology, physiology, and molecular biology of renin secretion. Physiol Rev. 1990;70: 1067-1116.
    • (1990) Physiol Rev , vol.70 , pp. 1067-1116
    • Hackenthal, E.1    Paul, M.2    Ganten, D.3    Taugner, R.4
  • 6
    • 0025948361 scopus 로고
    • Structure, expression, and regulation of the murine renin genes
    • Sigmund CD, Gross KW. Structure, expression, and regulation of the murine renin genes. Hypertension. 1991;18: 446-457.
    • (1991) Hypertension , vol.18 , pp. 446-457
    • Sigmund, C.D.1    Gross, K.W.2
  • 8
    • 0344528550 scopus 로고    scopus 로고
    • An alternative transcript of the rat renin gene can result in a truncated prorenin that is transported into adrenal mitochondria
    • Clausmeyer S, Stürzebecher R, Peters J. An alternative transcript of the rat renin gene can result in a truncated prorenin that is transported into adrenal mitochondria. Circ Res. 1999;84: 337-344.
    • (1999) Circ Res , vol.84 , pp. 337-344
    • Clausmeyer, S.1    Stürzebecher, R.2    Peters, J.3
  • 9
    • 0033524747 scopus 로고    scopus 로고
    • Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing
    • Lee-Kirsch MA, Gaudet F, Cardoso MC, Lindpaintner K. Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing. Circ Res. 1999;84: 240-246.
    • (1999) Circ Res , vol.84 , pp. 240-246
    • Lee-Kirsch, M.A.1    Gaudet, F.2    Cardoso, M.C.3    Lindpaintner, K.4
  • 10
    • 0034729573 scopus 로고    scopus 로고
    • Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation
    • Sinn PL, Sigmund CD. Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation. Physiol Genomics. 2000;3: 25-31.
    • (2000) Physiol Genomics , vol.3 , pp. 25-31
    • Sinn, P.L.1    Sigmund, C.D.2
  • 13
    • 84857001776 scopus 로고    scopus 로고
    • Divergent mechanism regulating fluid intake and metabolism by the brain renin-angiotensin system
    • Sigmund CD. Divergent mechanism regulating fluid intake and metabolism by the brain renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol. 2012;302:R313-R320.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302
    • Sigmund, C.D.1
  • 14
    • 0021402417 scopus 로고
    • Evolution of aspartyl proteases by gene duplication: The mouse renin gene is organized in two homologous clusters of four exons
    • Holm I, Ollo R, Panthier JJ, Rougeon F. Evolution of aspartyl proteases by gene duplication: the mouse renin gene is organized in two homologous clusters of four exons. EMBO J. 1984;3: 557-562.
    • (1984) EMBO J , vol.3 , pp. 557-562
    • Holm, I.1    Ollo, R.2    Panthier, J.J.3    Rougeon, F.4
  • 15
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa H, Yamamura K, Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene. 1991;108: 193-199.
    • (1991) Gene , vol.108 , pp. 193-199
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 20
    • 84865151347 scopus 로고    scopus 로고
    • A fluorogenic near-infrared imaging agent for quantifying plasma and local tissue renin activity in vivo and ex vivo
    • Zhang J, Preda DV, Vasquez KO, et al. A fluorogenic near-infrared imaging agent for quantifying plasma and local tissue renin activity in vivo and ex vivo. Am J Physiol Renal Physiol. 2012;303:F593-F603.
    • (2012) Am J Physiol Renal Physiol , vol.303
    • Zhang, J.1    Preda, D.V.2    Vasquez, K.O.3
  • 21
    • 9644260562 scopus 로고    scopus 로고
    • Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus
    • Kubota N, Terauchi Y, Tobe K, et al. Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus. J Clin Invest. 2004;114: 917-927.
    • (2004) J Clin Invest , vol.114 , pp. 917-927
    • Kubota, N.1    Terauchi, Y.2    Tobe, K.3
  • 22
    • 83455219943 scopus 로고    scopus 로고
    • Reduced expression of angiotensin II and angiotensin receptor type 1 and type 2 in resistance arteries from nasal lesions in granulomatosis with polyangiitis (Wegener's granulomatosis)
    • Dimitrijevic I, Rissler P, Luts L, Edvinsson L. Reduced expression of angiotensin II and angiotensin receptor type 1 and type 2 in resistance arteries from nasal lesions in granulomatosis with polyangiitis (Wegener's granulomatosis). Scand J Rheumatol. 2011;40: 448-452.
    • (2011) Scand J Rheumatol , vol.40 , pp. 448-452
    • Dimitrijevic, I.1    Rissler, P.2    Luts, L.3    Edvinsson, L.4
  • 23
    • 84859650546 scopus 로고    scopus 로고
    • Partial restoration of cardio-vascular defects in a rescued severe model of spinal muscular atrophy
    • Shababi M, Habibi J, Ma L, Glascock JJ, Sowers JR, Lorson CL. Partial restoration of cardio-vascular defects in a rescued severe model of spinal muscular atrophy. J Mol Cell Cardiol. 2012;52: 1074-1082.
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 1074-1082
    • Shababi, M.1    Habibi, J.2    Ma, L.3    Glascock, J.J.4    Sowers, J.R.5    Lorson, C.L.6
  • 24
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burcklé C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest. 2002;109: 1417-1427.
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burcklé, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 27
    • 79551560598 scopus 로고    scopus 로고
    • Renin and prorenin receptor in hypertension: What's new?
    • Nguyen G. Renin and prorenin receptor in hypertension: what's new? Curr Hypertens Rep. 2011;13: 79-85.
    • (2011) Curr Hypertens Rep , vol.13 , pp. 79-85
    • Nguyen, G.1
  • 28
    • 82655181484 scopus 로고    scopus 로고
    • Prorenin receptor is essential for podocyte autophagy and survival
    • Riediger F, Quack I, Qadri F, et al. Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol. 2011;22: 2193-2202.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 2193-2202
    • Riediger, F.1    Quack, I.2    Qadri, F.3
  • 30
    • 0034463532 scopus 로고    scopus 로고
    • Tissue- specific expression of a rat renin transcript lacking the coding sequence for the prefragment and its stimulation by myocardial infarction
    • Clausmeyer S, Reinecke A, Farrenkopf R, Unger T, Peters J. Tissue- specific expression of a rat renin transcript lacking the coding sequence for the prefragment and its stimulation by myocardial infarction. Endocrinology. 2000;141: 2963-2970.
    • (2000) Endocrinology , vol.141 , pp. 2963-2970
    • Clausmeyer, S.1    Reinecke, A.2    Farrenkopf, R.3    Unger, T.4    Peters, J.5
  • 31
    • 0022922248 scopus 로고
    • New possibilities for intracellular renin and inactive renin now that the structure of the human renin gene has been elucidated
    • Morris BJ. New possibilities for intracellular renin and inactive renin now that the structure of the human renin gene has been elucidated. Clin Sci (Lond). 1986;71: 345-355.
    • (1986) Clin Sci (Lond) , vol.71 , pp. 345-355
    • Morris, B.J.1
  • 33
    • 0025218694 scopus 로고
    • Physical characterization of genetic rearrangements at the mouse renin loci
    • Abel KJ, Gross KW. Physical characterization of genetic rearrangements at the mouse renin loci. Genetics. 1990;124: 937-947.
    • (1990) Genetics , vol.124 , pp. 937-947
    • Abel, K.J.1    Gross, K.W.2
  • 35
    • 0025056570 scopus 로고
    • Site-directed mutagenesis of human prorenin. Substitution of three arginine residues in the propeptide with glutamine residues yields active prorenin
    • Yamauchi T, Nagahama M, Watanabe T, Ishizuka Y, Hori H, Murakami K. Site-directed mutagenesis of human prorenin. Substitution of three arginine residues in the propeptide with glutamine residues yields active prorenin. J Biochem. 1990;107: 27-31.
    • (1990) J Biochem , vol.107 , pp. 27-31
    • Yamauchi, T.1    Nagahama, M.2    Watanabe, T.3    Ishizuka, Y.4    Hori, H.5    Murakami, K.6
  • 37
    • 84863502684 scopus 로고    scopus 로고
    • Human prorenin structure sheds light on a novel mechanism of its autoinhibition and on its non-proteolytic activation by the (pro)renin receptor
    • Morales R, Watier Y, Böcskei Z. Human prorenin structure sheds light on a novel mechanism of its autoinhibition and on its non-proteolytic activation by the (pro)renin receptor. J Mol Biol. 2012;421: 100-111.
    • (2012) J Mol Biol , vol.421 , pp. 100-111
    • Morales, R.1    Watier, Y.2    Böcskei, Z.3
  • 38
    • 0025239301 scopus 로고
    • Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene
    • Mullins JJ, Peters J, Ganten D. Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature. 1990;344: 541-544.
    • (1990) Nature , vol.344 , pp. 541-544
    • Mullins, J.J.1    Peters, J.2    Ganten, D.3
  • 39
    • 0028205135 scopus 로고
    • Hypertension in the transgenic rat TGR(mRen-2)27 may be due to enhanced kinetics of the reaction between mouse renin and rat angiotensinogen
    • Tokita Y, Franco-Saenz R, Reimann EM, Mulrow PJ. Hypertension in the transgenic rat TGR(mRen-2)27 may be due to enhanced kinetics of the reaction between mouse renin and rat angiotensinogen. Hypertension. 1994;23: 422-427.
    • (1994) Hypertension , vol.23 , pp. 422-427
    • Tokita, Y.1    Franco-Saenz, R.2    Reimann, E.M.3    Mulrow, P.J.4
  • 40
    • 0028120888 scopus 로고
    • Effects of nephrectomy and adrenalectomy on the renin-angiotensin system of transgenic rats TGR(mRen2)27
    • Tokita Y, Franco-Saenz R, Mulrow PJ, Ganten D. Effects of nephrectomy and adrenalectomy on the renin-angiotensin system of transgenic rats TGR(mRen2)27. Endocrinology. 1994;134: 253-257.
    • (1994) Endocrinology , vol.134 , pp. 253-257
    • Tokita, Y.1    Franco-Saenz, R.2    Mulrow, P.J.3    Ganten, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.