Expression of MAK-V/Hunk in renal distal tubules and its possible involvement in proliferative suppression

American Journal of Physiology - Renal Physiology

Volumn 292, Issue 5, 2007, Pages

  Sakai, Masashi ^a,b   Tamura, Kouichi ^a   Tsurumi, Yuko ^a   Tanaka, Yutaka ^a   Koide, Yuichi ^a   Matsuda, Miyuki ^a   Ishigami, Tomoaki ^a   Yabana, Machiko ^a   Tokita, Yasuo ^b   Hiroi, Yukio ^c   Komuro, Issei ^d   Umemura, Satoshi ^a  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Fujisawa Municipal Hospital   (Japan)

^c HARVARD MEDICAL SCHOOL   (United States)

^d CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II; Renal epithelial cell; SNF1 protein kinase; Transforming growth factor

Indexed keywords

ADENOVIRUS VECTOR; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; BROXURIDINE; HORMONALLY UPREGULATED NEU ASSOCIATED KINASE; MESSENGER RNA; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADULTHOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CLONING; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; ENZYME LOCALIZATION; GENE TRANSFER; GENETIC TRANSCRIPTION; HORMONAL REGULATION; IN VIVO STUDY; KIDNEY DISTAL TUBULE; MALE; MOUSE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RAT; SALT INTAKE; SEQUENCE ANALYSIS;

EID: 34247853228     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00451.2006     Document Type: Article

References (36)

1. Becker W, Heukelbach J, Kentrup H, Joost HG. Molecular cloning and characterization of a novel mammalian protein kinase harboring a homology domain that defines a subfamily of serine/threonine kinases. Eur J Biochem 235: 736-743, 1996.
2. Chodosh LA, Gardner HP, Rajan JV, Stairs DB, Marquis ST, Leder PA. Protein kinase expression during murine mammary development. Dev Biol 219: 259-276, 2000.
3. Fraser S, Mount P, Hill R, Levidiotis V, Katsis F, Stapleton D, Kemp BE, Power DA. Regulation of the energy sensor AMP-activated protein kinase in the kidney by dietary salt intake and osmolality. Am J Physiol Renal Physiol 288: F578-F586, 2005.
4. Friedman PA, Gesek FA. Stimulation of calcium transport by amiloride in mouse distal convoluted tubule cells. Kidney Int 48: 1427-1434, 1995.
5. Gardner HP, Belka GK, Wertheim GB, Hartman JL, Ha SI, Gimotty PA, Marquis ST, Chodosh LA. Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland. Development 127: 4493-4509, 2000.
6. Gardner HP, Wertheim GB, Ha SI, Copeland NG, Gilbert DJ, Jenkins NA, Marquis ST, Chodosh LA. Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase. Genomics 63: 46-59, 2000.
7. Georgescu SP, Komuro I, Hiroi Y, Mizuno T, Kudoh S, Yamazaki T, Yazaki Y. Downregulation of polo-like kinase correlates with loss of proliferative ability of cardiac myocytes. J Mol Cell Cardiol 29: 929-937, 1997.
8. Gesek FA, Friedman PA. Sodium entry mechanisms in distal convoluted tubule cells. Am J Physiol Renal Fluid Electrolyte Physiol 268: F89-F98, 1995.
9. Gonzalez-Nunez D, Morales-Ruiz M, Leivas A, Hebert SC, Poch E. In vitro characterization of aldosterone and cAMP effects in mouse distal convoluted tubule cells. Am J Physiol Renal Physiol 286: F936-F944, 2004.
10. Gonzalez-Nunez D, Sole M, Natarajan R, Poch E. 12-Lipoxygenase metabolism in mouse distal convoluted tubule cells. Kidney Int 67: 178-186, 2005.
11. Guo S, Kemphues KJ. Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81: 611-620, 1995.
12. Guo S, Lopez-Ilasaca M, Dzau VJ. Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation. J Biol Chem 280: 12536-12541, 2005.
13. 1 receptor and its intracellular signal transduction in cultured vascular smooth muscle cells. FEBS Lett 579: 281-284, 2005.
14. Igarashi P, Shashikant CS, Thomson RB, Whyte DA, Liu-Chen S, Ruddle FH, Aronson PS. Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice. Am J Physiol Renal Physiol 277: F599-F610, 1999.
15. Ingert C, Grima M, Coquard C, Barthelmebs M, Imbs J. Effects of dietary salt changes on renal renin-angiotensin system in rats. Am J Physiol Renal Physiol 283: F995-F1002, 2002.
16. Jeck N, Schlingmann KP, Reinalter SC, Komhoff M, Peters M, Waldegger S, Seyberth HW. Salt handling in the distal nephron: lessons learned from inherited human disorders. Am J Physiol Regul Integr Comp Physiol 288: R782-R795, 2005.
17. Kihara M, Umemura S, Yabana M, Sumida Y, Nyui N, Tamura K, Kadota T, Kishida R, Murakami K, Fukamizu A, Ishii M. Dietary salt loading decreases the expressions of neuronal-type nitric oxide synthase and renin in the juxtaglomerular apparatus of angiotensinogen geneknockout mice. J Am Soc Nephrol 9: 355-362, 1998.
18. Korobko IV, Korobko EV, Kiselev SL. The MAK-V protein kinase regulates endocytosis in mouse. Mol Gen Genet 264: 411-418, 2000.
19. Loffing-Cueni DFS, Sauter D, Daidie D, Siegrist N, Meneton P, Staub O, Loffing J. Dietary sodium intake regulates the ubiquitin-protein ligase Nedd4-2 in the renal collecting system. J Am Soc Nephrol 17: 1264-1274, 2006.
20. Pizzonia JH, Gesek FA, Kennedy SM, Coutermarsh BA, Bacskai BJ, Friedman PA. Immunomagnetic separation, primary culture, and characterization of cortical thick ascending limb plus distal convoluted tubule cells from mouse kidney. In Vitro Cell Dev Biol 27A: 409-416, 1991.
21. Ruiz-Ortega M, Ruperez M, Esteban V, Rodriguez-Vita J, Sanchez-Lopez E, Carvajal G, Egido J. Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases. Nephrol Dial Transplant 21: 16-20, 2006.
22. Ruzov AS, Mertsalov IB, Meehan R, Kiselev SL, Buchman VL, Korobko IV. Cloning and developmental expression of MARK/Par-1/ MELK-related protein kinase xMAK-V in Xenopus laevis. Dev Genes Evol 214: 139-143, 2004.
23. Sadoshima J, Izumo S. Signal transduction pathways of angiotensin II-induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers. Circ Res 73: 424-438, 1993.
24. Schmid C, Castrop H, Reitbauer J, Della Bruna R, Kurtz A. Dietary salt intake modulates angiotensin II type 1 receptor gene expression. Hypertension 29: 923-929, 1997.
25. Sechi L, Griffin C, Giacchetti G, Valentin J, Llorens-Cortes C, Corvol P, Schambelan M. Tissue-specific regulation of type 1 angiotensin II receptor mRNA levels in the rat. Hypertension 28: 403-408, 1996.
26. Tamura K, Chen YE, Horiuchi M, Chen Q, Daviet L, Yang Z, Lopez-Ilasaca M, Mu H, Pratt RE, Dzau VJ. LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression. Proc Natl Acad Sci USA 97: 8513-8518, 2000.
27. Tamura K, Chen YE, Lopez-Ilasaca M, Daviet L, Tamura N, Ishigami T, Akishita M, Takasaki I, Tokita Y, Pratt RE, Horiuchi M, Dzau VJ, Umemura S. Molecular mechanism of fibronectin gene activation by cyclic stretch in vascular smooth muscle cells. J Biol Chem 275: 34619-34627, 2000.
28. 1R and ameliorates cardiomyocyte hypertrophy. FEBS Lett 579: 1579-1586, 2005.
29. Taniyama Y, Sato K, Sugawara A, Uruno A, Ikeda Y, Kudo M, Ito S, Takeuchi K. Renal tubule-specific transcription and chromosomal localization of rat thiazide-sensitive Na-Cl cotransporter gene. J Biol Chem 276: 26260-26268, 2001.
30. Thompson-Jaeger S, Francois J, Gaughran JP, Tatchell K. Deletion of SNF1 affects the nutrient response of yeast and resembles mutations which activate the adenylate cyclase pathway. Genetics 129: 697-706, 1991.
31. 1 receptor in the mouse renal tubules. Kidney Int 69: 488-494, 2006.
32. Vekaria RM, Shirley DG, Sevigny J, Unwin RJ. Immunolocalization of ectonucleotidases along the rat nephron. Am J Physiol Renal Physiol 290: F550-F560, 2006.
33. Whyte DA, Li C, Thomson RB, Nix SL, Zanjani R, Karp SL, Aronson PS, Igarashi P. Ksp-cadherin gene promoter. I. Characterization and renal epithelial cell-specific activity. Am J Physiol Renal Physiol 277: F587-F598, 1999.
34. Wolf G, Ziyadeh FN, Helmchen U, Zahner G, Schroeder R, Stahl RA. ANG II is a mitogen for a murine cell line isolated from medullary thick ascending limb of Henle's loop. Am J Physiol Renal Fluid Electrolyte Physiol 268: F940-F947, 1995.
35. Wolf G, Jablonski K, Schroeder R, Reinking R, Shankland SJ, Stahl RA. Angiotensin II-induced hypertrophy of proximal tubular cells requires p27Kip1. Kidney Int 64: 71-81, 2003.
36. Wolf G. Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway. Kidney Int 70:1914-1919, 2006.