Telmisartan reduces progressive oxidative stress and phosphorylated α-synuclein accumulation in stroke-resistant spontaneously hypertensive rats after transient middle cerebral artery occlusion

Journal of Stroke and Cerebrovascular Diseases

Volumn 23, Issue 6, 2014, Pages 1554-1563

  Sato, Kota ^a   Yamashita, Toru ^a   Kurata, Tomoko ^a   Lukic, Violeta ^a   Fukui, Yusuke ^a   Hishikawa, Nozomi ^a   Deguchi, Kentaro ^a   Abe, Koji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

oxidative stress; Parkinson's disease; phosphorylated synuclein; Spontaneously hypertensive rat; telmisartan

Indexed keywords

4 HYDROXYNONENAL; ADVANCED GLYCATION END PRODUCT; ALPHA SYNUCLEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TELMISARTAN; 4-HYDROXY-2-NONENAL; ALDEHYDE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE; NEUROPROTECTIVE AGENT; SYNUCLEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; BRAIN CORTEX; BRAIN DEPTH STIMULATION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CYTOPLASM; DRUG EFFECT; DRUG MEGADOSE; HIPPOCAMPUS; HYPERTENSION; IMMUNOHISTOLOGY; LOW DRUG DOSE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OXIDATIVE STRESS; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; STAINING; TRANSIENT MIDDLE CEREBRAL ARTERY OCCLUSION; ANIMAL; BLOOD PRESSURE; BRAIN; DRUG EFFECTS; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; PHOSPHORYLATION; WISTAR RAT;

ALDEHYDES; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZIMIDAZOLES; BENZOATES; BLOOD PRESSURE; BRAIN; GLYCOSYLATION END PRODUCTS, ADVANCED; HYPERTENSION; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PHOSPHORYLATION; RATS; RATS, INBRED SHR; RATS, WISTAR; SYNUCLEINS;

EID: 84902531967     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2013.12.051     Document Type: Article

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