Largely typical patterns of resting-state functional connectivity in high-functioning adults with autism

Cerebral Cortex

Volumn 24, Issue 7, 2014, Pages 1894-1905

  Tyszka, J Michael ^a   Kennedy, Daniel P ^b,c   Paul, Lynn K ^b   Adolphs, Ralph ^a,b  

^a California Institute of Technology HHMI   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c INDIANA UNIVERSITY   (United States)

Author keywords

autism spectrum disorder; functional magnetic resonance imaging; independent component analysis; resting state networks; temporal correlation

Indexed keywords

AMPHETAMINE PLUS DEXAMPHETAMINE; BUSPIRONE; FLUOXETINE; METHYLPHENIDATE; RISPERIDONE; RITALI; SERTRALINE; UNCLASSIFIED DRUG; OXYGEN;

ADULT; ANGULAR GYRUS; ARTICLE; AUTISM; AUTISM DIAGNOSTIC INTERVIEW REVISED; AUTISM DIAGNOSTIC OBSERVATION SCHEDULE; BOLD SIGNAL; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEAD MOVEMENT; HUMAN; IMAGE QUALITY; INFERIOR TEMPORAL GYRUS; INTELLIGENCE QUOTIENT; MALE; NEUROIMAGING; PRIORITY JOURNAL; RESTING STATE NETWORK; TEMPORAL CORTEX; BLOOD; BRAIN; BRAIN MAPPING; IMAGE PROCESSING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; REST; STATISTICS; VASCULARIZATION;

ADULT; AUTISTIC DISORDER; BRAIN; BRAIN MAPPING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; REST; STATISTICS AS TOPIC;

EID: 84902517382     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bht040     Document Type: Article

References (70)

1. Abell F, Krams M, Ashburner J, Passingham R, Friston K, Frackowiak R, Happe F, Frith C, Frith U. 1999. The neuroanatomy of autism: a voxel-based whole brain analysis of structural scans. Neuroreport. 10:1647-1651.
2. Andersson JL, Smith S, Jenkinson M. 2008. FNIRT-FMRIB non-linear image registration tool. 14th Annual Meeting of the Organization for Human Brain Mapping, Melbourne, Australia. 496 p.
3. Anderson JS, Druzgal TJ, Froehlich A, Dubray MB, Lange N, Alexander AL, Abildskov T, Nielsen JA, Cariello AN, Cooperrider JR et al. 2011. Decreased interhemispheric functional connectivity in autism. Cereb Cortex. 21:1134-1146.
4. Anderson JS, Nielsen JA, Froehlich AL, DuBray MB, Druzgal TJ, Cariello AN, Cooperrider JR, Zielinski BA, Ravichandran C, Fletcher PT et al. 2011. Functional connectivity magnetic resonance imaging classification of autism. Brain. 134:3742-3754.
5. Andersen LM, Naswall K, Manouilenko I, Nylander L, Edgar J, Ritvo RA, Ritvo E, Bejerot S. 2011. The Swedish version of the Ritvo autism and asperger diagnostic scale: revised (RAADS-R). A validation study of a rating scale for adults. J Autism Dev Disord. 41:1635-1645.
6. Assaf M, Jagannathan K, Calhoun VD, Miller L, Stevens MC, Sahl R, O'Boyle JG, Schultz RT, Pearlson GD. 2010. Abnormal functional connectivity of default mode sub-networks in autism spectrum disorder patients. Neuroimage. 53:247-256.
7. Barnea-Goraly N, Kwon H, Menon V, Eliez S, Lotspeich L, Reiss AL. 2004. White matter structure in autism: preliminary evidence from diffusion tensor imaging. Biol Psychiatry. 55:323-326.
8. Beckmann CF, Smith SM. 2004. Probabilistic independent component analysis for functional magnetic resonance imaging. IEEE Trans Med Imaging. 23:137-152.
9. Belmonte MK, Allen G, Beckel-Mitchener A, Boulanger LM, Carper RA, Webb SJ. 2004. Autism and abnormal development of brain connectivity. J Neurosci. 24:9228-9231.
10. Bennett CM, Wolford GL, Miller MB. 2009. The principled control of false positives in neuroimaging. Soc Cogn Affect Neurosci. 4:417-422.
11. Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe S et al. 2010. Toward discovery science of human brain function. Proc Natl Acad Sci USA. 107:4734-4739.
12. Bourgeron T. 2009. A synaptic trek to autism. Curr Opin Neurobiol. 19:231-234.
13. Calhoun VD, Adali T, Pearlson GD, Pekar JJ. 2001. A method for making group inferences from functional MRI data using independent component analysis. Hum Brain Mapp. 14:140-151.
14. Cherkassky VL, Kana RK, Keller TA, Just MA. 2006. Functional connectivity in a baseline resting-state network in autism. NeuroReport. 17:1687-1690.
15. Chevallier C, Kohls G, Troiani V, Brodkin ES, Schultz RT. 2012. The social motivation theory of autism. Trends Cogn Sci. 16: 231-239.
16. Courchesne E, Pierce K. 2005. Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection. Curr Opin Neurobiol. 15:225-230.
17. Damiano CR, Aloi J, Teadway M, Bodfish JW, Dichter GS. 2012. Adults with autism spectrum disorders exhibity decreased sensitivity to reward parameters when making effort-based decisions. J Neurodevelop Disord. 4:13.
18. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF. 2006. Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci USA. 103:13848-13853.
19. Di Martino A, Kelly C, Grzadzinski R, Zuo XN, Mennes M, Mairena MA, Lord C, Castellanos FX, Milham MP. 2011. Aberrant striatal functional connectivity in children with autism. Biol Psychiatry. 69:847-856.
20. Ebisch SJ, Gallese V, Willems RM, Mantini D, Groen WB, Romani GL, Buitelaar JK, Bekkering H. 2011. Altered intrinsic functional connectivity of anterior and posterior insula regions in highfunctioning participants with autism spectrum disorder. Hum Brain Mapp. 32:1013-1028.
21. Ecker C, Suckling J, Deoni SC, Lombardo MV, Bullmore ET, Baron- Cohen S, Catani M, Jezzard P, Barnes A, Bailey AJ et al. 2012. Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: a multicenter magnetic resonance imaging study. Arch Gen Psychiatry. 69:195-209.
22. Filippini N, MacIntosh BJ, Hough MG, Goodwin GM, Frisoni GB, Smith SM, Matthews PM, Beckmann CF, Mackay CE. 2009. Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele. Proc Natl Acad Sci USA. 106:7209-7214.
23. Fox MD, Zhang D, Snyder AZ, Raichle ME. 2009. The global signal and observed anticorrelated resting state brain networks. J Neurophysiol. 101:3270-3283.
24. Garber K. 2007. Neuroscience. Autism's cause may reside in abnormalities at the synapse. Science. 317:190-191.
25. Geschwind DH. 2011. Genetics of autism spectrum disorders. Trends Cogn Sci. 15:409-416.
26. Glessner JT, Wang K, Cai G, Korvatska O, Kim CE, Wood S, Zhang H, Estes A, Brune CW, Bradfield JP et al. 2009. Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature. 459:569-573.
27. Gotts SJ, Simmons WK, Milbury LA, Wallace GL, Cox RW, Martin A. 2012. Fractionation of social brain circuits in autism spectrum disorders. Brain. 135:2711-2725.
28. Greicius MD, Krasnow B, Reiss AL, Menon V. 2003. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci USA. 100:253-258.
29. Herbert MR, Ziegler DA, Makris N, Filipek PA, Kemper TL, Normandin JJ, Sanders HA, Kennedy DN, Caviness VS Jr. 2004. Localization of white matter volume increase in autism and developmental language disorder. Ann Neurol. 55:530-540.
30. Hinsby AM, Kiemer L, Karlberg EO, Lage K, Fausboll A, Juncker AS, Andersen JS, Mann M, Brunak S. 2006. A wiring of the human nucleolus. Mol Cell. 22:285-295.
31. Jennings RG, Van Horn JD. 2012. Publication bias in neuroimaging research: implications for meta-analyses. Neuroinformatics. 10:67-80.
32. Joel SE, Caffo BS, van Zijl PC, Pekar JJ. 2011. On the relationship between seed-based and ICA-based measures of functional connectivity. Magn Reson Med. 66:644-657.
33. Johnson RT, Dickersin K. 2007. Publication bias against negative results from clinical trials: three of the seven deadly sins. Nat Clin Pract Neurol. 3:590-591.
34. Just MA, Cherkassky VL, Keller TA, Kana RK, Minshew NJ. 2007. Functional and anatomical cortical underconnectivity in autism: evidence from an FMRI study of an executive function task and corpus callosum morphometry. Cereb Cortex. 17:951-961.
35. Just MA, Cherkassky VL, Keller TA, Minshew NJ. 2004. Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity. Brain. 127:1811-1821.
36. Kelly RE Jr, Alexopoulos GS, Wang Z, Gunning FM, Murphy CF, Morimoto SS, Kanellopoulos D, Jia Z, Lim KO, Hoptman MJ. 2010. Visual inspection of independent components: defining a procedure for artifact removal from fMRI data. J Neurosci Methods. 189:233-245.
37. Kennedy DP, Courchesne E. 2008. The intrinsic functional organization of the brain is altered in autism. Neuroimage. 39:1877-1885.
38. Kleinhans NM, Richards T, Sterling L, Stegbauer KC, Mahurin R, Johnson LC, Greenson J, Dawson G, Aylward E. 2008. Abnormal functional connectivity in autism spectrum disorders during face processing. Brain. 131:1000-1012.
39. Koshino H, Carpenter PA, Minshew NJ, Cherkassky VL, Keller TA, Just MA. 2005. Functional connectivity in an fMRI working memory task in high-functioning autism. Neuroimage. 24: 810-821.
40. Koshino H, Kana RK, Keller TA, Cherkassky VL, Minshew NJ, Just MA. 2008. fMRI investigation of working memory for faces in autism: visual coding and underconnectivity with frontal areas. Cereb Cortex. 18:289-300.
41. Lee M, Martin-Ruiz C, Graham A, Court J, Jaros E, Perry R, Iversen P, Bauman M, Perry E. 2002. Nicotinic receptor abnormalities in the cerebellar cortex in autism. Brain. 125:1483-1495.
42. Levitt P, Campbell DB. 2009. The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders. J Clin Invest. 119:747-754.
43. Lin A, Tsai K, Rangel A, Adolphs R. 2012. Reduced social preferences in autism: evidence from charitable donations. J Neurodevel Disord. 4:8.
44. Lord C, Risi S, Lambrecht L, Cook EH Jr, Leventhal BL, DiLavore PC, Pickles A, Rutter M. 2000. The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord. 30:205-223.
45. Lord C, Rutter M, Le Couteur A. 1994. Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord. 24:659-685.
46. MacKenzie-Graham A, Boline J, Toga AW. 2007. Brain atlases and neuroanatomic imaging. Methods Mol Biol. 401:183-194.
47. Madsen KM, Lauritsen MB, Pedersen CB, Thorsen P, Plesner AM, Andersen PH, Mortensen PB. 2003. Thimerosal and the occurrence of autism: negative ecological evidence from Danish population-based data. Pediatrics. 112:604-606.
48. Madsen KM, Lauritsen MB, Pedersen CB, Thorsen P, Plesner AM, Andersen PH, Mortensen PB. 2004. [Thimerosal and the occurrence of autism. Negative ecological evidence from Danish registry-data]. Ugeskr Laeger. 166:3291-3293.
49. Mazaika PK, Whitfield S, Cooper JC. 2005. Detection and repair of transient artifacts in fMRI data. Toronto, Canada: Human Brain Mapping. 581 p.
50. Minshew NJ, Williams DL. 2007. The new neurobiology of autism: cortex, connectivity, and neuronal organization. Arch Neurol. 64:945-950.
51. Monk CS, Peltier SJ, Wiggins JL, Weng SJ, Carrasco M, Risi S, Lord C. 2009. Abnormalities of intrinsic functional connectivity in autism spectrum disorders. Neuroimage. 47:764-772.
52. Muller RA, Shih P, Keehn B, Deyoe JR, Leyden KM, Shukla DK. 2011. Underconnected, but how? A survey of functional connectivity MRI studies in autism spectrum disorders. Cereb Cortex. 21:2233-2243.
53. Perry W, Minassian A, Lopez B, Maron L, Lincoln A. 2007. Sensorimotor gating deficits in adults with autism. Biol Psychiatry. 61:482-486.
54. Power JD, Barnes KA, Snyder AZ, Schlaggar BL, Petersen SE. 2012. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage. 59:2142-2154.
55. Rademacher J, Galaburda AM, Kennedy DN, Filipek PA, Caviness VS. 1992. Human cerebral cortex - localization, parcellation, and morphometry with magnetic-resonance-imaging. J Cogn Neurosci. 4:352-374.
56. Sbacchi S, Acquadro F, Calo I, Cali F, Romano V. 2010. Functional annotation of genes overlapping copy number variants in autistic patients: focus on axon pathfinding. Curr Genomics. 11:136-145.
57. Shirer WR, Ryali S, Rykhlevskaia E, Menon V, Greicius MD. 2012. Decoding subject-driven cognitive states with whole-brain connectivity patterns. Cereb Cortex. 22:158-165.
58. Smith SM, Fox PT, Miller KL, Glahn DC, Fox PM, Mackay CE, Filippini N, Watkins KE, Toro R, Laird AR et al. 2009. Correspondence of the brain's functional architecture during activation and rest. Proc Natl Acad Sci USA. 106:13040-13045.
59. State MW, Levitt P. 2011. The conundrums of understanding genetic risks for autism spectrum disorders. Nat Neurosci. 14:1499-1506.
60. Stevens WD, Buckner RL, Schacter DL. 2010. Correlated lowfrequency BOLD fluctuations in the resting human brain are modulated by recent experience in category-preferential visual regions. Cereb Cortex. 20:1997-2006.
61. Tyszka JM, Kennedy DP, Adolphs R, Paul LK. 2011. Intact bilateral resting-state networks in the absence of the corpus callosum. J Neurosci. 31:15154-15162.
62. Van Dijk KR, Hedden T, Venkataraman A, Evans KC, Lazar SW, Buckner RL. 2010. Intrinsic functional connectivity as a tool for human connectomics: theory, properties, and optimization. J Neurophysiol. 103:297-321.
63. Van Dijk KR, Sabuncu MR, Buckner RL. 2012. The influence of head motion on intrinsic functional connectivity MRI. Neuroimage. 59:431-438.
64. Veenstra-VanderWeele J, Muller CL, Iwamoto H, Sauer JE, Owens WA, Shah CR, Cohen J, Mannangatti P, Jessen T, Thompson BJ et al. 2012. Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior. Proc Natl Acad Sci USA. 109:5469-5474.
65. von dem Hagen EA, Nummenmaa L, Yu R, Engell AD, Ewbank MP, Calder AJ. 2011. Autism spectrum traits in the typical population predict structure and function in the posterior superior temporal sulcus. Cereb Cortex. 21:493-500.
66. von dem Hagen EA, Stoyanova RS, Baron-Cohen S, Calder AJ. 2012. Reduced functional connectivity within and between "social" resting state networks in autism spectrum conditions. Soc Cogn Affect Neurosci. [Epub ahead of print].
67. Waites AB, Stanislavsky A, Abbott DF, Jackson GD. 2005. Effect of prior cognitive state on resting state networks measured with functional connectivity. Hum Brain Mapp. 24:59-68.
68. Weinstein M, Ben-Sira L, Levy Y, Zachor DA, Ben Itzhak E, Artzi M, Tarrasch R, Eksteine PM, Hendler T, Ben Bashat D. 2011. Abnormal white matter integrity in young children with autism. Hum Brain Mapp. 32:534-543.
69. Weng SJ, Wiggins JL, Peltier SJ, Carrasco M, Risi S, Lord C, Monk CS. 2010. Alterations of resting state functional connectivity in the default network in adolescents with autism spectrum disorders. Brain Res. 1313:202-214.
70. Zhang Y, Brady M, Smith S. 2001. Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans Med Imaging. 20:45-57.