-
1
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007; 114(2):97-109.
-
(2007)
Acta Neuropathol.
, vol.114
, Issue.2
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
-
2
-
-
77952555038
-
Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
-
Van Meir EG, Hadjipanayis CG, Norden AD, et al. Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin. 2010;60(3):166-193.
-
(2010)
CA Cancer J Clin.
, vol.60
, Issue.3
, pp. 166-193
-
-
Van Meir, E.G.1
Hadjipanayis, C.G.2
Norden, A.D.3
-
3
-
-
48649086682
-
Mechanisms of disease: Temozolomide and glioblastoma-look to the future
-
Mrugala MM, Chamberlain MC. Mechanisms of disease: temozolomide and glioblastoma-look to the future. Nat Clin Pract Oncol. 2008;5(8):476-486.
-
(2008)
Nat Clin Pract Oncol.
, vol.5
, Issue.8
, pp. 476-486
-
-
Mrugala, M.M.1
Chamberlain, M.C.2
-
4
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987-996.
-
(2005)
N Engl J Med.
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
5
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Network TCGAR.
-
Network TCGAR. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008; 455(7216):1061-1068.
-
(2008)
Nature.
, vol.455
, Issue.7216
, pp. 1061-1068
-
-
-
6
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, Kharbanda S, Chen R, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006;9(3):157-173.
-
(2006)
Cancer Cell.
, vol.9
, Issue.3
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
-
7
-
-
79959996485
-
Pathway inhibition: Emerging molecular targets for treating glioblastoma
-
Wick W, Weller M, Weiler M, et al. Pathway inhibition: emerging molecular targets for treating glioblastoma. Neuro Oncol. 2011; 13(6):566-579.
-
(2011)
Neuro Oncol.
, vol.13
, Issue.6
, pp. 566-579
-
-
Wick, W.1
Weller, M.2
Weiler, M.3
-
8
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, et al. Stem cells, cancer, and cancer stem cells. Nature. 2001;414(6859):105-111.
-
(2001)
Nature.
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
-
9
-
-
84875240866
-
The multiple roles for Sox2 in stem cell maintenance and tumorigenesis
-
Liu K, Lin B, Zhao M, et al. The multiple roles for Sox2 in stem cell maintenance and tumorigenesis. Cell Signal. 2013;25(5): 1264-1271.
-
(2013)
Cell Signal.
, vol.25
, Issue.5
, pp. 1264-1271
-
-
Liu, K.1
Lin, B.2
Zhao, M.3
-
10
-
-
77956245743
-
Integrin alpha 6 regulates glioblastoma stem cells
-
Lathia JD, Gallagher J, Heddleston JM, et al. Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell. 2010;6(5): 421-432.
-
(2010)
Cell Stem Cell.
, vol.6
, Issue.5
, pp. 421-432
-
-
Lathia, J.D.1
Gallagher, J.2
Heddleston, J.M.3
-
11
-
-
41749118669
-
Identification of A2B5+CD133-tumor-initiating cells in adult human gliomas
-
discussion 514-515
-
Ogden AT, Waziri AE, Lochhead RA, et al. Identification of A2B5+CD133-tumor-initiating cells in adult human gliomas. Neurosurgery. 2008;62(2):505-514; discussion 514-515.
-
(2008)
Neurosurgery.
, vol.62
, Issue.2
, pp. 505-514
-
-
Ogden, A.T.1
Waziri, A.E.2
Lochhead, R.A.3
-
12
-
-
58649111264
-
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma
-
Read TA, Fogarty MP, Markant SL, et al. Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma. Cancer Cell. 2009;15(2):135-147.
-
(2009)
Cancer Cell.
, vol.15
, Issue.2
, pp. 135-147
-
-
Read, T.A.1
Fogarty, M.P.2
Markant, S.L.3
-
13
-
-
65349115320
-
SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
-
Son MJ, Woolard K, Nam DH, et al. SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell. 2009;4(5):440-452.
-
(2009)
Cell Stem Cell.
, vol.4
, Issue.5
, pp. 440-452
-
-
Son, M.J.1
Woolard, K.2
Nam, D.H.3
-
14
-
-
51049101689
-
Targeting cancer stem cells through L1CAM suppresses glioma growth
-
Bao S, Wu Q, Li Z, et al. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res. 2008;68(15):6043-6048.
-
(2008)
Cancer Res.
, vol.68
, Issue.15
, pp. 6043-6048
-
-
Bao, S.1
Wu, Q.2
Li, Z.3
-
15
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli R, Binda E, Orfanelli U, et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 2004;64(19):7011-7021.
-
(2004)
Cancer Res.
, vol.64
, Issue.19
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
-
16
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature. 2004;432(7015):396-401.
-
(2004)
Nature.
, vol.432
, Issue.7015
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
17
-
-
77649307110
-
Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks
-
Tabu K, Kimura T, Sasai K, et al. Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks. Mol Cancer. 2010;9:39.
-
(2010)
Mol Cancer.
, vol.9
, pp. 39
-
-
Tabu, K.1
Kimura, T.2
Sasai, K.3
-
18
-
-
84862297341
-
Current strategies for identification of glioma stem cells: Adequate or unsatisfactory?
-
Article ID 376894
-
Brescia P, Richichi C, Pelicci G. Current strategies for identification of glioma stem cells: adequate or unsatisfactory? J Oncol. 2012;2012: Article ID 376894.
-
(2012)
J Oncol.
, vol.2012
-
-
Brescia, P.1
Richichi, C.2
Pelicci, G.3
-
19
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010;17(1):98-110.
-
(2010)
Cancer Cell.
, vol.17
, Issue.1
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
20
-
-
46749102558
-
Genes controlling spread of breast cancer to lung "gang of 4."
-
Eltarhouny SA, Elsawy WH, Radpour R, et al. Genes controlling spread of breast cancer to lung "gang of 4." Exp Oncol. 2008;30(2):91-95.
-
(2008)
Exp Oncol.
, vol.30
, Issue.2
, pp. 91-95
-
-
Eltarhouny, S.A.1
Elsawy, W.H.2
Radpour, R.3
-
21
-
-
0031466502
-
Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4
-
Komurasaki T, Toyoda H, Uchida D, et al. Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4. Oncogene. 1997;15(23):2841-2848.
-
(1997)
Oncogene.
, vol.15
, Issue.23
, pp. 2841-2848
-
-
Komurasaki, T.1
Toyoda, H.2
Uchida, D.3
-
22
-
-
33750578614
-
Regulation of amphiregulin and epiregulin expression in human colonic subepithelial myofibroblasts
-
Inatomi O, Andoh A, Yagi Y, et al. Regulation of amphiregulin and epiregulin expression in human colonic subepithelial myofibroblasts. Int J Mol Med. 2006;18(3):497-503.
-
(2006)
Int J Mol Med.
, vol.18
, Issue.3
, pp. 497-503
-
-
Inatomi, O.1
Andoh, A.2
Yagi, Y.3
-
23
-
-
34147220392
-
Mediators of vascular remodelling co-opted for sequential steps in lung metastasis
-
Gupta GP, Nguyen DX, Chiang AC, et al. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature. 2007;446(7137):765- 770.
-
(2007)
Nature.
, vol.446
, Issue.7137
, pp. 765-770
-
-
Gupta, G.P.1
Nguyen, D.X.2
Chiang, A.C.3
-
24
-
-
4744366753
-
Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage
-
Lee D, Pearsall RS, Das S, et al. Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage. Mol Cell Biol. 2004;24(20): 8907-8916.
-
(2004)
Mol Cell Biol.
, vol.24
, Issue.20
, pp. 8907-8916
-
-
Lee, D.1
Pearsall, R.S.2
Das, S.3
-
25
-
-
84863006266
-
Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers
-
Yun J, Song SH, Park J, et al. Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers. Lab Invest. 2012;92(7):1033-1044.
-
(2012)
Lab Invest.
, vol.92
, Issue.7
, pp. 1033-1044
-
-
Yun, J.1
Song, S.H.2
Park, J.3
-
26
-
-
81155154258
-
EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction
-
Jin X, Yin J, Kim SH, et al. EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction. Cancer Res. 2011;71(22): 7125-7134.
-
(2011)
Cancer Res.
, vol.71
, Issue.22
, pp. 7125-7134
-
-
Jin, X.1
Yin, J.2
Kim, S.H.3
-
27
-
-
77957351780
-
Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis
-
Mazzoleni S, Politi LS, Pala M, et al. Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis. Cancer Res. 2010;70(19):7500-7513.
-
(2010)
Cancer Res.
, vol.70
, Issue.19
, pp. 7500-7513
-
-
Mazzoleni, S.1
Politi, L.S.2
Pala, M.3
-
28
-
-
60849117508
-
PTEN/PI3 K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
Bleau AM, Hambardzumyan D, Ozawa T, et al. PTEN/PI3 K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell. 2009;4(3): 226-235.
-
(2009)
Cell Stem Cell.
, vol.4
, Issue.3
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
-
29
-
-
39449135834
-
PI3 K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
-
Hambardzumyan D, Becher OJ, Rosenblum MK, et al. PI3 K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. Genes Dev. 2008;22(4):436-448.
-
(2008)
Genes Dev.
, vol.22
, Issue.4
, pp. 436-448
-
-
Hambardzumyan, D.1
Becher, O.J.2
Rosenblum, M.K.3
-
30
-
-
84873470179
-
Moesin is a glioma progression marker that induces proliferation and Wnt/beta-catenin pathway activation via interaction with CD44
-
Zhu X, Morales FC, Agarwal NK, et al. Moesin is a glioma progression marker that induces proliferation and Wnt/beta-catenin pathway activation via interaction with CD44. Cancer Res. 2013;73(3): 1142-1155.
-
(2013)
Cancer Res.
, vol.73
, Issue.3
, pp. 1142-1155
-
-
Zhu, X.1
Morales, F.C.2
Agarwal, N.K.3
-
31
-
-
84865712690
-
The MET oncogene is a functional marker of a glioblastoma stem cell subtype
-
De Bacco F, Casanova E, Medico E, et al. The MET oncogene is a functional marker of a glioblastoma stem cell subtype. Cancer Res. 2012;72(17):4537-4550.
-
(2012)
Cancer Res.
, vol.72
, Issue.17
, pp. 4537-4550
-
-
De Bacco, F.1
Casanova, E.2
Medico, E.3
-
32
-
-
79953757100
-
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3
-
Guryanova OA, Wu Q, Cheng L, et al. Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer Cell. 2011; 19(4):498-511.
-
(2011)
Cancer Cell.
, vol.19
, Issue.4
, pp. 498-511
-
-
Guryanova, O.A.1
Wu, Q.2
Cheng, L.3
-
33
-
-
70350212976
-
STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells
-
Sherry MM, Reeves A, Wu JK, et al. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells. 2009;27(10):2383-2392.
-
(2009)
Stem Cells.
, vol.27
, Issue.10
, pp. 2383-2392
-
-
Sherry, M.M.1
Reeves, A.2
Wu, J.K.3
-
34
-
-
70350497349
-
Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
-
Ikushima H, Todo T, Ino Y, et al. Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors. Cell Stem Cell. 2009;5(5): 504-514.
-
(2009)
Cell Stem Cell.
, vol.5
, Issue.5
, pp. 504-514
-
-
Ikushima, H.1
Todo, T.2
Ino, Y.3
-
35
-
-
84869084740
-
Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1
-
Fassl A, Tagscherer KE, Richter J, et al. Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1. Oncogene. 2012;31(44):4698-4708.
-
(2012)
Oncogene.
, vol.31
, Issue.44
, pp. 4698-4708
-
-
Fassl, A.1
Tagscherer, K.E.2
Richter, J.3
-
36
-
-
75349105363
-
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
-
Fan X, Khaki L, Zhu TS, et al. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells. 2010;28(1):5-16.
-
(2010)
Stem Cells.
, vol.28
, Issue.1
, pp. 5-16
-
-
Fan, X.1
Khaki, L.2
Zhu, T.S.3
-
37
-
-
84860163816
-
ErbB receptor tyrosine kinase/NF-kappaB signaling controls mammosphere formation in human breast cancer
-
Hinohara K, Kobayashi S, Kanauchi H, et al. ErbB receptor tyrosine kinase/NF-kappaB signaling controls mammosphere formation in human breast cancer. Proc Natl Acad Sci U S A. 2012;109(17): 6584-6589.
-
(2012)
Proc Natl Acad Sci U S A.
, vol.109
, Issue.17
, pp. 6584-6589
-
-
Hinohara, K.1
Kobayashi, S.2
Kanauchi, H.3
-
38
-
-
50649103493
-
Phase II study of carboplatin and erlotinib (Tarceva, OSI-774) in patients with recurrent glioblastoma
-
de Groot JF, Gilbert MR, Aldape K, et al. Phase II study of carboplatin and erlotinib (Tarceva, OSI-774) in patients with recurrent glioblastoma. J Neurooncol. 2008;90(1):89-97.
-
(2008)
J Neurooncol.
, vol.90
, Issue.1
, pp. 89-97
-
-
De Groot, J.F.1
Gilbert, M.R.2
Aldape, K.3
-
39
-
-
77953617053
-
Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme
-
Peereboom DM, Shepard DR, Ahluwalia MS, et al. Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme. J Neurooncol. 2010;98(1): 93-99.
-
(2010)
J Neurooncol.
, vol.98
, Issue.1
, pp. 93-99
-
-
Peereboom, D.M.1
Shepard, D.R.2
Ahluwalia, M.S.3
-
40
-
-
59149086517
-
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma
-
Prados MD, Chang SM, Butowski N, et al. Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma. J Clin Oncol. 2009;27(4):579-584.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.4
, pp. 579-584
-
-
Prados, M.D.1
Chang, S.M.2
Butowski, N.3
-
41
-
-
75049084471
-
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma
-
Reardon DA, Desjardins A, Vredenburgh JJ, et al. Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma. J Neurooncol. 2010;96(2):219-230.
-
(2010)
J Neurooncol.
, vol.96
, Issue.2
, pp. 219-230
-
-
Reardon, D.A.1
Desjardins, A.2
Vredenburgh, J.J.3
-
42
-
-
62449150719
-
Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC Brain Tumor Group study 26034
-
van den Bent MJ, Brandes AA, Rampling R, et al. Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC Brain Tumor Group study 26034. J Clin Oncol. 2009;27(8):1268-1274.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.8
, pp. 1268-1274
-
-
Van Den Bent, M.J.1
Brandes, A.A.2
Rampling, R.3
-
43
-
-
71349088046
-
A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoma multiforme: Clinical outcomes, pharmacokinetics and molecular correlation
-
Thiessen B, Stewart C, Tsao M, et al. A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoma multiforme: clinical outcomes, pharmacokinetics and molecular correlation. Cancer Chemother Pharmacol. 2010;65(2):353-361.
-
(2010)
Cancer Chemother Pharmacol.
, vol.65
, Issue.2
, pp. 353-361
-
-
Thiessen, B.1
Stewart, C.2
Tsao, M.3
-
44
-
-
0028862371
-
A eukaryotic transcriptional repressor with carboxypeptidase activity
-
He GP, Muise A, Li AW, et al. A eukaryotic transcriptional repressor with carboxypeptidase activity. Nature. 1995;378(6552):92-96.
-
(1995)
Nature.
, vol.378
, Issue.6552
, pp. 92-96
-
-
He, G.P.1
Muise, A.2
Li, A.W.3
-
45
-
-
0026061257
-
The C/EBP-binding region and adjacent sites regulate expression of the adipose P2 gene in human preadipocytes
-
Ro HS, Roncari DA. The C/EBP-binding region and adjacent sites regulate expression of the adipose P2 gene in human preadipocytes. Mol Cell Biol. 1991;11(4):2303-2306.
-
(1991)
Mol Cell Biol.
, vol.11
, Issue.4
, pp. 2303-2306
-
-
Ro, H.S.1
Roncari, D.A.2
-
46
-
-
84865289234
-
Identification of genomic targets of transcription factor Aebp1 and its role in survival of glioma cells
-
Ladha J, Sinha S, Bhat V, et al. Identification of genomic targets of transcription factor Aebp1 and its role in survival of glioma cells. Mol Cancer Res. 2012;10(8):1039-1051.
-
(2012)
Mol Cancer Res.
, vol.10
, Issue.8
, pp. 1039-1051
-
-
Ladha, J.1
Sinha, S.2
Bhat, V.3
-
47
-
-
0344823945
-
Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation
-
Akagi T, Sasai K, Hanafusa H. Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation. Proc Natl Acad Sci U S A. 2003;100(23): 13567-13572.
-
(2003)
Proc Natl Acad Sci U S A.
, vol.100
, Issue.23
, pp. 13567-13572
-
-
Akagi, T.1
Sasai, K.2
Hanafusa, H.3
-
48
-
-
79960318553
-
A population of BJ fibroblasts escaped from Ras-induced senescence susceptible to transformation
-
Kohsaka S, Sasai K, Takahashi K, et al. A population of BJ fibroblasts escaped from Ras-induced senescence susceptible to transformation. Biochem Biophys Res Commun. 2011;410(4):878-884.
-
(2011)
Biochem Biophys Res Commun.
, vol.410
, Issue.4
, pp. 878-884
-
-
Kohsaka, S.1
Sasai, K.2
Takahashi, K.3
|