-
1
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
DOI 10.1038/35102167
-
Reya T, Morrison SJ, Clarke MF, Weissman IL (2001) Stem cells, cancer, and cancer stem cells. Nature 414:105-111. (Pubitemid 33041634)
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
2
-
-
84922785910
-
Potential signaling pathways activated in cancer stem cells in breast cancer
-
ed Shostak S (InTech, Vienna, Austria)
-
Gotoh N (2011) Potential signaling pathways activated in cancer stem cells in breast cancer. Cancer Stem Cells Theories and Practice, ed Shostak S (InTech, Vienna, Austria), p 6.
-
(2011)
Cancer Stem Cells Theories and Practice
, pp. 6
-
-
Gotoh, N.1
-
3
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100: 3983-3988. (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
4
-
-
77954238710
-
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
-
Boiko AD, et al. (2010) Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature 466:133-137.
-
(2010)
Nature
, vol.466
, pp. 133-137
-
-
Boiko, A.D.1
-
5
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
DOI 10.1038/nm0797-730
-
Bonnet D, Dick JE (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3:730-737. (Pubitemid 27298715)
-
(1997)
Nature Medicine
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
6
-
-
69549114870
-
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
-
Chan KS, et al. (2009) Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci USA 106:14016-14021.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14016-14021
-
-
Chan, K.S.1
-
7
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
DOI 10.1073/pnas.0703478104
-
Dalerba P, et al. (2007) Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci USA 104:10158-10163. (Pubitemid 47175279)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.24
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.-K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
Hoey, T.7
Gurney, A.8
Huang, E.H.9
Simeone, D.M.10
Shelton, A.A.11
Parmiani, G.12
Castelli, C.13
Clarke, M.F.14
-
8
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
DOI 10.1038/nature05372, PII NATURE05372
-
O'Brien CA, Pollett A, Gallinger S, Dick JE (2007) A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445:106-110. (Pubitemid 46067310)
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
9
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
DOI 10.1073/pnas.0610117104
-
Prince ME, et al. (2007) Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA 104: 973-978. (Pubitemid 46154721)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
Wolf, G.T.4
Kaplan, M.J.5
Dalerba, P.6
Weissman, I.L.7
Clarke, M.F.8
Ailles, L.E.9
-
10
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, et al. (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63:5821-5828. (Pubitemid 37187480)
-
(2003)
Cancer Research
, vol.63
, Issue.18
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
11
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi M, et al. (2011) The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell 147:759-772.
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
-
12
-
-
73149110562
-
Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
-
Pece S, et al. (2010) Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 140:62-73.
-
(2010)
Cell
, vol.140
, pp. 62-73
-
-
Pece, S.1
-
13
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
DOI 10.1101/gad.1061803
-
Dontu G, et al. (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17:1253-1270. (Pubitemid 36583168)
-
(2003)
Genes and Development
, vol.17
, Issue.10
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.F.5
Kawamura, M.J.6
Wicha, M.S.7
-
14
-
-
21344454219
-
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
-
DOI 10.1158/0008-5472.CAN-05-0626
-
Ponti D, et al. (2005) Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 65:5506-5511. (Pubitemid 40911148)
-
(2005)
Cancer Research
, vol.65
, Issue.13
, pp. 5506-5511
-
-
Ponti, D.1
Costa, A.2
Zaffaroni, N.3
Pratesi, G.4
Petrangolini, G.5
Coradini, D.6
Pilotti, S.7
Pierotti, M.A.8
Daidone, M.G.9
-
15
-
-
36849078711
-
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
-
DOI 10.1016/j.cell.2007.10.054, PII S0092867407014171
-
Yu F, et al. (2007) let-7 Regulates self renewal and tumorigenicity of breast cancer cells. Cell 131:1109-1123. (Pubitemid 350235025)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
Gong, C.6
Huang, Y.7
Hu, X.8
Su, F.9
Lieberman, J.10
Song, E.11
-
16
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
-
Scheel C, et al. (2011) Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 145:926-940.
-
(2011)
Cell
, vol.145
, pp. 926-940
-
-
Scheel, C.1
-
17
-
-
79952412498
-
Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling
-
Hsing CH, et al. (2011) Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling. PLoS ONE 6: e17598.
-
(2011)
PLoS ONE
, vol.6
-
-
Hsing, C.H.1
-
18
-
-
78149495949
-
Inflammatory signaling pathways in self-renewing breast cancer stem cells
-
Hinohara K, Gotoh N (2010) Inflammatory signaling pathways in self-renewing breast cancer stem cells. Curr Opin Pharmacol 10:650-654.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 650-654
-
-
Hinohara, K.1
Gotoh, N.2
-
19
-
-
74249088301
-
Gene set enrichment analysis provides insight into novel signalling pathways in breast cancer stem cells
-
Murohashi M, et al. (2010) Gene set enrichment analysis provides insight into novel signalling pathways in breast cancer stem cells. Br J Cancer 102:206-212.
-
(2010)
Br J Cancer
, vol.102
, pp. 206-212
-
-
Murohashi, M.1
-
20
-
-
44149125709
-
The neuregulin family of genes and their multiple splice variants in breast cancer
-
Hayes NV, Gullick WJ (2008) The neuregulin family of genes and their multiple splice variants in breast cancer. J Mammary Gland Biol Neoplasia 13:205-214.
-
(2008)
J Mammary Gland Biol Neoplasia
, vol.13
, pp. 205-214
-
-
Hayes, N.V.1
Gullick, W.J.2
-
21
-
-
0029912447
-
NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice
-
Krane IM, Leder P (1996) NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice. Oncogene 12: 1781-1788. (Pubitemid 26146303)
-
(1996)
Oncogene
, vol.12
, Issue.8
, pp. 1781-1788
-
-
Krane, I.M.1
Leder, P.2
-
22
-
-
0037226817
-
Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo
-
Atlas E, et al. (2003) Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo. Mol Cancer Res 1:165-175. (Pubitemid 36330198)
-
(2003)
Molecular Cancer Research
, vol.1
, Issue.3
, pp. 165-175
-
-
Atlas, E.1
Cardillo, M.2
Mehmi, I.3
Zahedkargaran, H.4
Tang, C.5
Lupu, R.6
-
23
-
-
33747377549
-
Trastuzumab in combination with heregulin-activated Her-2 (erbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression
-
DOI 10.1200/JCO.2005.04.3489
-
Menendez JA, Mehmi I, Lupu R (2006) Trastuzumab in combination with heregulin-activated Her-2 (erbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression. J Clin Oncol 24:3735-3746. (Pubitemid 46622312)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.23
, pp. 3735-3746
-
-
Menendez, J.A.1
Mehmi, I.2
Lupu, R.3
-
24
-
-
2642517107
-
Co-expression of neuregulins 1,2,3 and 4 in human breast cancer
-
DOI 10.1002/path.1561
-
Dunn M, et al. (2004) Co-expression of neuregulins 1, 2, 3 and 4 in human breast cancer. J Pathol 203:672-680. (Pubitemid 38714104)
-
(2004)
Journal of Pathology
, vol.203
, Issue.2
, pp. 672-680
-
-
Dunn, M.1
Sinha, P.2
Campbell, R.3
Blackburn, E.4
Levinson, N.5
Rampaul, R.6
Bates, T.7
Humphreys, S.8
Gullick, W.J.9
-
25
-
-
54049096261
-
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
-
Korkaya H, Paulson A, Iovino F, Wicha MS (2008) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 27: 6120-6130.
-
(2008)
Oncogene
, vol.27
, pp. 6120-6130
-
-
Korkaya, H.1
Paulson, A.2
Iovino, F.3
Wicha, M.S.4
-
26
-
-
35848955428
-
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
-
DOI 10.1016/j.stem.2007.08.014, PII S1934590907001336
-
Ginestier C, et al. (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1:555-567. (Pubitemid 350056407)
-
(2007)
Cell Stem Cell
, vol.1
, Issue.5
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
Monville, F.4
Dutcher, J.5
Brown, M.6
Jacquemier, J.7
Viens, P.8
Kleer, C.G.9
Liu, S.10
Schott, A.11
Hayes, D.12
Birnbaum, D.13
Wicha, M.S.14
Dontu, G.15
-
27
-
-
43049165453
-
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
-
DOI 10.1016/j.cell.2008.03.027, PII S0092867408004443
-
Mani SA, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133:704-715. (Pubitemid 351636299)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
Eaton, E.Ng.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
28
-
-
33749320350
-
DHMEQ, a novel NF-kappaB inhibitor, induces apoptosis and cell-cycle arrest in human hepatoma cells
-
Nishimura D, et al. (2006) DHMEQ, a novel NF-kappaB inhibitor, induces apoptosis and cell-cycle arrest in human hepatoma cells. Int J Oncol 29:713-719.
-
(2006)
Int J Oncol
, vol.29
, pp. 713-719
-
-
Nishimura, D.1
-
29
-
-
60549111070
-
Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
-
Charafe-Jauffret E, et al. (2009) Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res 69: 1302-1313.
-
(2009)
Cancer Res
, vol.69
, pp. 1302-1313
-
-
Charafe-Jauffret, E.1
-
30
-
-
76649113726
-
CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
-
Ginestier C, et al. (2010) CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. J Clin Invest 120:485-497.
-
(2010)
J Clin Invest
, vol.120
, pp. 485-497
-
-
Ginestier, C.1
-
31
-
-
0033596121
-
Activators and target genes of Rel/NF-kappaB transcription factors
-
Pahl HL (1999) Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18:6853-6866.
-
(1999)
Oncogene
, vol.18
, pp. 6853-6866
-
-
Pahl, H.L.1
-
32
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M, et al. (2009) Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458:780-783.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
-
33
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by high-throughput screening
-
Gupta PB, et al. (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138:645-659.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
-
34
-
-
56749114437
-
Breast cancer stem cells: Implications for therapy of breast cancer
-
Morrison BJ, Schmidt CW, Lakhani SR, Reynolds BA, Lopez JA (2008) Breast cancer stem cells: Implications for therapy of breast cancer. Breast Cancer Res 10:210.
-
(2008)
Breast Cancer Res
, vol.10
, pp. 210
-
-
Morrison, B.J.1
Schmidt, C.W.2
Lakhani, S.R.3
Reynolds, B.A.4
Lopez, J.A.5
-
35
-
-
19944404432
-
Roles for neuregulins in human cancer
-
DOI 10.1007/s10585-004-6917-6
-
Stove C, Bracke M (2004) Roles for neuregulins in human cancer. Clin Exp Metastasis 21:665-684. (Pubitemid 40755007)
-
(2005)
Clinical and Experimental Metastasis
, vol.21
, Issue.8
, pp. 665-684
-
-
Stove, C.1
Bracke, M.2
-
36
-
-
77957591579
-
Targeting breast cancer stem cells
-
Liu S, Wicha MS (2010) Targeting breast cancer stem cells. J Clin Oncol 28:4006-4012.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4006-4012
-
-
Liu, S.1
Wicha, M.S.2
-
37
-
-
25844459154
-
NF-kappaB: Linking inflammation and immunity to cancer development and progression
-
DOI 10.1038/nri1703
-
Karin M, Greten FR (2005) NF-kappaB: Linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 5:749-759. (Pubitemid 41400849)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.10
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
38
-
-
18344390418
-
ERBB receptors and cancer: The complexity of targeted inhibitors
-
DOI 10.1038/nrc1609
-
Hynes NE, Lane HA (2005) ERBB receptors and cancer: The complexity of targeted inhibitors. Nat Rev Cancer 5:341-354. (Pubitemid 40637826)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
39
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, Hynes NE (2000) The ErbB signaling network: Receptor heterodimerization in development and cancer. EMBO J 19:3159-3167. (Pubitemid 30428195)
-
(2000)
EMBO Journal
, vol.19
, Issue.13
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
-
40
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
DOI 10.1200/JCO.20.3.719
-
Vogel CL, et al. (2002) Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 20:719-726. (Pubitemid 34111379)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.3
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
41
-
-
68349130357
-
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
-
kConFab
-
Lim E, et al.; kConFab (2009) Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med 15: 907-913.
-
(2009)
Nat Med
, vol.15
, pp. 907-913
-
-
Lim, E.1
|