A population of BJ fibroblasts escaped from Ras-induced senescence susceptible to transformation

Biochemical and Biophysical Research Communications

Volumn 410, Issue 4, 2011, Pages 878-884

  Kohsaka, Shinji ^a   Sasai, Ken ^a,b   Takahashi, Kenta ^a   Akagi, Tsuyoshi ^b   Tanino, Mishie ^a   Kimura, Taichi ^a   Nishihara, Hiroshi ^a   Tanaka, Shinya ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Kobe MI R and D Center ^*  (Japan)

Author keywords

Oncogene induced senescence; P16; P53; Ras; Stem cell

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; HYDROGEN PEROXIDE; LARGE T LYMPHOCYTE ANTIGEN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN P53; RETINOBLASTOMA PROTEIN; SMALL T LYMPHOCYTE ANTIGEN; T LYMPHOCYTE ANTIGEN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ANCHORAGE INDEPENDENT GROWTH; ANEUPLOIDY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER STEM CELL; CARCINOGENESIS; CELL AGING; CELL CYCLE ARREST; CELL POPULATION; CELL STRESS; CELL TRANSFORMATION; COLONY FORMATION; CONTROLLED STUDY; FEMALE; FIBROBLAST; GENE EXPRESSION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; ONCOGENE H RAS; ONCOGENE INDUCED SENESCENCE ESCAPED CELL; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; CELL AGING; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DIPLOIDY; FIBROBLASTS; GENES, RAS; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; STRESS, PHYSIOLOGICAL;

EID: 79960318553     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.06.082     Document Type: Article

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