Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair

Theranostics

Volumn 4, Issue 7, 2014, Pages 721-735

  Schreml, Stephan ^a   Meier, Robert J ^b   Kirschbaum, Michael ^c   Kong, Su Chii ^d   Gehmert, Sebastian ^a   Felthaus, Oliver ^a   Küchler, Sarah ^e   Sharpe, Justin R ^f   Wöltje, Kerstin ^c   Weiß, Katharina T ^a   Albert, Markus ^a   Seidl, Uwe ^a   Schröder, Josef ^a   Morsczeck, Christian ^a   Prantl, Lukas ^a   Duschl, Claus ^c   Pedersen, Stine F ^d   Gosau, Martin ^a   Berneburg, Mark ^a   Wolfbeis, Otto S ^b   Landthaler, Michael ^a   Babilas, Philipp ^a   more..

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e FREIE UNIVERSITÄT BERLIN   (Germany)

^f QUEEN VICTORIA HOSPITAL   (United Kingdom)

Author keywords

Cell migration; Fluorescence imaging; Gradient sensing; Proton transporters; Wound healing

Indexed keywords

SODIUM PROTON EXCHANGE PROTEIN 1; CATION TRANSPORT PROTEIN; FLUORESCENT DYE; SLC9A1 PROTEIN, HUMAN; SODIUM PROTON EXCHANGE PROTEIN;

ARTICLE; BIOCOMPATIBILITY; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CHRONIC WOUND; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMAGE ANALYSIS; IMAGE PROCESSING; KERATINOCYTE; LUMINESCENCE; MICROFLUIDICS; OXYGENATION; PH; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSOR; SIGNAL PROCESSING; WOUND HEALING; AGED; CELL HYPOXIA; CELL LINE; CELL MOTION; DRUG EFFECTS; EPITHELIZATION; FEMALE; FLUORESCENCE IMAGING; FLUORESCENCE MICROSCOPY; GENETIC PROCEDURES; GENETICS; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; PROCEDURES; VARICOSIS;

AGED; BIOSENSING TECHNIQUES; CATION TRANSPORT PROTEINS; CELL HYPOXIA; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; FLUORESCENT DYES; HUMANS; HYDROGEN-ION CONCENTRATION; KERATINOCYTES; MALE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; OPTICAL IMAGING; RE-EPITHELIALIZATION; SODIUM-HYDROGEN ANTIPORTER; VARICOSE ULCER;

EID: 84902438864     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.9052     Document Type: Article

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