-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay, J., et al. (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. International Journal of Cancer, 127(12), 2893-2917.
-
(2010)
International Journal of Cancer
, vol.127
, Issue.12
, pp. 2893-2917
-
-
Ferlay, J.1
-
3
-
-
77949437015
-
Colorectal cancer
-
Cunningham, D., et al. (2010). Colorectal cancer. Lancet, 375(9719), 1030-1047.
-
(2010)
Lancet
, vol.375
, Issue.9719
, pp. 1030-1047
-
-
Cunningham, D.1
-
4
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal, A., et al. (2009). Cancer statistics, 2009. CA: A Cancer Journal for Clinicians, 59(4), 225-249.
-
(2009)
CA: A Cancer Journal for Clinicians
, vol.59
, Issue.4
, pp. 225-249
-
-
Jemal, A.1
-
5
-
-
13744251436
-
Systemic therapy for colorectal cancer
-
Meyerhardt, J. A., & Mayer, R. J. (2005). Systemic therapy for colorectal cancer. New England Journal of Medicine, 352(5), 476-487.
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.5
, pp. 476-487
-
-
Meyerhardt, J.A.1
Mayer, R.J.2
-
6
-
-
0035145552
-
Fluorouracil and the new oral fluorinated pyrimidines
-
Kuhn, J. G. (2001). Fluorouracil and the new oral fluorinated pyrimidines. Annals of Pharmacotherapy, 35(2), 217-227.
-
(2001)
Annals of Pharmacotherapy
, vol.35
, Issue.2
, pp. 217-227
-
-
Kuhn, J.G.1
-
7
-
-
33749839931
-
New approaches to the adjuvant therapy of colon cancer
-
Benson, A. B, 3rd. (2006). New approaches to the adjuvant therapy of colon cancer. Oncologist, 11(9), 973-980.
-
(2006)
Oncologist
, vol.11
, Issue.9
, pp. 973-980
-
-
Benson 3rd, A.B.1
-
8
-
-
43249095213
-
Chemotherapy for metastatic gastric cancer: Past, present, and future
-
Ohtsu, A. (2008). Chemotherapy for metastatic gastric cancer: Past, present, and future. Journal of Gastroenterology, 43(4), 256-264.
-
(2008)
Journal of Gastroenterology
, vol.43
, Issue.4
, pp. 256-264
-
-
Ohtsu, A.1
-
9
-
-
81155125666
-
Icariin and its pharmaceutical efficacy: Research progress of molecular mechanism
-
Chen, Y., et al. (2011). Icariin and its pharmaceutical efficacy: Research progress of molecular mechanism. Zhong Xi Yi Jie He Xue Bao, 9(11), 1179-1184.
-
(2011)
Zhong Xi Yi Jie He Xue Bao
, vol.9
, Issue.11
, pp. 1179-1184
-
-
Chen, Y.1
-
10
-
-
34250670731
-
A novel anticancer agent, icaritin, induced cell growth inhibition, G1 arrest and mitochondrial transmembrane potential drop in human prostate carcinoma PC-3 cells
-
Huang, X., Zhu, D., & Lou, Y. (2007). A novel anticancer agent, icaritin, induced cell growth inhibition, G1 arrest and mitochondrial transmembrane potential drop in human prostate carcinoma PC-3 cells. European Journal of Pharmacology, 564(1-3), 26-36.
-
(2007)
European Journal of Pharmacology
, vol.564
, Issue.1-3
, pp. 26-36
-
-
Huang, X.1
Zhu, D.2
Lou, Y.3
-
11
-
-
77957932118
-
Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway
-
Li, S., et al. (2010). Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway. Cancer Letters, 298(2), 222-230.
-
(2010)
Cancer Letters
, vol.298
, Issue.2
, pp. 222-230
-
-
Li, S.1
-
12
-
-
1242337439
-
Cytotoxic effects of Coptis chinensis and Epimedium sagittatum extracts and their major constituents (berberine, coptisine and icariin) on hepatoma and leukaemia cell growth
-
Lin, C. C., et al. (2004). Cytotoxic effects of Coptis chinensis and Epimedium sagittatum extracts and their major constituents (berberine, coptisine and icariin) on hepatoma and leukaemia cell growth. Clinical and Experimental Pharmacology and Physiology, 31(1-2), 65-69.
-
(2004)
Clinical and Experimental Pharmacology and Physiology
, vol.31
, Issue.1-2
, pp. 65-69
-
-
Lin, C.C.1
-
13
-
-
77952322578
-
Icariin exterts negative effects on human gastric cancer cell invasion and migration by vasodilator-stimulated phosphoprotein via Rac1 pathway
-
Wang, Y., et al. (2010). Icariin exterts negative effects on human gastric cancer cell invasion and migration by vasodilator-stimulated phosphoprotein via Rac1 pathway. European Journal of Pharmacology, 635(1-3), 40-48.
-
(2010)
European Journal of Pharmacology
, vol.635
, Issue.1-3
, pp. 40-48
-
-
Wang, Y.1
-
14
-
-
84873547035
-
Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-kappaB
-
Zhang, D. C., et al. (2013). Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-kappaB. Acta Pharmacologica Sinica, 34(2), 301-308.
-
(2013)
Acta Pharmacologica Sinica
, vol.34
, Issue.2
, pp. 301-308
-
-
Zhang, D.C.1
-
15
-
-
79953795924
-
In vitro sequence-dependent synergism between paclitaxel and gefitinib in human lung cancer cell lines
-
Cheng, H., et al. (2011). In vitro sequence-dependent synergism between paclitaxel and gefitinib in human lung cancer cell lines. Cancer Chemotherapy and Pharmacology, 67(3), 637-646.
-
(2011)
Cancer Chemotherapy and Pharmacology
, vol.67
, Issue.3
, pp. 637-646
-
-
Cheng, H.1
-
16
-
-
2942709705
-
Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis
-
Takada, Y., Khuri, F. R., & Aggarwal, B. B. (2004). Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis. Journal of Biological Chemistry, 279(25), 26287-26299.
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.25
, pp. 26287-26299
-
-
Takada, Y.1
Khuri, F.R.2
Aggarwal, B.B.3
-
17
-
-
84862777510
-
Sorafenib sensitizes human colorectal carcinoma to radiation via suppression of NF-kappaB expression in vitro and in vivo
-
Kuo, Y. C., et al. (2012). Sorafenib sensitizes human colorectal carcinoma to radiation via suppression of NF-kappaB expression in vitro and in vivo. Biomedicine & Pharmacotherapy, 66(1), 12-20.
-
(2012)
Biomedicine & Pharmacotherapy
, vol.66
, Issue.1
, pp. 12-20
-
-
Kuo, Y.C.1
-
18
-
-
37849041521
-
Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro
-
Csaki, C., et al. (2008). Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro. Biochemical Pharmacology, 75(3), 677-687.
-
(2008)
Biochemical Pharmacology
, vol.75
, Issue.3
, pp. 677-687
-
-
Csaki, C.1
-
19
-
-
80051484401
-
Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: Role of the phosphatidylinositol 3-kinase/Akt pathway
-
Buhrmann, C., et al. (2011). Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: Role of the phosphatidylinositol 3-kinase/Akt pathway. Journal of Biological Chemistry, 286(32), 28556-28566.
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.32
, pp. 28556-28566
-
-
Buhrmann, C.1
-
20
-
-
78651460233
-
Gambogic acid enhances proteasome inhibitor-induced anticancer activity
-
Huang, H., et al. (2011). Gambogic acid enhances proteasome inhibitor-induced anticancer activity. Cancer Letters, 301(2), 221-228.
-
(2011)
Cancer Letters
, vol.301
, Issue.2
, pp. 221-228
-
-
Huang, H.1
-
21
-
-
84878240247
-
Synergistic antitumor effect of 5-fluorouracil in combination with parthenolide in human colorectal cancer
-
Kim, S. L., et al. (2013). Synergistic antitumor effect of 5-fluorouracil in combination with parthenolide in human colorectal cancer. Cancer Letters, 335(2), 479-486.
-
(2013)
Cancer Letters
, vol.335
, Issue.2
, pp. 479-486
-
-
Kim, S.L.1
-
22
-
-
84874290423
-
Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-kappaB and Src protein kinase signaling pathways
-
Shakibaei, M., et al. (2013). Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-kappaB and Src protein kinase signaling pathways. PLoS One, 8(2), e57218.
-
(2013)
PLoS One
, vol.8
, Issue.2
-
-
Shakibaei, M.1
-
23
-
-
84865386840
-
Effect of NF-kappaB inhibitors on the chemotherapy-induced apoptosis of the colon cancer cell line HT-29
-
Liu, T., et al. (2012). Effect of NF-kappaB inhibitors on the chemotherapy-induced apoptosis of the colon cancer cell line HT-29. Exp Ther Med, 4(4), 716-722.
-
(2012)
Exp Ther Med
, vol.4
, Issue.4
, pp. 716-722
-
-
Liu, T.1
-
24
-
-
0033451738
-
TNF-induced signaling in apoptosis
-
Rath, P. C., & Aggarwal, B. B. (1999). TNF-induced signaling in apoptosis. Journal of Clinical Immunology, 19(6), 350-364.
-
(1999)
Journal of Clinical Immunology
, vol.19
, Issue.6
, pp. 350-364
-
-
Rath, P.C.1
Aggarwal, B.B.2
-
25
-
-
0028082285
-
Sugar, meat, and fat intake, and non-dietary risk factors for colon cancer incidence in Iowa women (United States)
-
Bostick, R. M., et al. (1994). Sugar, meat, and fat intake, and non-dietary risk factors for colon cancer incidence in Iowa women (United States). Cancer Causes and Control, 5(1), 38-52.
-
(1994)
Cancer Causes and Control
, vol.5
, Issue.1
, pp. 38-52
-
-
Bostick, R.M.1
-
26
-
-
70350109231
-
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status
-
Poynter, J. N., et al. (2009). Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status. Cancer Epidemiology Biomarkers Prevention, 18(10), 2745-2750.
-
(2009)
Cancer Epidemiology Biomarkers Prevention
, vol.18
, Issue.10
, pp. 2745-2750
-
-
Poynter, J.N.1
-
27
-
-
0036828668
-
Biochemical modulation of 5-fluorouacil through dihydropyrimidine dehydrogenase inhibition: A Southwest Oncology Group phase II trial of eniluracil and 5-fluorouracil in advanced resistant colorectal cancer
-
Leichman, C. G., et al. (2002). Biochemical modulation of 5-fluorouacil through dihydropyrimidine dehydrogenase inhibition: A Southwest Oncology Group phase II trial of eniluracil and 5-fluorouracil in advanced resistant colorectal cancer. Investigational New Drugs, 20(4), 419-424.
-
(2002)
Investigational New Drugs
, vol.20
, Issue.4
, pp. 419-424
-
-
Leichman, C.G.1
-
28
-
-
0028036652
-
Chronomodulated versus fixed-infusion-rate delivery of ambulatory chemotherapy with oxaliplatin, fluorouracil, and folinic acid (leucovorin) in patients with colorectal cancer metastases: A randomized multi-institutional trial
-
Levi, F. A., et al. (1994). Chronomodulated versus fixed-infusion-rate delivery of ambulatory chemotherapy with oxaliplatin, fluorouracil, and folinic acid (leucovorin) in patients with colorectal cancer metastases: A randomized multi-institutional trial. Journal of the National Cancer Institute, 86(21), 1608-1617.
-
(1994)
Journal of the National Cancer Institute
, vol.86
, Issue.21
, pp. 1608-1617
-
-
Levi, F.A.1
-
29
-
-
3142689614
-
Expression of p65 gene in experimental colon cancer under the influence of 5-fluorouracil given alone and in combination with hormonal modulation
-
Melen-Mucha, G., et al. (2004). Expression of p65 gene in experimental colon cancer under the influence of 5-fluorouracil given alone and in combination with hormonal modulation. Neoplasma, 51(4), 319-324.
-
(2004)
Neoplasma
, vol.51
, Issue.4
, pp. 319-324
-
-
Melen-Mucha, G.1
-
30
-
-
0022624956
-
Combination chemotherapy (5-fluorouracil, methyl-CCNU, mitomycin C) versus 5-fluorouracil alone for advanced previously untreated colorectal carcinoma. A phase III study of the Piedmont Oncology Association
-
Richards, F, 2nd, et al. (1986). Combination chemotherapy (5-fluorouracil, methyl-CCNU, mitomycin C) versus 5-fluorouracil alone for advanced previously untreated colorectal carcinoma. A phase III study of the Piedmont Oncology Association. Journal of Clinical Oncology, 4(4), 565-570.
-
(1986)
Journal of Clinical Oncology
, vol.4
, Issue.4
, pp. 565-570
-
-
Richards 2nd, F.1
-
31
-
-
52949085860
-
Combined effects of 5-fluorouracil, folinic acid and oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: Pharmacological basis to develop an active antitumor immunochemotherapy
-
Prete, S. P., et al. (2008). Combined effects of 5-fluorouracil, folinic acid and oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: Pharmacological basis to develop an active antitumor immunochemotherapy. J Exp Clin Cancer Res, 27, 5.
-
(2008)
J Exp Clin Cancer Res
, vol.27
, pp. 5
-
-
Prete, S.P.1
-
32
-
-
33646383886
-
Combination therapy of intraarterial 5-fluorouracil and systemic interferon-alpha for advanced hepatocellular carcinoma with portal venous invasion
-
Obi, S., et al. (2006). Combination therapy of intraarterial 5-fluorouracil and systemic interferon-alpha for advanced hepatocellular carcinoma with portal venous invasion. Cancer, 106(9), 1990-1997.
-
(2006)
Cancer
, vol.106
, Issue.9
, pp. 1990-1997
-
-
Obi, S.1
-
33
-
-
79953291925
-
Synergistic antitumor effect of dichloroacetate in combination with 5-fluorouracil in colorectal cancer
-
Tong, J., et al. (2011). Synergistic antitumor effect of dichloroacetate in combination with 5-fluorouracil in colorectal cancer. Journal of Biomedicine and Biotechnology, 2011, 740564.
-
(2011)
Journal of Biomedicine and Biotechnology
, vol.2011
, pp. 740564
-
-
Tong, J.1
-
34
-
-
33645999706
-
NF-kappaB and IKK as therapeutic targets in cancer
-
Kim, H. J., Hawke, N., & Baldwin, A. S. (2006). NF-kappaB and IKK as therapeutic targets in cancer. Cell Death and Differentiation, 13(5), 738-747.
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.5
, pp. 738-747
-
-
Kim, H.J.1
Hawke, N.2
Baldwin, A.S.3
-
35
-
-
84862291483
-
Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in pancreatic cancer both in vitro and in vivo
-
Wang, Y. W., et al. (2012). Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in pancreatic cancer both in vitro and in vivo. Journal of Cancer Research and Clinical Oncology, 138(5), 785-797.
-
(2012)
Journal of Cancer Research and Clinical Oncology
, vol.138
, Issue.5
, pp. 785-797
-
-
Wang, Y.W.1
-
36
-
-
65249141108
-
Constitutive NF-kappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth
-
Sakamoto, K., et al. (2009). Constitutive NF-kappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth. Clinical Cancer Research, 15(7), 2248-2258.
-
(2009)
Clinical Cancer Research
, vol.15
, Issue.7
, pp. 2248-2258
-
-
Sakamoto, K.1
-
37
-
-
4544342570
-
Nuclear factor-kappaB: The enemy within
-
Aggarwal, B. B. (2004). Nuclear factor-kappaB: The enemy within. Cancer Cell, 6(3), 203-208.
-
(2004)
Cancer Cell
, vol.6
, Issue.3
, pp. 203-208
-
-
Aggarwal, B.B.1
-
38
-
-
0032905030
-
Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB
-
Wang, C. Y., et al. (1999). Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nature Medicine, 5(4), 412-417.
-
(1999)
Nature Medicine
, vol.5
, Issue.4
, pp. 412-417
-
-
Wang, C.Y.1
-
39
-
-
0036964816
-
Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization
-
Bharti, A. C., & Aggarwal, B. B. (2002). Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization. Annals of the New York Academy of Sciences, 973, 392-395.
-
(2002)
Annals of the New York Academy of Sciences
, vol.973
, pp. 392-395
-
-
Bharti, A.C.1
Aggarwal, B.B.2
-
40
-
-
0030271387
-
NF-kappa B: Ten years after
-
Baeuerle, P. A., & Baltimore, D. (1996). NF-kappa B: Ten years after. Cell, 87(1), 13-20.
-
(1996)
Cell
, vol.87
, Issue.1
, pp. 13-20
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
41
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet, B., & Gelinas, C. (1999). Aberrant rel/nfkb genes and activity in human cancer. Oncogene, 18(49), 6938-6947.
-
(1999)
Oncogene
, vol.18
, Issue.49
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
-
42
-
-
84872872093
-
(3S)-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid from Cichorium endivia. L induces apoptosis of human colorectal cancer HCT-8 cells
-
Wang, F. X., et al. (2012). (3S)-1, 2, 3, 4-Tetrahydro-beta-carboline-3-carboxylic acid from Cichorium endivia. L induces apoptosis of human colorectal cancer HCT-8 cells. Molecules, 18(1), 418-429.
-
(2012)
Molecules
, vol.18
, Issue.1
, pp. 418-429
-
-
Wang, F.X.1
-
43
-
-
84871574859
-
Deguelin, an Akt inhibitor, down-regulates NF-kappaB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice
-
Kang, H. W., et al. (2012). Deguelin, an Akt inhibitor, down-regulates NF-kappaB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice. Digestive Diseases and Sciences, 57(11), 2873-2882.
-
(2012)
Digestive Diseases and Sciences
, vol.57
, Issue.11
, pp. 2873-2882
-
-
Kang, H.W.1
-
44
-
-
42249102138
-
Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products
-
Kunnumakkara, A. B., et al. (2008). Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products. Clinical Cancer Research, 14(7), 2128-2136.
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.7
, pp. 2128-2136
-
-
Kunnumakkara, A.B.1
-
45
-
-
69549084702
-
Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity
-
Sandur, S. K., et al. (2009). Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity. International Journal of Radiation Oncology Biology Physics, 75(2), 534-542.
-
(2009)
International Journal of Radiation Oncology Biology Physics
, vol.75
, Issue.2
, pp. 534-542
-
-
Sandur, S.K.1
-
46
-
-
77249117637
-
Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines
-
Guo, X., et al. (2010). Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines. Cancer Letters, 290(1), 104-113.
-
(2010)
Cancer Letters
, vol.290
, Issue.1
, pp. 104-113
-
-
Guo, X.1
-
47
-
-
77953533783
-
Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin
-
Jani, T. S., et al. (2010). Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin. Journal of Biological Chemistry, 285(25), 19162-19172.
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.25
, pp. 19162-19172
-
-
Jani, T.S.1
-
48
-
-
70350497687
-
Invasion associated up-regulation of nuclear factor kappaB target genes in colorectal cancer
-
Horst, D., et al. (2009). Invasion associated up-regulation of nuclear factor kappaB target genes in colorectal cancer. Cancer, 115(21), 4946-4958.
-
(2009)
Cancer
, vol.115
, Issue.21
, pp. 4946-4958
-
-
Horst, D.1
|