Modeling of a new tubercular maltosyl transferase, GlgE, study of its binding sites and virtual screening

Molecular Biology Reports

Volumn 41, Issue 6, 2014, Pages 3549-3560

  Sengupta, Soumi ^a   Roy, Debjani ^b   Bandyopadhyay, Sanghamitra ^a  

^a INDIAN STATISTICAL INSTITUTE   (India)

^b BOSE INSTITUTE   (India)

Author keywords

Binding site; Drug target; Homology modeling; Maltosyl transferase; Tuberculosis; Virtual screening

Indexed keywords

3 O ALPHA DEXTRO GLUCOPYRANOSYL DEXTRO FRUCTOSE; AMYLASE; AMYLASE INHIBITOR; BACTERIAL ENZYME; CYSTEINE; DISULFIDE; FRUCTOSE; HOMODIMER; MALTOSE; MONOMER; PROTEIN GLGE; TRANSFERASE; TUBERCULAR MALTOSYLTRANSFERASE; UNCLASSIFIED DRUG; GLUCOSYLTRANSFERASE; MALTOSYLTRANSFERASE; TUBERCULOSTATIC AGENT;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DISULFIDE BOND; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE; MATHEMATICAL COMPUTING; MOLECULAR DOCKING; MOLECULAR MODEL; PROTEIN DOMAIN; PROTEIN FAMILY; STREPTOMYCES; STREPTOMYCES CEOLICOLOR; VIRTUAL REALITY; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; HUMAN; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; STREPTOMYCES COELICOLOR;

MYCOBACTERIUM TUBERCULOSIS; STREPTOMYCES;

ALPHA-AMYLASES; ANTITUBERCULAR AGENTS; BINDING SITES; CATALYTIC DOMAIN; GLUCOSYLTRANSFERASES; HUMANS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; STREPTOMYCES COELICOLOR;

EID: 84902368566     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-014-3068-y     Document Type: Article

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